ATE302755T1 - Salz des (2r,3r,4r)3,4-dihydroxy-2- hydroxymethylpyrrolidins - Google Patents

Salz des (2r,3r,4r)3,4-dihydroxy-2- hydroxymethylpyrrolidins

Info

Publication number
ATE302755T1
ATE302755T1 AT00909070T AT00909070T ATE302755T1 AT E302755 T1 ATE302755 T1 AT E302755T1 AT 00909070 T AT00909070 T AT 00909070T AT 00909070 T AT00909070 T AT 00909070T AT E302755 T1 ATE302755 T1 AT E302755T1
Authority
AT
Austria
Prior art keywords
hydroxymethylpyrrolidine
dihydroxy
salt
naphthalenesulfonate
preparation
Prior art date
Application number
AT00909070T
Other languages
English (en)
Inventor
Claus Ulrich Jessen
Petra Christine Lugstein
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE302755T1 publication Critical patent/ATE302755T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT00909070T 1999-03-15 2000-03-13 Salz des (2r,3r,4r)3,4-dihydroxy-2- hydroxymethylpyrrolidins ATE302755T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199900362 1999-03-15
PCT/DK2000/000105 WO2000055132A1 (en) 1999-03-15 2000-03-13 New salt of (2r,3r,4r)-3,4-dihydroxy-2-hydroxymethylpyrrolidine

Publications (1)

Publication Number Publication Date
ATE302755T1 true ATE302755T1 (de) 2005-09-15

Family

ID=8092666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00909070T ATE302755T1 (de) 1999-03-15 2000-03-13 Salz des (2r,3r,4r)3,4-dihydroxy-2- hydroxymethylpyrrolidins

Country Status (6)

Country Link
EP (1) EP1163218B1 (de)
JP (1) JP2002539195A (de)
AT (1) ATE302755T1 (de)
AU (1) AU3147900A (de)
DE (1) DE60022172D1 (de)
WO (1) WO2000055132A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ533360A (en) 2004-06-04 2007-02-23 Ind Res Ltd Improved method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL124109A (en) * 1995-09-08 2001-10-31 Novo Nordisk As Pharmaceutical composition of 2-alkylpyrrolidines for use in the manufacture of medicaments for the treatment of diabetes

Also Published As

Publication number Publication date
JP2002539195A (ja) 2002-11-19
DE60022172D1 (de) 2005-09-29
AU3147900A (en) 2000-10-04
EP1163218A1 (de) 2001-12-19
WO2000055132A1 (en) 2000-09-21
EP1163218B1 (de) 2005-08-24

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties