ATE309375T1 - Onkostatin- m rezeptor - Google Patents

Onkostatin- m rezeptor

Info

Publication number
ATE309375T1
ATE309375T1 AT95920626T AT95920626T ATE309375T1 AT E309375 T1 ATE309375 T1 AT E309375T1 AT 95920626 T AT95920626 T AT 95920626T AT 95920626 T AT95920626 T AT 95920626T AT E309375 T1 ATE309375 T1 AT E309375T1
Authority
AT
Austria
Prior art keywords
oncostatin
receptor
rbeta
osm
onkostatin
Prior art date
Application number
AT95920626T
Other languages
English (en)
Inventor
Bruce Mosley
David J Cosman
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE309375T1 publication Critical patent/ATE309375T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AT95920626T 1994-05-26 1995-05-22 Onkostatin- m rezeptor ATE309375T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24955394A 1994-05-26 1994-05-26
US08/308,881 US5783672A (en) 1994-05-26 1994-09-12 Receptor for oncostatin M
PCT/US1995/006530 WO1995033059A2 (en) 1994-05-26 1995-05-22 Receptor for oncostatin m

Publications (1)

Publication Number Publication Date
ATE309375T1 true ATE309375T1 (de) 2005-11-15

Family

ID=26940161

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95920626T ATE309375T1 (de) 1994-05-26 1995-05-22 Onkostatin- m rezeptor

Country Status (10)

Country Link
US (7) US5783672A (de)
EP (1) EP0760857B9 (de)
JP (1) JP4392058B2 (de)
AT (1) ATE309375T1 (de)
AU (1) AU694232B2 (de)
CA (1) CA2190371C (de)
DE (1) DE69534593T2 (de)
DK (1) DK0760857T5 (de)
ES (1) ES2249770T3 (de)
WO (1) WO1995033059A2 (de)

Families Citing this family (46)

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US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
GB9419021D0 (en) 1994-09-21 1994-11-09 Applied Research Systems Therapeutic protein
KR19990022359A (ko) * 1995-06-07 1999-03-25 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 시토킨 시그날 트랜스듀서 ｇｐ130 ｍＲＮＡ에 특이적인 올리고뉴클레오티드
US5747470A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Method for inhibiting cellular proliferation using antisense oligonucleotides to gp130 mRNA
US5674995A (en) * 1995-06-07 1997-10-07 Gen-Probe Incorporated Oligonucleotides specific for cytokine signal transducer gp130 mRNA
EP0869176A4 (de) * 1995-11-07 2000-09-20 Kaneka Corp Autoantigene
JP2001505053A (ja) * 1996-11-20 2001-04-17 ジェネティックス・インスチチュート・インコーポレーテッド 分泌蛋白およびそれらをコードするポリヌクレオチド
US6455040B1 (en) * 1997-01-14 2002-09-24 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
EP0990031B1 (de) * 1997-01-14 2006-03-29 Human Genome Sciences, Inc. Tumor-nekrose-faktor rezeptor 5
US6271343B1 (en) * 1997-05-01 2001-08-07 Zymogenetics, Inc. Mammalian cytokine-like receptor 5
GB9806530D0 (en) 1998-03-26 1998-05-27 Glaxo Group Ltd Inflammatory mediator
ATE332373T1 (de) * 1998-08-21 2006-07-15 Immunex Corp Menschlisches il-1 epsilon dna und polypeptide
US6803451B2 (en) 1998-09-23 2004-10-12 Zymogenetics, Inc. Cytokine receptor zalpha11 polypeptides
US6576744B1 (en) 1998-09-23 2003-06-10 Zymogenetics, Inc. Cytokine receptor zalpha11
DK1188830T3 (da) 1999-06-02 2010-04-26 Chugai Pharmaceutical Co Ltd Nyt hæmopoietinreceptorprotein NR10
EP1221482B1 (de) 1999-09-27 2005-12-28 Chugai Seiyaku Kabushiki Kaisha HäMOPOIETINREZEPTOR-PROTEIN, NR12
ES2279809T3 (es) 2000-04-05 2007-09-01 Zymogenetics, Inc. Receptores de citoquina zalfa11 solubles.
DE60037648T2 (de) * 2000-04-21 2010-06-17 Conaris Research Institute Ag Fusionsproteine, die zwei lösliche gp130 Moleküle enthalten
WO2004003140A2 (en) 2002-01-18 2004-01-08 Zymogenetics, Inc. Cytokine receptor zcytor17 multimers
US9738700B2 (en) 2002-01-18 2017-08-22 Zymogenetics Inc. ZCYTOR17 heterodimeric cytokine receptor
RU2490276C2 (ru) 2002-01-18 2013-08-20 Займоджинетикс, Инк. Новый лиганд рецептора цитокина zcytor17
US7261861B2 (en) 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
EP1491554A1 (de) * 2003-06-23 2004-12-29 CONARIS research institute AG PEGlierte lösliche gp130-Dimeren geignet als Medikament
KR101295139B1 (ko) * 2004-06-07 2013-08-12 레이븐 바이오테크놀로지스, 인코퍼레이티드 트랜스페린 리셉터 항체
ES2309427T3 (es) * 2004-08-27 2008-12-16 Conaris Research Institute Ag Secuencias de nucleotidos optimizidas que codifican para sgp130.
CA2597171A1 (en) * 2005-02-03 2006-08-10 Raven Biotechnologies, Inc. Antibodies to oncostatin m receptor
WO2006113671A2 (en) * 2005-04-15 2006-10-26 Oncomethylome Sciences, S.A. Methylation markers for diagnosis and treatment of cancers
US20130216542A1 (en) 2005-05-06 2013-08-22 Zymogenetics, Inc. Variable region sequences of il-31 monoclonal antibodies and methods of use
US8101183B2 (en) 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
CN101198624B (zh) 2005-05-06 2012-10-10 津莫吉尼蒂克斯公司 Il-31单克隆抗体及使用方法
EP2001906A2 (de) 2006-01-10 2008-12-17 Zymogenetics, Inc. Verfahren zur behandlung von schmerzen und entzündungen in einem nervengewebe mithilfe von il-31ra- und osmrb-antagonisten
ES2544888T3 (es) 2006-06-08 2015-09-04 Chugai Seiyaku Kabushiki Kaisha Prevención o remedio para enfermedades inflamatorias
US7932055B2 (en) 2006-06-22 2011-04-26 Novo Nordisk A/S Soluble heterodimeric CD94/NKG2 receptors fusion proteins
DE602006016765D1 (de) * 2006-06-30 2010-10-21 Conaris Res Inst Ag Verbesserte sgp 130Fc Dimere
CA2708065C (en) 2007-12-05 2015-02-24 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for pruritus
SI2796466T1 (en) 2007-12-07 2018-01-31 Zymogenetics, Inc. Molecules of Humanized Specifics Specifiable for IL-31
US8309688B2 (en) * 2008-12-30 2012-11-13 Centocor Ortho Biotech Inc. Monkey homolog of human oncostatin M and methods of use thereof
MX351887B (es) * 2010-11-23 2017-11-01 Glaxo Group Ltd Proteinas de union a antigeno para oncostatina m (osm).
US9475876B2 (en) 2012-05-11 2016-10-25 Wakayama Medical University Anti oncostatin M receptor beta antibody used for treating atopic dermatitis
HUE056580T2 (hu) 2013-05-30 2022-02-28 Kiniksa Pharmaceuticals Ltd Onkosztatin-M-receptor antigénjét kötõ fehérjék
US9550828B2 (en) 2013-09-05 2017-01-24 Boise State University Oncostatin M (OSM) antagonists for preventing cancer metastasis and IL-6 related disorders
EP3197480A1 (de) 2014-09-24 2017-08-02 Universita' Degli Studi Di Padova Zusammensetzung zur induzierung der mobilisierung von knochenmarkstammzellen
KR20240131465A (ko) 2014-12-01 2024-08-30 훼링 비.브이. 선택적 il-6-트랜스-신호전달 억제제 조성물
EP3226888B1 (de) 2014-12-01 2021-04-21 Ferring B.V. Verabreichung eines selektiven il-6-transsignalisierenden inhibitors
US11633457B2 (en) 2019-04-11 2023-04-25 Boise State University Pharmaceutical compositions comprising oncostatin m (OSM) antagonist derivatives and methods of use
TW202607038A (zh) 2020-10-19 2026-02-16 美商碩騰服務公司 犬及貓抑瘤素Ｍ受體β之抗體及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120535A (en) * 1986-11-26 1992-06-09 Oncogen Oncostatin M and novel compositions having anti-neoplastic activity
JPS6463395A (en) * 1987-05-04 1989-03-09 Oncogen Oncostatin m and novel composition having antitumor activity
US5106731A (en) * 1988-10-21 1992-04-21 The United States Of America As Represented By The Department Of Health And Human Services Kaposi's sarcoma endothelial cells and growth factor
CA2028825A1 (en) * 1989-04-10 1990-10-11 Thomas J. Brown Methods for controlling human endothelial cell proliferation and effector functions using oncostatin m
JP2898064B2 (ja) * 1989-08-03 1999-05-31 忠三 岸本 ヒトｇｐ１３０蛋白質
US5073627A (en) * 1989-08-22 1991-12-17 Immunex Corporation Fusion proteins comprising GM-CSF and IL-3
DE69032471T2 (de) * 1989-12-08 1999-03-04 Bristol-Myers Squibb Company, New York, N.Y. Proteine mit onkostatin-m-aktivität und verfahren zu ihrer herstellung
IL97622A (en) * 1990-03-29 1997-06-10 Oncogen Limited Partnership Se Monoclonal antibodies that inhibit growth of kaposi's sarcoma
CA2097291A1 (en) * 1990-12-13 1992-06-14 David P. Gearing Leukemia inhibitory factor receptors
US5470824A (en) * 1991-05-31 1995-11-28 The Regents Of The University Of California Method to treat Kaposi's sarcoma
KR930703715A (ko) * 1991-11-12 1993-11-30 다쯔타 도키오 접어진 스트립 선로형 유전체 공진기 및 그것을 사용한 적층형 유전체 필터
US5262522A (en) * 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
US5284744A (en) * 1992-08-27 1994-02-08 Eastman Kodak Company Non-ultraviolet-absorbing peptizer for silver halide emulsions
US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M

Also Published As

Publication number Publication date
CA2190371C (en) 2010-08-31
ES2249770T3 (es) 2006-04-01
US5783672A (en) 1998-07-21
US20030109003A1 (en) 2003-06-12
DK0760857T5 (da) 2006-10-30
JP4392058B2 (ja) 2009-12-24
US6010886A (en) 2000-01-04
EP0760857A1 (de) 1997-03-12
US5925740A (en) 1999-07-20
DE69534593D1 (de) 2005-12-15
WO1995033059A2 (en) 1995-12-07
CA2190371A1 (en) 1995-12-07
DE69534593T2 (de) 2006-08-10
WO1995033059A3 (en) 1996-01-04
EP0760857B9 (de) 2006-09-06
US20050260197A1 (en) 2005-11-24
EP0760857B1 (de) 2005-11-09
JPH10501131A (ja) 1998-02-03
US6524817B1 (en) 2003-02-25
AU694232B2 (en) 1998-07-16
DK0760857T3 (da) 2006-01-30
AU2601695A (en) 1995-12-21
US5891997A (en) 1999-04-06

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