DK0910794T3 - Flerlagsenzymelektrodemembraner og fremgangsmåder til fremstilling deraf - Google Patents

Flerlagsenzymelektrodemembraner og fremgangsmåder til fremstilling deraf

Info

Publication number
DK0910794T3
DK0910794T3 DK97928393T DK97928393T DK0910794T3 DK 0910794 T3 DK0910794 T3 DK 0910794T3 DK 97928393 T DK97928393 T DK 97928393T DK 97928393 T DK97928393 T DK 97928393T DK 0910794 T3 DK0910794 T3 DK 0910794T3
Authority
DK
Denmark
Prior art keywords
enzyme electrode
sensor
multilayer
sample solution
electrode membrane
Prior art date
Application number
DK97928393T
Other languages
English (en)
Inventor
Peter Edelman
Robert Mccaffrey
Bonnie Dalzell
Katarina Tkacik
Susan Holbert
Mark Boden
James Flaherty
Michael Flanagan
Josef Brown
Kimiya Takeshita
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0910794T3 publication Critical patent/DK0910794T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Inert Electrodes (AREA)
DK97928393T 1996-07-12 1997-07-11 Flerlagsenzymelektrodemembraner og fremgangsmåder til fremstilling deraf DK0910794T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/679,089 US5696314A (en) 1996-07-12 1996-07-12 Multilayer enzyme electrode membranes and methods of making same
PCT/IB1997/000861 WO1998002736A1 (en) 1996-07-12 1997-07-11 Multilayer enzyme electrode membranes and methods of making same

Publications (1)

Publication Number Publication Date
DK0910794T3 true DK0910794T3 (da) 2005-09-19

Family

ID=24725520

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97928393T DK0910794T3 (da) 1996-07-12 1997-07-11 Flerlagsenzymelektrodemembraner og fremgangsmåder til fremstilling deraf

Country Status (9)

Country Link
US (1) US5696314A (da)
EP (1) EP0910794B1 (da)
JP (1) JP2001506742A (da)
AT (1) ATE298420T1 (da)
AU (1) AU3270797A (da)
DE (1) DE69733608T2 (da)
DK (1) DK0910794T3 (da)
ES (1) ES2245000T3 (da)
WO (1) WO1998002736A1 (da)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6030827A (en) * 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
EP0969282B1 (en) * 1998-07-02 2011-09-21 NEC Corporation An enzyme electrode and a biosensor and a measuring apparatus therewith
EP1039291A1 (en) * 1999-03-26 2000-09-27 Sony International (Europe) GmbH Optochemical sensor and method for its construction
WO2001088524A1 (en) 2000-05-12 2001-11-22 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
DE50008123D1 (de) * 2000-07-27 2004-11-11 Micronas Holding Gmbh Sensor-Chips mit Polysiloxan-Mehrfachschichten
EP1336839B1 (en) * 2000-10-27 2012-01-25 ARKRAY, Inc. Biosensor
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6932894B2 (en) * 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
WO2003010529A1 (fr) * 2001-07-24 2003-02-06 Nec Corporation Electrode a enzyme et son procede de production
US6915147B2 (en) 2001-09-07 2005-07-05 Medtronic Minimed, Inc. Sensing apparatus and process
US8506550B2 (en) * 2001-09-07 2013-08-13 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US7323142B2 (en) * 2001-09-07 2008-01-29 Medtronic Minimed, Inc. Sensor substrate and method of fabricating same
US7025760B2 (en) * 2001-09-07 2006-04-11 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US6671554B2 (en) 2001-09-07 2003-12-30 Medtronic Minimed, Inc. Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same
US7192766B2 (en) * 2001-10-23 2007-03-20 Medtronic Minimed, Inc. Sensor containing molded solidified protein
US6809507B2 (en) * 2001-10-23 2004-10-26 Medtronic Minimed, Inc. Implantable sensor electrodes and electronic circuitry
US8465466B2 (en) 2001-10-23 2013-06-18 Medtronic Minimed, Inc Method and system for non-vascular sensor implantation
US20040137547A1 (en) * 2001-12-28 2004-07-15 Medtronic Minimed, Inc. Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US20070227907A1 (en) * 2006-04-04 2007-10-04 Rajiv Shah Methods and materials for controlling the electrochemistry of analyte sensors
US7736309B2 (en) * 2002-09-27 2010-06-15 Medtronic Minimed, Inc. Implantable sensor method and system
US7162289B2 (en) * 2002-09-27 2007-01-09 Medtronic Minimed, Inc. Method and apparatus for enhancing the integrity of an implantable sensor device
US20050272989A1 (en) * 2004-06-04 2005-12-08 Medtronic Minimed, Inc. Analyte sensors and methods for making and using them
US20040074785A1 (en) * 2002-10-18 2004-04-22 Holker James D. Analyte sensors and methods for making them
US9237865B2 (en) * 2002-10-18 2016-01-19 Medtronic Minimed, Inc. Analyte sensors and methods for making and using them
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7494465B2 (en) 2004-07-13 2009-02-24 Dexcom, Inc. Transcutaneous analyte sensor
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
JP2007514460A (ja) * 2003-09-30 2007-06-07 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 増大した生物適合性を示すセンサー
US8414489B2 (en) * 2003-11-13 2013-04-09 Medtronic Minimed, Inc. Fabrication of multi-sensor arrays
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
ATE480761T1 (de) 2003-12-05 2010-09-15 Dexcom Inc Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
RU2004103056A (ru) * 2004-02-05 2005-07-10 Сергей Владимирович Синицын (BY) Способ воздействия на молекулу, способ управления ферментативным катализом и устройство захвата и изменения молекулы
US7807043B2 (en) * 2004-02-23 2010-10-05 Oakville Hong Kong Company Limited Microfluidic test device
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20050266571A1 (en) * 2004-03-26 2005-12-01 Phil Stout Method for feedback control of a microfluidic system
US20060013731A1 (en) * 2004-03-26 2006-01-19 Phil Stout Microfluidic system with feedback control
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
WO2005121759A2 (en) * 2004-05-24 2005-12-22 Albatros Technologies Gmbh & Co. Kg Device and method for analyte measurement
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US8989833B2 (en) 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US8886272B2 (en) 2004-07-13 2014-11-11 Dexcom, Inc. Analyte sensor
US7964372B2 (en) * 2004-12-13 2011-06-21 Bayer Healthcare Llc Size self-limiting compositions and test devices for measuring analytes in biological fluids
US7923400B2 (en) * 2004-12-14 2011-04-12 Nissan Motor Co., Ltd. Method of making an electrode for use in a battery
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20060249542A1 (en) * 2005-04-26 2006-11-09 Allen Randall E Dispensing device for materials, method and system of use thereof
US7725148B2 (en) 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
CA2688184A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP4159114B1 (en) 2007-10-09 2024-04-10 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US20100025238A1 (en) * 2008-07-31 2010-02-04 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US8700114B2 (en) * 2008-07-31 2014-04-15 Medtronic Minmed, Inc. Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them
WO2010027771A1 (en) 2008-08-27 2010-03-11 Edwards Lifesciences Corporation Analyte sensor
US8660628B2 (en) * 2009-12-21 2014-02-25 Medtronic Minimed, Inc. Analyte sensors comprising blended membrane compositions and methods for making and using them
EP2943784A4 (en) * 2013-01-11 2016-12-14 Univ Northeastern Saliva glucose monitoring system
US11629368B2 (en) * 2015-11-27 2023-04-18 Radiometer Medical Aps Outer layer for enzyme sensors
DK3423591T3 (da) 2016-03-04 2024-01-29 Abbott Diabetes Care Inc NAD(P)-afhængige sensitive enzymer, elektroder og sensorer og fremgangsmåder til fremstilling og anvendelse deraf
CA3055183C (en) * 2017-03-03 2021-11-30 Siemens Healthcare Diagnostics Inc. Nanobead containing biosensors and methods of production and use thereof
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
DK3928687T3 (da) 2017-10-24 2024-09-30 Dexcom Inc Bærbar indretning med på forhånd forbundet analytsensor
US11109784B2 (en) * 2018-04-09 2021-09-07 California Institute Of Technology Metal-enzyme sandwich layers
CN113453620B (zh) 2019-01-28 2024-03-05 美国雅培糖尿病护理公司 用于双重检测葡萄糖和乙醇的分析物传感器和感测方法
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
CA3126240A1 (en) * 2019-01-28 2020-08-06 Abbott Diabetes Cares Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN115038381A (zh) 2020-01-03 2022-09-09 美国雅培糖尿病护理公司 用于检测多种分析物的传感器阵列系统和方法
CN114660140B (zh) * 2020-12-23 2024-02-23 北京京东方技术开发有限公司 生物检测装置、生物芯片、微电极结构及其制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661011A (en) * 1970-03-02 1972-05-09 Melabs Inc High-speed microvolume membrane osmometry
US3635075A (en) * 1970-06-29 1972-01-18 Beckman Instruments Inc Osmometer
US3756923A (en) * 1970-11-30 1973-09-04 H Dahms Method of determining so2 concentration
US4238757A (en) * 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
US4267023A (en) * 1977-10-17 1981-05-12 Orion Research Incorporated Chemically integrating dosimeter and gas analysis methods
US4311669A (en) * 1980-08-21 1982-01-19 The Bendix Corporation Membrane interface for ion mobility detector cells
JPS57208997A (en) * 1981-06-17 1982-12-22 Fuji Photo Film Co Ltd Liquid analyzing material for oxidase enzyme reaction system
JPS61281960A (ja) * 1985-06-07 1986-12-12 Kirin Brewery Co Ltd ハイブリッド酵素膜アルコ−ルセンサ−
GB8612861D0 (en) * 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
GB8817997D0 (en) * 1988-07-28 1988-09-01 Cambridge Life Sciences Enzyme electrodes & improvements in manufacture thereof
US5438984A (en) * 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5212050A (en) * 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
JPH04212050A (ja) * 1990-05-29 1992-08-03 Matsushita Electric Ind Co Ltd バイオセンサおよびその製造法
JP2786336B2 (ja) * 1991-03-04 1998-08-13 富士写真フイルム株式会社 免疫分析要素および免疫分析方法
AU3274693A (en) * 1991-12-31 1993-07-28 Abbott Laboratories Composite membrane
JP2550463B2 (ja) * 1992-09-25 1996-11-06 株式会社エー・アンド・デイ 酵素電極
US5494562A (en) * 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US5520788A (en) * 1995-01-17 1996-05-28 The Yellow Springs Instrument Company, Inc. Support layer for enzyme electrode laminated membranes
EP0771867A3 (en) * 1995-10-30 1998-09-02 Ciba-Geigy Japan Limited Enzyme electrode
DE69634802T2 (de) * 1995-11-08 2006-03-16 Hypoguard Ltd., Woodbridge Biosensoren mit membran

Also Published As

Publication number Publication date
ES2245000T3 (es) 2005-12-16
ATE298420T1 (de) 2005-07-15
DE69733608T2 (de) 2006-05-11
AU3270797A (en) 1998-02-09
EP0910794B1 (en) 2005-06-22
DE69733608D1 (de) 2005-07-28
WO1998002736A1 (en) 1998-01-22
JP2001506742A (ja) 2001-05-22
EP0910794A1 (en) 1999-04-28
US5696314A (en) 1997-12-09

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