ATE447610T1 - Kristalliner vap-1 und verwendung - Google Patents
Kristalliner vap-1 und verwendungInfo
- Publication number
- ATE447610T1 ATE447610T1 AT04734701T AT04734701T ATE447610T1 AT E447610 T1 ATE447610 T1 AT E447610T1 AT 04734701 T AT04734701 T AT 04734701T AT 04734701 T AT04734701 T AT 04734701T AT E447610 T1 ATE447610 T1 AT E447610T1
- Authority
- AT
- Austria
- Prior art keywords
- vap
- crystalline
- usage
- present
- crystalline vap
- Prior art date
Links
- 101710132836 Membrane primary amine oxidase Proteins 0.000 title abstract 3
- 102000056133 human AOC3 Human genes 0.000 title abstract 2
- 102100027159 Membrane primary amine oxidase Human genes 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 101000694615 Homo sapiens Membrane primary amine oxidase Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030786A FI20030786A0 (fi) | 2003-05-26 | 2003-05-26 | VAP-1:n uusi käyttö |
| FI20040271A FI20040271A0 (fi) | 2004-02-20 | 2004-02-20 | Kiteinen VAP-1 ja sen käyttö |
| PCT/FI2004/000318 WO2004104191A1 (en) | 2003-05-26 | 2004-05-25 | Crystalline vap-1 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE447610T1 true ATE447610T1 (de) | 2009-11-15 |
Family
ID=33477699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04734701T ATE447610T1 (de) | 2003-05-26 | 2004-05-25 | Kristalliner vap-1 und verwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7499847B2 (de) |
| EP (1) | EP1633861B1 (de) |
| JP (1) | JP2007509605A (de) |
| AT (1) | ATE447610T1 (de) |
| AU (1) | AU2004241060B2 (de) |
| CA (1) | CA2526675A1 (de) |
| DE (1) | DE602004023939D1 (de) |
| DK (1) | DK1633861T3 (de) |
| ES (1) | ES2335769T3 (de) |
| NZ (1) | NZ543430A (de) |
| WO (1) | WO2004104191A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20040270A0 (fi) * | 2004-02-20 | 2004-02-20 | Biotie Therapies Oyj | Kuparia sisältävien amiinioksidaasien imhibiittoreina käyttökelpoiset hydratsinoalkoholijohdannaiset |
| CN101680850A (zh) * | 2007-01-12 | 2010-03-24 | 维罗妮卡·詹姆士 | 计量生物学诊断方法 |
| JP2011504485A (ja) * | 2007-11-21 | 2011-02-10 | ファーマクシス リミテッド | Ssao/vap−1のハロアリルアミン阻害剤およびその用途 |
| AU2014279863A1 (en) | 2013-06-12 | 2016-01-28 | Proximagen Limited | New therapeutic uses of enzyme inhibitors |
| WO2015189534A1 (en) | 2014-06-12 | 2015-12-17 | Proximagen Limited | Vap-1 inhibitors for treating muscular dystrophy |
| AU2016366635A1 (en) | 2015-12-07 | 2018-06-21 | Benevolentai Cambridge Limited | VAP-1 inhibitors for treating pain |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5580780A (en) | 1992-06-09 | 1996-12-03 | Jalkanen; Sirpa | Vascular adhesion protein-(VAP-1) and VAP-1-specific antibodies |
| JP2001507238A (ja) * | 1997-05-23 | 2001-06-05 | バイオティ セラピーズ リミティド | アミンオキシダーゼ活性を有する血管付着タンパク質−1 |
| NZ505914A (en) * | 1998-02-06 | 2004-03-26 | Ilexus Pty Ltd | Three-dimensional structures and models of fc receptors and uses thereof |
| EP1313718A2 (de) * | 2000-07-05 | 2003-05-28 | Biotie Therapies Corp. | Inhibitoren kupferhaltiger aminoxidasen |
| US7167801B2 (en) * | 2001-07-12 | 2007-01-23 | Boehringer Ingelheim (Canada) Ltd. | Method of identifying potential inhibitors of human papillomavirus protein E2 using x-ray atomic coordinates |
| US6982286B2 (en) | 2001-07-12 | 2006-01-03 | Biotie Therapies Corp. | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases |
| FI20040270A0 (fi) * | 2004-02-20 | 2004-02-20 | Biotie Therapies Oyj | Kuparia sisältävien amiinioksidaasien imhibiittoreina käyttökelpoiset hydratsinoalkoholijohdannaiset |
-
2004
- 2004-05-25 CA CA002526675A patent/CA2526675A1/en not_active Abandoned
- 2004-05-25 DK DK04734701.8T patent/DK1633861T3/da active
- 2004-05-25 DE DE602004023939T patent/DE602004023939D1/de not_active Expired - Lifetime
- 2004-05-25 EP EP04734701A patent/EP1633861B1/de not_active Expired - Lifetime
- 2004-05-25 JP JP2006530308A patent/JP2007509605A/ja active Pending
- 2004-05-25 WO PCT/FI2004/000318 patent/WO2004104191A1/en not_active Ceased
- 2004-05-25 US US10/557,188 patent/US7499847B2/en not_active Expired - Fee Related
- 2004-05-25 AU AU2004241060A patent/AU2004241060B2/en not_active Ceased
- 2004-05-25 ES ES04734701T patent/ES2335769T3/es not_active Expired - Lifetime
- 2004-05-25 NZ NZ543430A patent/NZ543430A/en not_active IP Right Cessation
- 2004-05-25 AT AT04734701T patent/ATE447610T1/de not_active IP Right Cessation
-
2009
- 2009-01-08 US US12/350,844 patent/US20110021760A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ543430A (en) | 2008-06-30 |
| EP1633861B1 (de) | 2009-11-04 |
| CA2526675A1 (en) | 2004-12-02 |
| US7499847B2 (en) | 2009-03-03 |
| JP2007509605A (ja) | 2007-04-19 |
| US20110021760A1 (en) | 2011-01-27 |
| WO2004104191A1 (en) | 2004-12-02 |
| AU2004241060A1 (en) | 2004-12-02 |
| AU2004241060B2 (en) | 2009-07-23 |
| DK1633861T3 (da) | 2010-03-22 |
| ES2335769T3 (es) | 2010-04-05 |
| DE602004023939D1 (de) | 2009-12-17 |
| HK1086591A1 (en) | 2006-09-22 |
| EP1633861A1 (de) | 2006-03-15 |
| WO2004104191A8 (en) | 2006-08-17 |
| US20070093646A1 (en) | 2007-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1633861 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |