ATE300312T1 - Lieferung von immunogenen molekülen unter verwendung von hbsag partikeln - Google Patents

Lieferung von immunogenen molekülen unter verwendung von hbsag partikeln

Info

Publication number: ATE300312T1
Authority: AT; Austria
Prior art keywords: hbsag particles; particles; delivery; immunogenic molecules; hbsag
Prior art date: 1998-02-03

Application number

AT99902800T

Other languages

English (en)

Inventor

Jorg Reimann

Yechezkel Barenholz

Dvorah Diminsky

Reinhold Schirmbeck

Original Assignee

Yissum Res Dev Co

Reimann Joerg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-03

Filing date

1999-01-29

Publication date

2005-08-15

1999-01-29 Application filed by Yissum Res Dev Co, Reimann Joerg filed Critical Yissum Res Dev Co

2005-08-15 Application granted granted Critical

2005-08-15 Publication of ATE300312T1 publication Critical patent/ATE300312T1/de

Links

239000002245 particle Substances 0.000 title abstract 5
230000002163 immunogen Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
230000004044 response Effects 0.000 abstract 2
102000004127 Cytokines Human genes 0.000 abstract 1
108090000695 Cytokines Proteins 0.000 abstract 1
230000000890 antigenic effect Effects 0.000 abstract 1
238000005538 encapsulation Methods 0.000 abstract 1
230000000763 evoking effect Effects 0.000 abstract 1
230000028993 immune response Effects 0.000 abstract 1
230000003308 immunostimulating effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AT99902800T 1998-02-03 1999-01-29 Lieferung von immunogenen molekülen unter verwendung von hbsag partikeln ATE300312T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7347698P	1998-02-03	1998-02-03
PCT/IL1999/000060 WO1999039736A2 (en)	1998-02-03	1999-01-29	DELIVERY OF IMMUNOGENIC MOLECULES VIA HBsAg PARTICLES

Publications (1)

Publication Number	Publication Date
ATE300312T1 true ATE300312T1 (de)	2005-08-15

Family

ID=22113916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99902800T ATE300312T1 (de)	1998-02-03	1999-01-29	Lieferung von immunogenen molekülen unter verwendung von hbsag partikeln

Country Status (9)

Country	Link
EP (1)	EP1053018B1 (de)
JP (1)	JP4480267B2 (de)
AT (1)	ATE300312T1 (de)
AU (1)	AU755957B2 (de)
CA (1)	CA2319599C (de)
DE (1)	DE69926342T2 (de)
DK (1)	DK1053018T3 (de)
ES (1)	ES2242376T3 (de)
WO (1)	WO1999039736A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPQ912000A0 (en) *	2000-07-31	2000-08-24	Crown In The Right Of The Queensland Department Of Health, The	Improved virus like particles
DE10106235A1 (de) *	2001-02-10	2002-08-22	Bosch Gmbh Robert	Wischarm
AU2004233873B2 (en)	2003-04-25	2010-11-18	The Penn State Research Foundation	Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
CU23405A1 (es) *	2003-10-20	2009-08-04	Ct Ingenieria Genetica Biotech	Composiciones farmacéuticas para uso terapéutico
US9603921B2 (en)	2004-10-27	2017-03-28	Janssen Vaccines Ag	Virosome particles comprising antigens from influenza virus and hepatitis b virus
JP2009120532A (ja) *	2007-11-14	2009-06-04	Osaka Univ	糖及び糖鎖認識機構を利用する物質送達用及びバイオイメージング用バイオナノカプセル

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5039522A (en) *	1988-01-29	1991-08-13	New York Blood Center, Inc.	Immunogens containing peptides with an attached hydrophobic tail for adsorption to hepatitis B virus surface antigen
WO1998052962A1 (en) *	1997-05-19	1998-11-26	Merck & Co., Inc.	Oligonucleotide adjuvant

1999
- 1999-01-29 AU AU22973/99A patent/AU755957B2/en not_active Ceased
- 1999-01-29 AT AT99902800T patent/ATE300312T1/de not_active IP Right Cessation
- 1999-01-29 DE DE69926342T patent/DE69926342T2/de not_active Expired - Lifetime
- 1999-01-29 CA CA2319599A patent/CA2319599C/en not_active Expired - Fee Related
- 1999-01-29 EP EP99902800A patent/EP1053018B1/de not_active Expired - Lifetime
- 1999-01-29 ES ES99902800T patent/ES2242376T3/es not_active Expired - Lifetime
- 1999-01-29 JP JP2000530233A patent/JP4480267B2/ja not_active Expired - Fee Related
- 1999-01-29 WO PCT/IL1999/000060 patent/WO1999039736A2/en not_active Ceased
- 1999-01-29 DK DK99902800T patent/DK1053018T3/da active

Also Published As

Publication number	Publication date
DK1053018T3 (da)	2005-08-15
EP1053018B1 (de)	2005-07-27
ES2242376T3 (es)	2005-11-01
JP4480267B2 (ja)	2010-06-16
EP1053018A2 (de)	2000-11-22
WO1999039736A2 (en)	1999-08-12
DE69926342T2 (de)	2006-01-12
AU755957B2 (en)	2003-01-02
AU2297399A (en)	1999-08-23
DE69926342D1 (de)	2005-09-01
CA2319599C (en)	2011-04-19
JP2002502828A (ja)	2002-01-29
WO1999039736A3 (en)	1999-09-23
CA2319599A1 (en)	1999-08-12

Legal Events

Date

Code

Title

Description

2006-05-15

UEP

Publication of translation of european patent specification

Ref document number: 1053018

Country of ref document: EP

2010-10-15

REN

Ceased due to non-payment of the annual fee

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