TR200103151T2 - Karboksipeptidaz U inhibitörü ile trombin inhibitörünü içeren farmasötik bir formülasyon. - Google Patents

Karboksipeptidaz U inhibitörü ile trombin inhibitörünü içeren farmasötik bir formülasyon.

Info

Publication number
TR200103151T2
TR200103151T2 TR2001/03151T TR200103151T TR200103151T2 TR 200103151 T2 TR200103151 T2 TR 200103151T2 TR 2001/03151 T TR2001/03151 T TR 2001/03151T TR 200103151 T TR200103151 T TR 200103151T TR 200103151 T2 TR200103151 T2 TR 200103151T2
Authority
TR
Turkey
Prior art keywords
inhibitor
carboxypeptidase
thrombin
pharmaceutical formulation
formulation containing
Prior art date
Application number
TR2001/03151T
Other languages
English (en)
Inventor
Abrahamsson Tommy
Nerme Viveca
Polla Magnus
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9901572A external-priority patent/SE9901572D0/xx
Priority claimed from SE9901573A external-priority patent/SE9901573D0/xx
Priority claimed from SE9902902A external-priority patent/SE9902902D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200103151T2 publication Critical patent/TR200103151T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Mevcut bulus karboksipeptidaz U (CPU) inhibitörü ile bir trombin inhibitörünü farmasötik olarak kabul edilen katki maddeleri, sulandiricilar ve tasiyicilarla beraber karisim halde içeren farmasötik formülasyonlar, ayni zamanda bir parça takimini, bir tedavi yöntemi ve CPU' nun inhibisyonunun ve/veya trombin inhibisyonunun gerekli oldugu ya da istendigi bir durumun tedavisine yönelik bir kullanimla ilgilidir.
TR2001/03151T 1999-05-03 2000-05-03 Karboksipeptidaz U inhibitörü ile trombin inhibitörünü içeren farmasötik bir formülasyon. TR200103151T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9901572A SE9901572D0 (sv) 1999-05-03 1999-05-03 New compounds
SE9901573A SE9901573D0 (sv) 1999-05-03 1999-05-03 New compounds
SE9902902A SE9902902D0 (sv) 1999-08-13 1999-08-13 New formulation

Publications (1)

Publication Number Publication Date
TR200103151T2 true TR200103151T2 (tr) 2002-04-22

Family

ID=27355973

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03151T TR200103151T2 (tr) 1999-05-03 2000-05-03 Karboksipeptidaz U inhibitörü ile trombin inhibitörünü içeren farmasötik bir formülasyon.

Country Status (26)

Country Link
US (1) US6974800B1 (tr)
EP (1) EP1181048B1 (tr)
JP (1) JP2002543148A (tr)
KR (1) KR100725206B1 (tr)
CN (1) CN100518820C (tr)
AR (1) AR023819A1 (tr)
AT (1) ATE447964T1 (tr)
AU (1) AU763772B2 (tr)
BR (1) BR0010255A (tr)
CA (1) CA2371217A1 (tr)
CZ (1) CZ20013932A3 (tr)
DE (1) DE60043297D1 (tr)
EE (1) EE200100578A (tr)
ES (1) ES2335383T3 (tr)
HK (1) HK1042442B (tr)
HU (1) HUP0201615A3 (tr)
IL (1) IL145951A0 (tr)
IS (1) IS6140A (tr)
MX (1) MXPA01011044A (tr)
MY (1) MY126962A (tr)
NO (1) NO20015308L (tr)
NZ (1) NZ515063A (tr)
SK (1) SK15652001A3 (tr)
TR (1) TR200103151T2 (tr)
TW (1) TWI232106B (tr)
WO (1) WO2000066152A1 (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901572D0 (sv) * 1999-05-03 1999-05-03 Astra Ab New compounds
WO2001019836A1 (en) 1999-09-14 2001-03-22 Meiji Seika Kaisha, Ltd. Phosphonic acid derivatives having carboxypeptidase b inhibitory activity
SE0001803D0 (sv) 2000-05-16 2000-05-16 Astrazeneca Ab New compounds i
SE0103272D0 (sv) 2001-09-28 2001-09-28 Astrazeneca Ab Chemical compounds
CA2472239A1 (en) 2002-01-22 2003-07-31 Pfizer Inc. 3-(imidazolyl)-2-aminopropanoic acids for use as tafi-a inhibitors for the treatment of thrombotic diseases
US6713496B2 (en) 2002-01-22 2004-03-30 Pfizer Inc 3-(imidazolyl)-2-alkoxypropanoic acids
KR100972717B1 (ko) 2002-03-21 2010-07-27 바이엘 쉐링 파마 악티엔게젤샤프트 혈장 카르복시펩티드분해효소 ｂ 억제제
ZA200800251B (en) * 2005-06-24 2009-04-29 Drugrecure Aps Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory track
RU2015156612A (ru) 2013-06-10 2017-07-17 Санофи Макроциклические производные мочевины в качестве ингибиторов tafia, их получение и их применение в качестве фармацевтических средств
EP3569617A1 (en) * 2018-05-18 2019-11-20 Trion Research GmbH Pharmaceutical preparation for use in treating epstein- barr virus positive patients with reactivation phenomenon- associated diseases

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3091569A (en) 1960-08-26 1963-05-28 Mead Johnson & Co Mucolytic-nu-acylated sulfhydryl compositions and process for treating animal mucus
FR1393338A (fr) 1964-01-08 1965-03-26 Rech S Pharma Et Scient Nouveau dérivé de la cystéine et sa préparation
US3766206A (en) 1971-11-03 1973-10-16 Pfizer 18beta-glycyrrheting acid amides useful as antiulcer agents
FR2266502A1 (en) 1974-04-08 1975-10-31 Synpharm Sa N-(2-thenoyl)-cysteine and esters - with mucolytic activity, prepd. from cysteine (esters) and thenoyl chloride
US4113715A (en) 1977-01-17 1978-09-12 E. R. Squibb & Sons, Inc. Amino acid derivatives
US4177277A (en) * 1977-01-17 1979-12-04 E. R. Squibb & Sons, Inc. Method for alleviating hypertension
JPS545949A (en) 1977-06-16 1979-01-17 Hisamitsu Pharmaceut Co Inc Novel cyclohexanecarboxylic acid and its derivatives
FR2430945A2 (fr) 1978-07-12 1980-02-08 Chauvin Blache Lab Nouveaux derives de la cysteine, leur procede de fabrication et leur application en therapeutique
US4708965A (en) 1985-09-16 1987-11-24 Morgan Lee R Method of treating herpes virus infections with N,N'-diacetylcystine and derivatives
DE3838467C2 (de) 1988-11-12 1998-12-10 Agfa Gevaert Ag Fotografisches Aufzeichnungsmaterial
US5206161A (en) * 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
IT1249650B (it) 1991-05-29 1995-03-09 Poli Ind Chimica Spa N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
SE9404196D0 (sv) * 1994-12-02 1994-12-02 Astra Ab New antithrombotic formulation
KR0173034B1 (ko) 1995-04-28 1999-03-30 성재갑 선택적 트롬빈 억제제
GB9525620D0 (en) * 1995-12-15 1996-02-14 Glaxo Group Ltd Chemical compounds
US5859271A (en) * 1996-04-15 1999-01-12 Virginia Commonwealth University Cytoprotective compounds
US6126939A (en) * 1996-09-03 2000-10-03 Yeda Research And Development Co. Ltd. Anti-inflammatory dipeptide and pharmaceutical composition thereof
US5993815A (en) * 1996-11-08 1999-11-30 University Of Vermont Methods and compositions for inhibiting the activation of thrombin-activatable fibrinolysis inhibitor (TAFI)
WO1998046588A2 (en) * 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies

Also Published As

Publication number Publication date
IL145951A0 (en) 2002-07-25
NO20015308D0 (no) 2001-10-30
EP1181048A1 (en) 2002-02-27
EP1181048B1 (en) 2009-11-11
CZ20013932A3 (cs) 2002-04-17
MY126962A (en) 2006-11-30
HUP0201615A3 (en) 2006-07-28
EE200100578A (et) 2003-02-17
HK1042442B (en) 2010-04-09
AU4447200A (en) 2000-11-17
CA2371217A1 (en) 2000-11-02
AU763772B2 (en) 2003-07-31
KR100725206B1 (ko) 2007-06-07
HUP0201615A2 (en) 2002-09-28
SK15652001A3 (sk) 2002-07-02
BR0010255A (pt) 2002-02-13
MXPA01011044A (es) 2002-06-04
KR20020003386A (ko) 2002-01-12
JP2002543148A (ja) 2002-12-17
PL356119A1 (en) 2004-06-14
AR023819A1 (es) 2002-09-04
ATE447964T1 (de) 2009-11-15
HK1042442A1 (en) 2002-08-16
TWI232106B (en) 2005-05-11
NO20015308L (no) 2001-12-03
CN1350463A (zh) 2002-05-22
ES2335383T3 (es) 2010-03-26
IS6140A (is) 2001-11-01
NZ515063A (en) 2003-08-29
US6974800B1 (en) 2005-12-13
DE60043297D1 (de) 2009-12-24
CN100518820C (zh) 2009-07-29
WO2000066152A1 (en) 2000-11-09

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