ATE299846T1 - Transferhydrierungsverfahren - Google Patents

Transferhydrierungsverfahren

Info

Publication number
ATE299846T1
ATE299846T1 AT00949706T AT00949706T ATE299846T1 AT E299846 T1 ATE299846 T1 AT E299846T1 AT 00949706 T AT00949706 T AT 00949706T AT 00949706 T AT00949706 T AT 00949706T AT E299846 T1 ATE299846 T1 AT E299846T1
Authority
AT
Austria
Prior art keywords
transfer hydrogenation
bidentate ligands
hydrogenation process
iminium salts
employed
Prior art date
Application number
AT00949706T
Other languages
English (en)
Inventor
Juliette Martin
Lynne Alison Campbell
Original Assignee
Avecia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Pharmaceuticals Ltd filed Critical Avecia Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE299846T1 publication Critical patent/ATE299846T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36—Amides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Seasonings (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
AT00949706T 1999-08-14 2000-07-25 Transferhydrierungsverfahren ATE299846T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9919118.1A GB9919118D0 (en) 1999-08-14 1999-08-14 Transfer hydrogenation process
PCT/GB2000/002867 WO2001012574A1 (en) 1999-08-14 2000-07-25 Transfer hydrogenation process

Publications (1)

Publication Number Publication Date
ATE299846T1 true ATE299846T1 (de) 2005-08-15

Family

ID=10859084

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00949706T ATE299846T1 (de) 1999-08-14 2000-07-25 Transferhydrierungsverfahren

Country Status (19)

Country Link
US (1) US6696608B1 (de)
EP (1) EP1210305B1 (de)
JP (1) JP2003507353A (de)
KR (1) KR100787946B1 (de)
CN (1) CN1328230C (de)
AT (1) ATE299846T1 (de)
AU (1) AU779493B2 (de)
CA (1) CA2383266A1 (de)
CZ (1) CZ2002535A3 (de)
DE (1) DE60021394T2 (de)
DK (1) DK1210305T3 (de)
ES (1) ES2246246T3 (de)
GB (1) GB9919118D0 (de)
HU (1) HUP0202493A3 (de)
IL (2) IL147673A0 (de)
MX (1) MXPA02001499A (de)
NO (1) NO20020734L (de)
PT (1) PT1210305E (de)
WO (1) WO2001012574A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743921B2 (en) 2002-01-24 2004-06-01 Dsm Catalytica Pharmaceuticals, Inc. Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds
GB0424004D0 (en) * 2004-10-29 2004-12-01 Avecia Ltd Process
WO2008080138A1 (en) 2006-12-22 2008-07-03 Richmond Chemical Corporation Stereoinversion of amino acids
US7973110B2 (en) * 2008-06-16 2011-07-05 Construction Research & Technology Gmbh Copolymer synthesis process
US20110105798A1 (en) * 2008-06-27 2011-05-05 O'shea Paul Synthesis of chiral amines
CN101845056B (zh) * 2010-03-05 2012-08-29 中国科学院上海有机化学研究所 一类c1对称的手性二烯配体、合成方法及其在不对称反应中的应用
WO2017033134A1 (en) 2015-08-26 2017-03-02 Lupin Limited Enzymatic process for the for preparation of (r)-1-(1-naphthyl) ethylamine, an intermediate of cinacalcet hydrochloride
CN111433336B (zh) * 2017-10-17 2024-02-23 丝趣科尔卡有限公司 气味剂和包含气味剂的组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2900804B2 (ja) * 1994-10-18 1999-06-02 日本鋼管株式会社 プラグ耐用度に優れた継目無鋼管の製造方法
WO1998039276A1 (en) 1997-03-06 1998-09-11 Mitsui Chemicals Inc. Process for producing optically active amines
GB9706321D0 (en) * 1997-03-26 1997-05-14 Zeneca Ltd Catalytic hydrogenation

Also Published As

Publication number Publication date
JP2003507353A (ja) 2003-02-25
US6696608B1 (en) 2004-02-24
EP1210305A1 (de) 2002-06-05
NO20020734D0 (no) 2002-02-13
GB9919118D0 (en) 1999-10-13
CN1368945A (zh) 2002-09-11
KR20020026253A (ko) 2002-04-06
EP1210305B1 (de) 2005-07-20
DE60021394T2 (de) 2006-03-30
HUP0202493A2 (hu) 2002-11-28
HUP0202493A3 (en) 2003-11-28
AU779493B2 (en) 2005-01-27
PT1210305E (pt) 2005-11-30
IL147673A (en) 2007-10-31
CA2383266A1 (en) 2001-02-22
HK1049653A1 (en) 2003-05-23
NO20020734L (no) 2002-02-13
DE60021394D1 (de) 2005-08-25
KR100787946B1 (ko) 2007-12-24
AU6298200A (en) 2001-03-13
MXPA02001499A (es) 2002-10-23
IL147673A0 (en) 2002-08-14
DK1210305T3 (da) 2005-11-07
ES2246246T3 (es) 2006-02-16
WO2001012574A1 (en) 2001-02-22
CZ2002535A3 (cs) 2002-05-15
CN1328230C (zh) 2007-07-25

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