ATE302203T1 - Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen - Google Patents

Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen

Info

Publication number: ATE302203T1
Authority: AT; Austria
Prior art keywords: pyrazolopyrimidine; pharmaceutical preparations; preparations containing; containing same; pyrazolotriazine
Prior art date: 2002-03-07

Application number

AT03713672T

Other languages

English (en)

Inventor

Kristjan Gudmundsson

Brian A Johns

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-07

Filing date

2003-02-24

Publication date

2005-09-15

2003-02-24 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2005-09-15 Application granted granted Critical

2005-09-15 Publication of ATE302203T1 publication Critical patent/ATE302203T1/de

Links

PEYVWBGHBCDXRT-UHFFFAOYSA-N N1=NNC2=CN=NC2=C1 Chemical class N1=NNC2=CN=NC2=C1 PEYVWBGHBCDXRT-UHFFFAOYSA-N 0.000 title 1
OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical compound C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT03713672T 2002-03-07 2003-02-24 Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen ATE302203T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36229802P	2002-03-07	2002-03-07
PCT/US2003/005704 WO2003076441A1 (en)	2002-03-07	2003-02-24	Pyrazolopyrimidine and pyrazolotriazine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
ATE302203T1 true ATE302203T1 (de)	2005-09-15

Family

ID=27805154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03713672T ATE302203T1 (de)	2002-03-07	2003-02-24	Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen

Country Status (8)

Country	Link
US (2)	US7247626B2 (de)
EP (1)	EP1485385B1 (de)
JP (1)	JP2005525382A (de)
AT (1)	ATE302203T1 (de)
AU (1)	AU2003217712A1 (de)
DE (1)	DE60301339T2 (de)
ES (1)	ES2245772T3 (de)
WO (1)	WO2003076441A1 (de)

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US7329658B2 (en)	2003-02-06	2008-02-12	Pfizer Inc	Cannabinoid receptor ligands and uses thereof
US7723336B2 (en)	2005-09-22	2010-05-25	Bristol-Myers Squibb Company	Fused heterocyclic compounds useful as kinase modulators
WO2009100375A1 (en)	2008-02-06	2009-08-13	Bristol-Myers Squibb Company	Substituted imidazopyridazines useful as kinase inhibitors
UA103319C2 (en)	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
AR081810A1 (es)	2010-04-07	2012-10-24	Bayer Cropscience Ag	Piridinilpirazoles biciclicos
EP2402344A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazolkondensierte bicyclische Verbindungen
EP2402345A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazole kondensierte bizyclische Verbindungen
EP2402337A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazolopyridin-Verbindungen
EP2402343A1 (de)	2010-06-29	2012-01-04	Basf Se	Pyrazole kondensierte bizyclische Verbindungen
CA2889919C (en)	2012-11-16	2021-08-17	University Health Network	Pyrazolopyrimidine compounds
US11066404B2 (en)	2018-10-11	2021-07-20	Incyte Corporation	Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
US11384083B2 (en)	2019-02-15	2022-07-12	Incyte Corporation	Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
TW202100520A (zh)	2019-03-05	2021-01-01	美商英塞特公司	作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
WO2020205560A1 (en)	2019-03-29	2020-10-08	Incyte Corporation	Sulfonylamide compounds as cdk2 inhibitors
WO2020223469A1 (en)	2019-05-01	2020-11-05	Incyte Corporation	N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
US11447494B2 (en)	2019-05-01	2022-09-20	Incyte Corporation	Tricyclic amine compounds as CDK2 inhibitors
CA3150681A1 (en)	2019-08-14	2021-02-18	Incyte Corporation	Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors
US11851426B2 (en)	2019-10-11	2023-12-26	Incyte Corporation	Bicyclic amines as CDK2 inhibitors
US11981671B2 (en)	2021-06-21	2024-05-14	Incyte Corporation	Bicyclic pyrazolyl amines as CDK2 inhibitors
US11976073B2 (en)	2021-12-10	2024-05-07	Incyte Corporation	Bicyclic amines as CDK2 inhibitors

Family Cites Families (25)

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JPH11505524A (ja)	1995-05-01	1999-05-21	藤沢薬品工業株式会社	イミダゾ１，２−ａピリジンおよびイミダゾ１，２−ａピリデジン誘導体、および骨吸収阻害剤としてのその用途
HU229024B1 (en)	1996-07-24	2013-07-29	Bristol Myers Squibb Pharma Co	Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof
US6313124B1 (en) *	1997-07-23	2001-11-06	Dupont Pharmaceuticals Company	Tetrazine bicyclic compounds
JP3621706B2 (ja)	1996-08-28	2005-02-16	ファイザー・インク	置換された６，５―ヘテロ―二環式誘導体
AU7966198A (en)	1997-06-13	1998-12-30	Smithkline Beecham Corporation	Novel pyrazole and pyrazoline substituted compounds
JP2000038350A (ja)	1998-05-18	2000-02-08	Yoshitomi Pharmaceut Ind Ltd	糖尿病治療薬
FR2779724B1 (fr)	1998-06-10	2001-04-20	Rhone Poulenc Rorer Sa	Derives du pyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent
AU4331500A (en)	1999-04-06	2000-10-23	Du Pont Pharmaceuticals Company	Pyrazolotriazines as crf antagonists
ES2277855T3 (es)	1999-09-30	2007-08-01	Neurogen Corporation	Pirazolo-(1,5-a)-1,5-pirimidinas y pirazolo-(1,5-a)-1,3,5-triazinas amino sustituidas.
CA2379585C (en)	1999-09-30	2006-06-20	James W. Darrow	Certain alkylene diamine-substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines
GB0016787D0 (en)	2000-07-07	2000-08-30	Pfizer Ltd	Compounds useful in therapy
JP2004515550A (ja)	2000-12-15	2004-05-27	グラクソグループリミテッド	治療用化合物
ATE301653T1 (de)	2000-12-15	2005-08-15	Glaxo Group Ltd	Pyrazolopyridine
GB0103926D0 (en)	2001-02-17	2001-04-04	Astrazeneca Ab	Chemical compounds
WO2002072581A2 (en)	2001-03-08	2002-09-19	Smithkline Beecham Corporation	Pyrazolopyriadine derivatives
WO2002078701A1 (en)	2001-03-30	2002-10-10	Smithkline Beecham Corporation	Use of pyrazolopyridines as therapeutic compounds
WO2002078700A1 (en)	2001-03-30	2002-10-10	Smithkline Beecham Corporation	Pyralopyridines, process for their preparation and use as therapteutic compounds
ES2266487T3 (es)	2001-04-10	2007-03-01	Smithkline Beecham Corporation	Compuestos de pirazolopirina antivirales.
ATE296826T1 (de)	2001-04-27	2005-06-15	Smithkline Beecham Corp	Pyrazolo(1,5)pyridinderivate
ATE337316T1 (de)	2001-06-21	2006-09-15	Smithkline Beecham Corp	Imidazo 1,2-aöpyridin-derivate zur prophylaxe und behandlung von herpes-infektionen
US20040214834A1 (en)	2001-09-07	2004-10-28	Kristjan Gudmunsson	Pyrazolo-pyridines for the treatment of herpes infections
EP1432712B1 (de)	2001-10-05	2006-05-17	SmithKline Beecham Corporation	Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion
JP2005516916A (ja)	2001-12-11	2005-06-09	スミスクラインビーチャムコーポレーション	抗ヘルペス薬としてのピラゾロ−ピリジン誘導体
JP2005529919A (ja)	2002-05-10	2005-10-06	スミスクラインビーチャムコーポレーション	治療用化合物
JP2006504728A (ja)	2002-10-03	2006-02-09	スミスクラインビーチャムコーポレーション	ピラソロピリジン誘導体系治療用化合物

2003
- 2003-02-24 DE DE60301339T patent/DE60301339T2/de not_active Expired - Fee Related
- 2003-02-24 JP JP2003574658A patent/JP2005525382A/ja active Pending
- 2003-02-24 WO PCT/US2003/005704 patent/WO2003076441A1/en not_active Ceased
- 2003-02-24 AT AT03713672T patent/ATE302203T1/de not_active IP Right Cessation
- 2003-02-24 EP EP03713672A patent/EP1485385B1/de not_active Expired - Lifetime
- 2003-02-24 ES ES03713672T patent/ES2245772T3/es not_active Expired - Lifetime
- 2003-02-24 AU AU2003217712A patent/AU2003217712A1/en not_active Abandoned
- 2003-02-24 US US10/505,386 patent/US7247626B2/en not_active Expired - Fee Related
2007
- 2007-05-30 US US11/755,067 patent/US20070232623A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1485385A1 (de)	2004-12-15
ES2245772T3 (es)	2006-01-16
JP2005525382A (ja)	2005-08-25
DE60301339D1 (de)	2005-09-22
EP1485385B1 (de)	2005-08-17
AU2003217712A1 (en)	2003-09-22
US20070232623A1 (en)	2007-10-04
WO2003076441A1 (en)	2003-09-18
US7247626B2 (en)	2007-07-24
US20050124616A1 (en)	2005-06-09
DE60301339T2 (de)	2006-03-09

Legal Events

Date	Code	Title	Description
2006-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE365740T1 (de)	2007-07-15	Substituierte pyrazolopyrimidine
ATE302203T1 (de)	2005-09-15	Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen
DE60212949D1 (de)	2006-08-17	Antivirale pyrazolopyridin verbindungen
ATE296826T1 (de)	2005-06-15	Pyrazolo(1,5)pyridinderivate
ATE433447T1 (de)	2009-06-15	Pyrimiidinverbindungen
DE60112609D1 (en)	2005-09-15	Pyrazolopyridine
SE0301700D0 (sv)	2003-06-10	Novel compounds
IS6658A (is)	2002-12-17	Ný efnasambönd
IS6520A (is)	2002-08-22	Ný efnasambönd
SE9904505D0 (sv)	1999-12-09	Novel compounds
ATE300541T1 (de)	2005-08-15	Pyrazolopyridinderivate
NO20050525L (no)	2005-05-06	Benzimidazol-1-yl-tiofenforbindelser for behandling av cancer
SE0302139D0 (sv)	2003-07-28	Novel compounds
MXPA05011076A (es)	2006-01-24	Derivados de quinazolina para el tratamiento de cancer.
MXPA05012247A (es)	2006-02-10	Derivados de bencimidazol nuevos.
DE60001586D1 (de)	2003-04-10	Diphenyl-piperidin derivate
SE9804212D0 (sv)	1998-12-04	Compounds
DE60221537D1 (de)	2007-09-13	Pteridinon-derivate als modulatoren der chemokinrezeptor-aktivität
SE0101038D0 (sv)	2001-03-23	Novel compounds
DE60208694D1 (de)	2006-04-06	Piperidinylmorpholinylderivate als modulatoren der aktivität des chemokinrezeptors
SE0303280D0 (sv)	2003-12-05	Novel compounds
DE60222465D1 (de)	2007-10-25	Pyrazolopyridin-derivate als antiherpesmittel
SE9902551D0 (sv)	1999-07-02	Novel compounds
ATE274515T1 (de)	2004-09-15	Pyrazolopyridinderivate
SE0302755D0 (sv)	2003-10-17	Novel compounds