ATE300042T1 - Optische sensorvorrichtung mit evaneszenter felddetektion - Google Patents

Optische sensorvorrichtung mit evaneszenter felddetektion

Info

Publication number
ATE300042T1
ATE300042T1 AT99924961T AT99924961T ATE300042T1 AT E300042 T1 ATE300042 T1 AT E300042T1 AT 99924961 T AT99924961 T AT 99924961T AT 99924961 T AT99924961 T AT 99924961T AT E300042 T1 ATE300042 T1 AT E300042T1
Authority
AT
Austria
Prior art keywords
measurement
optical sensor
sensor device
field detection
evanescent field
Prior art date
Application number
AT99924961T
Other languages
English (en)
Inventor
Alfredo Emilio Bruno-Raimondi
Reinhard Voelkel
Gert Ludwig Duveneck
Carlo Stefan Effenhauser
Hans-Peter Herzig
Rene Daendliker
Original Assignee
Zeptosens Ag
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeptosens Ag, Novartis Erfind Verwalt Gmbh filed Critical Zeptosens Ag
Application granted granted Critical
Publication of ATE300042T1 publication Critical patent/ATE300042T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44782Apparatus specially adapted therefor of a plurality of samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4738Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474Details of optical heads therefor, e.g. using optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Gas-Insulated Switchgears (AREA)
AT99924961T 1998-05-14 1999-05-12 Optische sensorvorrichtung mit evaneszenter felddetektion ATE300042T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9810350.0A GB9810350D0 (en) 1998-05-14 1998-05-14 Organic compounds
PCT/EP1999/003296 WO1999058963A1 (en) 1998-05-14 1999-05-12 Sensing unit provided with separated detection light guiding

Publications (1)

Publication Number Publication Date
ATE300042T1 true ATE300042T1 (de) 2005-08-15

Family

ID=10832040

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99924961T ATE300042T1 (de) 1998-05-14 1999-05-12 Optische sensorvorrichtung mit evaneszenter felddetektion

Country Status (7)

Country Link
US (1) US6437345B1 (de)
EP (1) EP1078248B1 (de)
AT (1) ATE300042T1 (de)
AU (1) AU4143099A (de)
DE (1) DE69926230T2 (de)
GB (1) GB9810350D0 (de)
WO (1) WO1999058963A1 (de)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592733B1 (en) * 1999-11-12 2003-07-15 Motorola, Inc. Capillary electrophoresis devices incorporating optical waveguides
US6580507B2 (en) * 2000-03-02 2003-06-17 Sd Acquisition Inc. Single source, single detector chip, multiple-longitudinal channel electromagnetic radiation absorbance and fluorescence monitoring system
WO2002001194A1 (en) * 2000-06-25 2002-01-03 Affymetrix, Inc. Optically active substrates
DE10036457A1 (de) * 2000-07-26 2002-02-14 Giesing Michael Verwendung eines bildgebenden photoelektrischen Flächensensors zur Auswertung von Biochips und Bildgebungsverfahren hierfür
IL137625A0 (en) * 2000-08-01 2001-10-31 Sensis Ltd Detector for an electrophoresis apparatus
AU2001286511A1 (en) * 2000-08-15 2002-02-25 Nanostream, Inc. Optical devices with fluidic systems
AU2001289859A1 (en) 2000-09-05 2002-03-22 Zeptosens Ag Method for precipitating mono and multiple layers of organophosphoric and organophosphonic acids and the salts thereof in addition to use thereof
WO2002040998A2 (de) * 2000-11-17 2002-05-23 Zeptosens Ag Kit und verfahren zur multianalytbestimmung
JP3969699B2 (ja) * 2000-11-17 2007-09-05 日本板硝子株式会社 マイクロ化学システム用チップ部材、及び該チップ部材を用いたマイクロ化学システム
JP3741051B2 (ja) * 2001-05-10 2006-02-01 横河電機株式会社 バイオチップ読取装置
US9493805B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensors with enhanced activity retention for detection of organic compounds
US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
DE10133844B4 (de) * 2001-07-18 2006-08-17 Micronas Gmbh Verfahren und Vorrichtung zur Detektion von Analyten
EP1348757A1 (de) * 2002-03-27 2003-10-01 Micronas GmbH Vorrichtung und Verfahren zur Detektion von zellulären Vorgängen mittels Lumineszenzmessungen
US9157860B2 (en) * 2002-05-16 2015-10-13 Applied Biosystems, Llc Achromatic lens array
US6982166B2 (en) * 2002-05-16 2006-01-03 Applera Corporation Lens assembly for biological testing
US20030232427A1 (en) * 2002-06-18 2003-12-18 Montagu Jean I. Optically active substrates for examination of biological materials
US7751049B1 (en) * 2008-09-16 2010-07-06 Microglo, Llc Photo sensing fluid contamination and quality monitor
WO2004040295A1 (en) * 2002-10-31 2004-05-13 Nanostream, Inc. Parallel detection chromatography systems
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
AU2003275942A1 (en) * 2002-11-01 2004-05-25 Technical University Of Denmark A microfluidic system and a microdevice for velocity measurement, a method of performing measurements and use hereof
US6987263B2 (en) * 2002-12-13 2006-01-17 Nanostream, Inc. High throughput systems and methods for parallel sample analysis
US20060076482A1 (en) * 2002-12-13 2006-04-13 Hobbs Steven E High throughput systems and methods for parallel sample analysis
DE10317736A1 (de) * 2003-04-11 2004-10-28 Dr. Johannes Heidenhain Gmbh Abtasteinheit für eine Positionsmesseinrichtung zum optischen Abtasten einer Maßverkörperung
US7074327B2 (en) 2003-05-08 2006-07-11 Nanostream, Inc. Sample preparation for parallel chromatography
US7545494B2 (en) * 2003-07-23 2009-06-09 Bayer Technology Services Gmbh Analytical system and method for analyzing nonlinear optical signals
CN100491939C (zh) * 2003-12-26 2009-05-27 科学与工业研究委员会 光纤光学点温度传感器
JP4375031B2 (ja) 2004-01-28 2009-12-02 株式会社島津製作所 マイクロチップ処理方法及び装置
WO2006002150A1 (en) * 2004-06-22 2006-01-05 Applied Materials Israel, Ltd. Wafer inspection system
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
WO2006038149A1 (en) * 2004-10-01 2006-04-13 Koninklijke Philips Electronics N. V. Method and apparatus for the detection of labeling elements in a sample
DE602005010611D1 (de) * 2004-12-17 2008-12-04 Koninkl Philips Electronics Nv Mehrpunktuntersuchungsgerät
US7662614B2 (en) * 2005-01-14 2010-02-16 Samsung Electronics Co., Ltd. Biochip platform including dielectric particle layer and optical assay apparatus using the same
US8119995B2 (en) * 2005-07-21 2012-02-21 Koninklijke Philips Electronics N.V. Device for detection of excitation using a multiple spot arrangement
US20070196863A1 (en) * 2006-02-17 2007-08-23 Hanson Technologies, Inc. Prion protein detection
US9976192B2 (en) 2006-03-10 2018-05-22 Ldip, Llc Waveguide-based detection system with scanning light source
US9528939B2 (en) 2006-03-10 2016-12-27 Indx Lifecare, Inc. Waveguide-based optical scanning systems
US8288157B2 (en) 2007-09-12 2012-10-16 Plc Diagnostics, Inc. Waveguide-based optical scanning systems
US8675199B2 (en) 2006-03-10 2014-03-18 Plc Diagnostics, Inc. Waveguide-based detection system with scanning light source
US9423397B2 (en) 2006-03-10 2016-08-23 Indx Lifecare, Inc. Waveguide-based detection system with scanning light source
EP2535427A3 (de) 2006-05-17 2013-04-24 California Institute of Technology Thermisches Wechselbeanspruchungssystem
US8207509B2 (en) 2006-09-01 2012-06-26 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
AU2007289057C1 (en) * 2006-09-01 2014-01-16 Pacific Biosciences Of California, Inc. Substrates, systems and methods for analyzing materials
US9796998B2 (en) 2007-04-09 2017-10-24 Colorado State University Research Foundation Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations
US8119998B2 (en) * 2008-01-04 2012-02-21 Pion, Inc. Methods and systems for in situ physicochemical property testing
EP3045542B1 (de) 2008-03-28 2016-11-16 Pacific Biosciences of California, Inc. Verfahren zur nukleinsäuresequenzierung
GB2461026B (en) 2008-06-16 2011-03-09 Plc Diagnostics Inc System and method for nucleic acids sequencing by phased synthesis
WO2010033193A2 (en) 2008-09-16 2010-03-25 Pacific Biosciences Of California, Inc. Substrates and optical systems and methods of use thereof
US8247216B2 (en) 2008-09-30 2012-08-21 Pacific Biosciences Of California, Inc. Ultra-high multiplex analytical systems and methods
EP2189793A1 (de) * 2008-11-21 2010-05-26 Micronas GmbH Verfahren zum Regenerieren eines Biosensors
US8455844B2 (en) 2009-03-11 2013-06-04 Colorado State University Research Foundation System and method for time-division multiplexed optical sensing of biosensors
EP2446249B1 (de) * 2009-06-24 2020-08-05 Koninklijke Philips N.V. Optischer biosensor mit fokussierungsoptik
JP2011059095A (ja) * 2009-08-12 2011-03-24 Sony Corp 光検出装置
US9410891B2 (en) 2010-02-19 2016-08-09 Pacific Biosciences Of California, Inc. Optics collection and detection system and method
US8994946B2 (en) 2010-02-19 2015-03-31 Pacific Biosciences Of California, Inc. Integrated analytical system and method
US8335029B2 (en) * 2010-03-11 2012-12-18 Pacific Biosciences Of California, Inc. Micromirror arrays having self aligned features
EP2375242A1 (de) 2010-04-06 2011-10-12 FOM Institute for Atomic and Moleculair Physics Integrierte Vorrichtung zum Abtasten von Plasmonennanokavitäten
US8809810B2 (en) * 2010-05-20 2014-08-19 Honeywell International Inc. Microarray reader based on evanescent wave detection
WO2012018364A1 (en) * 2010-07-08 2012-02-09 The Board Of Trustees Of The University Of Illinois Multi-color fluorescence enhancement from a photonic crystal surface
DE102010064391A1 (de) 2010-10-29 2012-05-03 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Verfahren zur Bestimmung eines Analytgehalts einer Flüssigkeitsprobe mittels eines Bioanalysators
US10024797B2 (en) 2010-11-22 2018-07-17 Colorado State University Research Foundation Biosensing systems for measurement of lactose
EP2694949A1 (de) 2011-04-05 2014-02-12 Integrated Plasmonics Corporation Integrierte plasmonischer sensor und vorrichtung
WO2013019982A2 (en) 2011-08-02 2013-02-07 Colorado State University Research Foundation Biosensing system with extended lifetime via cofactor recycling
JP2014532873A (ja) 2011-11-03 2014-12-08 ベリフード リミテッド エンドユーザ食品分析のための低費用分光分析システム
US9372308B1 (en) 2012-06-17 2016-06-21 Pacific Biosciences Of California, Inc. Arrays of integrated analytical devices and methods for production
WO2014066826A1 (en) 2012-10-25 2014-05-01 Colorado State University Research Foundation Improved multi-analyte optical sensor
WO2014099776A1 (en) 2012-12-18 2014-06-26 Pacific Biosciences Of California, Inc. Illumination of optical analytical devices
US9624540B2 (en) 2013-02-22 2017-04-18 Pacific Biosciences Of California, Inc. Integrated illumination of optical analytical devices
CN105593651B (zh) 2013-08-02 2019-06-07 威利食品有限公司 光谱测定系统和方法、光谱设备和系统
US9983135B2 (en) 2013-11-17 2018-05-29 Quantum-Si Incorporated Active-source-pixel, integrated device for rapid analysis of biological and chemical specimens
NZ720871A (en) 2013-12-10 2020-03-27 Illumina Inc Biosensors for biological or chemical analysis and methods of manufacturing the same
JP2017505901A (ja) 2014-01-03 2017-02-23 ベリフード, リミテッドVerifood, Ltd. 分光システム、方法、および用途
US10018566B2 (en) 2014-02-28 2018-07-10 Ldip, Llc Partially encapsulated waveguide based sensing chips, systems and methods of use
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
BR112017002485B1 (pt) 2014-08-08 2020-12-01 Quantum-Si Incorporated circuito integrado e método de fotodetecção
JP6812341B2 (ja) 2014-08-08 2021-01-13 クアンタム−エスアイ インコーポレイテッドQuantum−Si Incorporated 分子の探索、検出及び解析のための光学システム及びアッセイチップ
CA2957546A1 (en) 2014-08-08 2016-02-11 Quantum-Si Incorporated Integrated device with external light source for probing, detecting, and analyzing molecules
TWI692633B (zh) 2014-08-27 2020-05-01 美商加州太平洋生物科學公司 整合式分析裝置之陣列
WO2016063284A2 (en) 2014-10-23 2016-04-28 Verifood, Ltd. Accessories for handheld spectrometer
US10302972B2 (en) 2015-01-23 2019-05-28 Pacific Biosciences Of California, Inc. Waveguide transmission
DE112015006100T5 (de) * 2015-02-03 2017-11-30 Hitachi High-Technologies Corporation Mehrfarbenerfassungsvorrichtung
WO2016125164A2 (en) 2015-02-05 2016-08-11 Verifood, Ltd. Spectrometry system applications
WO2016125165A2 (en) 2015-02-05 2016-08-11 Verifood, Ltd. Spectrometry system with visible aiming beam
US11181479B2 (en) 2015-02-27 2021-11-23 Ldip, Llc Waveguide-based detection system with scanning light source
EP3271762B1 (de) 2015-03-16 2023-01-04 Pacific Biosciences of California, Inc. Analysesystem umfassend integrierte vorrichtungen und systeme zur optischen freiraumkopplung
CA2983882C (en) 2015-05-07 2023-10-03 Scott E. Helgesen Multiprocessor pipeline architecture
US11466316B2 (en) 2015-05-20 2022-10-11 Quantum-Si Incorporated Pulsed laser and bioanalytic system
US10246742B2 (en) 2015-05-20 2019-04-02 Quantum-Si Incorporated Pulsed laser and bioanalytic system
US10605730B2 (en) 2015-05-20 2020-03-31 Quantum-Si Incorporated Optical sources for fluorescent lifetime analysis
US10365434B2 (en) 2015-06-12 2019-07-30 Pacific Biosciences Of California, Inc. Integrated target waveguide devices and systems for optical coupling
JP6621844B2 (ja) * 2015-12-16 2019-12-18 オリンパス株式会社 蛍光観察装置および蛍光観察システム、インキュベータ
WO2017117462A1 (en) * 2015-12-30 2017-07-06 Bio-Rad Laboratories, Inc. Detection and signal processing system for particle assays
TWI734748B (zh) 2016-02-17 2021-08-01 美商太斯萊特健康股份有限公司 用於生命期成像及偵測應用之感測器及裝置
EP3488204A4 (de) 2016-07-20 2020-07-22 Verifood Ltd. Zubehör für handhaltbares spektrometer
WO2018112444A1 (en) 2016-12-16 2018-06-21 Quantum-Si Incorporated Compact mode-locked laser module
CA3047108A1 (en) 2016-12-16 2018-06-21 Quantum-Si Incorporated Compact beam shaping and steering assembly
CN118099177A (zh) 2016-12-22 2024-05-28 宽腾矽公司 具有直接合并像素的整合式光电侦测器
WO2018150559A1 (ja) * 2017-02-20 2018-08-23 株式会社日立ハイテクノロジーズ 分析システム及び分析方法
TW201915473A (zh) 2017-07-24 2019-04-16 美商寬騰矽公司 手持,大量平行之生物光電裝置
BR112020000799A2 (pt) 2017-07-24 2020-07-14 Quantum-Si Incorporated estruturas fotônicas de rejeição óptica
US11808700B2 (en) 2018-06-15 2023-11-07 Quantum-Si Incorporated Data acquisition control for advanced analytic instruments having pulsed optical sources
US11391626B2 (en) 2018-06-22 2022-07-19 Quantum-Si Incorporated Integrated photodetector with charge storage bin of varied detection time
EP3864384A4 (de) 2018-10-08 2022-06-29 Verifood Ltd. Zubehör für optische spektrometer
WO2020176577A1 (en) * 2019-02-27 2020-09-03 Gentex Corporation Tactical chemical detector
CN114303082B (zh) 2019-06-14 2024-12-10 宽腾矽公司 具有提升的波束校准灵敏度的分割光栅耦合器
CN115210969A (zh) 2020-01-14 2022-10-18 宽腾矽公司 调幅激光器
US12535420B2 (en) 2020-02-18 2026-01-27 Pacific Biosciences Of California, Inc. Highly multiplexed nucleic acid sequencing systems
JP7329658B2 (ja) * 2020-10-07 2023-08-18 株式会社日立ハイテク 発光検出装置
JP2024516290A (ja) 2021-05-04 2024-04-12 パシフィック・バイオサイエンシズ・オブ・カリフォルニア・インク. 縮小されたスケールの単位セルを伴う統合された分析デバイスのアレイ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3618605A1 (de) * 1986-06-03 1987-12-10 Europ Lab Molekularbiolog Vorrichtung zur detektion von zur photonenemission anregbaren stoffen
FR2654212A1 (fr) * 1989-11-03 1991-05-10 Ardt Procede d'analyse spectroscopique ponctuelle de la lumiere diffractee ou absorbee par une substance placee dans un champ proche, et microscopes optiques a balayage en champ proche mettant en óoeuvre ce procede.
JPH10513553A (ja) * 1995-01-23 1998-12-22 マーレイ,アンソニー・ジェイ 生物学的分子の分析
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5701181A (en) * 1995-05-12 1997-12-23 Bayer Corporation Fiber optic diffuse light reflectance sensor utilized in the detection of occult blood

Also Published As

Publication number Publication date
DE69926230D1 (de) 2005-08-25
WO1999058963A1 (en) 1999-11-18
EP1078248A1 (de) 2001-02-28
AU4143099A (en) 1999-11-29
EP1078248B1 (de) 2005-07-20
GB9810350D0 (en) 1998-07-15
DE69926230T2 (de) 2006-05-24
US6437345B1 (en) 2002-08-20

Similar Documents

Publication Publication Date Title
DE69926230D1 (de) Optische sensorvorrichtung mit evaneszenter felddetektion
DK2325622T3 (da) Optisk-baseret føleindretning
US6014213A (en) High dynamic range apparatus for separation and detection of polynucleotide fragments
ATE387623T1 (de) Spektrophotometer mit mehreren weglängen
BR9811502B1 (pt) sensor de pressão, sistema de medição de pressão e método para medir a pressão aplicada ao sensor.
ATE236388T1 (de) Optische messungen mit räumlicher auflösung
EP0616211A1 (de) Optische Detektorvorrichtung für die chemische Analyse von kleinen fluiden Probenvolumina
DE69634660D1 (de) Optischer fluoreszenzsensor
DE69912061D1 (de) Verbesserungen bezüglich der Messung einer Teilchengrössenverteilung
WO1998041854A9 (en) High dynamic range apparatus for separation and detection of polynucleotide fragments
DK0988525T3 (da) Metode til karakterisering af prøver på basis af intermediære statistiske data
CN115046974A (zh) 荧光性检测能力到光吸收率测量装置中的结合
ITMI912292A1 (it) Dispositivo per a rivelazione della presenza e della qualita' della fiamma attraverso la captazione e l'analisi di radiazioni elettromagnetiche di diversa lunghezza d'onda
US6319705B1 (en) Microchip device for electrophoresis
ATE232976T1 (de) Optische messanordnung zur bestimmung der transmissions- und streustrahlung
Bachteler et al. Sensitive fluorescence detection in capillary electrophoresis using laser diodes and multiplex dyes
KR930023713A (ko) 힘측정용 변환기
GB2200987A (en) Ultraviolet radiation detector
KR890007057A (ko) 변위 탐지
JPH03503314A (ja) 蛍光測定器
CA2017031A1 (en) Apparatus for the measurement of aerosols and dust or the like distributed in air
JPS6461622A (en) Temperature measuring instrument
SE8503358D0 (sv) Fotometrisk koppling
RU2005131345A (ru) Сцинтилляционный детектор
SU1254847A1 (ru) Фотометр дл измерени прозрачности материалов

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties