ATE309271T1 - Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen - Google Patents
Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungenInfo
- Publication number
- ATE309271T1 ATE309271T1 AT97926514T AT97926514T ATE309271T1 AT E309271 T1 ATE309271 T1 AT E309271T1 AT 97926514 T AT97926514 T AT 97926514T AT 97926514 T AT97926514 T AT 97926514T AT E309271 T1 ATE309271 T1 AT E309271T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- binding protein
- prevention
- cna
- dna segments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1767896P | 1996-05-16 | 1996-05-16 | |
| PCT/US1997/008210 WO1997043314A2 (en) | 1996-05-16 | 1997-05-14 | Collagen binding protein compositions and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309271T1 true ATE309271T1 (de) | 2005-11-15 |
Family
ID=21783969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97926514T ATE309271T1 (de) | 1996-05-16 | 1997-05-14 | Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6288214B1 (de) |
| EP (1) | EP0950068B1 (de) |
| AT (1) | ATE309271T1 (de) |
| AU (1) | AU3126097A (de) |
| CA (1) | CA2255669A1 (de) |
| DE (1) | DE69734601T2 (de) |
| DK (1) | DK0950068T3 (de) |
| ES (1) | ES2252785T3 (de) |
| WO (1) | WO1997043314A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0950068B1 (de) * | 1996-05-16 | 2005-11-09 | THE TEXAS A&M UNIVERSITY SYSTEM | Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen |
| US6610293B1 (en) * | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US6692739B1 (en) * | 1998-08-31 | 2004-02-17 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| WO2000012132A1 (en) * | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| KR100644953B1 (ko) * | 1998-08-31 | 2006-11-10 | 인히비텍스, 인코포레이티드 | 다성분 백신 |
| US20020092987A1 (en) * | 1998-09-05 | 2002-07-18 | Taehee Cho | Photo detect device using quantum dots and materialization method thereof |
| US6908994B1 (en) | 1999-05-10 | 2005-06-21 | The Texas A&M University System | Collagen-binding proteins from enterococcal bacteria |
| ATE527275T1 (de) * | 1999-05-10 | 2011-10-15 | Texas A & M Univ Sys | Kollagen-bindende proteine von enterococcalen bakterien |
| WO2001009806A1 (en) | 1999-08-02 | 2001-02-08 | E-Mark Systems Inc. | Electronic settlement system, settlement device, and terminal |
| US20070077256A1 (en) * | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| EP1267930A4 (de) | 2000-03-17 | 2005-01-19 | Inhibitex Inc | Kreuzreaktive, verdrängende antikörper von kollagenbindeproteinen, identifizierungsverfahren und verwendung |
| GB0014907D0 (en) | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| WO2002072600A2 (en) * | 2001-01-26 | 2002-09-19 | Inhibitex, Inc. | Monoclonal antibodies to the clfa protein and method of use in treating or preventing infections |
| JP2002253712A (ja) * | 2001-03-02 | 2002-09-10 | Endo Mfg Co Ltd | ゴルフクラブ |
| EP1443957A4 (de) * | 2001-05-08 | 2005-10-12 | Texas A & M Univ Sys | Oberflächenproteine aus grampositiven bakterien mit hochkonservierten motiven sowie diese erkennende antikörper |
| US6835378B2 (en) | 2001-05-11 | 2004-12-28 | The Texas A&M University System University | Method and compositions for inhibiting thrombin-induced coagulation |
| CA2450939C (en) | 2001-06-15 | 2012-11-06 | The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and staphylococcus aureus |
| US7115264B2 (en) * | 2001-11-05 | 2006-10-03 | Inhibitex | Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections |
| US20030153026A1 (en) * | 2002-01-04 | 2003-08-14 | Javier Alarcon | Entrapped binding protein as biosensors |
| US6855556B2 (en) | 2002-01-04 | 2005-02-15 | Becton, Dickinson And Company | Binding protein as biosensors |
| US20030190320A1 (en) * | 2002-02-21 | 2003-10-09 | Pietro Speziale | Monoclonal antibodies that are cross-reactive against bacterial collagen binding proteins |
| US20040006209A1 (en) * | 2002-03-05 | 2004-01-08 | Patti Joseph M. | Monoclonal and polyclonal antibodies recognizing coagulase-negative staphylococcal proteins |
| US9296795B2 (en) * | 2003-03-07 | 2016-03-29 | Wyeth Holdings, Llc. | Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| JP4799557B2 (ja) * | 2004-06-09 | 2011-10-26 | ベクトン・ディキンソン・アンド・カンパニー | 多検体センサー |
| JP2008513406A (ja) | 2004-09-22 | 2008-05-01 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
| BRPI0606481A2 (pt) | 2005-01-20 | 2009-06-30 | Isconova Ab | composição de vacina compreendendo uma proteìna de ligação a fibronectina ou um peptìdeo de ligação a fibronectina |
| JP4726109B2 (ja) * | 2005-02-10 | 2011-07-20 | 昭和電工株式会社 | 皮膚外用剤、それを用いる皮膚有害微生物の付着予防方法及び増殖防止方法 |
| NZ560612A (en) * | 2005-02-14 | 2011-01-28 | Epitopix Llc | Polypeptides from staphylococcus aureus and methods of use |
| WO2006138627A2 (en) * | 2005-06-16 | 2006-12-28 | Inhibitex, Inc. | Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein |
| CN101227940A (zh) * | 2005-07-25 | 2008-07-23 | 纳米技术维多利亚有限公司 | 微阵列装置 |
| WO2007030012A2 (en) * | 2005-09-05 | 2007-03-15 | Stichting Voor De Technische Wetenscahappen | Extracellular matrix imaging |
| AU2007221321B2 (en) * | 2006-02-22 | 2012-06-28 | The Texas A & M University System | Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use |
| EP1998802A2 (de) | 2006-03-30 | 2008-12-10 | GlaxoSmithKline Biologicals S.A. | Immunogene zusammensetzung |
| EP2029799B1 (de) | 2006-04-20 | 2012-08-22 | Becton, Dickinson and Company | Thermisch stabile proteine und verfahren zu ihrer herstellung und verwendung |
| US20180221466A9 (en) * | 2006-06-12 | 2018-08-09 | Glaxosmithkline Biologicals S.A. | Use of alpha-toxin for treating and preventing staphylococcus infections |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| AU2008292897B2 (en) * | 2007-08-31 | 2015-01-22 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| US8758765B2 (en) * | 2008-07-29 | 2014-06-24 | The University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
| WO2010042481A1 (en) | 2008-10-06 | 2010-04-15 | University Of Chicago | Compositions and methods related to bacterial eap, emp, and/or adsa proteins |
| AU2010204139A1 (en) * | 2009-01-12 | 2011-08-11 | Novartis Ag | Cna_B domain antigens in vaccines against gram positive bacteria |
| EP2411046B1 (de) | 2009-03-23 | 2017-12-06 | Epitopix, LLC | Polypeptide und immunisierungszusammensetzungen mit gram-prositiven polypeptiden und anwendungsverfahren |
| JP5747370B2 (ja) * | 2009-03-31 | 2015-07-15 | 国立大学法人浜松医科大学 | 高病原性口腔細菌の高感度検出法 |
| PT3281947T (pt) | 2009-04-03 | 2020-05-07 | Univ Chicago | Composições e métodos relacionados com variantes da proteína a (spa) |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2284193A1 (de) * | 2009-08-10 | 2011-02-16 | Kenta Biotech AG | Menschlicher monoklonaler Antikörper gegen S.aureus aus Alpha-Toxin und seine Verwendung bei der Behandlung oder Vorbeugung der Abszessbildung |
| WO2011111790A1 (ja) * | 2010-03-10 | 2011-09-15 | 国立大学法人浜松医科大学 | 高病原性口腔細菌による腸炎誘発原因分子の産生とその高感度検出法 |
| EP2555794A4 (de) | 2010-04-05 | 2014-01-15 | Univ Chicago | Zusammensetzungen und verfahren im zusammenhang mit protein-a-(spa)-antikörpern als immunreaktionsverstärker |
| EP2588120B1 (de) | 2010-07-02 | 2017-11-15 | The University of Chicago | Zusammensetzungen und verfahren bezüglich protein-a (spa)-varianten |
| EP2614074A1 (de) | 2010-09-09 | 2013-07-17 | The University of Chicago | Verfahren und zusammensetzungen mit schützenden staphylokokken-antigenen |
| US8182842B1 (en) | 2010-11-10 | 2012-05-22 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Physico-chemical-managed killing of penicillin-resistant static and growing gram-positive and gram-negative vegetative bacteria |
| US8440618B2 (en) * | 2011-01-19 | 2013-05-14 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Composition for the attachment of implants to collagen or other components of biological tissue |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| AU2012287513A1 (en) | 2011-07-22 | 2014-03-13 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Methods and compositions for vaccinating against Staphylococcus aureus |
| EP2744517B1 (de) | 2011-08-15 | 2019-03-13 | The University of Chicago | Zusammensetzungen und verfahren in zusammenhang mit antikörpern gegen das staphylokokken-protein a |
| HRP20201127T1 (hr) | 2012-04-26 | 2020-11-27 | University Of Chicago | Antigeni stafilokokne koagulaze i metode primjene istih |
| HK1207321A1 (en) | 2012-04-26 | 2016-01-29 | University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
| AU2014227748B2 (en) | 2013-03-15 | 2019-02-14 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
| US11531028B2 (en) | 2013-05-10 | 2022-12-20 | Nordic Bioscience A/S | Collagen type X alpha-1 assay |
| US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
| WO2017087838A2 (en) * | 2015-11-19 | 2017-05-26 | George Mason University | Dual inhibitory action peptidomimetic inhibitor for il-33 and il-1beta |
| JP2019507759A (ja) | 2016-03-09 | 2019-03-22 | ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター | 外陰部膣カンジダ症の予防及び治療で使用するための方法及びキット |
| AU2019366956B2 (en) | 2018-10-23 | 2025-10-30 | Dragonfly Therapeutics, Inc. | Heterodimeric Fc-fused proteins |
| BR112021022902A2 (pt) | 2019-05-14 | 2022-01-25 | Univ Chicago | Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) |
| WO2021051136A1 (en) | 2019-09-13 | 2021-03-18 | The University Of Chicago | Methods and compositions for treating staphylococcal infections |
| IL291821A (en) | 2019-10-02 | 2022-06-01 | Janssen Vaccines & Prevention Bv | Staphylococcus peptides and methods of use |
| WO2021216916A1 (en) | 2020-04-22 | 2021-10-28 | Dragonfly Therapeutics, Inc. | Formulation, dosage regimen, and manufacturing process for heterodimeric fc-fused proteins |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5189015A (en) * | 1984-05-30 | 1993-02-23 | Alfa-Laval Agri International Ab | Method for prophylactic treatment of the colonization of a Staphylococcus aureus bacterial strain by bacterial cell surface protein with fibronectin and fibrinogen binding ability |
| GB8516421D0 (en) | 1985-06-28 | 1985-07-31 | Biotechnology Interface Ltd | Fibronectins |
| US5300434A (en) * | 1987-11-06 | 1994-04-05 | Washington Research Foundation | Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide |
| US5270030A (en) * | 1988-12-29 | 1993-12-14 | Bio-Technology General Corp. | Fibrin binding domain polypeptide and method of producing |
| US5851794A (en) * | 1990-10-22 | 1998-12-22 | Alfa Laval Ab | Collagen binding protein as well as its preparation |
| SE9003374D0 (sv) | 1990-10-22 | 1990-10-22 | Alfa Laval Agri Int | A collagen binding protein as well as its preparation |
| US5980908A (en) * | 1991-12-05 | 1999-11-09 | Alfa Laval Ab | Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment |
| US5491130A (en) | 1992-11-10 | 1996-02-13 | The United States Of America As Represented By The Department Of Health And Human Services | Peptide inhibitors of fibronectin and related collagen-binding proteins |
| US5624904A (en) * | 1993-11-17 | 1997-04-29 | Massachusetts Institute Of Technology | Method for treating gram positive septicemia |
| US6008341A (en) * | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US5858709A (en) * | 1996-10-15 | 1999-01-12 | Smithkline Beecham P.L.C. | Fibronectin binding protein B compounds |
| US6013482A (en) * | 1996-10-15 | 2000-01-11 | Smithkline Beecham Plc | Cell surface protein compounds |
| EP0950068B1 (de) * | 1996-05-16 | 2005-11-09 | THE TEXAS A&M UNIVERSITY SYSTEM | Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen |
| US5789171A (en) * | 1996-06-20 | 1998-08-04 | Board Of Trustees Of The University Of Arkansas | Use of cna, fnba, fnbb, and hlb, gene probes for the strain-specific identification of Staphylococcus aureus |
-
1997
- 1997-05-14 EP EP97926514A patent/EP0950068B1/de not_active Expired - Lifetime
- 1997-05-14 ES ES97926514T patent/ES2252785T3/es not_active Expired - Lifetime
- 1997-05-14 CA CA002255669A patent/CA2255669A1/en not_active Abandoned
- 1997-05-14 DK DK97926514T patent/DK0950068T3/da active
- 1997-05-14 DE DE69734601T patent/DE69734601T2/de not_active Expired - Fee Related
- 1997-05-14 WO PCT/US1997/008210 patent/WO1997043314A2/en not_active Ceased
- 1997-05-14 AT AT97926514T patent/ATE309271T1/de not_active IP Right Cessation
- 1997-05-14 US US08/856,253 patent/US6288214B1/en not_active Expired - Fee Related
- 1997-05-14 AU AU31260/97A patent/AU3126097A/en not_active Abandoned
-
2001
- 2001-03-22 US US09/813,820 patent/US20020102262A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0950068A2 (de) | 1999-10-20 |
| US20020102262A1 (en) | 2002-08-01 |
| EP0950068B1 (de) | 2005-11-09 |
| WO1997043314A2 (en) | 1997-11-20 |
| DK0950068T3 (da) | 2006-02-13 |
| WO1997043314A3 (en) | 1997-12-24 |
| AU3126097A (en) | 1997-12-05 |
| DE69734601T2 (de) | 2006-08-03 |
| DE69734601D1 (de) | 2005-12-15 |
| ES2252785T3 (es) | 2006-05-16 |
| CA2255669A1 (en) | 1997-11-20 |
| US6288214B1 (en) | 2001-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0950068 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |