ATE311378T1 - Benzopyran derivate - Google Patents

Benzopyran derivate

Info

Publication number: ATE311378T1
Authority: AT; Austria
Prior art keywords: group; hydrogen atom; alkyl group; substituted; absent
Prior art date: 1999-09-17

Application number

AT00961032T

Other languages

English (en)

Inventor

Keizo Tanikawa

Kazuhiko Ohrai

Kazufumi Yanagihara

Yukihiro Shigeta

Toru Tsukagoshi

Toru Yamashita

Original Assignee

Nissan Chemical Ind Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-09-17

Filing date

2000-09-14

Publication date

2005-12-15

2000-09-14 Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE311378T1 publication Critical patent/ATE311378T1/de

Links

150000001562 benzopyrans Chemical class 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
150000003839 salts Chemical class 0.000 abstract 2
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
-1 (substituted)phenyl group Chemical group 0.000 abstract 1
KYNSBQPICQTCGU-UHFFFAOYSA-N Benzopyrane Chemical compound C1=CC=C2C=CCOC2=C1 KYNSBQPICQTCGU-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
239000003416 antiarrhythmic agent Substances 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000036747 functional refractory period Effects 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)

AT00961032T 1999-09-17 2000-09-14 Benzopyran derivate ATE311378T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP26445599		1999-09-17
PCT/JP2000/006323 WO2001021610A1 (en)	1999-09-17	2000-09-14	Benzopyran derivative

Publications (1)

Publication Number	Publication Date
ATE311378T1 true ATE311378T1 (de)	2005-12-15

Family

ID=17403453

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00961032T ATE311378T1 (de)	1999-09-17	2000-09-14	Benzopyran derivate

Country Status (17)

Country	Link
US (1)	US6589983B1 (de)
EP (1)	EP1212314B1 (de)
KR (1)	KR100766676B1 (de)
CN (1)	CN1167697C (de)
AT (1)	ATE311378T1 (de)
AU (1)	AU766935B2 (de)
CA (1)	CA2383583C (de)
CZ (1)	CZ2002802A3 (de)
DE (1)	DE60024471T2 (de)
HK (1)	HK1047106B (de)
HU (1)	HUP0202690A3 (de)
IL (2)	IL147968A0 (de)
NO (1)	NO328013B1 (de)
NZ (1)	NZ517404A (de)
RU (1)	RU2234502C2 (de)
SK (1)	SK3292002A3 (de)
WO (1)	WO2001021610A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW589305B (en) *	2001-02-14	2004-06-01	Nissan Chemical Ind Ltd	4-aminobenzopyran derivatives
FI20011507A0 (fi)	2001-07-10	2001-07-10	Orion Corp	Uusia yhdisteitä
JP2005505586A (ja) *	2001-10-04	2005-02-24	ワイス	５−ヒドロキシトリプタミン−６リガンドとしてのクロマン誘導体
KR101078357B1 (ko) *	2002-08-29	2011-10-31	닛산 가가쿠 고교 가부시키 가이샤	아미노벤조피란 화합물의 제조방법
FI20030030A0 (fi)	2003-01-09	2003-01-09	Orion Corp	Uusia yhdisteitä
GB0315950D0 (en)	2003-06-11	2003-08-13	Xention Discovery Ltd	Compounds
TWI346112B (en) *	2004-02-25	2011-08-01	Nissan Chemical Ind Ltd	Benzopyran compound
ES2353021T3 (es)	2004-03-23	2011-02-24	Nissan Chemical Industries, Ltd.	Compuesto de benzopirano tricíclico como agentes anti-arrítmicos.
GB0412986D0 (en)	2004-06-10	2004-07-14	Xention Discovery Ltd	Compounds
US7576212B2 (en)	2004-12-09	2009-08-18	Xention Limited	Thieno[2,3-B] pyridines as potassium channel inhibitors
CA2591810A1 (en) *	2004-12-21	2006-06-29	F.Hoffmann-La Roche Ag	Chroman derivatives and uses thereof in the treatment of cns disorders
GB0525164D0 (en)	2005-12-09	2006-01-18	Xention Discovery Ltd	Compounds
RU2448112C2 (ru) *	2006-03-10	2012-04-20	Ниссан Кемикал Индастриз, Лтд.	Способ получения оптически активного соединения оксида хромена
GB0815784D0 (en)	2008-08-29	2008-10-08	Xention Ltd	Novel potassium channel blockers
GB0815781D0 (en)	2008-08-29	2008-10-08	Xention Ltd	Novel potassium channel blockers
GB0815782D0 (en)	2008-08-29	2008-10-08	Xention Ltd	Novel potassium channel blockers
AU2011274369A1 (en) *	2010-07-02	2012-12-06	Ventana Medical Systems, Inc.	Hapten conjugates for target detection
GB201105659D0 (en)	2011-04-01	2011-05-18	Xention Ltd	Compounds
NO3175985T3 (de)	2011-07-01	2018-04-28
AR090037A1 (es)	2011-11-15	2014-10-15	Xention Ltd	Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
JP2014533258A (ja)	2011-11-15	2014-12-11	ゼンション・リミテッドＸｅｎｔｉｏｎＬｉｍｉｔｅｄ	カリウムチャネル阻害剤としてのチエノ［２，３−ｃ］ピラゾールの使用
HK1201455A1 (en)	2012-01-27	2015-09-04	Gilead Sciences Inc	Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
US20220071951A1 (en)	2018-12-28	2022-03-10	Osaka University	Therapeutic agent for inherited bradyarrhythmia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9005318D0 (en)	1990-03-09	1990-05-02	Isis Innovation	Antiarrhythmic agents
AU651105B2 (en) *	1990-06-18	1994-07-14	E.R. Squibb & Sons, Inc.	Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
GB9301611D0 (en) *	1993-08-04	1993-08-04	Parisella Gerald	Dexterity game
CZ24499A3 (cs) *	1996-07-26	1999-05-12	Nissan Chemical Industries, Ltd.	Derivát chromanu a farmaceutický prostředek, který ho obsahuje

2000
- 2000-09-14 CA CA002383583A patent/CA2383583C/en not_active Expired - Fee Related
- 2000-09-14 DE DE60024471T patent/DE60024471T2/de not_active Expired - Lifetime
- 2000-09-14 HK HK02108750.1A patent/HK1047106B/en not_active IP Right Cessation
- 2000-09-14 US US10/048,026 patent/US6589983B1/en not_active Expired - Fee Related
- 2000-09-14 AT AT00961032T patent/ATE311378T1/de not_active IP Right Cessation
- 2000-09-14 SK SK329-2002A patent/SK3292002A3/sk unknown
- 2000-09-14 IL IL14796800A patent/IL147968A0/xx active IP Right Grant
- 2000-09-14 RU RU2002110115/04A patent/RU2234502C2/ru not_active IP Right Cessation
- 2000-09-14 NZ NZ517404A patent/NZ517404A/xx unknown
- 2000-09-14 EP EP00961032A patent/EP1212314B1/de not_active Expired - Lifetime
- 2000-09-14 CN CNB008129509A patent/CN1167697C/zh not_active Expired - Fee Related
- 2000-09-14 CZ CZ2002802A patent/CZ2002802A3/cs unknown
- 2000-09-14 AU AU73143/00A patent/AU766935B2/en not_active Ceased
- 2000-09-14 KR KR1020027003510A patent/KR100766676B1/ko not_active Expired - Fee Related
- 2000-09-14 HU HU0202690A patent/HUP0202690A3/hu unknown
- 2000-09-14 WO PCT/JP2000/006323 patent/WO2001021610A1/en not_active Ceased
2002
- 2002-02-03 IL IL147968A patent/IL147968A/en not_active IP Right Cessation
- 2002-03-15 NO NO20021294A patent/NO328013B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU766935B2 (en)	2003-10-23
US6589983B1 (en)	2003-07-08
RU2234502C2 (ru)	2004-08-20
KR20020068505A (ko)	2002-08-27
CN1374957A (zh)	2002-10-16
CA2383583C (en)	2009-04-07
IL147968A (en)	2006-04-10
DE60024471D1 (de)	2006-01-05
NO20021294D0 (no)	2002-03-15
CA2383583A1 (en)	2001-03-29
HK1047106B (en)	2006-04-28
HUP0202690A3 (en)	2005-02-28
HUP0202690A2 (hu)	2002-12-28
DE60024471T2 (de)	2006-08-03
EP1212314B1 (de)	2005-11-30
AU7314300A (en)	2001-04-24
CZ2002802A3 (cs)	2003-02-12
CN1167697C (zh)	2004-09-22
EP1212314A1 (de)	2002-06-12
NO20021294L (no)	2002-03-15
SK3292002A3 (en)	2003-04-01
IL147968A0 (en)	2002-09-12
HK1047106A1 (en)	2003-02-07
NO328013B1 (no)	2009-11-09
KR100766676B1 (ko)	2007-10-15
NZ517404A (en)	2003-01-31
WO2001021610A1 (en)	2001-03-29

Legal Events

Date	Code	Title	Description
2006-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE311378T1 (de)	2005-12-15	Benzopyran derivate
SE0202133D0 (sv)	2002-07-08	Novel compounds
ATE338461T1 (de)	2006-09-15	Pyrazolpyrimidinfungizide
PL365007A1 (en)	2004-12-27	Pharmaceutical compositions containing 3-amino-azetidine derivatives, novel derivatives and preparation thereof
AR036042A1 (es)	2004-08-04	Derivados aralquilsufonil-3-(pirrol-2-ilmetiliden)-2-indolinona, sus composiciones farmaceuticas y metodo para la modulacion de la actividad catalitica de una proteina quinasa
CY1106522T1 (el)	2012-01-25	Ετepοκυκλικη ενωση και αντικαρκινικο μεσο που πepιεχει την ιδια ως δραστικο συστατικο
ATE302775T1 (de)	2005-09-15	Carbolinderivate
WO2003016291A1 (en)	2003-02-27	ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR δ
MXPA03011638A (es)	2004-04-02	Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
MY136855A (en)	2008-11-28	Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
TR200103497T2 (tr)	2002-05-21	Beta2-adrenoseptör agonistler.
DK2314582T3 (da)	2014-06-10	Heterocykliske forbindelser som antivirusmidler
ATE296826T1 (de)	2005-06-15	Pyrazolo(1,5)pyridinderivate
HUP0301607A2 (hu)	2003-12-29	Szelektív neurokinin antagonista hatású nitrogéntartalmú heterociklusos vegyületek, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
WO2007071632A3 (en)	2007-08-30	2-pyridin-2-yl-quinazoline derivatives as potassium channel modulating agents for the treatment of respiratory diseases
ATE346067T1 (de)	2006-12-15	Carbolinderivate
ATE300541T1 (de)	2005-08-15	Pyrazolopyridinderivate
SE0303541D0 (sv)	2003-12-22	New compounds
MY139612A (en)	2009-10-30	Benzoxazine derivatives as 5-th6 modulators and uses thereof
EP0765865A4 (de)	1997-08-13	2-acylaminopropanolverbindungen und medizinische zusammensetzungen
MY136824A (en)	2008-11-28	Substituted benzoxazinones and uses thereof
AR027296A1 (es)	2003-03-19	Derivados de 4-heteroaril-1,4-diazabiciclo[3.2.2]nonano, su preparacion y su aplicacion terapeutica
DE60206505D1 (de)	2006-02-16	Substituierte benzopyran derivate gegen arrhythmie
PT947513E (pt)	2004-09-30	Derivados de amina triciclicos
SE0303090D0 (sv)	2003-11-20	Novel compounds