ATE306251T1 - Verwendung eines biologisch abbaubaren polymers - Google Patents

Verwendung eines biologisch abbaubaren polymers

Info

Publication number
ATE306251T1
ATE306251T1 AT00916536T AT00916536T ATE306251T1 AT E306251 T1 ATE306251 T1 AT E306251T1 AT 00916536 T AT00916536 T AT 00916536T AT 00916536 T AT00916536 T AT 00916536T AT E306251 T1 ATE306251 T1 AT E306251T1
Authority
AT
Austria
Prior art keywords
biodegradable polymer
solid tumor
phosphoester
mammal
inhibit
Prior art date
Application number
AT00916536T
Other languages
English (en)
Inventor
Wenbin Dang
Robert I Garver Jr
Original Assignee
Guilford Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guilford Pharm Inc filed Critical Guilford Pharm Inc
Application granted granted Critical
Publication of ATE306251T1 publication Critical patent/ATE306251T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT00916536T 1999-03-26 2000-03-20 Verwendung eines biologisch abbaubaren polymers ATE306251T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/276,866 US6537585B1 (en) 1999-03-26 1999-03-26 Methods and compositions for treating solid tumors
PCT/US2000/007304 WO2000057852A2 (en) 1999-03-26 2000-03-20 Methods and compositions for treating solid tumors

Publications (1)

Publication Number Publication Date
ATE306251T1 true ATE306251T1 (de) 2005-10-15

Family

ID=23058398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00916536T ATE306251T1 (de) 1999-03-26 2000-03-20 Verwendung eines biologisch abbaubaren polymers

Country Status (17)

Country Link
US (2) US6537585B1 (de)
EP (1) EP1185249B1 (de)
JP (2) JP2002540137A (de)
KR (1) KR20010111578A (de)
CN (1) CN1367684A (de)
AT (1) ATE306251T1 (de)
AU (1) AU778279B2 (de)
BR (1) BR0009213A (de)
CA (1) CA2368621C (de)
CZ (1) CZ20013260A3 (de)
DE (1) DE60023138T2 (de)
HU (1) HUP0201436A3 (de)
IL (1) IL145492A0 (de)
NO (1) NO20014662L (de)
PL (1) PL351280A1 (de)
TR (1) TR200102801T2 (de)
WO (1) WO2000057852A2 (de)

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Also Published As

Publication number Publication date
TR200102801T2 (tr) 2002-04-22
NO20014662D0 (no) 2001-09-25
PL351280A1 (en) 2003-04-07
US6537585B1 (en) 2003-03-25
WO2000057852A2 (en) 2000-10-05
BR0009213A (pt) 2002-04-16
JP2002540137A (ja) 2002-11-26
US20030203033A1 (en) 2003-10-30
EP1185249B1 (de) 2005-10-12
CA2368621C (en) 2010-05-25
NO20014662L (no) 2001-11-20
DE60023138T2 (de) 2006-08-17
HUP0201436A2 (en) 2002-09-28
CA2368621A1 (en) 2000-10-05
DE60023138D1 (de) 2006-02-23
AU778279B2 (en) 2004-11-25
KR20010111578A (ko) 2001-12-19
HUP0201436A3 (en) 2003-04-28
US7101568B2 (en) 2006-09-05
CZ20013260A3 (cs) 2002-01-16
EP1185249A2 (de) 2002-03-13
AU3762500A (en) 2000-10-16
IL145492A0 (en) 2002-06-30
JP2011219483A (ja) 2011-11-04
CN1367684A (zh) 2002-09-04
WO2000057852A3 (en) 2001-02-15

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