ATE311832T1 - Verkalkungswiderstandsfähiges bioprothetisches gewebe und herstellungsverfahren - Google Patents

Verkalkungswiderstandsfähiges bioprothetisches gewebe und herstellungsverfahren

Info

Publication number
ATE311832T1
ATE311832T1 AT95938792T AT95938792T ATE311832T1 AT E311832 T1 ATE311832 T1 AT E311832T1 AT 95938792 T AT95938792 T AT 95938792T AT 95938792 T AT95938792 T AT 95938792T AT E311832 T1 ATE311832 T1 AT E311832T1
Authority
AT
Austria
Prior art keywords
tissue
crosslinked
calcification
production method
bioprosthetic tissue
Prior art date
Application number
AT95938792T
Other languages
English (en)
Inventor
Robert J Levy
Eyal Lerner
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of ATE311832T1 publication Critical patent/ATE311832T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/92—Method or apparatus for preparing or treating prosthetic
    • Y10S623/921—Blood vessel

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
AT95938792T 1994-10-21 1995-10-20 Verkalkungswiderstandsfähiges bioprothetisches gewebe und herstellungsverfahren ATE311832T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32735994A 1994-10-21 1994-10-21
PCT/US1995/013443 WO1996013227A1 (en) 1994-10-21 1995-10-20 Calcification-resistant bioprosthetic tissue and methods of making same

Publications (1)

Publication Number Publication Date
ATE311832T1 true ATE311832T1 (de) 2005-12-15

Family

ID=23276227

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95938792T ATE311832T1 (de) 1994-10-21 1995-10-20 Verkalkungswiderstandsfähiges bioprothetisches gewebe und herstellungsverfahren

Country Status (14)

Country Link
US (1) US5674298A (de)
EP (1) EP0786970B1 (de)
JP (1) JPH10507673A (de)
CN (1) CN1200655C (de)
AT (1) ATE311832T1 (de)
AU (1) AU713605B2 (de)
BR (1) BR9509473A (de)
CA (1) CA2202247A1 (de)
DE (1) DE69534671T2 (de)
IL (1) IL115708A (de)
NO (1) NO971744D0 (de)
NZ (1) NZ296283A (de)
WO (1) WO1996013227A1 (de)
ZA (1) ZA958900B (de)

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US6214054B1 (en) * 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
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Also Published As

Publication number Publication date
EP0786970B1 (de) 2005-12-07
CN1200655C (zh) 2005-05-11
NZ296283A (en) 1999-11-29
DE69534671D1 (de) 2006-01-12
BR9509473A (pt) 1997-09-30
ZA958900B (en) 1997-04-15
DE69534671T2 (de) 2006-07-13
CN1162252A (zh) 1997-10-15
EP0786970A1 (de) 1997-08-06
IL115708A (en) 2000-11-21
US5674298A (en) 1997-10-07
CA2202247A1 (en) 1996-05-09
EP0786970A4 (de) 2000-04-05
AU713605B2 (en) 1999-12-09
WO1996013227A1 (en) 1996-05-09
NO971744L (no) 1997-04-16
JPH10507673A (ja) 1998-07-28
IL115708A0 (en) 1996-08-04
NO971744D0 (no) 1997-04-16
AU4003795A (en) 1996-05-23

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