ATE299492T1 - Cyclophilin-bindende ligande - Google Patents

Cyclophilin-bindende ligande

Info

Publication number
ATE299492T1
ATE299492T1 AT01270544T AT01270544T ATE299492T1 AT E299492 T1 ATE299492 T1 AT E299492T1 AT 01270544 T AT01270544 T AT 01270544T AT 01270544 T AT01270544 T AT 01270544T AT E299492 T1 ATE299492 T1 AT E299492T1
Authority
AT
Austria
Prior art keywords
sup
cyclophilin
binding ligand
bonds
double
Prior art date
Application number
AT01270544T
Other languages
English (en)
Inventor
Malcolm Douglas Walkinshaw
Paul Taylor
Nicholas John Turner
Sabine Lahja Flitsch
Original Assignee
Cyclacel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd
Application granted granted Critical
Publication of ATE299492T1 publication Critical patent/ATE299492T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
AT01270544T 2000-12-13 2001-12-13 Cyclophilin-bindende ligande ATE299492T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0030378.4A GB0030378D0 (en) 2000-12-13 2000-12-13 Compound
PCT/GB2001/005540 WO2002048178A2 (en) 2000-12-13 2001-12-13 Cyclophilin-binding ligands

Publications (1)

Publication Number Publication Date
ATE299492T1 true ATE299492T1 (de) 2005-07-15

Family

ID=9904993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01270544T ATE299492T1 (de) 2000-12-13 2001-12-13 Cyclophilin-bindende ligande

Country Status (8)

Country Link
US (1) US7223795B2 (de)
EP (1) EP1343754B1 (de)
AT (1) ATE299492T1 (de)
AU (1) AU2002222218A1 (de)
DE (1) DE60111956T2 (de)
ES (1) ES2241744T3 (de)
GB (1) GB0030378D0 (de)
WO (1) WO2002048178A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0012528D0 (en) * 2000-05-23 2000-07-12 Univ Palackeho Triterpenoid derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5234630B2 (de) * 1974-06-07 1977-09-05
BE831558A (fr) 1975-07-18 1975-11-17 Perfectionnement aux dispositifs d'ouverture d'exutoire de fumee et de chaleur
GB9422383D0 (en) 1994-11-05 1995-01-04 Wellcome Found Antibodies
GB9509557D0 (en) 1995-05-11 1995-07-05 Univ Dundee PCNA binding substance
GB9519275D0 (en) 1995-09-21 1995-11-22 Univ Dundee Substances and their therapeutic use
DE69736351D1 (de) 1996-05-08 2006-08-31 Cyclacel Ltd Methoden und mittel zur hemmung der cdk4-aktivität
AR010744A1 (es) 1996-12-09 2000-07-12 Guildford Pharmaceuticals Inc Inhibidores polipropilos de ciclofilina
GB9812675D0 (en) 1998-06-11 1998-08-12 Univ Edinburgh Peptides

Also Published As

Publication number Publication date
WO2002048178A2 (en) 2002-06-20
WO2002048178A3 (en) 2002-11-14
AU2002222218A1 (en) 2002-06-24
US7223795B2 (en) 2007-05-29
GB0030378D0 (en) 2001-01-24
EP1343754A2 (de) 2003-09-17
EP1343754B1 (de) 2005-07-13
ES2241744T3 (es) 2005-11-01
DE60111956T2 (de) 2006-03-30
DE60111956D1 (de) 2005-08-18
US20040077829A1 (en) 2004-04-22

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