ATE298004T1 - Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie - Google Patents

Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie

Info

Publication number
ATE298004T1
ATE298004T1 AT00940234T AT00940234T ATE298004T1 AT E298004 T1 ATE298004 T1 AT E298004T1 AT 00940234 T AT00940234 T AT 00940234T AT 00940234 T AT00940234 T AT 00940234T AT E298004 T1 ATE298004 T1 AT E298004T1
Authority
AT
Austria
Prior art keywords
sequencing
diagnostic
areas
combination
nucleic acid
Prior art date
Application number
AT00940234T
Other languages
English (en)
Inventor
Marc Zabeau
Patrick Stanssens
Original Assignee
Methexis Genomics N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methexis Genomics N V filed Critical Methexis Genomics N V
Application granted granted Critical
Publication of ATE298004T1 publication Critical patent/ATE298004T1/de

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT00940234T 1999-04-30 2000-04-30 Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie ATE298004T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13198499P 1999-04-30 1999-04-30
PCT/EP2000/003904 WO2000066771A2 (en) 1999-04-30 2000-04-30 Diagnostic sequencing by a combination of specific cleavage and mass spectrometry

Publications (1)

Publication Number Publication Date
ATE298004T1 true ATE298004T1 (de) 2005-07-15

Family

ID=22451891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00940234T ATE298004T1 (de) 1999-04-30 2000-04-30 Diagnostische sequenzierung durch eine kombination von spezifischer spaltung und massenspektrometrie

Country Status (9)

Country Link
EP (1) EP1173622B1 (de)
JP (2) JP5615997B2 (de)
AT (1) ATE298004T1 (de)
AU (1) AU779112B2 (de)
CA (1) CA2370872C (de)
DE (1) DE60020830T2 (de)
IL (1) IL145607A0 (de)
NO (1) NO20015293L (de)
WO (1) WO2000066771A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7668658B2 (en) 1999-10-13 2010-02-23 Sequenom, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
AT410983B (de) 2001-09-14 2003-09-25 Huber Christian G Dr Verfahren zur ermittlung der sequenz von nukleinsäuren
JP4151317B2 (ja) 2002-06-07 2008-09-17 日本電気株式会社 プロテオーム解析方法、プロテオーム解析システム、およびプロテオーム解析プログラム
AU2003298733B2 (en) * 2002-11-27 2009-06-18 Agena Bioscience, Inc. Fragmentation-based methods and systems for sequence variation detection and discovery
US7584058B2 (en) * 2003-02-27 2009-09-01 Methexis Genomics N.V. Genetic diagnosis using multiple sequence variant analysis
WO2005024068A2 (en) * 2003-09-05 2005-03-17 Sequenom, Inc. Allele-specific sequence variation analysis
CA2561381C (en) 2004-03-26 2015-05-12 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US7608394B2 (en) 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
CA2562557A1 (en) 2004-04-09 2005-10-27 The Trustees Of Boston University Method for de novo detection of sequences in nucleic acids:target sequencing by fragmentation
US7785843B2 (en) 2004-06-23 2010-08-31 Sequenom, Inc. Target-specific compomers and methods of use
ES2494840T3 (es) 2005-03-15 2014-09-16 Fujirebio Europe N.V. Variantes víricas de la hepatitis B con susceptibilidad reducida a análogos de nucleósidos y usos de las mismas
EP1762629B1 (de) 2005-09-12 2009-11-11 Roche Diagnostics GmbH Nachweis biologischer DNA
EP2527474A1 (de) 2006-10-20 2012-11-28 Innogenetics N.V. Verfahren zur Analyse von Sequenzvariationen innerhalb des HCV-NS3/4A-Genombereichs
US10150990B2 (en) * 2008-04-21 2018-12-11 Roche Molecular Systems, Inc. Ribonucleotide tag nucleic acid detection
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
ES2577017T3 (es) 2009-12-22 2016-07-12 Sequenom, Inc. Procedimientos y kits para identificar la aneuploidia
EP2820129A1 (de) 2012-03-02 2015-01-07 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US20140093873A1 (en) 2012-07-13 2014-04-03 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US11060145B2 (en) 2013-03-13 2021-07-13 Sequenom, Inc. Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
EP3736344A1 (de) 2014-03-13 2020-11-11 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
WO2020145754A1 (ko) * 2019-01-11 2020-07-16 주식회사 진캐스트 유전자 변이 특이성이 증가된 dna 중합효소를 이용한 질량분석법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288644A (en) * 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
US5436143A (en) * 1992-12-23 1995-07-25 Hyman; Edward D. Method for enzymatic synthesis of oligonucleotides
CA2159081C (en) * 1993-03-24 2000-11-21 David Mead Dinucleotide restriction endonuclease preparations and methods of use
JP3637572B2 (ja) * 1995-03-27 2005-04-13 旭化成ファーマ株式会社 酵素による核酸の定量方法および定量用組成物
US5869242A (en) * 1995-09-18 1999-02-09 Myriad Genetics, Inc. Mass spectrometry to assess DNA sequence polymorphisms
AU2069597A (en) * 1996-03-04 1997-09-22 Genetrace Systems, Inc. Methods of screening nucleic acids using mass spectrometry
EP1164203B1 (de) * 1996-11-06 2007-10-10 Sequenom, Inc. DNA-Diagnostik mittels Massenspektrometrie
US6994960B1 (en) * 1997-05-28 2006-02-07 The Walter And Eliza Hall Institute Of Medical Research Nucleic acid diagnostics based on mass spectrometry or mass separation and base specific cleavage

Also Published As

Publication number Publication date
WO2000066771A3 (en) 2001-02-08
JP2002542838A (ja) 2002-12-17
EP1173622A2 (de) 2002-01-23
NO20015293D0 (no) 2001-10-29
IL145607A0 (en) 2002-06-30
AU5523600A (en) 2000-11-17
AU779112B2 (en) 2005-01-06
NO20015293L (no) 2001-12-20
JP2014221072A (ja) 2014-11-27
JP5615997B2 (ja) 2014-10-29
DE60020830T2 (de) 2006-07-27
DE60020830D1 (de) 2005-07-21
CA2370872C (en) 2007-02-06
EP1173622B1 (de) 2005-06-15
CA2370872A1 (en) 2000-11-09
WO2000066771A2 (en) 2000-11-09

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