ATE308343T1 - Trägerhilfstoff - Google Patents
TrägerhilfstoffInfo
- Publication number
- ATE308343T1 ATE308343T1 AT99929812T AT99929812T ATE308343T1 AT E308343 T1 ATE308343 T1 AT E308343T1 AT 99929812 T AT99929812 T AT 99929812T AT 99929812 T AT99929812 T AT 99929812T AT E308343 T1 ATE308343 T1 AT E308343T1
- Authority
- AT
- Austria
- Prior art keywords
- carrier aid
- aid
- carrier
- whiteness
- trehalose
- Prior art date
Links
- 239000002245 particle Substances 0.000 abstract 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Glass Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Detergent Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20029598 | 1998-07-15 | ||
| JP32356098 | 1998-11-13 | ||
| PCT/JP1999/003775 WO2000003735A1 (fr) | 1998-07-15 | 1999-07-13 | Excipient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE308343T1 true ATE308343T1 (de) | 2005-11-15 |
Family
ID=26512084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99929812T ATE308343T1 (de) | 1998-07-15 | 1999-07-13 | Trägerhilfstoff |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6699845B2 (de) |
| EP (1) | EP1097722B1 (de) |
| JP (1) | JP4748627B2 (de) |
| KR (1) | KR100421264B1 (de) |
| CN (1) | CN1185013C (de) |
| AT (1) | ATE308343T1 (de) |
| AU (1) | AU743109B2 (de) |
| CA (1) | CA2337015C (de) |
| DE (1) | DE69928110T2 (de) |
| WO (1) | WO2000003735A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US20040131672A1 (en) * | 2003-01-07 | 2004-07-08 | Nilobon Podhipleux | Direct compression pharmaceutical composition containing a pharmaceutically active ingredient with poor flowing properties |
| EP1460080A1 (de) * | 2003-03-21 | 2004-09-22 | Cargill Incorporated | Direkt komprimierbare Trehalose in fester Form |
| WO2004084650A1 (ja) * | 2003-03-26 | 2004-10-07 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | 非糖質成分の粉末化方法及び粉末化基剤 |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| JP2007131587A (ja) * | 2005-11-11 | 2007-05-31 | Activas Pharma:Kk | キノリノン誘導体を有効成分とする医薬組成物、及びその製造方法 |
| UA92052C2 (ru) * | 2005-12-07 | 2010-09-27 | Нікомед Фарма Ас | Предварительно уплотненные кальциесодержащие композиции |
| CN100391541C (zh) * | 2006-03-16 | 2008-06-04 | 南台科技大学 | 以胶质类食材制造赋形剂的方法 |
| NZ572106A (en) * | 2006-03-31 | 2010-12-24 | Rubicon Res Private Ltd | Directly compressible composite for orally disintegrating tablets |
| PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| MX2008014024A (es) | 2006-05-04 | 2008-11-14 | Boehringer Ingelheim Int | Formas poliformas. |
| EP1852108A1 (de) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Zusammensetzungen von DPP-IV-Inhibitoren |
| EP2033643A4 (de) * | 2006-06-27 | 2013-01-02 | Daiichi Sankyo Co Ltd | Komprimierte zubereitung |
| EP2101738A2 (de) * | 2006-12-21 | 2009-09-23 | Mallinckrodt Inc. | Zusammensetzung und verfahren zur herstellung von im mund zerfallenden tabletten |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| JP5344938B2 (ja) * | 2009-01-29 | 2013-11-20 | 旭化成ケミカルズ株式会社 | 崩壊性固形製剤 |
| EP2504002B1 (de) | 2009-11-27 | 2019-10-09 | Boehringer Ingelheim International GmbH | Behandlung von genotypisierten diabetes-patienten mit dpp-iv-hemmern wie etwa linagliptin |
| KR101927068B1 (ko) | 2010-05-05 | 2018-12-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법 |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| MX2018007700A (es) * | 2011-09-21 | 2023-01-26 | Hayashibara Co | Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina. |
| US9522964B2 (en) * | 2012-04-03 | 2016-12-20 | Development, Inc. | Micronized starch and methods for manufacturing same |
| ES2929025T3 (es) | 2012-05-14 | 2022-11-24 | Boehringer Ingelheim Int | Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia |
| US20130303462A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome |
| BR112018072401A2 (pt) | 2016-06-10 | 2019-02-19 | Boehringer Ingelheim International Gmbh | combinações de linagliptina e metformina |
| CA3056678C (en) | 2017-10-03 | 2021-07-20 | Mizkan Holdings Co., Ltd. | Composition containing fine food particulate complexes, and method for producing same |
| KR20210052281A (ko) * | 2019-10-29 | 2021-05-10 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 캡슐 충전용 조성물 및 이것을 사용한 캡슐 제제의 제조 방법 그리고 캡슐 제제 |
| KR102848723B1 (ko) | 2025-04-18 | 2025-08-21 | 주식회사 탑시스템 | 축전부의 방열을 위한 대면적 히트싱크를 갖는 태양광 발전부가 구비된 가로등 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4678812A (en) | 1986-05-30 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| US4762857A (en) | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| EP0553777B1 (de) | 1992-01-29 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
| DE627218T1 (de) | 1992-02-18 | 1995-08-24 | Nippon Shinyaku Co Ltd | Schnelllösliche tablette. |
| JPH069382A (ja) * | 1992-04-17 | 1994-01-18 | Takeda Chem Ind Ltd | 安定化された固型製剤およびその製造方法 |
| DE69332781T2 (de) | 1992-12-28 | 2004-02-12 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Reinigung von Trehalose |
| JP3773062B2 (ja) * | 1993-01-29 | 2006-05-10 | 味の素株式会社 | 製剤用添加剤 |
| JP3559585B2 (ja) * | 1993-06-03 | 2004-09-02 | 株式会社林原生物化学研究所 | トレハロース遊離酵素とその製造方法並びに用途 |
| NZ278678A (en) | 1994-01-31 | 1998-03-25 | Yamanouchi Pharma Co Ltd | Compressed moulded tablet with quick disintegration/dissolution in the mouth, mixture of low and high moldable saccharides as carriers |
| JP3534130B2 (ja) * | 1994-03-01 | 2004-06-07 | 旭化成ケミカルズ株式会社 | 医薬品組成物 |
| TW426737B (en) * | 1994-06-27 | 2001-03-21 | Hayashibara Biochem Lab | Saccharide composition with reduced reducibility, and preparation and uses thereof |
| JP3616166B2 (ja) | 1994-07-19 | 2005-02-02 | 株式会社林原生物化学研究所 | トレハロースとその製造方法並びに用途 |
| JP2919771B2 (ja) | 1995-04-17 | 1999-07-19 | 佐藤製薬株式会社 | 速溶解性錠剤の製造方法及び該製造方法により製造した速溶解性錠剤 |
| JP3418274B2 (ja) | 1995-06-05 | 2003-06-16 | 日本化薬株式会社 | 口腔内感触の良好な錠剤 |
| JPH0948726A (ja) | 1995-08-07 | 1997-02-18 | Tanabe Seiyaku Co Ltd | 口腔内速崩壊性製剤およびその製法 |
| CA2204599A1 (en) | 1995-09-07 | 1997-03-13 | Otsuka Pharmaceutical Co., Ltd. | Low-pressure tableted effervescent preparation |
| JP3624038B2 (ja) * | 1995-12-11 | 2005-02-23 | 株式会社林原生物化学研究所 | 糖衣固形物及びその製造方法 |
| DE69728857T3 (de) * | 1996-02-09 | 2010-02-18 | Quadrant Drug Delivery Ltd., Ruddington | Feste arzneimittel enthaltend trehalose |
| JPH09316006A (ja) | 1996-05-29 | 1997-12-09 | Yatsuken:Kk | 口腔内溶解性固形製剤 |
| DE69733476T2 (de) | 1996-06-14 | 2006-03-23 | Kyowa Hakko Kogyo Co., Ltd. | Im munde schnellzerfallende tablette |
| GB9616536D0 (en) * | 1996-08-06 | 1996-09-25 | Quadrant Holdings Cambridge | Co-amoxiclav dosage form |
| TW527195B (en) * | 1997-10-09 | 2003-04-11 | Ssp Co Ltd | Fast-soluble solid pharmaceutical combinations |
| JPH11116464A (ja) | 1997-10-09 | 1999-04-27 | Ss Pharmaceut Co Ltd | 迅速溶解性固形製剤およびその製造法 |
-
1999
- 1999-07-13 CN CNB998086274A patent/CN1185013C/zh not_active Expired - Lifetime
- 1999-07-13 DE DE69928110T patent/DE69928110T2/de not_active Expired - Lifetime
- 1999-07-13 AT AT99929812T patent/ATE308343T1/de not_active IP Right Cessation
- 1999-07-13 KR KR10-2001-7000538A patent/KR100421264B1/ko not_active Expired - Lifetime
- 1999-07-13 CA CA002337015A patent/CA2337015C/en not_active Expired - Lifetime
- 1999-07-13 WO PCT/JP1999/003775 patent/WO2000003735A1/ja not_active Ceased
- 1999-07-13 JP JP2000559869A patent/JP4748627B2/ja not_active Expired - Lifetime
- 1999-07-13 EP EP99929812A patent/EP1097722B1/de not_active Expired - Lifetime
- 1999-07-13 AU AU46516/99A patent/AU743109B2/en not_active Expired
-
2001
- 2001-01-12 US US09/759,104 patent/US6699845B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1309570A (zh) | 2001-08-22 |
| CA2337015C (en) | 2004-09-07 |
| AU4651699A (en) | 2000-02-07 |
| KR20010071883A (ko) | 2001-07-31 |
| EP1097722B1 (de) | 2005-11-02 |
| WO2000003735A1 (fr) | 2000-01-27 |
| US20020042393A1 (en) | 2002-04-11 |
| JP4748627B2 (ja) | 2011-08-17 |
| CN1185013C (zh) | 2005-01-19 |
| EP1097722A4 (de) | 2002-03-20 |
| EP1097722A1 (de) | 2001-05-09 |
| DE69928110D1 (de) | 2005-12-08 |
| DE69928110T2 (de) | 2006-07-27 |
| US6699845B2 (en) | 2004-03-02 |
| AU743109B2 (en) | 2002-01-17 |
| KR100421264B1 (ko) | 2004-03-18 |
| CA2337015A1 (en) | 2000-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |