ATE30233T1 - Chemisches verfahren. - Google Patents

Chemisches verfahren.

Info

Publication number
ATE30233T1
ATE30233T1 AT83307446T AT83307446T ATE30233T1 AT E30233 T1 ATE30233 T1 AT E30233T1 AT 83307446 T AT83307446 T AT 83307446T AT 83307446 T AT83307446 T AT 83307446T AT E30233 T1 ATE30233 T1 AT E30233T1
Authority
AT
Austria
Prior art keywords
triones
indoline
substituted spiro
chemical process
unwanted
Prior art date
Application number
AT83307446T
Other languages
English (en)
Inventor
Geoffrey Robert Bedford
David Robert Brittain
Ronald Platt
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Application granted granted Critical
Publication of ATE30233T1 publication Critical patent/ATE30233T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Storage Of Web-Like Or Filamentary Materials (AREA)
  • Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
AT83307446T 1982-12-20 1983-12-07 Chemisches verfahren. ATE30233T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8236969 1982-12-20
EP83307446A EP0115679B1 (de) 1982-12-20 1983-12-07 Chemisches Verfahren

Publications (1)

Publication Number Publication Date
ATE30233T1 true ATE30233T1 (de) 1987-10-15

Family

ID=10535286

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83307446T ATE30233T1 (de) 1982-12-20 1983-12-07 Chemisches verfahren.

Country Status (21)

Country Link
EP (1) EP0115679B1 (de)
JP (1) JPS59118787A (de)
KR (1) KR840007407A (de)
AT (1) ATE30233T1 (de)
AU (1) AU567312B2 (de)
CA (1) CA1209148A (de)
CS (1) CS240986B2 (de)
DD (1) DD216935A5 (de)
DE (1) DE3374060D1 (de)
DK (1) DK579283A (de)
ES (1) ES528173A0 (de)
FI (1) FI834637A7 (de)
GB (1) GB8331194D0 (de)
GR (1) GR79707B (de)
HU (1) HU189824B (de)
IE (1) IE56288B1 (de)
NO (1) NO834687L (de)
NZ (1) NZ206619A (de)
PL (1) PL245203A1 (de)
PT (1) PT77848B (de)
ZA (1) ZA838930B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8415635D0 (en) * 1984-06-19 1984-07-25 Ici Plc Cyclic amides
TW200801011A (en) 2006-02-07 2008-01-01 Astrazeneca Ab New compounds II
US20090076049A1 (en) * 2006-02-07 2009-03-19 Astrazeneca Ab Novel Spiro [Imidazolidine-4, 3' -Indole] 2, 2', 5' (1H) Triones for Treatment of Conditions Associated with Vanilloid Receptor 1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3024231A (en) * 1959-02-11 1962-03-06 Spencer Chem Co Racemization of d- and l-isomers of alpha-amino-epsilon-carprolactam
GB1569486A (en) * 1976-12-22 1980-06-18 Merck & Co Inc Racemisationof 6-oxo-2-piperidine-carboxylic acid entantiomers
IE50332B1 (en) * 1979-11-13 1986-04-02 Ici Ltd 1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof
IE53102B1 (en) * 1981-05-12 1988-06-22 Ici Plc Pharmaceutical spiro-succinimide derivatives
GB8312379D0 (en) * 1983-05-05 1983-06-08 Ici Plc Heterocyclic compounds

Also Published As

Publication number Publication date
CS961283A2 (en) 1985-06-13
ZA838930B (en) 1985-04-24
AU2185283A (en) 1984-06-28
CS240986B2 (en) 1986-03-13
GR79707B (de) 1984-10-31
NZ206619A (en) 1986-09-10
IE56288B1 (en) 1991-06-05
CA1209148A (en) 1986-08-05
PT77848A (en) 1984-01-01
EP0115679A1 (de) 1984-08-15
DK579283A (da) 1984-06-21
IE832808L (en) 1984-06-20
JPS59118787A (ja) 1984-07-09
DK579283D0 (da) 1983-12-15
ES8600298A1 (es) 1985-10-01
EP0115679B1 (de) 1987-10-14
PL245203A1 (en) 1985-03-12
NO834687L (no) 1984-06-21
FI834637A7 (fi) 1984-06-21
AU567312B2 (en) 1987-11-19
KR840007407A (ko) 1984-12-07
DD216935A5 (de) 1985-01-02
ES528173A0 (es) 1985-10-01
PT77848B (en) 1986-07-11
GB8331194D0 (en) 1983-12-29
DE3374060D1 (en) 1987-11-19
FI834637A0 (fi) 1983-12-16
HU189824B (en) 1986-08-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee