ATE312096T1 - Neue verbindungen - Google Patents
Neue verbindungenInfo
- Publication number
- ATE312096T1 ATE312096T1 AT02792158T AT02792158T ATE312096T1 AT E312096 T1 ATE312096 T1 AT E312096T1 AT 02792158 T AT02792158 T AT 02792158T AT 02792158 T AT02792158 T AT 02792158T AT E312096 T1 ATE312096 T1 AT E312096T1
- Authority
- AT
- Austria
- Prior art keywords
- new connections
- thienylsulphonamides
- pyrazinyl
- asthma
- formula
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- DHDNAPRQADGHLR-UHFFFAOYSA-N n-pyrazin-2-ylthiophene-2-sulfonamide Chemical class C=1C=CSC=1S(=O)(=O)NC1=CN=CC=N1 DHDNAPRQADGHLR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0104474A SE0104474D0 (sv) | 2001-12-18 | 2001-12-18 | Novel Compounds |
| SE0202139A SE0202139D0 (sv) | 2002-07-05 | 2002-07-05 | Novel compounds |
| PCT/SE2002/002355 WO2003051870A1 (en) | 2001-12-18 | 2002-12-17 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312096T1 true ATE312096T1 (de) | 2005-12-15 |
Family
ID=26655646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02792158T ATE312096T1 (de) | 2001-12-18 | 2002-12-17 | Neue verbindungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7410972B2 (de) |
| EP (1) | EP1458715B1 (de) |
| JP (1) | JP2005516936A (de) |
| AT (1) | ATE312096T1 (de) |
| AU (1) | AU2002358390A1 (de) |
| DE (1) | DE60207890T2 (de) |
| WO (1) | WO2003051870A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI328007B (en) | 2002-01-16 | 2010-08-01 | Astrazeneca Ab | Novel compounds |
| DE10260003A1 (de) * | 2002-12-20 | 2004-07-08 | Zf Friedrichshafen Ag | Radnabenantrieb |
| SE0301653D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| SE0302304D0 (sv) * | 2003-08-27 | 2003-08-27 | Astrazeneca Ab | Novel compounds |
| EP1661889A4 (de) * | 2003-09-05 | 2009-08-05 | Ono Pharmaceutical Co | Chemokinrezeptorantagonist und dessen medizinische verwendung |
| ATE519488T1 (de) * | 2004-12-27 | 2011-08-15 | Novartis Ag | Aminopyrazin-analoga zur behandlung von glaukomen und anderen durch rho-kinase verursachten krankheiten |
| US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
| DK2354126T3 (da) * | 2005-01-14 | 2014-01-13 | Chemocentryx Inc | Heteroarylsulfonamider og ccr2 |
| TWI422376B (zh) | 2005-01-25 | 2014-01-11 | Synta Pharmaceuticals Corp | 用於炎症及免疫相關用途之化合物 |
| GB0514743D0 (en) * | 2005-07-19 | 2005-08-24 | Astrazeneca Ab | Salt |
| TW200800921A (en) * | 2005-09-19 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
| US20090182142A1 (en) * | 2005-12-02 | 2009-07-16 | Shigeru Furukubo | Aromatic Compound |
| EP1970373A1 (de) * | 2005-12-02 | 2008-09-17 | Mitsubishi Tanabe Pharma Corporation | Alicyclische heterocyclische verbindung |
| TW200730512A (en) * | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
| GB0526445D0 (en) * | 2005-12-23 | 2006-02-08 | Novartis Ag | Organic compounds |
| JP5508027B2 (ja) | 2007-02-22 | 2014-05-28 | メルク セローノ ソシエテ アノニム | キノキサリン化合物及びその使用 |
| CA2692761C (en) | 2007-07-12 | 2013-04-30 | Chemocentryx, Inc. | Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation |
| PT2374802E (pt) | 2008-11-10 | 2014-07-10 | Kyowa Hakko Kirin Co Ltd | Inibidor de produção de quinurenina |
| TWI535442B (zh) | 2010-05-10 | 2016-06-01 | Kyowa Hakko Kirin Co Ltd | A nitrogen-containing heterocyclic compound having an action of inhibiting the production of canine erythritine |
| US20130211076A1 (en) | 2010-10-20 | 2013-08-15 | Merck Serono S.A. Geneva | Method for preparing substituted N-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates N-(3-chloro-quinoxalin-2-yl)-sulfonamides |
| WO2013069765A1 (ja) | 2011-11-09 | 2013-05-16 | 協和発酵キリン株式会社 | 含窒素複素環化合物 |
| CN105377837B (zh) * | 2013-05-14 | 2017-08-04 | 活跃生物技术有限公司 | 用作s100‑抑制剂的n‑(杂芳基)磺酰胺衍生物 |
| MX388165B (es) | 2016-11-23 | 2025-03-19 | Chemocentryx Inc | Método para tratar glomeruloesclerosis segmentaria focal |
| BR112020007183A2 (pt) | 2017-10-11 | 2020-09-24 | Chemocentryx, Inc. | tratamento de glomeruloesclerose focal segmentado com antagonistas de ccr2 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962490A (en) * | 1987-09-25 | 1999-10-05 | Texas Biotechnology Corporation | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin |
| CA2162630C (en) | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
| EP1541563A4 (de) | 2002-07-10 | 2007-11-07 | Ono Pharmaceutical Co | Ccr4-antagonist und dessen medizinische verwendung |
-
2002
- 2002-12-17 AT AT02792158T patent/ATE312096T1/de not_active IP Right Cessation
- 2002-12-17 WO PCT/SE2002/002355 patent/WO2003051870A1/en not_active Ceased
- 2002-12-17 EP EP02792158A patent/EP1458715B1/de not_active Expired - Lifetime
- 2002-12-17 DE DE60207890T patent/DE60207890T2/de not_active Expired - Fee Related
- 2002-12-17 JP JP2003552754A patent/JP2005516936A/ja active Pending
- 2002-12-17 US US10/499,102 patent/US7410972B2/en not_active Expired - Fee Related
- 2002-12-17 AU AU2002358390A patent/AU2002358390A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60207890D1 (de) | 2006-01-12 |
| US7410972B2 (en) | 2008-08-12 |
| US20050075346A1 (en) | 2005-04-07 |
| DE60207890T2 (de) | 2006-08-10 |
| AU2002358390A1 (en) | 2003-06-30 |
| EP1458715B1 (de) | 2005-12-07 |
| EP1458715A1 (de) | 2004-09-22 |
| JP2005516936A (ja) | 2005-06-09 |
| WO2003051870A1 (en) | 2003-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |