ATE298420T1 - Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung - Google Patents
Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellungInfo
- Publication number
- ATE298420T1 ATE298420T1 AT97928393T AT97928393T ATE298420T1 AT E298420 T1 ATE298420 T1 AT E298420T1 AT 97928393 T AT97928393 T AT 97928393T AT 97928393 T AT97928393 T AT 97928393T AT E298420 T1 ATE298420 T1 AT E298420T1
- Authority
- AT
- Austria
- Prior art keywords
- sensor
- layer
- sample solution
- electrode membrane
- enzyme
- Prior art date
Links
- 108090000790 Enzymes Proteins 0.000 title abstract 5
- 102000004190 Enzymes Human genes 0.000 title abstract 5
- 239000012528 membrane Substances 0.000 title abstract 4
- 239000012488 sample solution Substances 0.000 abstract 3
- 239000012491 analyte Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 108010093096 Immobilized Enzymes Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 229920005596 polymer binder Polymers 0.000 abstract 1
- 239000002491 polymer binding agent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/002—Electrode membranes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/817—Enzyme or microbe electrode
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Inert Electrodes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/679,089 US5696314A (en) | 1996-07-12 | 1996-07-12 | Multilayer enzyme electrode membranes and methods of making same |
| PCT/IB1997/000861 WO1998002736A1 (en) | 1996-07-12 | 1997-07-11 | Multilayer enzyme electrode membranes and methods of making same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE298420T1 true ATE298420T1 (de) | 2005-07-15 |
Family
ID=24725520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97928393T ATE298420T1 (de) | 1996-07-12 | 1997-07-11 | Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5696314A (de) |
| EP (1) | EP0910794B1 (de) |
| JP (1) | JP2001506742A (de) |
| AT (1) | ATE298420T1 (de) |
| AU (1) | AU3270797A (de) |
| DE (1) | DE69733608T2 (de) |
| DK (1) | DK0910794T3 (de) |
| ES (1) | ES2245000T3 (de) |
| WO (1) | WO1998002736A1 (de) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593852A (en) * | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
| US7899511B2 (en) | 2004-07-13 | 2011-03-01 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US6030827A (en) * | 1998-01-23 | 2000-02-29 | I-Stat Corporation | Microfabricated aperture-based sensor |
| US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6280587B1 (en) * | 1998-07-02 | 2001-08-28 | Nec Corporation | Enzyme electrode and a biosensor and a measuring apparatus therewith |
| EP1039291A1 (de) * | 1999-03-26 | 2000-09-27 | Sony International (Europe) GmbH | Optochemischer Fühler and Herstellungsmethode |
| AU2001263022A1 (en) * | 2000-05-12 | 2001-11-26 | Therasense, Inc. | Electrodes with multilayer membranes and methods of using and making the electrodes |
| ATE278956T1 (de) * | 2000-07-27 | 2004-10-15 | Micronas Holding Gmbh | Sensor-chips mit polysiloxan-mehrfachschichten |
| EP1336839B1 (de) * | 2000-10-27 | 2012-01-25 | ARKRAY, Inc. | Biosensor |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US6932894B2 (en) * | 2001-05-15 | 2005-08-23 | Therasense, Inc. | Biosensor membranes composed of polymers containing heterocyclic nitrogens |
| DE10296998T5 (de) * | 2001-07-24 | 2004-05-27 | Nec Corp. | Enzymelektrode und Verfahren zum Herstellen derselben |
| US6671554B2 (en) | 2001-09-07 | 2003-12-30 | Medtronic Minimed, Inc. | Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same |
| US8506550B2 (en) * | 2001-09-07 | 2013-08-13 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
| US6915147B2 (en) | 2001-09-07 | 2005-07-05 | Medtronic Minimed, Inc. | Sensing apparatus and process |
| US7025760B2 (en) * | 2001-09-07 | 2006-04-11 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
| US7323142B2 (en) * | 2001-09-07 | 2008-01-29 | Medtronic Minimed, Inc. | Sensor substrate and method of fabricating same |
| US6809507B2 (en) | 2001-10-23 | 2004-10-26 | Medtronic Minimed, Inc. | Implantable sensor electrodes and electronic circuitry |
| US7192766B2 (en) | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
| US8465466B2 (en) | 2001-10-23 | 2013-06-18 | Medtronic Minimed, Inc | Method and system for non-vascular sensor implantation |
| US20040137547A1 (en) * | 2001-12-28 | 2004-07-15 | Medtronic Minimed, Inc. | Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property |
| US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US20070227907A1 (en) * | 2006-04-04 | 2007-10-04 | Rajiv Shah | Methods and materials for controlling the electrochemistry of analyte sensors |
| US7162289B2 (en) * | 2002-09-27 | 2007-01-09 | Medtronic Minimed, Inc. | Method and apparatus for enhancing the integrity of an implantable sensor device |
| US7736309B2 (en) * | 2002-09-27 | 2010-06-15 | Medtronic Minimed, Inc. | Implantable sensor method and system |
| US20050272989A1 (en) * | 2004-06-04 | 2005-12-08 | Medtronic Minimed, Inc. | Analyte sensors and methods for making and using them |
| US20040074785A1 (en) * | 2002-10-18 | 2004-04-22 | Holker James D. | Analyte sensors and methods for making them |
| US9237865B2 (en) * | 2002-10-18 | 2016-01-19 | Medtronic Minimed, Inc. | Analyte sensors and methods for making and using them |
| US7519408B2 (en) | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| ATE464834T1 (de) * | 2003-09-30 | 2010-05-15 | Hoffmann La Roche | Sensor mit verbesserter biokompatibilität |
| US8414489B2 (en) * | 2003-11-13 | 2013-04-09 | Medtronic Minimed, Inc. | Fabrication of multi-sensor arrays |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| WO2005057168A2 (en) | 2003-12-05 | 2005-06-23 | Dexcom, Inc. | Calibration techniques for a continuous analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| RU2004103056A (ru) * | 2004-02-05 | 2005-07-10 | Сергей Владимирович Синицын (BY) | Способ воздействия на молекулу, способ управления ферментативным катализом и устройство захвата и изменения молекулы |
| US7807043B2 (en) * | 2004-02-23 | 2010-10-05 | Oakville Hong Kong Company Limited | Microfluidic test device |
| WO2009048462A1 (en) | 2007-10-09 | 2009-04-16 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US20050266571A1 (en) * | 2004-03-26 | 2005-12-01 | Phil Stout | Method for feedback control of a microfluidic system |
| US20060013731A1 (en) * | 2004-03-26 | 2006-01-19 | Phil Stout | Microfluidic system with feedback control |
| US8792955B2 (en) | 2004-05-03 | 2014-07-29 | Dexcom, Inc. | Transcutaneous analyte sensor |
| EP1751530A2 (de) * | 2004-05-24 | 2007-02-14 | Albatros Technologies GmbH & Co. KG | Vorrichtung, system und verfahren für analytmessungen |
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US8989833B2 (en) | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7905833B2 (en) | 2004-07-13 | 2011-03-15 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
| CN101076601B (zh) * | 2004-12-13 | 2013-11-13 | 拜尔保健有限公司 | 用于测量生物液体中的分析物的自我限定大小的组合物和检验设备 |
| US7923400B2 (en) * | 2004-12-14 | 2011-04-12 | Nissan Motor Co., Ltd. | Method of making an electrode for use in a battery |
| US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
| US20060249542A1 (en) * | 2005-04-26 | 2006-11-09 | Allen Randall E | Dispensing device for materials, method and system of use thereof |
| US7725148B2 (en) | 2005-09-23 | 2010-05-25 | Medtronic Minimed, Inc. | Sensor with layered electrodes |
| US9757061B2 (en) | 2006-01-17 | 2017-09-12 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US20080306444A1 (en) | 2007-06-08 | 2008-12-11 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US8700114B2 (en) | 2008-07-31 | 2014-04-15 | Medtronic Minmed, Inc. | Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them |
| US20100025238A1 (en) * | 2008-07-31 | 2010-02-04 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
| WO2010027771A1 (en) | 2008-08-27 | 2010-03-11 | Edwards Lifesciences Corporation | Analyte sensor |
| US8660628B2 (en) * | 2009-12-21 | 2014-02-25 | Medtronic Minimed, Inc. | Analyte sensors comprising blended membrane compositions and methods for making and using them |
| HK1217364A1 (zh) * | 2013-01-11 | 2017-01-06 | Northeastern University | 唾液葡萄糖監測系統 |
| EP3380833B1 (de) * | 2015-11-27 | 2019-12-25 | Radiometer Medical ApS | Aussenschicht für enzymsensoren |
| ES2974312T3 (es) | 2016-03-04 | 2024-06-26 | Abbott Diabetes Care Inc | Enzimas sensibles dependientes de NAD(P), electrodos y sensores y procedimientos para la fabricación y utilización de los mismos |
| CA3055183C (en) * | 2017-03-03 | 2021-11-30 | Siemens Healthcare Diagnostics Inc. | Nanobead containing biosensors and methods of production and use thereof |
| US11382540B2 (en) | 2017-10-24 | 2022-07-12 | Dexcom, Inc. | Pre-connected analyte sensors |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| US11109784B2 (en) * | 2018-04-09 | 2021-09-07 | California Institute Of Technology | Metal-enzyme sandwich layers |
| EP4663121A1 (de) * | 2019-01-28 | 2025-12-17 | Abbott Diabetes Care Inc. | Analytsensoren mit mehreren enzymen |
| DK3917396T3 (da) | 2019-01-28 | 2024-12-02 | Abbott Diabetes Care Inc | Analytsensorer, der er forsynet med dualdetektering af glukose og ketoner |
| EP4552565A1 (de) | 2019-01-28 | 2025-05-14 | Abbott Diabetes Care, Inc. | Analytsensoren und messverfahren für den doppelnachweis von glucose und ethanol |
| WO2021138473A1 (en) | 2020-01-03 | 2021-07-08 | Abbott Diabetes Care Inc. | Sensor array systems and methods for detecting multiple analytes |
| CN114660140B (zh) * | 2020-12-23 | 2024-02-23 | 北京京东方技术开发有限公司 | 生物检测装置、生物芯片、微电极结构及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661011A (en) * | 1970-03-02 | 1972-05-09 | Melabs Inc | High-speed microvolume membrane osmometry |
| US3635075A (en) * | 1970-06-29 | 1972-01-18 | Beckman Instruments Inc | Osmometer |
| US3756923A (en) * | 1970-11-30 | 1973-09-04 | H Dahms | Method of determining so2 concentration |
| US4238757A (en) * | 1976-03-19 | 1980-12-09 | General Electric Company | Field effect transistor for detection of biological reactions |
| US4267023A (en) * | 1977-10-17 | 1981-05-12 | Orion Research Incorporated | Chemically integrating dosimeter and gas analysis methods |
| US4311669A (en) * | 1980-08-21 | 1982-01-19 | The Bendix Corporation | Membrane interface for ion mobility detector cells |
| JPS57208997A (en) * | 1981-06-17 | 1982-12-22 | Fuji Photo Film Co Ltd | Liquid analyzing material for oxidase enzyme reaction system |
| JPS61281960A (ja) * | 1985-06-07 | 1986-12-12 | Kirin Brewery Co Ltd | ハイブリッド酵素膜アルコ−ルセンサ− |
| GB8612861D0 (en) * | 1986-05-27 | 1986-07-02 | Cambridge Life Sciences | Immobilised enzyme biosensors |
| GB8817997D0 (en) * | 1988-07-28 | 1988-09-01 | Cambridge Life Sciences | Enzyme electrodes & improvements in manufacture thereof |
| US5438984A (en) * | 1988-09-08 | 1995-08-08 | Sudor Partners | Apparatus and method for the collection of analytes on a dermal patch |
| US5200051A (en) * | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5212050A (en) * | 1988-11-14 | 1993-05-18 | Mier Randall M | Method of forming a permselective layer |
| JPH04212050A (ja) * | 1990-05-29 | 1992-08-03 | Matsushita Electric Ind Co Ltd | バイオセンサおよびその製造法 |
| JP2786336B2 (ja) * | 1991-03-04 | 1998-08-13 | 富士写真フイルム株式会社 | 免疫分析要素および免疫分析方法 |
| WO1993013408A1 (en) * | 1991-12-31 | 1993-07-08 | Abbott Laboratories | Composite membrane |
| JP2550463B2 (ja) * | 1992-09-25 | 1996-11-06 | 株式会社エー・アンド・デイ | 酵素電極 |
| US5494562A (en) * | 1994-06-27 | 1996-02-27 | Ciba Corning Diagnostics Corp. | Electrochemical sensors |
| US5520788A (en) * | 1995-01-17 | 1996-05-28 | The Yellow Springs Instrument Company, Inc. | Support layer for enzyme electrode laminated membranes |
| EP0771867A3 (de) * | 1995-10-30 | 1998-09-02 | Ciba-Geigy Japan Limited | Enzymelektrode |
| EP0859954B1 (de) * | 1995-11-08 | 2005-06-01 | Hypoguard Limited | Biosensoren mit membran |
-
1996
- 1996-07-12 US US08/679,089 patent/US5696314A/en not_active Expired - Lifetime
-
1997
- 1997-07-11 DK DK97928393T patent/DK0910794T3/da active
- 1997-07-11 DE DE69733608T patent/DE69733608T2/de not_active Expired - Fee Related
- 1997-07-11 ES ES97928393T patent/ES2245000T3/es not_active Expired - Lifetime
- 1997-07-11 EP EP97928393A patent/EP0910794B1/de not_active Expired - Lifetime
- 1997-07-11 WO PCT/IB1997/000861 patent/WO1998002736A1/en not_active Ceased
- 1997-07-11 JP JP50579698A patent/JP2001506742A/ja not_active Withdrawn
- 1997-07-11 AU AU32707/97A patent/AU3270797A/en not_active Abandoned
- 1997-07-11 AT AT97928393T patent/ATE298420T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0910794B1 (de) | 2005-06-22 |
| WO1998002736A1 (en) | 1998-01-22 |
| US5696314A (en) | 1997-12-09 |
| DE69733608T2 (de) | 2006-05-11 |
| JP2001506742A (ja) | 2001-05-22 |
| AU3270797A (en) | 1998-02-09 |
| DK0910794T3 (da) | 2005-09-19 |
| EP0910794A1 (de) | 1999-04-28 |
| DE69733608D1 (de) | 2005-07-28 |
| ES2245000T3 (es) | 2005-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0910794 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |