ATE461709T1 - Choline-bindende proteine derivate aus pneumokoken als impfstoff - Google Patents

Choline-bindende proteine derivate aus pneumokoken als impfstoff

Info

Publication number
ATE461709T1
ATE461709T1 AT99915326T AT99915326T ATE461709T1 AT E461709 T1 ATE461709 T1 AT E461709T1 AT 99915326 T AT99915326 T AT 99915326T AT 99915326 T AT99915326 T AT 99915326T AT E461709 T1 ATE461709 T1 AT E461709T1
Authority
AT
Austria
Prior art keywords
choline
pneumococes
vaccines
binding proteins
provides
Prior art date
Application number
AT99915326T
Other languages
English (en)
Inventor
Theresa Wizemann
Scott Koenig
Leslie Johnson
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Application granted granted Critical
Publication of ATE461709T1 publication Critical patent/ATE461709T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
AT99915326T 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff ATE461709T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US8574398P 1998-05-15 1998-05-15
PCT/US1999/007680 WO1999051266A2 (en) 1998-04-07 1999-04-06 Derivatives of pneumococcal choline binding proteins for vaccines

Publications (1)

Publication Number Publication Date
ATE461709T1 true ATE461709T1 (de) 2010-04-15

Family

ID=26764078

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99915326T ATE461709T1 (de) 1998-04-07 1999-04-06 Choline-bindende proteine derivate aus pneumokoken als impfstoff

Country Status (16)

Country Link
US (3) US6503511B1 (de)
EP (1) EP1067962B1 (de)
JP (1) JP2002510649A (de)
KR (2) KR20060126844A (de)
CN (1) CN1200731C (de)
AT (1) ATE461709T1 (de)
AU (1) AU766455C (de)
BR (1) BR9909483A (de)
CA (1) CA2325340A1 (de)
DE (1) DE69942176D1 (de)
ES (1) ES2343492T3 (de)
HU (1) HUP0102617A3 (de)
IL (2) IL138798A0 (de)
NO (1) NO20004972L (de)
NZ (2) NZ530277A (de)
WO (1) WO1999051266A2 (de)

Families Citing this family (38)

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US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CA2326388C (en) * 1998-04-07 2014-02-04 St. Jude Children's Research Hospital A polypeptide comprising the amino acid of an n-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
EP1067962B1 (de) * 1998-04-07 2010-03-24 MedImmune, LLC Choline-bindende proteine derivate aus pneumokoken als impfstoff
US20010016200A1 (en) 1998-04-23 2001-08-23 Briles David E. Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
JP2002539273A (ja) 1999-03-19 2002-11-19 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム ワクチン
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
WO2002008426A2 (en) * 2000-07-20 2002-01-31 Hansa Medical Ab Fh-binding protein of streptococcus pneumoniae
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
US6674504B1 (en) 2000-09-29 2004-01-06 Kent Optronics, Inc. Single layer multi-state ultra-fast cholesteric liquid crystal device and the fabrication methods thereof
CA2493124C (en) 2002-08-02 2014-04-29 Glaxosmithkline Biologicals S.A. Vaccine
MXPA05004528A (es) 2002-11-01 2005-07-26 Glaxosmithkline Biolog Sa Composicion inmunogenica.
ATE474595T1 (de) 2003-10-02 2010-08-15 Glaxosmithkline Biolog Sa B. pertussis antigene und ihre verwendung bei der vakzinierung
GB0505996D0 (en) 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
US8052971B2 (en) * 2005-11-21 2011-11-08 MG Biologics Oral use of specific antibodies for intestinal health
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
BRPI0620460B8 (pt) 2005-12-22 2021-05-25 Glaxosmithkline Biologicals Sa uso de composição imunogênica para bebês, e, processo para produzir uma vacina
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
EP1973933B1 (de) 2006-01-17 2020-06-24 Forsgren, Arne Neues oberflächenexponiertes haemophilus influenzae-protein (protein e; pe)
US8722055B2 (en) 2006-09-27 2014-05-13 St. Jude Children's Research Hospital Synthetic Streptococcus pneumoniae vaccine
BRPI0813644B8 (pt) 2007-06-26 2021-05-25 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, processo para fabricar a mesma, e, uso da composição imunogênica ou vacina
JP5056490B2 (ja) * 2008-03-10 2012-10-24 富士通株式会社 歪み補償係数更新装置および歪み補償増幅器
US20120164178A1 (en) 2008-04-16 2012-06-28 Ballou Jr William Ripley Vaccine
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
EP2544714A1 (de) 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Impfstoffzusammensetzung
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
CA2832115C (en) 2011-04-08 2021-03-02 Tufts Medical Center, Inc. Pepducin design and use
SG194733A1 (en) 2011-05-17 2013-12-30 Glaxosmithkline Biolog Sa Vaccine against streptococcus pneumoniae
JP2014000016A (ja) * 2012-06-15 2014-01-09 National Agriculture & Food Research Organization 豚丹毒菌の新規な抗原タンパク質、その遺伝子、及び組換えベクターとその利用
GB201318170D0 (en) * 2013-10-14 2013-11-27 Univ Edinburgh Proteins with Diagnostic and Therapeutic Uses
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
JP7621728B2 (ja) 2015-11-13 2025-01-27 オアシス ファーマシューティカルズ， エルエルシー プロテアーゼ活性化受容体２のモジュレーター
KR20240018698A (ko) 2017-06-10 2024-02-13 인벤트프라이즈 인크. 면역원성과 항원항체 결합성이 개선된 2가 또는 다가 접합체 다당류를 가진 다가 접합체 백신
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
EP4192499A4 (de) 2020-08-10 2024-09-25 Inventprise, Inc. Multivalente pneumokokken-glykokonjugat-impfstoffe, die nachkommende serotyp 24f enthalten

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US6231870B1 (en) * 1995-06-02 2001-05-15 Uab Research Foundation Oral administration of pneumoccal antigens
US6042838A (en) * 1991-02-15 2000-03-28 Uab Research Foundation immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA)
US6232116B1 (en) * 1991-02-15 2001-05-15 University Of Alabama At Birmingham Research Foundation Oral administration of pneumococcal antigens
US6027734A (en) * 1991-02-15 2000-02-22 Uab Research Foundation Mucosal administration of pneumococcal antigens
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US7078042B2 (en) * 1995-09-15 2006-07-18 Uab Research Foundation Pneumococcal surface protein C (PspC), epitopic regions and strain selection thereof, and uses therefor
US6245335B1 (en) * 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
EP0912608B1 (de) * 1996-05-01 2006-04-19 The Rockefeller University Cholin-bindendes Protein, welches als gegen Pneumokokken gerichtetes Vakzin verwendet wird
CA2271720A1 (en) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
NZ335864A (en) * 1996-11-06 2001-09-28 Univ California Isolated tumor necrosis factor receptor releasing enzyme (TRRE), compositions comprising the enzyme and methods of the use in modulation of TNF levels
CA2269636A1 (en) * 1996-11-12 1998-05-22 The Regents Of The University Of Minnesota C3 binding protein of streptococcus pneumoniae
DE19708537A1 (de) 1997-03-03 1998-09-10 Biotechnolog Forschung Gmbh Neues Oberflächenprotein (SpsA-Protein) von Streptococcus pneumoniae etc.
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
EP1067962B1 (de) * 1998-04-07 2010-03-24 MedImmune, LLC Choline-bindende proteine derivate aus pneumokoken als impfstoff
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US6936252B2 (en) * 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
DE69940439D1 (de) * 1998-12-21 2009-04-02 Medimmune Inc Streptococcus pneumoniae proteine und immunogene fragmente für impstoffe
US6689369B2 (en) * 2000-04-27 2004-02-10 Medimmune, Inc. Immunogenic pneumococcal protein and vaccine compositions thereof
EP2921924B1 (de) * 2014-03-21 2018-09-19 Asco Numatics GmbH Vorrichtung zur Bereitstellung eines Fluids mit geregeltem Ausgangsdruck
US9741151B2 (en) * 2015-04-14 2017-08-22 International Business Machines Corporation Mobile interactive comparison chart

Also Published As

Publication number Publication date
AU766455C (en) 2004-12-02
US7435421B2 (en) 2008-10-14
US6503511B1 (en) 2003-01-07
EP1067962B1 (de) 2010-03-24
JP2002510649A (ja) 2002-04-09
NO20004972D0 (no) 2000-10-03
KR20060126844A (ko) 2006-12-08
IL138798A (en) 2008-11-03
CA2325340A1 (en) 1999-10-14
BR9909483A (pt) 2001-10-09
US20050142145A1 (en) 2005-06-30
US20030138447A1 (en) 2003-07-24
AU766455B2 (en) 2003-10-16
DE69942176D1 (de) 2010-05-06
NZ530277A (en) 2005-08-26
WO1999051266A2 (en) 1999-10-14
KR20010034752A (ko) 2001-04-25
AU3386999A (en) 1999-10-25
KR100794394B1 (ko) 2008-01-15
EP1067962A2 (de) 2001-01-17
NO20004972L (no) 2000-12-05
HUP0102617A3 (en) 2006-04-28
CN1315870A (zh) 2001-10-03
CN1200731C (zh) 2005-05-11
WO1999051266A3 (en) 1999-12-09
IL138798A0 (en) 2001-10-31
HUP0102617A2 (hu) 2001-11-28
NZ507717A (en) 2004-02-27
US6863893B2 (en) 2005-03-08
ES2343492T3 (es) 2010-08-02

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