ATE302203T1 - Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen - Google Patents
Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungenInfo
- Publication number
- ATE302203T1 ATE302203T1 AT03713672T AT03713672T ATE302203T1 AT E302203 T1 ATE302203 T1 AT E302203T1 AT 03713672 T AT03713672 T AT 03713672T AT 03713672 T AT03713672 T AT 03713672T AT E302203 T1 ATE302203 T1 AT E302203T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazolopyrimidine
- pharmaceutical preparations
- preparations containing
- containing same
- pyrazolotriazine
- Prior art date
Links
- PEYVWBGHBCDXRT-UHFFFAOYSA-N N1=NNC2=CN=NC2=C1 Chemical class N1=NNC2=CN=NC2=C1 PEYVWBGHBCDXRT-UHFFFAOYSA-N 0.000 title 1
- OGEBRHQLRGFBNV-RZDIXWSQSA-N chembl2036808 Chemical compound C12=NC(NCCCC)=NC=C2C(C=2C=CC(F)=CC=2)=NN1C[C@H]1CC[C@H](N)CC1 OGEBRHQLRGFBNV-RZDIXWSQSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36229802P | 2002-03-07 | 2002-03-07 | |
| PCT/US2003/005704 WO2003076441A1 (en) | 2002-03-07 | 2003-02-24 | Pyrazolopyrimidine and pyrazolotriazine derivatives and pharmaceutical compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE302203T1 true ATE302203T1 (de) | 2005-09-15 |
Family
ID=27805154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03713672T ATE302203T1 (de) | 2002-03-07 | 2003-02-24 | Pyrazolopyrimidin- und pyrazolotriazinderivate und diese enthaltende pharmazeutische zubereitungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7247626B2 (de) |
| EP (1) | EP1485385B1 (de) |
| JP (1) | JP2005525382A (de) |
| AT (1) | ATE302203T1 (de) |
| AU (1) | AU2003217712A1 (de) |
| DE (1) | DE60301339T2 (de) |
| ES (1) | ES2245772T3 (de) |
| WO (1) | WO2003076441A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7329658B2 (en) * | 2003-02-06 | 2008-02-12 | Pfizer Inc | Cannabinoid receptor ligands and uses thereof |
| US7723336B2 (en) | 2005-09-22 | 2010-05-25 | Bristol-Myers Squibb Company | Fused heterocyclic compounds useful as kinase modulators |
| WO2009100375A1 (en) | 2008-02-06 | 2009-08-13 | Bristol-Myers Squibb Company | Substituted imidazopyridazines useful as kinase inhibitors |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| AR081810A1 (es) | 2010-04-07 | 2012-10-24 | Bayer Cropscience Ag | Piridinilpirazoles biciclicos |
| EP2402345A1 (de) | 2010-06-29 | 2012-01-04 | Basf Se | Pyrazole kondensierte bizyclische Verbindungen |
| EP2402343A1 (de) | 2010-06-29 | 2012-01-04 | Basf Se | Pyrazole kondensierte bizyclische Verbindungen |
| EP2402337A1 (de) | 2010-06-29 | 2012-01-04 | Basf Se | Pyrazolopyridin-Verbindungen |
| EP2402344A1 (de) | 2010-06-29 | 2012-01-04 | Basf Se | Pyrazolkondensierte bicyclische Verbindungen |
| EP2920181B1 (de) | 2012-11-16 | 2019-01-09 | University Health Network | Pyrazolopyrimidinverbindungen |
| US11066404B2 (en) | 2018-10-11 | 2021-07-20 | Incyte Corporation | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors |
| US11384083B2 (en) | 2019-02-15 | 2022-07-12 | Incyte Corporation | Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors |
| US11472791B2 (en) | 2019-03-05 | 2022-10-18 | Incyte Corporation | Pyrazolyl pyrimidinylamine compounds as CDK2 inhibitors |
| WO2020205560A1 (en) | 2019-03-29 | 2020-10-08 | Incyte Corporation | Sulfonylamide compounds as cdk2 inhibitors |
| US11440914B2 (en) | 2019-05-01 | 2022-09-13 | Incyte Corporation | Tricyclic amine compounds as CDK2 inhibitors |
| US11447494B2 (en) | 2019-05-01 | 2022-09-20 | Incyte Corporation | Tricyclic amine compounds as CDK2 inhibitors |
| MX2022001940A (es) | 2019-08-14 | 2022-05-10 | Incyte Corp | Compuestos de imidazolil pirimidinilamina como inhibidores de cdk2. |
| CN119930610A (zh) | 2019-10-11 | 2025-05-06 | 因赛特公司 | 作为cdk2抑制剂的双环胺 |
| US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
| US11976073B2 (en) | 2021-12-10 | 2024-05-07 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11505524A (ja) | 1995-05-01 | 1999-05-21 | 藤沢薬品工業株式会社 | イミダゾ１，２−ａピリジンおよびイミダゾ１，２−ａピリデジン誘導体、および骨吸収阻害剤としてのその用途 |
| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
| HU229024B1 (en) | 1996-07-24 | 2013-07-29 | Bristol Myers Squibb Pharma Co | Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof |
| ES2273369T3 (es) | 1996-08-28 | 2007-05-01 | Pfizer Inc. | Derivados 6,5 heterobiciclicos sustituidos. |
| EP1023066A4 (de) * | 1997-06-13 | 2001-05-23 | Smithkline Beecham Corp | Neue pyrazole- und pyrazoline- substituierte verbindung |
| JP2000038350A (ja) | 1998-05-18 | 2000-02-08 | Yoshitomi Pharmaceut Ind Ltd | 糖尿病治療薬 |
| FR2779724B1 (fr) * | 1998-06-10 | 2001-04-20 | Rhone Poulenc Rorer Sa | Derives du pyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent |
| WO2000059907A2 (en) | 1999-04-06 | 2000-10-12 | Du Pont Pharmaceuticals Company | Pyrazolotriazines as crf antagonists |
| EP1218381B1 (de) | 1999-09-30 | 2006-12-06 | Neurogen Corporation | Amino-substituierte pyrazolo¬1,5-a|-1,5-pyrimidine und pyrazolo¬1,5-a|-1,3,5-triazine |
| JP2003510325A (ja) | 1999-09-30 | 2003-03-18 | ニューロジェン・コーポレーション | ある種のアルキレンジアミン−置換ピラゾロ［１，５−ａ］−１，５−ピリミジン及びピラゾロ［１，５−ａ］−１，３，５−トリアジン |
| GB0016787D0 (en) | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
| DE60112609T2 (de) | 2000-12-15 | 2006-01-19 | Glaxo Group Ltd., Greenford | Pyrazolopyridine |
| US7163940B2 (en) | 2000-12-15 | 2007-01-16 | Smithkline Beecham Corporation | Pyrazolopyridinyl pyrimidine therapeutic compounds |
| GB0103926D0 (en) | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| ES2227451T3 (es) | 2001-03-08 | 2005-04-01 | Smithkline Beecham Corporation | Derivados de pirazolopiridina. |
| JP2004525150A (ja) * | 2001-03-30 | 2004-08-19 | スミスクライン ビーチャム コーポレーション | 治療用化合物としてのピラゾロピリジン類の使用 |
| JP4237497B2 (ja) | 2001-03-30 | 2009-03-11 | スミスクライン ビーチャム コーポレーション | ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用 |
| WO2002083672A1 (en) | 2001-04-10 | 2002-10-24 | Smithkline Beecham Corporation | Antiviral pyrazolopyridine compounds |
| EP1385847B1 (de) | 2001-04-27 | 2005-06-01 | SmithKline Beecham Corporation | Pyrazolo[1,5]pyridinderivate |
| IL158667A0 (en) | 2001-06-21 | 2004-05-12 | Smithkline Beecham Corp | Imidazo [1,2-a] pyridine derivatives for the prophylaxis and treatment of herpes viral infections |
| EP1423389B1 (de) | 2001-09-07 | 2007-06-06 | SmithKline Beecham Corporation | Pyrazolo-pyridine für die behandlung von herpes-ansteckungen |
| ES2262893T3 (es) | 2001-10-05 | 2006-12-01 | Smithkline Beecham Corporation | Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes. |
| US7199120B2 (en) | 2001-12-11 | 2007-04-03 | Smithkline Beecham Corporation | Pyrazolo-pyridine derivatives as antiherpes agents |
| ES2287476T3 (es) | 2002-05-10 | 2007-12-16 | Smithkline Beecham Corporation | Pirazolopirimidinas sustituidas. |
| US7153863B2 (en) | 2002-10-03 | 2006-12-26 | Smithkline Beecham Corporation | Therapeutic compounds based on pyrazolopyridline derivatives |
-
2003
- 2003-02-24 EP EP03713672A patent/EP1485385B1/de not_active Expired - Lifetime
- 2003-02-24 ES ES03713672T patent/ES2245772T3/es not_active Expired - Lifetime
- 2003-02-24 AT AT03713672T patent/ATE302203T1/de not_active IP Right Cessation
- 2003-02-24 JP JP2003574658A patent/JP2005525382A/ja active Pending
- 2003-02-24 AU AU2003217712A patent/AU2003217712A1/en not_active Abandoned
- 2003-02-24 DE DE60301339T patent/DE60301339T2/de not_active Expired - Fee Related
- 2003-02-24 WO PCT/US2003/005704 patent/WO2003076441A1/en not_active Ceased
- 2003-02-24 US US10/505,386 patent/US7247626B2/en not_active Expired - Fee Related
-
2007
- 2007-05-30 US US11/755,067 patent/US20070232623A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003217712A1 (en) | 2003-09-22 |
| US7247626B2 (en) | 2007-07-24 |
| EP1485385B1 (de) | 2005-08-17 |
| JP2005525382A (ja) | 2005-08-25 |
| ES2245772T3 (es) | 2006-01-16 |
| DE60301339T2 (de) | 2006-03-09 |
| US20070232623A1 (en) | 2007-10-04 |
| US20050124616A1 (en) | 2005-06-09 |
| DE60301339D1 (de) | 2005-09-22 |
| WO2003076441A1 (en) | 2003-09-18 |
| EP1485385A1 (de) | 2004-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |