ATE309271T1 - Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen - Google Patents
Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungenInfo
- Publication number
- ATE309271T1 ATE309271T1 AT97926514T AT97926514T ATE309271T1 AT E309271 T1 ATE309271 T1 AT E309271T1 AT 97926514 T AT97926514 T AT 97926514T AT 97926514 T AT97926514 T AT 97926514T AT E309271 T1 ATE309271 T1 AT E309271T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- binding protein
- prevention
- cna
- dna segments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1767896P | 1996-05-16 | 1996-05-16 | |
| PCT/US1997/008210 WO1997043314A2 (en) | 1996-05-16 | 1997-05-14 | Collagen binding protein compositions and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309271T1 true ATE309271T1 (de) | 2005-11-15 |
Family
ID=21783969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97926514T ATE309271T1 (de) | 1996-05-16 | 1997-05-14 | Zusammensetzungen von kollagenbindungsprotein und verfahren zur deren verwendungen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6288214B1 (de) |
| EP (1) | EP0950068B1 (de) |
| AT (1) | ATE309271T1 (de) |
| AU (1) | AU3126097A (de) |
| CA (1) | CA2255669A1 (de) |
| DE (1) | DE69734601T2 (de) |
| DK (1) | DK0950068T3 (de) |
| ES (1) | ES2252785T3 (de) |
| WO (1) | WO1997043314A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69734601T2 (de) * | 1996-05-16 | 2006-08-03 | The Texas A & M University System, College Station | Zusammensetzung von kollagenbindungsprotein und verfahren zu deren verwendungen |
| US6610293B1 (en) * | 1997-06-16 | 2003-08-26 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria |
| US6692739B1 (en) * | 1998-08-31 | 2004-02-17 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| ES2322409T3 (es) * | 1998-08-31 | 2009-06-19 | Inhibitex, Inc. | Vacunas multicomponentes contra staphylococcus aureus. |
| EP1121149A4 (de) * | 1998-08-31 | 2002-03-20 | Inhibitex Inc | Immunotherapeutika gegen staphylokokkus mittels donor selektion und donor stimulation |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20020092987A1 (en) * | 1998-09-05 | 2002-07-18 | Taehee Cho | Photo detect device using quantum dots and materialization method thereof |
| US6908994B1 (en) | 1999-05-10 | 2005-06-21 | The Texas A&M University System | Collagen-binding proteins from enterococcal bacteria |
| EP1177203B1 (de) * | 1999-05-10 | 2011-10-05 | The Texas A&M University System | Kollagen-bindende proteine von enterococcalen bakterien |
| JP4393739B2 (ja) | 1999-08-02 | 2010-01-06 | ソフトバンクBb株式会社 | 電子決済システム、決済装置及び端末 |
| US20070077256A1 (en) * | 1999-11-19 | 2007-04-05 | Los Angeles Biomedical Research Institute | Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents |
| CA2403359A1 (en) * | 2000-03-17 | 2001-09-27 | Inhibitex, Inc. | Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use |
| GB0014907D0 (en) * | 2000-06-20 | 2000-08-09 | Univ Sheffield | Antigenic polypeptides |
| PT1377314E (pt) | 2001-01-26 | 2012-01-02 | Inhibitex Inc | Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções |
| JP2002253712A (ja) * | 2001-03-02 | 2002-09-10 | Endo Mfg Co Ltd | ゴルフクラブ |
| US6790448B2 (en) * | 2001-05-08 | 2004-09-14 | The Texas A&M University System University | Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them |
| WO2002092117A1 (en) | 2001-05-11 | 2002-11-21 | The Texas A & M University System | Method and compositions for inhibiting thrombin-induced coagulation |
| MXPA03011701A (es) | 2001-06-15 | 2004-12-06 | Nhibitex Inc | Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus. |
| US7115264B2 (en) * | 2001-11-05 | 2006-10-03 | Inhibitex | Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections |
| US20030153026A1 (en) * | 2002-01-04 | 2003-08-14 | Javier Alarcon | Entrapped binding protein as biosensors |
| US6855556B2 (en) | 2002-01-04 | 2005-02-15 | Becton, Dickinson And Company | Binding protein as biosensors |
| JP2006502968A (ja) * | 2002-02-21 | 2006-01-26 | ユニヴエルシタ デリ スツディ ディ パヴィア | 細菌性コラーゲン結合タンパク質に対して交差反応性のモノクロナール抗体 |
| EP1481011A4 (de) * | 2002-03-05 | 2007-05-30 | Inhibitex Inc | Monoklonale und polyklonale antikörper, die koagulasenegative staphylokokkenproteine erkennen |
| CA2517439C (en) | 2003-03-07 | 2013-07-23 | Wyeth Holdings Corporation | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| DE602005022704D1 (de) * | 2004-06-09 | 2010-09-16 | Dickinson And Co | Sensor für mehrere analyte |
| NZ553776A (en) | 2004-09-22 | 2010-05-28 | Glaxosmithkline Biolog Sa | Immunogenic composition comprising staphylococcal PNAG and Type 5 and/or 8 Capsular polysaccharide or oligosaccharide. |
| US8007806B2 (en) * | 2005-01-20 | 2011-08-30 | Isconova Ab | Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide |
| JP4726109B2 (ja) * | 2005-02-10 | 2011-07-20 | 昭和電工株式会社 | 皮膚外用剤、それを用いる皮膚有害微生物の付着予防方法及び増殖防止方法 |
| US8007811B2 (en) * | 2005-02-14 | 2011-08-30 | Epitopix, Llc | Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use |
| WO2006138627A2 (en) * | 2005-06-16 | 2006-12-28 | Inhibitex, Inc. | Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein |
| CA2614927A1 (en) * | 2005-07-25 | 2007-02-01 | Nanotechnology Victoria Pty Ltd | Microarray device |
| WO2007030012A2 (en) * | 2005-09-05 | 2007-03-15 | Stichting Voor De Technische Wetenscahappen | Extracellular matrix imaging |
| EP1996231A4 (de) * | 2006-02-22 | 2010-09-15 | Texas A & M Univ Sys | Antikörper mit stark expressierter putativer antigenerkennung von ca-mrsa und verwendungsverfahren |
| EP2476433A1 (de) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogene Zusammensetzung |
| AU2007240316A1 (en) | 2006-04-20 | 2007-11-01 | Becton, Dickinson And Company | Thermostable proteins and methods of making and using thereof |
| US20180221466A9 (en) * | 2006-06-12 | 2018-08-09 | Glaxosmithkline Biologicals S.A. | Use of alpha-toxin for treating and preventing staphylococcus infections |
| US9181329B2 (en) | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| JP5658564B2 (ja) * | 2007-08-31 | 2015-01-28 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌肺疾患および状態に対する免疫に関連した方法および組成物 |
| WO2010014304A1 (en) * | 2008-07-29 | 2010-02-04 | University Of Chicago | Compositions and methods related to staphylococcal bacterium proteins |
| EP2341929B1 (de) | 2008-10-06 | 2017-01-25 | University Of Chicago | Zusammensetzungen und verfahren im zusammenhang mit bakteriellen emp proteinen |
| CN103897045A (zh) * | 2009-01-12 | 2014-07-02 | 诺华股份有限公司 | 抗革兰氏阳性细菌疫苗中的Cna_B结构域 |
| BRPI1011856A2 (pt) | 2009-03-23 | 2020-11-03 | Epitopix, Llc | polipeptídeos e composições de imunização contendo polipeptídeos gram-positivos e métodos de uso |
| JP5747370B2 (ja) * | 2009-03-31 | 2015-07-15 | 国立大学法人浜松医科大学 | 高病原性口腔細菌の高感度検出法 |
| HUE026855T2 (en) | 2009-04-03 | 2016-07-28 | Univ Chicago | Compositions and methods related to protein a (spa) variants |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2284193A1 (de) * | 2009-08-10 | 2011-02-16 | Kenta Biotech AG | Menschlicher monoklonaler Antikörper gegen S.aureus aus Alpha-Toxin und seine Verwendung bei der Behandlung oder Vorbeugung der Abszessbildung |
| WO2011111790A1 (ja) | 2010-03-10 | 2011-09-15 | 国立大学法人浜松医科大学 | 高病原性口腔細菌による腸炎誘発原因分子の産生とその高感度検出法 |
| EP2555794A4 (de) | 2010-04-05 | 2014-01-15 | Univ Chicago | Zusammensetzungen und verfahren im zusammenhang mit protein-a-(spa)-antikörpern als immunreaktionsverstärker |
| CA2803298C (en) | 2010-07-02 | 2020-07-14 | The University Of Chicago | Compositions and methods related to protein a (spa) variants |
| EP2614074A1 (de) | 2010-09-09 | 2013-07-17 | The University of Chicago | Verfahren und zusammensetzungen mit schützenden staphylokokken-antigenen |
| US8182842B1 (en) | 2010-11-10 | 2012-05-22 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Physico-chemical-managed killing of penicillin-resistant static and growing gram-positive and gram-negative vegetative bacteria |
| US8440618B2 (en) * | 2011-01-19 | 2013-05-14 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Composition for the attachment of implants to collagen or other components of biological tissue |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| GEP201706766B (en) | 2011-07-22 | 2017-10-25 | Los Angeles Biomedical Res Center | Methods and compositions for vaccinating against staphylococcus aureus |
| BR112014003315A2 (pt) | 2011-08-15 | 2017-03-01 | Univ Chicago | composições e métodos relacionados a anticorpos para a proteína a estafilocócica |
| JP6670106B2 (ja) | 2012-04-26 | 2020-03-18 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌コアグラーゼ抗原およびその使用方法 |
| CN104703622B (zh) | 2012-04-26 | 2017-05-24 | 芝加哥大学 | 与金黄色葡萄球菌疾病期间抵消凝固酶活性的抗体相关的组合物和方法 |
| US10130691B2 (en) | 2013-03-15 | 2018-11-20 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for treating fungal and bacterial pathogens |
| US11531028B2 (en) | 2013-05-10 | 2022-12-20 | Nordic Bioscience A/S | Collagen type X alpha-1 assay |
| US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
| WO2017087838A2 (en) * | 2015-11-19 | 2017-05-26 | George Mason University | Dual inhibitory action peptidomimetic inhibitor for il-33 and il-1beta |
| EP3426287A4 (de) | 2016-03-09 | 2020-03-11 | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Verfahren und kits zur verwendung bei der vorbeugung und behandlung von vulvovaginaler candidose |
| SG11202104136YA (en) | 2018-10-23 | 2021-05-28 | Dragonfly Therapeutics Inc | Heterodimeric fc-fused proteins |
| US12514914B2 (en) | 2019-05-14 | 2026-01-06 | The University Of Chicago | Methods and compositions comprising Staphylococcus protein a (SpA) variants |
| CN114929750B (zh) | 2019-09-13 | 2024-11-22 | 芝加哥大学 | 用于治疗葡萄球菌感染的方法和组合物 |
| JP2022550884A (ja) | 2019-10-02 | 2022-12-05 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | スタフィロコッカス(Staphylococcus)ペプチドおよび使用方法 |
| MX2022013112A (es) | 2020-04-22 | 2023-01-16 | Dragonfly Therapeutics Inc | Fórmulacion, regimen de dosificación y proceso de manufactura de proteínas heterodiméricas fusionadas con fc. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5189015A (en) * | 1984-05-30 | 1993-02-23 | Alfa-Laval Agri International Ab | Method for prophylactic treatment of the colonization of a Staphylococcus aureus bacterial strain by bacterial cell surface protein with fibronectin and fibrinogen binding ability |
| GB8516421D0 (en) | 1985-06-28 | 1985-07-31 | Biotechnology Interface Ltd | Fibronectins |
| US5300434A (en) * | 1987-11-06 | 1994-04-05 | Washington Research Foundation | Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide |
| US5270030A (en) * | 1988-12-29 | 1993-12-14 | Bio-Technology General Corp. | Fibrin binding domain polypeptide and method of producing |
| US5851794A (en) * | 1990-10-22 | 1998-12-22 | Alfa Laval Ab | Collagen binding protein as well as its preparation |
| SE9003374D0 (sv) * | 1990-10-22 | 1990-10-22 | Alfa Laval Agri Int | A collagen binding protein as well as its preparation |
| US5980908A (en) * | 1991-12-05 | 1999-11-09 | Alfa Laval Ab | Bacterial cell surface protein with fibronectin, fibrinogen, collagen and laminin binding ability, process for the manufacture of the protein and prophylactic treatment |
| US5491130A (en) | 1992-11-10 | 1996-02-13 | The United States Of America As Represented By The Department Of Health And Human Services | Peptide inhibitors of fibronectin and related collagen-binding proteins |
| US5624904A (en) * | 1993-11-17 | 1997-04-29 | Massachusetts Institute Of Technology | Method for treating gram positive septicemia |
| US6008341A (en) * | 1994-08-22 | 1999-12-28 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | S. aureus fibrinogen binding protein gene |
| US5858709A (en) * | 1996-10-15 | 1999-01-12 | Smithkline Beecham P.L.C. | Fibronectin binding protein B compounds |
| US6013482A (en) * | 1996-10-15 | 2000-01-11 | Smithkline Beecham Plc | Cell surface protein compounds |
| DE69734601T2 (de) * | 1996-05-16 | 2006-08-03 | The Texas A & M University System, College Station | Zusammensetzung von kollagenbindungsprotein und verfahren zu deren verwendungen |
| US5789171A (en) * | 1996-06-20 | 1998-08-04 | Board Of Trustees Of The University Of Arkansas | Use of cna, fnba, fnbb, and hlb, gene probes for the strain-specific identification of Staphylococcus aureus |
-
1997
- 1997-05-14 DE DE69734601T patent/DE69734601T2/de not_active Expired - Fee Related
- 1997-05-14 AT AT97926514T patent/ATE309271T1/de not_active IP Right Cessation
- 1997-05-14 DK DK97926514T patent/DK0950068T3/da active
- 1997-05-14 AU AU31260/97A patent/AU3126097A/en not_active Abandoned
- 1997-05-14 ES ES97926514T patent/ES2252785T3/es not_active Expired - Lifetime
- 1997-05-14 EP EP97926514A patent/EP0950068B1/de not_active Expired - Lifetime
- 1997-05-14 CA CA002255669A patent/CA2255669A1/en not_active Abandoned
- 1997-05-14 US US08/856,253 patent/US6288214B1/en not_active Expired - Fee Related
- 1997-05-14 WO PCT/US1997/008210 patent/WO1997043314A2/en not_active Ceased
-
2001
- 2001-03-22 US US09/813,820 patent/US20020102262A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69734601T2 (de) | 2006-08-03 |
| EP0950068A2 (de) | 1999-10-20 |
| US20020102262A1 (en) | 2002-08-01 |
| EP0950068B1 (de) | 2005-11-09 |
| US6288214B1 (en) | 2001-09-11 |
| AU3126097A (en) | 1997-12-05 |
| DE69734601D1 (de) | 2005-12-15 |
| WO1997043314A3 (en) | 1997-12-24 |
| WO1997043314A2 (en) | 1997-11-20 |
| ES2252785T3 (es) | 2006-05-16 |
| CA2255669A1 (en) | 1997-11-20 |
| DK0950068T3 (da) | 2006-02-13 |
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