ATE311892T1 - Hochaktive immunstimulierende mittel aus mikroalgen - Google Patents

Hochaktive immunstimulierende mittel aus mikroalgen

Info

Publication number
ATE311892T1
ATE311892T1 AT01952597T AT01952597T ATE311892T1 AT E311892 T1 ATE311892 T1 AT E311892T1 AT 01952597 T AT01952597 T AT 01952597T AT 01952597 T AT01952597 T AT 01952597T AT E311892 T1 ATE311892 T1 AT E311892T1
Authority
AT
Austria
Prior art keywords
microalgae
ethanol
immunstimulants
extraction
immunostimulatory
Prior art date
Application number
AT01952597T
Other languages
English (en)
Inventor
David Stanley Pasco
Nirmal Pugh
Samir Ross
Mahmoud Elsohly
Original Assignee
Univ Mississippi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mississippi filed Critical Univ Mississippi
Application granted granted Critical
Publication of ATE311892T1 publication Critical patent/ATE311892T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Oncology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01952597T 2000-07-10 2001-07-10 Hochaktive immunstimulierende mittel aus mikroalgen ATE311892T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21700100P 2000-07-10 2000-07-10
PCT/US2001/021770 WO2002004000A1 (en) 2000-07-10 2001-07-10 Potent immunostimulants from microalgae

Publications (1)

Publication Number Publication Date
ATE311892T1 true ATE311892T1 (de) 2005-12-15

Family

ID=22809278

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01952597T ATE311892T1 (de) 2000-07-10 2001-07-10 Hochaktive immunstimulierende mittel aus mikroalgen

Country Status (20)

Country Link
US (2) US7205284B2 (de)
EP (1) EP1301191B1 (de)
JP (1) JP2004502737A (de)
KR (1) KR100831408B1 (de)
CN (2) CN1823848A (de)
AT (1) ATE311892T1 (de)
AU (2) AU2001273330C1 (de)
BR (1) BR0112424A (de)
CA (1) CA2412600C (de)
DE (1) DE60115654T2 (de)
DK (1) DK1301191T3 (de)
EA (1) EA006318B1 (de)
ES (1) ES2254451T3 (de)
IL (2) IL153503A0 (de)
MX (1) MXPA03000220A (de)
NO (1) NO329221B1 (de)
NZ (1) NZ523695A (de)
PL (1) PL203814B1 (de)
WO (1) WO2002004000A1 (de)
ZA (1) ZA200301050B (de)

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EP1307213B1 (de) 2000-08-10 2004-04-28 Ocean Nutrition Canada Ltd. Chlorella zubereitungen mit immunmodulatorischen eigenschaften
US6814961B1 (en) 2001-05-14 2004-11-09 Gitte S. Jensen Method for enhancing stem cell trafficking
EP1478648B1 (de) 2002-02-01 2014-04-30 ARIAD Pharmaceuticals, Inc. Phosphorhaltige verbindungen und deren verwendungen
FR2850277B1 (fr) * 2003-01-24 2005-04-08 Lanatech Composition comprenant un extrait d'aphanizomenon flos-aquae, son utilisation et sa preparation
NO320429B1 (no) * 2003-06-03 2005-12-05 Sinvent As Farmasoytisk blanding for forokning av motstanden mot sykdommer forarsaket av patogene mikroorganismer og anvendelse av glukan for fremstilling av en farmasoytisk blanding.
US7846452B2 (en) * 2004-07-30 2010-12-07 The University Of Mississippi Potent immunostimulatory extracts from microalgae
RU2417093C2 (ru) * 2005-06-24 2011-04-27 Дезерт Лейк Текнолоджиз Очищенный компонент цианобактерий и способ применения
AU2007264043B2 (en) * 2006-06-27 2012-03-15 Nutratec S.R.L. Extracts of Aphanizomenon Flos Aquae and nutritional, cosmetic and pharmaceutical compositions containing the same
US20100003275A1 (en) * 2006-09-08 2010-01-07 The University Of Mississippi Immunostimulatory Composition comprising Lipoprotein in Microalgae Extract
CA2723484A1 (en) * 2008-05-06 2009-11-12 Ocean Nutrition Canada Limited Compositions obtained from chlorella extract having immunomodulating properties
US8211308B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8475660B2 (en) 2010-04-06 2013-07-02 Heliae Development, Llc Extraction of polar lipids by a two solvent method
US8313648B2 (en) 2010-04-06 2012-11-20 Heliae Development, Llc Methods of and systems for producing biofuels from algal oil
US8308951B1 (en) 2010-04-06 2012-11-13 Heliae Development, Llc Extraction of proteins by a two solvent method
US8115022B2 (en) 2010-04-06 2012-02-14 Heliae Development, Llc Methods of producing biofuels, chlorophylls and carotenoids
AU2011237710A1 (en) 2010-04-06 2012-10-18 Heliae Development, Llc Methods of and systems for producing biofuels
US8202425B2 (en) 2010-04-06 2012-06-19 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8273248B1 (en) 2010-04-06 2012-09-25 Heliae Development, Llc Extraction of neutral lipids by a two solvent method
US8211309B2 (en) 2010-04-06 2012-07-03 Heliae Development, Llc Extraction of proteins by a two solvent method
US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
US9217119B2 (en) 2011-11-28 2015-12-22 Southwest Research Institute Extraction of lipids from living cells utilizing liquid CO2
GB201208325D0 (en) * 2012-05-11 2012-06-27 Glycomar Ltd Saccharides
CN103463141A (zh) * 2013-09-22 2013-12-25 汤永强 一种小球藻喷剂
KR20150102308A (ko) 2014-02-28 2015-09-07 주식회사 코아로직 키터치 인지 가능한 터치패널
EP3034612A1 (de) 2014-12-16 2016-06-22 Greenaltech, S.L. Chitin- und Chitosanherstellungsverfahren
JP6788882B2 (ja) 2016-08-09 2020-11-25 イマジン・グローバル・ケア株式会社 自然免疫活性化作用を有する多糖類及び該多糖類を含有する自然免疫活性化剤又は飲食品
EP3524254A4 (de) * 2016-09-14 2020-11-11 Tes Holdings Co., Ltd. Lin28a-aktivator und verwendung davon
CN107625783A (zh) * 2017-08-09 2018-01-26 天津科技大学 硫酸酯化小球藻、螺旋藻复合多糖在免疫调节领域的应用
SG11202001154QA (en) 2017-08-30 2020-03-30 Far East Bio Tec Co Ltd Cyanobacterial extracts, processes for preparing the same and uses thereof
EP4025181A1 (de) 2019-09-06 2022-07-13 Beautypaste LLC Verbesserte zahnpasta und kits
CN110742900B (zh) * 2019-11-22 2022-06-14 湘潭大学 一种具有免疫调节活性的小球藻胞外多糖复合物及其制备方法和应用
CN111205376B (zh) * 2020-01-07 2021-11-02 华侨大学 一种疣荔枝螺多糖的制备方法及其应用
US12599657B2 (en) 2020-07-02 2026-04-14 Zivo Bioscience, Inc. Enhancement of vaccine efficacy via biomass and/or related material in animal drink and feed
FR3121351B1 (fr) 2021-03-30 2024-03-08 Axeen Pharma Composition à base de spiruline et ses utilisations pour le renforcement de l’immunité
CN114195907B (zh) * 2021-10-20 2022-10-21 中国科学院南海海洋研究所 一种低分子量螺旋藻多糖及其制备方法和应用
CN114544527B (zh) * 2022-01-26 2023-05-02 浙江夸克生物科技有限公司 一种涎液化糖链抗原kl-6测定试剂盒及其制备方法
WO2023192811A1 (en) * 2022-03-30 2023-10-05 Om Biome, Inc. Method for tissue renewal using a microalgae-based biologically friendly base formula to reverse disease progression and foster tissue regeneration in conditions of mucosal injury and inflammation in the mouth and gastrointestinal tract

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US3462412A (en) 1966-04-20 1969-08-19 Tohoku Yakult Seizo Kk Process of producing an active substance for stimulating the function of the reticulo-endothelial system
JPS5896025A (ja) * 1981-12-02 1983-06-07 Kitasato Inst:The 新規生理活性物質ｃｈ−１およびその製造法
HU188311B (en) * 1982-03-04 1986-04-28 Szendrei,Kalman,Hu Process for producing biologically active polisaccharide concentrates and pharmaceutical compositions containing them as active agents
JPS6178729A (ja) * 1984-09-26 1986-04-22 Nisshin Oil Mills Ltd:The 免疫賦活化作用成分
JPS61167620A (ja) * 1985-01-19 1986-07-29 Toa Nenryo Kogyo Kk 多糖類を含んで成る抗癌剤
JPS61197525A (ja) * 1985-02-27 1986-09-01 Nisshin Oil Mills Ltd:The 抗腫瘍活性をもつ免疫賦活化剤
JPS6219528A (ja) 1985-07-16 1987-01-28 Kurorera Kogyo Kk 制癌剤
CA1332650C (en) * 1987-06-18 1994-10-18 Kunitaka Hirose Polysaccharides and antiviral drugs containing the same as active ingredient
US5084386A (en) * 1989-03-31 1992-01-28 Sri International Production of beta-1,3-glucan in euglena
JPH06253881A (ja) * 1993-03-01 1994-09-13 Kurorera Kogyo Kk 糖タンパク複合体およびその製造方法
JP3020387B2 (ja) * 1993-07-27 2000-03-15 日石三菱株式会社 抗ウイルス物質
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Also Published As

Publication number Publication date
ZA200301050B (en) 2004-05-06
KR100831408B1 (ko) 2008-05-21
NO20026130L (no) 2003-03-10
AU7333001A (en) 2002-01-21
AU2001273330C1 (en) 2006-01-12
NO20026130D0 (no) 2002-12-19
CA2412600C (en) 2011-09-27
EA200300123A1 (ru) 2004-02-26
MXPA03000220A (es) 2003-10-15
US20070059317A1 (en) 2007-03-15
DE60115654D1 (de) 2006-01-12
EP1301191B1 (de) 2005-12-07
WO2002004000A1 (en) 2002-01-17
NO329221B1 (no) 2010-09-13
JP2004502737A (ja) 2004-01-29
CN1823848A (zh) 2006-08-30
PL203814B1 (pl) 2009-11-30
US20070264271A1 (en) 2007-11-15
EP1301191A4 (de) 2004-02-25
IL153503A0 (en) 2003-07-06
CN1278691C (zh) 2006-10-11
BR0112424A (pt) 2003-07-01
DE60115654T2 (de) 2006-09-07
CA2412600A1 (en) 2002-01-17
NZ523695A (en) 2004-07-30
DK1301191T3 (da) 2006-05-22
EP1301191A1 (de) 2003-04-16
IL153503A (en) 2008-11-26
EA006318B1 (ru) 2005-10-27
PL359269A1 (en) 2004-08-23
AU2001273330B2 (en) 2005-07-28
US7205284B2 (en) 2007-04-17
ES2254451T3 (es) 2006-06-16
KR20030069974A (ko) 2003-08-27
CN1447695A (zh) 2003-10-08

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