ATE298336T1 - Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte - Google Patents
Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukteInfo
- Publication number
- ATE298336T1 ATE298336T1 AT01931561T AT01931561T ATE298336T1 AT E298336 T1 ATE298336 T1 AT E298336T1 AT 01931561 T AT01931561 T AT 01931561T AT 01931561 T AT01931561 T AT 01931561T AT E298336 T1 ATE298336 T1 AT E298336T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- intermediate products
- thiazolidinedione derivatives
- producing
- compounds
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001467 thiazolidinediones Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000007265 chloromethylation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00108303 | 2000-04-14 | ||
| PCT/EP2001/003802 WO2001079202A1 (en) | 2000-04-14 | 2001-04-04 | Processes for the preparation of thiazolidinedione derivatives and intermediates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE298336T1 true ATE298336T1 (de) | 2005-07-15 |
Family
ID=8168486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01931561T ATE298336T1 (de) | 2000-04-14 | 2001-04-04 | Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US6531609B2 (de) |
| EP (1) | EP1282619B1 (de) |
| JP (1) | JP2003531146A (de) |
| KR (1) | KR100519132B1 (de) |
| CN (1) | CN1231482C (de) |
| AT (1) | ATE298336T1 (de) |
| AU (1) | AU2001258306A1 (de) |
| CA (1) | CA2402374A1 (de) |
| DE (1) | DE60111634T2 (de) |
| DK (1) | DK1282619T3 (de) |
| ES (1) | ES2243493T3 (de) |
| JO (1) | JO2240B1 (de) |
| MX (1) | MXPA02010022A (de) |
| WO (1) | WO2001079202A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002080913A1 (en) * | 2001-04-06 | 2002-10-17 | F. Hoffmann-La Roche Ag | Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth |
| US7361711B2 (en) * | 2001-09-13 | 2008-04-22 | Acushnet Company | Compositions for use in golf balls |
| MXPA05013732A (es) * | 2003-06-26 | 2006-03-08 | Hoffmann La Roche | Proceso para preparacion de sensibilizador de insulina y compuesto intermediario del mismo. |
| BRPI0412236A (pt) | 2003-07-02 | 2006-09-12 | Hoffmann La Roche | compostos, processo para a sua manufatura, composições farmacêuticas que compreendem os mesmos, método para o tratamento e/ou prevenção de enfermidades que são moduladas por agonistas ppar(delta) e/ou ppar(alfa), e utilização desses compostos |
| CN102746290B (zh) * | 2012-06-21 | 2014-08-27 | 成都苑东药业有限公司 | 一种噻唑类化合物及其制备方法 |
| AU2023301282A1 (en) * | 2022-06-27 | 2025-01-09 | Trioar, Inc. | Compound comprising self-immolative group and ligand-drug conjugate comprising same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1249278B (de) | 1962-06-09 | 1967-09-07 | Monsanto Chemicals Limited Lon don | Verfahren zur Kernarvlierung aromati scher oder heteroaromatischer Verbindungen |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| DE4317320A1 (de) | 1993-05-25 | 1994-12-01 | Boehringer Mannheim Gmbh | Neue Thiazolidindione und diese enthaltende Arzneimittel |
| US5475170A (en) | 1994-06-27 | 1995-12-12 | Albermarle Corporation | Haloalkylation process |
| DE19711616A1 (de) | 1997-03-20 | 1998-09-24 | Boehringer Mannheim Gmbh | Verbessertes Verfahren zur Herstellung von Thiazolidindionen |
| DE19711617A1 (de) | 1997-03-20 | 1998-09-24 | Boehringer Mannheim Gmbh | Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DK1078923T3 (da) | 1999-08-02 | 2006-07-10 | Hoffmann La Roche | Fremgangsmåde til fremstilling af benzothiophenderivater |
| DE10241042B4 (de) | 2002-08-12 | 2006-04-13 | Manfred Rennings | Infobox |
-
2001
- 2001-03-22 US US09/814,907 patent/US6531609B2/en not_active Expired - Fee Related
- 2001-04-04 EP EP01931561A patent/EP1282619B1/de not_active Expired - Lifetime
- 2001-04-04 DK DK01931561T patent/DK1282619T3/da active
- 2001-04-04 CN CNB018079156A patent/CN1231482C/zh not_active Expired - Fee Related
- 2001-04-04 ES ES01931561T patent/ES2243493T3/es not_active Expired - Lifetime
- 2001-04-04 WO PCT/EP2001/003802 patent/WO2001079202A1/en not_active Ceased
- 2001-04-04 KR KR10-2002-7013637A patent/KR100519132B1/ko not_active Expired - Fee Related
- 2001-04-04 JP JP2001576801A patent/JP2003531146A/ja not_active Ceased
- 2001-04-04 AT AT01931561T patent/ATE298336T1/de not_active IP Right Cessation
- 2001-04-04 MX MXPA02010022A patent/MXPA02010022A/es active IP Right Grant
- 2001-04-04 AU AU2001258306A patent/AU2001258306A1/en not_active Abandoned
- 2001-04-04 DE DE60111634T patent/DE60111634T2/de not_active Expired - Fee Related
- 2001-04-04 CA CA002402374A patent/CA2402374A1/en not_active Abandoned
- 2001-04-08 JO JO200140A patent/JO2240B1/en active
-
2002
- 2002-11-05 US US10/288,316 patent/US6620941B2/en not_active Expired - Fee Related
-
2003
- 2003-08-05 US US10/634,395 patent/US6753432B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6531609B2 (en) | 2003-03-11 |
| ES2243493T3 (es) | 2005-12-01 |
| JO2240B1 (en) | 2004-10-07 |
| KR20020087136A (ko) | 2002-11-21 |
| WO2001079202A1 (en) | 2001-10-25 |
| US20030092916A1 (en) | 2003-05-15 |
| US20010049445A1 (en) | 2001-12-06 |
| MXPA02010022A (es) | 2003-02-12 |
| AU2001258306A1 (en) | 2001-10-30 |
| US20040024222A1 (en) | 2004-02-05 |
| US6753432B2 (en) | 2004-06-22 |
| DE60111634D1 (de) | 2005-07-28 |
| EP1282619A1 (de) | 2003-02-12 |
| CN1422267A (zh) | 2003-06-04 |
| DK1282619T3 (da) | 2005-10-17 |
| JP2003531146A (ja) | 2003-10-21 |
| EP1282619B1 (de) | 2005-06-22 |
| CN1231482C (zh) | 2005-12-14 |
| US6620941B2 (en) | 2003-09-16 |
| KR100519132B1 (ko) | 2005-10-04 |
| CA2402374A1 (en) | 2001-10-25 |
| DE60111634T2 (de) | 2006-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1282619 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |