ATE298562T1 - Hydrogelpartikel formulierungen - Google Patents

Hydrogelpartikel formulierungen

Info

Publication number
ATE298562T1
ATE298562T1 AT00901795T AT00901795T ATE298562T1 AT E298562 T1 ATE298562 T1 AT E298562T1 AT 00901795 T AT00901795 T AT 00901795T AT 00901795 T AT00901795 T AT 00901795T AT E298562 T1 ATE298562 T1 AT E298562T1
Authority
AT
Austria
Prior art keywords
methods
hydrogel particle
particle formulations
new compositions
compositions
Prior art date
Application number
AT00901795T
Other languages
English (en)
Inventor
Barbara H O'connor
Steven Joseph Prestrelski
Yuh-Fun Maa
Andrew Muddle
Roderick Hafner
Terry Lee Burkoth
Original Assignee
Powderject Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Res Ltd filed Critical Powderject Res Ltd
Application granted granted Critical
Publication of ATE298562T1 publication Critical patent/ATE298562T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00901795T 1999-02-03 2000-02-03 Hydrogelpartikel formulierungen ATE298562T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11833499P 1999-02-03 1999-02-03
PCT/GB2000/000349 WO2000045792A1 (en) 1999-02-03 2000-02-03 Hydrogel particle formulations

Publications (1)

Publication Number Publication Date
ATE298562T1 true ATE298562T1 (de) 2005-07-15

Family

ID=22377934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00901795T ATE298562T1 (de) 1999-02-03 2000-02-03 Hydrogelpartikel formulierungen

Country Status (16)

Country Link
US (1) US7022313B2 (de)
EP (1) EP1146861B1 (de)
JP (1) JP2002536317A (de)
KR (1) KR100845769B1 (de)
CN (1) CN1230152C (de)
AT (1) ATE298562T1 (de)
AU (1) AU780397B2 (de)
BR (1) BR0007974A (de)
CA (1) CA2361555A1 (de)
DE (1) DE60021059T2 (de)
ES (1) ES2243229T3 (de)
IL (2) IL144597A0 (de)
MX (1) MXPA01007844A (de)
NZ (1) NZ513538A (de)
PT (1) PT1146861E (de)
WO (1) WO2000045792A1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050214227A1 (en) * 1999-03-08 2005-09-29 Powderject Research Limited Microparticle formulations for sustained-release of bioactive compounds
JP2002538195A (ja) * 1999-03-08 2002-11-12 パウダージェクト リサーチ リミテッド 生物活性化合物の持続放出用の無針注射器を使用する微粒子製剤の送達
EP2295043A1 (de) 1999-10-29 2011-03-16 Euro-Celtique S.A. Hydrocodon-Formulierungen mit gesteuerter Freisetzung
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
WO2002019989A2 (en) * 2000-09-08 2002-03-14 Powderject Research Limited Alginate particle formulation
AU2002227383B2 (en) 2000-10-30 2004-07-08 Euro-Celtique S.A. Controlled release hydrocodone formulations
GB0103620D0 (en) * 2001-02-14 2001-03-28 Prometic Biosciences Ltd Sterile composition and its preparation
US7943067B2 (en) * 2001-08-16 2011-05-17 Polytechnic Institute Of New York University Nanogels and their production using liposomes as reactors
GB2379390B (en) * 2001-09-11 2005-01-26 Caretek Medical Ltd A novel drug delivery technology
BR0214280A (pt) * 2001-11-19 2005-01-11 Becton Dickinson Co Composição farmacêuticas em forma particulada
KR100675459B1 (ko) * 2002-04-10 2007-01-26 오브스체스트보 에스 오그라니체노이 오트베트스트벤노스츄 (비타겔) 다관능 생체적합 친수성 젤 및 그 제조방법
EP1356826A1 (de) * 2002-04-22 2003-10-29 BIOMAY Produktions- und Handels- Aktiengesellschaft Mikropartikel die Kohlenhydratkugeln enthalten an welche ein Allergen kovalent gebunden sind
GB0300008D0 (en) * 2003-01-02 2003-02-05 Optinose As Delivery devices
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1697035B1 (de) * 2003-12-22 2017-11-15 Warren H. Finlay Pulverbildung durch atmosphärische sprühgefriertrocknung
ITRM20040168A1 (it) * 2004-04-01 2004-07-01 Sigma Tau Ind Farmaceuti Composizione a rilascio modificato ph dipendente.
KR100624450B1 (ko) 2004-12-10 2006-09-18 삼성전자주식회사 히드로겔을 이용한 생물분자의 분리 및 정제 방법
KR100624452B1 (ko) 2004-12-21 2006-09-18 삼성전자주식회사 고정화된 히드로겔 또는 peg-히드로겔 공중합체를이용한 핵산의 분리 및 정제 방법
NZ543314A (en) * 2005-10-28 2007-08-31 Interag A delivery system where the driving substance contains the active component
US20070112592A1 (en) * 2005-11-17 2007-05-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Payments in providing assistance related to health
US10042980B2 (en) * 2005-11-17 2018-08-07 Gearbox Llc Providing assistance related to health
EP1981338A2 (de) * 2006-01-13 2008-10-22 Advanced Bionutrition Corporation Produktionssystem mit kontinuierlicher sprühnebelaufnahme
CA2648291A1 (en) * 2006-04-04 2007-11-01 Stc.Unm Swellable particles for drug delivery
US20080069891A1 (en) * 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
US8932634B2 (en) * 2006-06-15 2015-01-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Hydrocolloid carrier beads with inert filler material
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
JP2008096503A (ja) * 2006-10-06 2008-04-24 Toshiba Corp 粉末状感光性組成物の製造方法、感光性組成物およびこの感光性組成物から形成された光記録媒体
CN101861311A (zh) 2007-07-21 2010-10-13 阿尔巴尼分子研究公司 5-吡啶酮取代的吲唑
US8093038B2 (en) * 2007-09-17 2012-01-10 Illinois Institute Of Technology Apparatus and method for encapsulating pancreatic cells
WO2009049089A1 (en) * 2007-10-09 2009-04-16 Washington University In St. Louis Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
US9446150B2 (en) 2007-10-09 2016-09-20 Washington University Particles for imaging
US8293510B2 (en) * 2007-11-16 2012-10-23 University Of Kansas Method of preparing a hydrogel network encapsulating cells
CN103351390A (zh) 2007-11-21 2013-10-16 解码遗传Ehf公司 用于治疗肺部和心血管病症的联芳基pde4 抑制剂
CA2727055C (en) 2008-01-11 2016-12-20 Albany Molecular Research, Inc. (1-azinone) -substituted pyridoindoles as mch antagonists
WO2009108760A2 (en) 2008-02-26 2009-09-03 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
CN105944095B (zh) * 2008-03-05 2021-04-02 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法
WO2010059836A1 (en) 2008-11-20 2010-05-27 Decode Genetics Ehf Substituted aza-bridged bicyclics for cardiovascular and cns disease
WO2010084499A2 (en) 2009-01-26 2010-07-29 Israel Institute For Biological Research Bicyclic heterocyclic spiro compounds
EP2421952B1 (de) * 2009-04-20 2016-03-30 Galen Bio, Inc. Zusammensetzungen für die transfektion von biomolekülen in zellen
EP3960215B1 (de) 2009-12-15 2024-10-16 Incept, LLC Implantate und biologisch abbaubare bezugsmarkierungen
US9764043B2 (en) 2009-12-17 2017-09-19 Washington University Antithrombotic nanoparticle
US9808500B2 (en) 2009-12-17 2017-11-07 Washington University Antithrombotic nanoparticle
EP2525815B1 (de) * 2010-01-24 2015-02-25 Novartis AG Bestrahlte bioabbaubare polymermikropartikeln
EP2558072B1 (de) 2010-04-15 2018-09-26 The Washington University Prodrug-zusammensetzungen, prodrug-nanopartikel und anwendungsverfahren dafür
EP2568977A1 (de) 2010-05-11 2013-03-20 Cima Labs Inc. Alkoholresistente metoprololhaltige orale retard-dosierformen
US8946194B2 (en) 2010-10-08 2015-02-03 Board Of Regents, University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
US9095558B2 (en) 2010-10-08 2015-08-04 Board Of Regents, The University Of Texas System Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
WO2012050359A2 (ko) * 2010-10-14 2012-04-19 (주)아모레퍼시픽 리피드로 코팅된 하이드로겔 입자 및 이의 제조방법
WO2012148953A1 (en) * 2011-04-25 2012-11-01 Stc.Unm Solid compositions for pharmaceutical use
KR101255520B1 (ko) * 2011-10-28 2013-04-23 한국과학기술원 이중충하이드로젤 미세입자의 비등방성 부품을 이용한 미세수송체의 제조방법
BR112015013774A2 (pt) 2012-12-11 2017-07-11 Univ Texas membrana de hidrogel para prevenção de adesão
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
WO2015065547A1 (en) 2013-10-31 2015-05-07 Cima Labs Inc. Immediate release abuse-deterrent granulated dosage forms
KR102038751B1 (ko) * 2016-11-18 2019-10-30 연세대학교 산학협력단 복합 제형이 적용된 마이크로니들 어레이 및 이의 제조방법
US11980700B2 (en) 2017-03-08 2024-05-14 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
KR102129986B1 (ko) * 2018-08-30 2020-07-03 포항공과대학교 산학협력단 일산화질소 감응성을 갖는 아크릴아마이드계 고분자를 포함하는 염증성 질환 예방 또는 치료용 약학 조성물
US10799564B1 (en) 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
US12589083B2 (en) 2019-05-07 2026-03-31 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
US11324707B2 (en) 2019-05-07 2022-05-10 Clexio Biosciences Ltd. Abuse-deterrent dosage forms containing esketamine
GB201909280D0 (en) * 2019-06-27 2019-08-14 Enesi Pharma Ltd Solid dose formulation
KR102407470B1 (ko) * 2021-08-09 2022-06-10 인제대학교 산학협력단 하이드로겔에 담지된 약물의 방출량 검출 방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) * 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5036006A (en) * 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
JPH0725689B2 (ja) * 1986-10-07 1995-03-22 中外製薬株式会社 顆粒球コロニ−刺激因子を含有する徐放性製剤
SE456486B (sv) * 1987-03-27 1988-10-10 Ralf Andersson Sett och anordning for uppdelning av en smelta i droppar
US4994276A (en) * 1988-09-19 1991-02-19 Edward Mendell Co., Inc. Directly compressible sustained release excipient
US4925677A (en) * 1988-08-31 1990-05-15 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5041292A (en) * 1988-08-31 1991-08-20 Theratech, Inc. Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
US5053332A (en) * 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
EP0500799B1 (de) 1989-11-16 1998-01-14 Duke University Transformation von tierischen Hautzellen mit hilfe von Partikeln
EP0454044B1 (de) * 1990-04-25 1995-12-06 Hoechst Aktiengesellschaft Pharmakologische Zubereitung, enthaltend Polyelektrolytkomplexe in mikropartikulärer Form und mindestens einen Wirkstoff
GB9014871D0 (en) * 1990-07-05 1990-08-22 Erba Carlo Spa Drug delivery system for administering growth factor
WO1994009819A1 (en) 1992-11-03 1994-05-11 Secretech, Inc. Microcrystalline cellulose as an immune adjuvant
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
JP4619457B2 (ja) * 1993-11-18 2011-01-26 シルテックス、メディカル、リミテッド 徐放性製剤
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
DE69507321T2 (de) 1994-10-24 1999-07-15 Powderject Research Ltd., Oxford Nadellose spritze
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
GB9502879D0 (en) 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
GB9605690D0 (en) 1996-03-19 1996-05-22 Oxford Biosciences Ltd Particle delivery
GB9612629D0 (en) * 1996-06-17 1996-08-21 Oxford Biosciences Ltd Method for providing dense particle compositions for use in transdermal particle delivery
GB9619002D0 (en) * 1996-09-11 1996-10-23 Oxford Biosciences Ltd Particle delivery
WO1998013798A1 (de) 1996-09-26 1998-04-02 Wanzl Metallwarenfabrik Gmbh Einrichtung und verfahren zum einkaufen von ware
US6656508B2 (en) * 1997-04-17 2003-12-02 Amgen Inc. Sustained-release alginate gels
EP0888791A1 (de) 1997-07-04 1999-01-07 PowderJect Research Limited Spritze und dafür geeignete Medikamentenkapsel
EP0888790A1 (de) 1997-07-04 1999-01-07 PowderJect Research Limited Vorrichtung zur Abgabe von Medikamententeilchen
WO2000014547A1 (en) 1998-09-04 2000-03-16 Powderject Research Limited Immunodiagnostics using particle delivery methods
WO2000013573A1 (en) 1998-09-04 2000-03-16 Powderject Research Limited Monitoring methods using particle delivery methods
US5952232A (en) * 1998-09-17 1999-09-14 Rothman; James Edward Expandible microparticle intracellular delivery system
EP1117382B1 (de) 1998-10-01 2005-05-11 PowderJect Research Limited Sprühbeschichtete mikropartikel für nadellose spritzen
AU765429B2 (en) 1999-01-22 2003-09-18 Powderject Research Limited Method of enhancing needleless transdermal powdered drug delivery

Also Published As

Publication number Publication date
AU2309200A (en) 2000-08-25
CN1345232A (zh) 2002-04-17
BR0007974A (pt) 2001-10-30
IL144597A0 (en) 2002-05-23
IL144597A (en) 2007-03-08
CN1230152C (zh) 2005-12-07
PT1146861E (pt) 2005-10-31
EP1146861B1 (de) 2005-06-29
DE60021059T2 (de) 2006-05-18
WO2000045792A1 (en) 2000-08-10
CA2361555A1 (en) 2000-08-10
KR20010101994A (ko) 2001-11-15
JP2002536317A (ja) 2002-10-29
NZ513538A (en) 2004-02-27
US20020061336A1 (en) 2002-05-23
MXPA01007844A (es) 2005-06-06
WO2000045792A8 (en) 2001-11-29
AU780397B2 (en) 2005-03-17
US7022313B2 (en) 2006-04-04
ES2243229T3 (es) 2005-12-01
DE60021059D1 (de) 2005-08-04
EP1146861A1 (de) 2001-10-24
KR100845769B1 (ko) 2008-07-11

Similar Documents

Publication Publication Date Title
DE60021059D1 (de) Hydrogelpartikel formulierungen
DE60038183D1 (de) Verbindungen und zusammensetzungen zur abgabe aktiver wirkstoffe
BR0308137A (pt) Formulações de droga de liberação constante contendo um peptìdeo veìculo
EP1015008A4 (de) Verbindungen und zusammensetzungen zur administration aktiver stoffe
ATE391708T1 (de) Verbindungen und gemische zur verabreichung eines aktiven agens
IL140930A0 (en) Compounds and compositions for delivering active agents
BR0008590A (pt) Agente de entrega polimérico, composição, formade unidade de dosagem, método para administrarum agente biologicamente ativo a um animalnecessitando o agente, método para preparar umacomposição; e composto
EP1478406A4 (de) Zusammensetzungen zur abgabe von therapeutika und anderen materialien und verfahren zu ihrer herstellung und verwendung
ES2110377T1 (es) Formulacion galenica de fenofibrato y aplicacion de la misma.
IL195055A (en) Carboxylic acid components and compounds for transporting active carriers
EP1100522A4 (de) Verabreichung aktiver wirkstoffe über die lunge
ATE262329T1 (de) Formulierungen und verfahren zur verminderung der toxizität von anti-neoplastischen mitteln
DE60312523D1 (de) Orale, pharmazeutische darreichungsformen von flüssigen medikamenten mitverbesserter bioverfügbarkeit
ATE388687T1 (de) Medikamentöse verabreichung von nikotin in form von kaugummi
MXPA03007857A (es) Compuestos y composiciones para entregar agentes activos.
DE60024414T2 (de) Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen
ATE292453T1 (de) Antivirale arznei
DK1280558T3 (da) Halvfast indgivelsesvehikel og farmaceutiske sammensætninger
DE69731882D1 (de) Transdermal verabreichtes dextromethorphan als hustenmittel
TR200503846T2 (tr) Değiştirilmiş salimli ensülin sensitizörü için fterkip ve kullanımı
CO5200854A1 (es) Formulaciones farmaceuticas orales en capsulas de gelatina de hidroxipropilmetil celulosa que comprenden un derivado de camptotecina dentro de una matriz semisolida de polietilenglicol
TR200200683T2 (tr) Oral kontrollü salıverme formülasyonları.
PT1144420E (pt) Fosfatidilinositois sulfatados a sua preparacao e a sua utilizacao
MX9702899A (es) Compuestos y composiciones para suministrar agentes activos.
MY124346A (en) Medicated chewing gum delivery system for nicotine

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1146861

Country of ref document: EP

REN Ceased due to non-payment of the annual fee