ATE298336T1 - Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte - Google Patents

Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte

Info

Publication number
ATE298336T1
ATE298336T1 AT01931561T AT01931561T ATE298336T1 AT E298336 T1 ATE298336 T1 AT E298336T1 AT 01931561 T AT01931561 T AT 01931561T AT 01931561 T AT01931561 T AT 01931561T AT E298336 T1 ATE298336 T1 AT E298336T1
Authority
AT
Austria
Prior art keywords
formula
intermediate products
thiazolidinedione derivatives
producing
compounds
Prior art date
Application number
AT01931561T
Other languages
English (en)
Inventor
Michelangelo Scalone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE298336T1 publication Critical patent/ATE298336T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT01931561T 2000-04-14 2001-04-04 Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte ATE298336T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00108303 2000-04-14
PCT/EP2001/003802 WO2001079202A1 (en) 2000-04-14 2001-04-04 Processes for the preparation of thiazolidinedione derivatives and intermediates

Publications (1)

Publication Number Publication Date
ATE298336T1 true ATE298336T1 (de) 2005-07-15

Family

ID=8168486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931561T ATE298336T1 (de) 2000-04-14 2001-04-04 Verfahren zur herstellung von thiazolidinedion- derivaten und zwischenprodukte

Country Status (14)

Country Link
US (3) US6531609B2 (de)
EP (1) EP1282619B1 (de)
JP (1) JP2003531146A (de)
KR (1) KR100519132B1 (de)
CN (1) CN1231482C (de)
AT (1) ATE298336T1 (de)
AU (1) AU2001258306A1 (de)
CA (1) CA2402374A1 (de)
DE (1) DE60111634T2 (de)
DK (1) DK1282619T3 (de)
ES (1) ES2243493T3 (de)
JO (1) JO2240B1 (de)
MX (1) MXPA02010022A (de)
WO (1) WO2001079202A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004525168A (ja) * 2001-04-06 2004-08-19 エフ．ホフマン−ラ　ロシュ　アーゲー 腫瘍の成長を抑制もしくは減少するための単独または他の治療薬との組合わせでのチアゾリジンジオン
US7361711B2 (en) * 2001-09-13 2008-04-22 Acushnet Company Compositions for use in golf balls
JP2007506671A (ja) * 2003-06-26 2007-03-22 エフ．ホフマン−ラ　ロシュ　アーゲー インスリン抵抗性改善薬を製造する方法およびその中間体化合物
KR100796093B1 (ko) 2003-07-02 2008-01-21 에프. 호프만-라 로슈 아게 티아졸 고리로 치환된 인돌릴 유도체 및 ｐｐａｒ조절제로서 그의 용도
CN102746290B (zh) * 2012-06-21 2014-08-27 成都苑东药业有限公司 一种噻唑类化合物及其制备方法
JP2025525296A (ja) * 2022-06-27 2025-08-05 トライオール インコーポレイテッド 自壊性基を含む化合物及びそれを含むリガンド－薬物コンジュゲート

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249278B (de) 1962-06-09 1967-09-07 Monsanto Chemicals Limited Lon don Verfahren zur Kernarvlierung aromati scher oder heteroaromatischer Verbindungen
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物，其制备方法和用途
DE4317320A1 (de) 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
US5475170A (en) 1994-06-27 1995-12-12 Albermarle Corporation Haloalkylation process
DE19711616A1 (de) * 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
DE19711617A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
ES2258431T3 (es) 1999-08-02 2006-09-01 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de benzotiofeno.
DE10241042B4 (de) 2002-08-12 2006-04-13 Manfred Rennings Infobox

Also Published As

Publication number Publication date
CN1231482C (zh) 2005-12-14
CA2402374A1 (en) 2001-10-25
US20010049445A1 (en) 2001-12-06
EP1282619B1 (de) 2005-06-22
MXPA02010022A (es) 2003-02-12
WO2001079202A1 (en) 2001-10-25
US20030092916A1 (en) 2003-05-15
US6531609B2 (en) 2003-03-11
DK1282619T3 (da) 2005-10-17
EP1282619A1 (de) 2003-02-12
DE60111634T2 (de) 2006-05-18
US6620941B2 (en) 2003-09-16
US6753432B2 (en) 2004-06-22
KR20020087136A (ko) 2002-11-21
ES2243493T3 (es) 2005-12-01
KR100519132B1 (ko) 2005-10-04
AU2001258306A1 (en) 2001-10-30
JO2240B1 (en) 2004-10-07
JP2003531146A (ja) 2003-10-21
US20040024222A1 (en) 2004-02-05
CN1422267A (zh) 2003-06-04
DE60111634D1 (de) 2005-07-28

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