ATE310104T1 - Hiv1-vpr-wechselwirkungen mit dem mitochondrialen apoptosis-induzierenden faktor sowie verfahren zur verwendung davon - Google Patents

Hiv1-vpr-wechselwirkungen mit dem mitochondrialen apoptosis-induzierenden faktor sowie verfahren zur verwendung davon

Info

Publication number
ATE310104T1
ATE310104T1 AT02737214T AT02737214T ATE310104T1 AT E310104 T1 ATE310104 T1 AT E310104T1 AT 02737214 T AT02737214 T AT 02737214T AT 02737214 T AT02737214 T AT 02737214T AT E310104 T1 ATE310104 T1 AT E310104T1
Authority
AT
Austria
Prior art keywords
vpr
hiv1
interactions
methods
inducing factor
Prior art date
Application number
AT02737214T
Other languages
English (en)
Inventor
David B Weiner
Karuppiah Muthumani
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of ATE310104T1 publication Critical patent/ATE310104T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G01N2333/163—Regulatory proteins, e.g. tat, nef, rev, vif, vpu, vpr, vpt, vpx
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02737214T 2001-05-25 2002-05-28 Hiv1-vpr-wechselwirkungen mit dem mitochondrialen apoptosis-induzierenden faktor sowie verfahren zur verwendung davon ATE310104T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29357001P 2001-05-25 2001-05-25
PCT/US2002/016731 WO2003040415A1 (en) 2001-05-25 2002-05-28 Hiv-1 vpr interactions with mitochondrial apoptosis inducing factor and methods of using the same

Publications (1)

Publication Number Publication Date
ATE310104T1 true ATE310104T1 (de) 2005-12-15

Family

ID=23129615

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02737214T ATE310104T1 (de) 2001-05-25 2002-05-28 Hiv1-vpr-wechselwirkungen mit dem mitochondrialen apoptosis-induzierenden faktor sowie verfahren zur verwendung davon

Country Status (10)

Country Link
US (1) US7598041B2 (de)
EP (1) EP1397520B1 (de)
JP (1) JP2005508506A (de)
AT (1) ATE310104T1 (de)
AU (1) AU2002310158B2 (de)
CA (1) CA2448162A1 (de)
DE (1) DE60207409T2 (de)
DK (1) DK1397520T3 (de)
ES (1) ES2251596T3 (de)
WO (1) WO2003040415A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL108707A (en) 1993-02-19 1999-06-20 Weiner David B Pharmaceutical compositions and diagnostic kits containing RPH protein or RPV-binding proteins
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5976786A (en) * 1995-12-29 1999-11-02 National Jewish Medical And Research Center Screening methods for the identification of compounds that modulate apoptosis in immunodeficiency virus infected cells
US6060587A (en) * 1996-01-29 2000-05-09 The Trustees Of The University Of Pennsylvania Cellular receptor for HIV-1 VPR essential for G2/M phase transition of the cell cycle
WO1998035234A1 (en) 1997-02-11 1998-08-13 The Regents Of The University Of California Identifying agents for treating lentiviral infection

Also Published As

Publication number Publication date
EP1397520B1 (de) 2005-11-16
EP1397520A4 (de) 2004-07-28
JP2005508506A (ja) 2005-03-31
CA2448162A1 (en) 2003-05-15
WO2003040415A1 (en) 2003-05-15
DE60207409D1 (de) 2005-12-22
DE60207409T2 (de) 2006-07-20
ES2251596T3 (es) 2006-05-01
US20050026138A1 (en) 2005-02-03
DK1397520T3 (da) 2006-03-27
US7598041B2 (en) 2009-10-06
AU2002310158B2 (en) 2007-06-28
EP1397520A1 (de) 2004-03-17

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Legal Events

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