ATE314065T1 - Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung - Google Patents

Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung

Info

Publication number
ATE314065T1
ATE314065T1 AT96937773T AT96937773T ATE314065T1 AT E314065 T1 ATE314065 T1 AT E314065T1 AT 96937773 T AT96937773 T AT 96937773T AT 96937773 T AT96937773 T AT 96937773T AT E314065 T1 ATE314065 T1 AT E314065T1
Authority
AT
Austria
Prior art keywords
methods
threitol
acid esters
useful
compositions containing
Prior art date
Application number
AT96937773T
Other languages
English (en)
Inventor
Guy W Bemis
Pravin R Chaturvedi
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of ATE314065T1 publication Critical patent/ATE314065T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Seasonings (AREA)
  • Dairy Products (AREA)
  • Confectionery (AREA)
AT96937773T 1995-10-30 1996-10-30 Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung ATE314065T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/550,453 US5763488A (en) 1995-10-30 1995-10-30 Methods and compositions using butyrate esters of threitol
PCT/US1996/017244 WO1997016180A1 (en) 1995-10-30 1996-10-30 Methods and compositions using butyrate esters of threitol

Publications (1)

Publication Number Publication Date
ATE314065T1 true ATE314065T1 (de) 2006-01-15

Family

ID=24197246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96937773T ATE314065T1 (de) 1995-10-30 1996-10-30 Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung

Country Status (6)

Country Link
US (2) US5763488A (de)
EP (1) EP0862426B1 (de)
AT (1) ATE314065T1 (de)
AU (1) AU718721B2 (de)
DE (1) DE69635670T2 (de)
WO (1) WO1997016180A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011699A1 (en) * 1993-10-29 1995-05-04 The Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
WO1999040883A2 (en) * 1998-02-11 1999-08-19 Faller Douglas V Compositions and methods for the treatment of cystic fibrosis
IL145509A0 (en) * 1999-03-19 2002-06-30 Vertex Pharma Oral butyrate compositions
IT1320168B1 (it) * 2000-03-13 2003-11-18 Univ Ferrara Oligonucleotidi sintetici in grado di indurre il differenziamentoeritroide.
EP1291015A1 (de) * 2001-09-10 2003-03-12 Lunamed AG Darreichungsformen mit verlängerter Wirkstofffreisetzung
ITTO20010922A1 (it) * 2001-09-27 2003-03-27 Chiesi Farma Spa Derivati 3-deossi-3-ammidici e 3-deossi-3-chetonici di carboidrati come induttori del differenziamento cellulare eritroide.
US20060246161A1 (en) * 2003-02-21 2006-11-02 Hongtao Xing Method of making medicament for treating anemia
WO2006059237A1 (en) * 2004-08-30 2006-06-08 Lunamed, Inc. 4-phenylbutyric acid controlled-release formulations for therapeutic use
DE102005046237A1 (de) * 2005-09-28 2007-04-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen
WO2010105112A1 (en) * 2009-03-11 2010-09-16 Hemaquest Pharmaceuticals, Inc. Detection of short-chain fatty acids in biological samples
US20110086869A1 (en) 2009-09-24 2011-04-14 The Trustees Of Boston University Methods for treating viral disorders
WO2011072086A1 (en) 2009-12-08 2011-06-16 Hemaquest Pharmaceuticals, Inc. Methods and low dose regimens for treating red blood cell disorders
WO2011113013A2 (en) 2010-03-11 2011-09-15 Hemaquest Pharmaceuticals, Inc. Methods and compositions for treating viral or virally-induced conditions
JP7158104B2 (ja) 2016-07-15 2022-10-21 ビラクタ セラピューティクス，インク． Ｎｋ細胞ベースの療法で使用するためのｈｄａｃ阻害剤
KR102708641B1 (ko) 2016-09-27 2024-09-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 미생물유전체를 조정함으로써 면역 체크포인트 차단 요법을 증강시키는 방법
AU2020283590A1 (en) 2019-05-31 2022-01-20 Viracta Subsidiary, Inc. Methods of treating virally associated cancers with histone deacetylase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them
FR2633929B2 (fr) * 1987-09-25 1995-05-24 Picardie Universite Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees
US5569675A (en) * 1994-03-07 1996-10-29 Bar Ilan University Methods of using carboxylic acid esters to increase fetal-hemoglobin levels
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol

Also Published As

Publication number Publication date
US5763488A (en) 1998-06-09
DE69635670D1 (de) 2006-02-02
US5945407A (en) 1999-08-31
WO1997016180A1 (en) 1997-05-09
EP0862426B1 (de) 2005-12-28
EP0862426A1 (de) 1998-09-09
AU7523896A (en) 1997-05-22
DE69635670T2 (de) 2006-09-07
AU718721B2 (en) 2000-04-20

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