ATE403657T1 - Chemische verbindungen - Google Patents

Chemische verbindungen

Info

Publication number
ATE403657T1
ATE403657T1 AT02776075T AT02776075T ATE403657T1 AT E403657 T1 ATE403657 T1 AT E403657T1 AT 02776075 T AT02776075 T AT 02776075T AT 02776075 T AT02776075 T AT 02776075T AT E403657 T1 ATE403657 T1 AT E403657T1
Authority
AT
Austria
Prior art keywords
chemical compounds
derivatives
methods
pyrazolo
diseases
Prior art date
Application number
AT02776075T
Other languages
English (en)
Inventor
Jerry Adams
Jiri Kasparec
Domingos Silva
Catherine Yuan
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE403657T1 publication Critical patent/ATE403657T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02776075T 2001-10-02 2002-10-01 Chemische verbindungen ATE403657T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32650601P 2001-10-02 2001-10-02

Publications (1)

Publication Number Publication Date
ATE403657T1 true ATE403657T1 (de) 2008-08-15

Family

ID=23272496

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02776075T ATE403657T1 (de) 2001-10-02 2002-10-01 Chemische verbindungen

Country Status (8)

Country Link
US (1) US7217710B2 (de)
EP (1) EP1432714B1 (de)
JP (1) JP4459619B2 (de)
AT (1) ATE403657T1 (de)
AU (1) AU2002341920A1 (de)
DE (1) DE60228103D1 (de)
ES (1) ES2309206T3 (de)
WO (1) WO2003029209A2 (de)

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EP1863805A1 (de) * 2005-02-01 2007-12-12 AstraZeneca AB Pyrimidinverbindungen mit tie2- (tek-) hemmender wirkung
US20080146599A1 (en) * 2005-02-01 2008-06-19 Astrazeneca Ab Pyrimidine Compounds Having Tie-2 (Tek) Inhibitory Activity
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US8008035B2 (en) 2007-01-25 2011-08-30 Roche Diagnostics Operations, Inc. Enhancement of vanadium-containing phosphatase inhibitors
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US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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US8759359B2 (en) 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
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US9290499B2 (en) 2010-05-19 2016-03-22 The University Of North Carolina At Chapel Hill Pyrazolopyrimidine compounds for the treatment of cancer
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WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
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AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
AU2013266438B2 (en) 2012-05-22 2017-09-07 The University Of North Carolina At Chapel Hill Pyrimidine compounds for the treatment of cancer
EP2909211A4 (de) 2012-10-17 2016-06-22 Univ North Carolina Pyrazolopyrimidinverbindungen zur krebsbehandlung
EP2925752A4 (de) 2012-11-27 2016-06-01 Univ North Carolina Pyrimidinverbindungen zur krebsbehandlung
TWI629275B (zh) * 2013-03-13 2018-07-11 賽諾菲公司 Ｎ－（４－（氮雜吲唑－６－基）－苯基）－磺醯胺及其作為醫藥之用途
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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
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MX386697B (es) 2014-01-21 2025-03-19 Janssen Pharmaceutica Nv Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso
US9555031B2 (en) 2014-04-11 2017-01-31 The University Of North Carolina At Chapel Hill Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity
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Also Published As

Publication number Publication date
EP1432714A2 (de) 2004-06-30
US7217710B2 (en) 2007-05-15
EP1432714A4 (de) 2005-10-19
JP4459619B2 (ja) 2010-04-28
ES2309206T3 (es) 2008-12-16
US20040198751A1 (en) 2004-10-07
AU2002341920A1 (en) 2003-04-14
EP1432714B1 (de) 2008-08-06
JP2005504828A (ja) 2005-02-17
DE60228103D1 (de) 2008-09-18
WO2003029209A2 (en) 2003-04-10
WO2003029209A3 (en) 2004-02-12

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