ATE308343T1 - Trägerhilfstoff - Google Patents
TrägerhilfstoffInfo
- Publication number
- ATE308343T1 ATE308343T1 AT99929812T AT99929812T ATE308343T1 AT E308343 T1 ATE308343 T1 AT E308343T1 AT 99929812 T AT99929812 T AT 99929812T AT 99929812 T AT99929812 T AT 99929812T AT E308343 T1 ATE308343 T1 AT E308343T1
- Authority
- AT
- Austria
- Prior art keywords
- carrier aid
- aid
- carrier
- whiteness
- trehalose
- Prior art date
Links
- 239000002245 particle Substances 0.000 abstract 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Glass Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20029598 | 1998-07-15 | ||
| JP32356098 | 1998-11-13 | ||
| PCT/JP1999/003775 WO2000003735A1 (fr) | 1998-07-15 | 1999-07-13 | Excipient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE308343T1 true ATE308343T1 (de) | 2005-11-15 |
Family
ID=26512084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99929812T ATE308343T1 (de) | 1998-07-15 | 1999-07-13 | Trägerhilfstoff |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6699845B2 (de) |
| EP (1) | EP1097722B1 (de) |
| JP (1) | JP4748627B2 (de) |
| KR (1) | KR100421264B1 (de) |
| CN (1) | CN1185013C (de) |
| AT (1) | ATE308343T1 (de) |
| AU (1) | AU743109B2 (de) |
| CA (1) | CA2337015C (de) |
| DE (1) | DE69928110T2 (de) |
| WO (1) | WO2000003735A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US20040131672A1 (en) * | 2003-01-07 | 2004-07-08 | Nilobon Podhipleux | Direct compression pharmaceutical composition containing a pharmaceutically active ingredient with poor flowing properties |
| EP1460080A1 (de) * | 2003-03-21 | 2004-09-22 | Cargill Incorporated | Direkt komprimierbare Trehalose in fester Form |
| WO2004084650A1 (ja) * | 2003-03-26 | 2004-10-07 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | 非糖質成分の粉末化方法及び粉末化基剤 |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| JP2007131587A (ja) * | 2005-11-11 | 2007-05-31 | Activas Pharma:Kk | キノリノン誘導体を有効成分とする医薬組成物、及びその製造方法 |
| UA92052C2 (ru) * | 2005-12-07 | 2010-09-27 | Нікомед Фарма Ас | Предварительно уплотненные кальциесодержащие композиции |
| CN100391541C (zh) * | 2006-03-16 | 2008-06-04 | 南台科技大学 | 以胶质类食材制造赋形剂的方法 |
| CN101460150B (zh) * | 2006-03-31 | 2014-02-12 | 鲁比康研究私人有限公司 | 用于口腔崩解片剂的可直接压片复合物 |
| EP2540725A1 (de) | 2006-05-04 | 2013-01-02 | Boehringer Ingelheim International GmbH | Polymorphe von 1-((4-Methyl-chinazolin-2-yl)methyl)-3-methyl-7-(2-butin-1-yl)-8-(3-(R)-amino-piperidin-1-yl)xanthin |
| EP1852108A1 (de) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Zusammensetzungen von DPP-IV-Inhibitoren |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| JP5769362B2 (ja) * | 2006-06-27 | 2015-08-26 | 第一三共株式会社 | 圧縮製剤 |
| WO2008079342A2 (en) * | 2006-12-21 | 2008-07-03 | Mallinckrodt Inc. | Composition of and method for preparing orally disintegrating tablets |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| JP5344938B2 (ja) * | 2009-01-29 | 2013-11-20 | 旭化成ケミカルズ株式会社 | 崩壊性固形製剤 |
| KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| CN102946875A (zh) | 2010-05-05 | 2013-02-27 | 贝林格尔.英格海姆国际有限公司 | 组合疗法 |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| ES2674599T3 (es) * | 2011-09-21 | 2018-07-02 | Hayashibara Co., Ltd. | Proceso para producir un polvo que contiene dihidrato de alfa,alfa-trehalosa cristalino |
| US9522964B2 (en) * | 2012-04-03 | 2016-12-20 | Development, Inc. | Micronized starch and methods for manufacturing same |
| JP6218811B2 (ja) | 2012-05-14 | 2017-10-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｓｉｒｓ及び／又は敗血症の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体 |
| JP6224084B2 (ja) | 2012-05-14 | 2017-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体 |
| CN109310697A (zh) | 2016-06-10 | 2019-02-05 | 勃林格殷格翰国际有限公司 | 利格列汀和二甲双胍的组合 |
| WO2019069490A1 (ja) | 2017-10-03 | 2019-04-11 | 株式会社Ｍｉｚｋａｎ Ｈｏｌｄｉｎｇｓ | 食品微粒子複合体含有組成物及びその製造法 |
| KR20210052281A (ko) | 2019-10-29 | 2021-05-10 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 캡슐 충전용 조성물 및 이것을 사용한 캡슐 제제의 제조 방법 그리고 캡슐 제제 |
| KR102848723B1 (ko) | 2025-04-18 | 2025-08-21 | 주식회사 탑시스템 | 축전부의 방열을 위한 대면적 히트싱크를 갖는 태양광 발전부가 구비된 가로등 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4762857A (en) | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| US4678812A (en) | 1986-05-30 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| ATE216577T1 (de) | 1992-01-29 | 2002-05-15 | Takeda Chemical Industries Ltd | Schnellösliche tablette und ihre herstellung |
| US5837285A (en) | 1992-02-18 | 1998-11-17 | Nakamichi; Kouichi | Fast soluble tablet |
| JPH069382A (ja) * | 1992-04-17 | 1994-01-18 | Takeda Chem Ind Ltd | 安定化された固型製剤およびその製造方法 |
| ATE182359T1 (de) | 1992-12-28 | 1999-08-15 | Hayashibara Biochem Lab | Nichtreduzierendes saccharidbildendes enzym, und dessen herstellung und verwendungen |
| JP3773062B2 (ja) * | 1993-01-29 | 2006-05-10 | 味の素株式会社 | 製剤用添加剤 |
| JP3559585B2 (ja) * | 1993-06-03 | 2004-09-02 | 株式会社林原生物化学研究所 | トレハロース遊離酵素とその製造方法並びに用途 |
| ATE253899T1 (de) | 1994-01-31 | 2003-11-15 | Yamanouchi Pharma Co Ltd | Intraoral löslicher formpressling und verfahren zu seiner herstellung |
| JP3534130B2 (ja) * | 1994-03-01 | 2004-06-07 | 旭化成ケミカルズ株式会社 | 医薬品組成物 |
| IL114030A (en) * | 1994-06-27 | 2000-08-13 | Hayashibara Biochem Lab | Saccharide composition with a lesser reducibility its preparation and compositions containing it |
| JP3616166B2 (ja) | 1994-07-19 | 2005-02-02 | 株式会社林原生物化学研究所 | トレハロースとその製造方法並びに用途 |
| JP2919771B2 (ja) | 1995-04-17 | 1999-07-19 | 佐藤製薬株式会社 | 速溶解性錠剤の製造方法及び該製造方法により製造した速溶解性錠剤 |
| JP3418274B2 (ja) | 1995-06-05 | 2003-06-16 | 日本化薬株式会社 | 口腔内感触の良好な錠剤 |
| JPH0948726A (ja) | 1995-08-07 | 1997-02-18 | Tanabe Seiyaku Co Ltd | 口腔内速崩壊性製剤およびその製法 |
| CN1167436A (zh) | 1995-09-07 | 1997-12-10 | 大制药株式会社 | 低压泡滕片剂 |
| JP3624038B2 (ja) * | 1995-12-11 | 2005-02-23 | 株式会社林原生物化学研究所 | 糖衣固形物及びその製造方法 |
| EP0879048B2 (de) * | 1996-02-09 | 2009-07-29 | Quadrant Drug Delivery Limited | Verfahren zur Herstellung von Tabletten mit Hilfe von Trehalose |
| JPH09316006A (ja) | 1996-05-29 | 1997-12-09 | Yatsuken:Kk | 口腔内溶解性固形製剤 |
| JP3797387B2 (ja) | 1996-06-14 | 2006-07-19 | 協和醗酵工業株式会社 | 口腔内速崩壊錠 |
| GB9616536D0 (en) * | 1996-08-06 | 1996-09-25 | Quadrant Holdings Cambridge | Co-amoxiclav dosage form |
| TW527195B (en) * | 1997-10-09 | 2003-04-11 | Ssp Co Ltd | Fast-soluble solid pharmaceutical combinations |
| JPH11116464A (ja) | 1997-10-09 | 1999-04-27 | Ss Pharmaceut Co Ltd | 迅速溶解性固形製剤およびその製造法 |
-
1999
- 1999-07-13 CA CA002337015A patent/CA2337015C/en not_active Expired - Lifetime
- 1999-07-13 JP JP2000559869A patent/JP4748627B2/ja not_active Expired - Lifetime
- 1999-07-13 AT AT99929812T patent/ATE308343T1/de not_active IP Right Cessation
- 1999-07-13 KR KR10-2001-7000538A patent/KR100421264B1/ko not_active Expired - Lifetime
- 1999-07-13 EP EP99929812A patent/EP1097722B1/de not_active Expired - Lifetime
- 1999-07-13 WO PCT/JP1999/003775 patent/WO2000003735A1/ja not_active Ceased
- 1999-07-13 CN CNB998086274A patent/CN1185013C/zh not_active Expired - Lifetime
- 1999-07-13 AU AU46516/99A patent/AU743109B2/en not_active Expired
- 1999-07-13 DE DE69928110T patent/DE69928110T2/de not_active Expired - Lifetime
-
2001
- 2001-01-12 US US09/759,104 patent/US6699845B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1185013C (zh) | 2005-01-19 |
| DE69928110T2 (de) | 2006-07-27 |
| US6699845B2 (en) | 2004-03-02 |
| CN1309570A (zh) | 2001-08-22 |
| JP4748627B2 (ja) | 2011-08-17 |
| AU4651699A (en) | 2000-02-07 |
| KR100421264B1 (ko) | 2004-03-18 |
| EP1097722B1 (de) | 2005-11-02 |
| WO2000003735A1 (fr) | 2000-01-27 |
| CA2337015A1 (en) | 2000-01-27 |
| EP1097722A1 (de) | 2001-05-09 |
| CA2337015C (en) | 2004-09-07 |
| DE69928110D1 (de) | 2005-12-08 |
| US20020042393A1 (en) | 2002-04-11 |
| KR20010071883A (ko) | 2001-07-31 |
| AU743109B2 (en) | 2002-01-17 |
| EP1097722A4 (de) | 2002-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |