ATE224714T1 - Behandlung von tinnitus mit neuroprotektiven wirkstoffen - Google Patents
Behandlung von tinnitus mit neuroprotektiven wirkstoffenInfo
- Publication number
- ATE224714T1 ATE224714T1 AT96306198T AT96306198T ATE224714T1 AT E224714 T1 ATE224714 T1 AT E224714T1 AT 96306198 T AT96306198 T AT 96306198T AT 96306198 T AT96306198 T AT 96306198T AT E224714 T1 ATE224714 T1 AT E224714T1
- Authority
- AT
- Austria
- Prior art keywords
- neuroprotective
- actives
- treating tinnitus
- tinnitus
- treating
- Prior art date
Links
- 208000009205 Tinnitus Diseases 0.000 title abstract 2
- 231100000886 tinnitus Toxicity 0.000 title abstract 2
- 230000000324 neuroprotective effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US385595P | 1995-09-15 | 1995-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE224714T1 true ATE224714T1 (de) | 2002-10-15 |
Family
ID=21707919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96306198T ATE224714T1 (de) | 1995-09-15 | 1996-08-27 | Behandlung von tinnitus mit neuroprotektiven wirkstoffen |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5716961A (de) |
| EP (1) | EP0768086B1 (de) |
| JP (1) | JP3038155B2 (de) |
| KR (1) | KR970014765A (de) |
| CN (1) | CN1104892C (de) |
| AT (1) | ATE224714T1 (de) |
| AU (1) | AU697679B2 (de) |
| CA (1) | CA2185512C (de) |
| DE (1) | DE69623899T2 (de) |
| DK (1) | DK0768086T3 (de) |
| ES (1) | ES2181853T3 (de) |
| IL (1) | IL119207A (de) |
| MY (1) | MY119375A (de) |
| NZ (1) | NZ299376A (de) |
| PT (1) | PT768086E (de) |
| TW (1) | TW450807B (de) |
| ZA (1) | ZA967746B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9804885D0 (en) | 1998-03-06 | 1998-04-29 | Merck Sharp & Dohme | Therapeutic combination |
| GB9821179D0 (en) * | 1998-09-30 | 1998-11-25 | Merck Sharp & Dohme | Therapeutic use |
| FR2787028B1 (fr) * | 1998-12-15 | 2002-10-18 | Aventis Pharma Sa | Utilisation du riluzole dans le traitement des traumatismes acoustiques |
| IL145451A0 (en) * | 1999-04-07 | 2002-06-30 | Pfizer Prod Inc | Use of cyp2d6 inhibitors in combination therapies |
| US6586446B1 (en) | 1999-10-15 | 2003-07-01 | Bristol-Myers Squibb Company | Bicyclic and tricyclic amines as modulators of chemokine receptor activity |
| US6784200B2 (en) * | 2000-10-13 | 2004-08-31 | Bristol-Myers Squibb Pharma Company | Bicyclic and tricyclic amines as modulators of chemokine receptor activity |
| YU27801A (sh) * | 2000-04-28 | 2003-04-30 | Pfizer Products Inc. | Postupak za dobijanje trihidrata mezilatne soli 1-(4- hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)-1-propanola i korisnih intermedijera |
| DE10048969A1 (de) * | 2000-08-23 | 2002-03-14 | Mueller Schwefe Gerhard | Verwendung von Flupirtin zur Tinnitusbehandlung |
| IL145584A0 (en) | 2000-10-02 | 2002-06-30 | Pfizer Prod Inc | Nmda nr2b antagonists for treatment |
| UA73619C2 (en) * | 2000-12-13 | 2005-08-15 | Pfizer Prod Inc | Stable pharmaceutical compositions of nmda receptor agonist (variants) and method of treatment |
| SE0100344D0 (sv) * | 2001-02-05 | 2001-02-05 | Jan Nordmark | New Use |
| DE60100055T2 (de) * | 2001-03-21 | 2003-07-24 | Schwarz Pharma Ag | Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen |
| US6743921B2 (en) * | 2002-01-24 | 2004-06-01 | Dsm Catalytica Pharmaceuticals, Inc. | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds |
| US7589110B2 (en) * | 2002-09-06 | 2009-09-15 | Durect Corporation | Delivery of modulators of glutamate-mediated neurotransmission to the inner ear |
| US7785653B2 (en) * | 2003-09-22 | 2010-08-31 | Innovational Holdings Llc | Method and apparatus for loading a beneficial agent into an expandable medical device |
| US8268866B2 (en) | 2004-03-29 | 2012-09-18 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US9072662B2 (en) | 2004-03-29 | 2015-07-07 | Auris Medical Ag | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US20060063802A1 (en) * | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| CA2620374C (en) * | 2005-09-28 | 2012-12-11 | Thomas Meyer | Pharmaceutical compositions for the treatment of inner ear disorders |
| WO2009033079A1 (en) * | 2007-09-07 | 2009-03-12 | Xenoport, Inc. | Externally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| TW200924746A (en) * | 2007-09-07 | 2009-06-16 | Xenoport Inc | Complex pantoic acid ester neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use |
| US20090099253A1 (en) * | 2007-10-15 | 2009-04-16 | Xenoport, Inc. | Internally Masked Neopentyl Sulfonyl Ester Cyclization Release Prodrugs of Acamprosate, Compositions Thereof, and Methods of Use |
| US8454877B2 (en) * | 2009-04-03 | 2013-06-04 | Pelican Products, Inc. | Method and apparatus for molding an article |
| WO2011145062A1 (en) | 2010-05-21 | 2011-11-24 | Link Research & Grants Corporation | Treatment of tinnitus and related auditory dysfunctions |
| US20130230586A1 (en) | 2010-10-02 | 2013-09-05 | Link Research & Grants Corporation | Treatment of Tinnitus and Related Auditory Dysfunctions |
| US8648198B2 (en) | 2011-01-19 | 2014-02-11 | Cold Spring Harbor Laboratory | Phenylethanolamine-based NMDA receptor antagonists |
| US8920855B1 (en) | 2012-10-30 | 2014-12-30 | Setem Hemth, Inc | Methods of topically treating tinnitus and related disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990014087A1 (en) * | 1989-05-17 | 1990-11-29 | Pfizer Inc. | 2-piperidino-1-alkanol derivatives as antiischemic agents |
| FI934566L (fi) * | 1991-04-18 | 1993-10-15 | Pfizer | Prodrug-estrar av fenol-2-piperidino-1-alkanoler |
| EP0542689B1 (de) * | 1991-11-15 | 1998-09-23 | Phafag Aktiengesellschaft | Verwendung von 1-(aminoalkyl)-3-Quinoxalin-2-on Derivaten zur Herstellung von neuroprotektiven Mitteln |
| GB9400680D0 (en) * | 1994-01-14 | 1994-03-09 | Sandoz Ltd | Improvements in or relating to organic compounds |
-
1996
- 1996-06-11 TW TW085107025A patent/TW450807B/zh not_active IP Right Cessation
- 1996-08-27 DK DK96306198T patent/DK0768086T3/da active
- 1996-08-27 AT AT96306198T patent/ATE224714T1/de not_active IP Right Cessation
- 1996-08-27 DE DE69623899T patent/DE69623899T2/de not_active Expired - Fee Related
- 1996-08-27 EP EP96306198A patent/EP0768086B1/de not_active Expired - Lifetime
- 1996-08-27 PT PT96306198T patent/PT768086E/pt unknown
- 1996-08-27 ES ES96306198T patent/ES2181853T3/es not_active Expired - Lifetime
- 1996-09-05 IL IL11920796A patent/IL119207A/en not_active IP Right Cessation
- 1996-09-09 US US08/709,996 patent/US5716961A/en not_active Expired - Fee Related
- 1996-09-12 JP JP8262343A patent/JP3038155B2/ja not_active Expired - Fee Related
- 1996-09-13 CA CA002185512A patent/CA2185512C/en not_active Expired - Fee Related
- 1996-09-13 AU AU65635/96A patent/AU697679B2/en not_active Ceased
- 1996-09-13 CN CN96112326A patent/CN1104892C/zh not_active Expired - Fee Related
- 1996-09-13 NZ NZ299376A patent/NZ299376A/en unknown
- 1996-09-13 MY MYPI96003783A patent/MY119375A/en unknown
- 1996-09-13 ZA ZA9607746A patent/ZA967746B/xx unknown
- 1996-09-14 KR KR1019960039978A patent/KR970014765A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0768086B1 (de) | 2002-09-25 |
| CA2185512A1 (en) | 1997-03-16 |
| KR970014765A (ko) | 1997-04-28 |
| IL119207A0 (en) | 1996-12-05 |
| DK0768086T3 (da) | 2002-10-14 |
| ZA967746B (en) | 1998-03-13 |
| EP0768086A1 (de) | 1997-04-16 |
| PT768086E (pt) | 2003-01-31 |
| MX9603819A (es) | 1997-07-31 |
| ES2181853T3 (es) | 2003-03-01 |
| IL119207A (en) | 2004-05-12 |
| MY119375A (en) | 2005-05-31 |
| JP3038155B2 (ja) | 2000-05-08 |
| CN1104892C (zh) | 2003-04-09 |
| DE69623899D1 (de) | 2002-10-31 |
| CA2185512C (en) | 2000-08-08 |
| JPH09124482A (ja) | 1997-05-13 |
| NZ299376A (en) | 2000-07-28 |
| CN1149454A (zh) | 1997-05-14 |
| DE69623899T2 (de) | 2003-01-23 |
| AU697679B2 (en) | 1998-10-15 |
| AU6563596A (en) | 1997-03-20 |
| US5716961A (en) | 1998-02-10 |
| TW450807B (en) | 2001-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0768086 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |