ATE305776T1 - Derivate von triterpen-säuren - Google Patents
Derivate von triterpen-säurenInfo
- Publication number
- ATE305776T1 ATE305776T1 AT01934139T AT01934139T ATE305776T1 AT E305776 T1 ATE305776 T1 AT E305776T1 AT 01934139 T AT01934139 T AT 01934139T AT 01934139 T AT01934139 T AT 01934139T AT E305776 T1 ATE305776 T1 AT E305776T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- derivatives
- relates
- present
- Prior art date
Links
- -1 TRITERPENE ACIDS Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0012526A GB2362648A (en) | 2000-05-23 | 2000-05-23 | Triterpenoid derivatives |
| PCT/GB2001/002313 WO2001090136A2 (en) | 2000-05-23 | 2001-05-23 | Triterpenoid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE305776T1 true ATE305776T1 (de) | 2005-10-15 |
Family
ID=9892207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01934139T ATE305776T1 (de) | 2000-05-23 | 2001-05-23 | Derivate von triterpen-säuren |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7041701B2 (de) |
| EP (1) | EP1294370B1 (de) |
| AT (1) | ATE305776T1 (de) |
| AU (1) | AU2001260445A1 (de) |
| DE (1) | DE60113838T2 (de) |
| ES (1) | ES2250406T3 (de) |
| GB (1) | GB2362648A (de) |
| WO (1) | WO2001090136A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
| US6720445B2 (en) * | 2000-12-21 | 2004-04-13 | Beacon Laboratories, Inc. | Acetyloxymethyl esters and methods for using the same |
| GB0128071D0 (en) | 2001-11-22 | 2002-01-16 | Cyclacel Ltd | Medicament |
| JPWO2003057224A1 (ja) * | 2001-12-28 | 2005-08-25 | 日清オイリオグループ株式会社 | アポトーシス誘導剤 |
| ATE502931T1 (de) | 2004-08-19 | 2011-04-15 | Dsm Ip Assets Bv | Verfahren zur rektifikation von vitamin e acetat |
| GB0419416D0 (en) * | 2004-09-01 | 2004-10-06 | Inst Of Ex Botany Ascr | 4-Arylazo-3,5-Diamino-Pyrazole compounds and use thereof |
| CZ300722B6 (cs) * | 2006-09-27 | 2009-07-22 | Univerzita Karlova v Praze, Prírodovedecká fakulta | Zpusob prípravy inkluzního komplexu pentacyklických a tetracyklických terpenoidu a farmaceutického prostredku obsahujícího tento inkluzní komplex, inkluzní komplex pentacyklického nebo tetracyklického terpenoidu a farmaceutický prostredek obsahující |
| WO2009058849A1 (en) * | 2007-10-29 | 2009-05-07 | University Of Rochester | Use of electrophilic compounds for inducing platelet production or maintaining platelet function |
| JP5320530B2 (ja) * | 2008-02-14 | 2013-10-23 | 秋田県 | 抗癌剤として有用なトリテルペン化合物及び該トリテルペン化合物を用いた抗癌用組成物 |
| CZ301158B6 (cs) * | 2008-09-01 | 2009-11-18 | Univerzita Karlova v Praze, Prírodovedecká fakulta | Deriváty triterpenoidu pro lécbu nádorových onemocnení a farmaceutická kompozice je obsahující |
| CZ301318B6 (cs) | 2008-11-13 | 2010-01-13 | Univerzita Palackého v Olomouci | 2-Deoxyglykosidy triterpenoidu, zpusob jejich prípravy a jejich použití jako lécivo |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2810758A (en) * | 1955-05-26 | 1957-10-22 | Wisconsin Alumni Res Found | Steroid and intermediate compounds |
| CH602794A5 (de) * | 1974-10-29 | 1978-08-15 | Hoffmann La Roche | |
| IL50854A (en) * | 1975-11-11 | 1979-12-30 | Sparamedica Ag | D-homosteroids their manufacture and pharmaceutical compositions containing them |
| US5869535A (en) | 1995-03-21 | 1999-02-09 | The Board Of Trustees Of The University Of Illinois | Method and composition for selectively inhibiting melanoma |
| US6048847A (en) * | 1997-09-30 | 2000-04-11 | Dabur Research Foundation | Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this |
-
2000
- 2000-05-23 GB GB0012526A patent/GB2362648A/en not_active Withdrawn
-
2001
- 2001-05-23 ES ES01934139T patent/ES2250406T3/es not_active Expired - Lifetime
- 2001-05-23 AT AT01934139T patent/ATE305776T1/de not_active IP Right Cessation
- 2001-05-23 AU AU2001260445A patent/AU2001260445A1/en not_active Abandoned
- 2001-05-23 DE DE60113838T patent/DE60113838T2/de not_active Expired - Lifetime
- 2001-05-23 WO PCT/GB2001/002313 patent/WO2001090136A2/en not_active Ceased
- 2001-05-23 EP EP01934139A patent/EP1294370B1/de not_active Expired - Lifetime
- 2001-05-23 US US10/296,457 patent/US7041701B2/en not_active Expired - Fee Related
-
2006
- 2006-03-17 US US11/378,228 patent/US7749988B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001090136A2 (en) | 2001-11-29 |
| EP1294370B1 (de) | 2005-10-05 |
| EP1294370A2 (de) | 2003-03-26 |
| US7749988B2 (en) | 2010-07-06 |
| US7041701B2 (en) | 2006-05-09 |
| ES2250406T3 (es) | 2006-04-16 |
| DE60113838D1 (de) | 2006-02-16 |
| GB0012526D0 (en) | 2000-07-12 |
| WO2001090136A3 (en) | 2003-01-16 |
| US20060160890A1 (en) | 2006-07-20 |
| DE60113838T2 (de) | 2006-06-08 |
| US20040266868A1 (en) | 2004-12-30 |
| GB2362648A (en) | 2001-11-28 |
| AU2001260445A1 (en) | 2001-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1294370 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |