ATE312097T1 - Polymorphe und andere kristalline formen von cis- ftc - Google Patents

Polymorphe und andere kristalline formen von cis- ftc

Info

Publication number
ATE312097T1
ATE312097T1 AT02748367T AT02748367T ATE312097T1 AT E312097 T1 ATE312097 T1 AT E312097T1 AT 02748367 T AT02748367 T AT 02748367T AT 02748367 T AT02748367 T AT 02748367T AT E312097 T1 ATE312097 T1 AT E312097T1
Authority
AT
Austria
Prior art keywords
ftc
cis
forms
manufacture
polymorphods
Prior art date
Application number
AT02748367T
Other languages
English (en)
Inventor
Kenneth R Phares
Devalina Law
Yuerong Hu
Original Assignee
Gilead Sciences Inc
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc, Abbott Lab filed Critical Gilead Sciences Inc
Application granted granted Critical
Publication of ATE312097T1 publication Critical patent/ATE312097T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02748367T 2001-03-01 2002-03-01 Polymorphe und andere kristalline formen von cis- ftc ATE312097T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27256001P 2001-03-01 2001-03-01
US30960501P 2001-08-02 2001-08-02
PCT/US2002/006184 WO2002070518A1 (en) 2001-03-01 2002-03-01 Polymorphic and other crystalline forms of cis-ftc

Publications (1)

Publication Number Publication Date
ATE312097T1 true ATE312097T1 (de) 2005-12-15

Family

ID=26955597

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02748367T ATE312097T1 (de) 2001-03-01 2002-03-01 Polymorphe und andere kristalline formen von cis- ftc
AT05076347T ATE383355T1 (de) 2001-03-01 2002-03-01 Polymorph und andere kristallinische formen von zusammen-ftc

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05076347T ATE383355T1 (de) 2001-03-01 2002-03-01 Polymorph und andere kristallinische formen von zusammen-ftc

Country Status (14)

Country Link
US (3) US6723728B2 (de)
EP (3) EP1389207B1 (de)
JP (4) JP5105689B2 (de)
KR (4) KR100927024B1 (de)
CN (4) CN102942563A (de)
AT (2) ATE312097T1 (de)
AU (1) AU2002335489B2 (de)
CA (4) CA2788498C (de)
CY (2) CY1107983T1 (de)
DE (2) DE60224592T2 (de)
DK (2) DK1389207T3 (de)
ES (3) ES2537007T3 (de)
PT (2) PT1574512E (de)
WO (1) WO2002070518A1 (de)

Families Citing this family (11)

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CN102942563A (zh) * 2001-03-01 2013-02-27 基利得科学公司 顺-ftc的多晶型物及其它晶型
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DK1583542T3 (da) 2003-01-14 2008-09-22 Gilead Sciences Inc Sammensætninger og fremgangsmåder til antiviral kombinationsterapi
US6943249B2 (en) * 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) * 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
WO2009005338A2 (en) * 2007-07-05 2009-01-08 Ultimorphix Technologies B.V. Solid forms ult-i, ult-2 and ult-3 of emtricitabine
EP2350065A1 (de) 2008-11-12 2011-08-03 Lupin Ltd. Neues polymorph von emtricitabin und verfahren zu dessen herstellung
EP2454244B1 (de) 2009-07-15 2013-06-26 Lupin Limited Verbessertes verfahren zur herstellung von efavirenz

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Also Published As

Publication number Publication date
EP1903041B1 (de) 2015-02-18
CN102911166A (zh) 2013-02-06
JP2004530660A (ja) 2004-10-07
KR101015510B1 (ko) 2011-02-16
ES2537007T3 (es) 2015-06-01
JP5105689B2 (ja) 2012-12-26
US20050026934A1 (en) 2005-02-03
KR20080065316A (ko) 2008-07-11
KR20100091265A (ko) 2010-08-18
JP2015028045A (ja) 2015-02-12
DE60207850D1 (de) 2006-01-12
US7544692B2 (en) 2009-06-09
EP1389207A1 (de) 2004-02-18
PT1574512E (pt) 2008-03-05
AU2002335489B2 (en) 2008-06-05
CA2439831C (en) 2010-01-12
CN102911165A (zh) 2013-02-06
EP1574512B1 (de) 2008-01-09
US20030060645A1 (en) 2003-03-27
CA2788498C (en) 2016-02-16
CY1107983T1 (el) 2013-09-04
CN102911166B (zh) 2016-08-17
WO2002070518A1 (en) 2002-09-12
CA2439831A1 (en) 2002-09-12
US8637535B2 (en) 2014-01-28
JP2009197005A (ja) 2009-09-03
CN102911165B (zh) 2016-08-17
CN102942563A (zh) 2013-02-27
EP1903041A2 (de) 2008-03-26
JP2013040192A (ja) 2013-02-28
KR20040002871A (ko) 2004-01-07
EP1574512A1 (de) 2005-09-14
PT1903041E (pt) 2015-06-23
CY1107913T1 (el) 2013-09-04
DE60224592D1 (de) 2008-02-21
ES2253544T3 (es) 2006-06-01
DK1574512T3 (da) 2008-03-03
KR20080065317A (ko) 2008-07-11
CN1503796A (zh) 2004-06-09
CA2690137C (en) 2012-11-13
US20090306114A1 (en) 2009-12-10
CA2867970A1 (en) 2002-09-12
DK1389207T3 (da) 2006-04-18
DE60207850T2 (de) 2006-08-10
ES2299950T3 (es) 2008-06-01
KR100927024B1 (ko) 2009-11-17
EP1903041A3 (de) 2008-04-23
DE60224592T2 (de) 2009-01-29
KR101150250B1 (ko) 2012-06-12
ATE383355T1 (de) 2008-01-15
CN1503796B (zh) 2012-07-04
EP1389207B1 (de) 2005-12-07
CA2788498A1 (en) 2002-09-12
CA2690137A1 (en) 2002-09-12
US6723728B2 (en) 2004-04-20

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