ATE314065T1 - Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung - Google Patents

Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung

Info

Publication number
ATE314065T1
ATE314065T1 AT96937773T AT96937773T ATE314065T1 AT E314065 T1 ATE314065 T1 AT E314065T1 AT 96937773 T AT96937773 T AT 96937773T AT 96937773 T AT96937773 T AT 96937773T AT E314065 T1 ATE314065 T1 AT E314065T1
Authority
AT
Austria
Prior art keywords
methods
threitol
acid esters
useful
compositions containing
Prior art date
Application number
AT96937773T
Other languages
English (en)
Inventor
Guy W Bemis
Pravin R Chaturvedi
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of ATE314065T1 publication Critical patent/ATE314065T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Seasonings (AREA)
  • Dairy Products (AREA)
  • Confectionery (AREA)
AT96937773T 1995-10-30 1996-10-30 Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung ATE314065T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/550,453 US5763488A (en) 1995-10-30 1995-10-30 Methods and compositions using butyrate esters of threitol
PCT/US1996/017244 WO1997016180A1 (en) 1995-10-30 1996-10-30 Methods and compositions using butyrate esters of threitol

Publications (1)

Publication Number Publication Date
ATE314065T1 true ATE314065T1 (de) 2006-01-15

Family

ID=24197246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96937773T ATE314065T1 (de) 1995-10-30 1996-10-30 Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung

Country Status (6)

Country Link
US (2) US5763488A (de)
EP (1) EP0862426B1 (de)
AT (1) ATE314065T1 (de)
AU (1) AU718721B2 (de)
DE (1) DE69635670T2 (de)
WO (1) WO1997016180A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU696167B2 (en) * 1993-10-29 1998-09-03 Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol
WO1999040883A2 (en) * 1998-02-11 1999-08-19 Faller Douglas V Compositions and methods for the treatment of cystic fibrosis
CA2366650A1 (en) * 1999-03-19 2000-09-28 Michael Su Oral low dose butyrate compositions
IT1320168B1 (it) * 2000-03-13 2003-11-18 Univ Ferrara Oligonucleotidi sintetici in grado di indurre il differenziamentoeritroide.
EP1291015A1 (de) * 2001-09-10 2003-03-12 Lunamed AG Darreichungsformen mit verlängerter Wirkstofffreisetzung
ITTO20010922A1 (it) * 2001-09-27 2003-03-27 Chiesi Farma Spa Derivati 3-deossi-3-ammidici e 3-deossi-3-chetonici di carboidrati come induttori del differenziamento cellulare eritroide.
US20060246161A1 (en) * 2003-02-21 2006-11-02 Hongtao Xing Method of making medicament for treating anemia
US20060045912A1 (en) * 2004-08-30 2006-03-02 Peter Truog 4-phenylbutyric acid controlled-release formulations for therapeutic use
DE102005046237A1 (de) * 2005-09-28 2007-04-05 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Buttersäureester von Kohlenhydraten und Kohlenhydratpolyolen
WO2010105112A1 (en) * 2009-03-11 2010-09-16 Hemaquest Pharmaceuticals, Inc. Detection of short-chain fatty acids in biological samples
US20110086869A1 (en) 2009-09-24 2011-04-14 The Trustees Of Boston University Methods for treating viral disorders
CN102802412A (zh) 2009-12-08 2012-11-28 海玛奎斯特医药公司 用于治疗红细胞病症的方法及低剂量方案
US20110245154A1 (en) 2010-03-11 2011-10-06 Hemaquest Pharmaceuticals, Inc. Methods and Compositions for Treating Viral or Virally-Induced Conditions
JP7373991B2 (ja) 2016-07-15 2023-11-06 ビラクタ セラピューティクス，インク． 免疫療法で使用するためのヒストン脱アセチル化酵素阻害剤
BR112019006041A2 (pt) 2016-09-27 2019-09-03 Board Of Regents, The University Of Texas System métodos para aprimorar a terapia de bloqueio do ponto de verificação imunológico por modulação do microbioma
SG11202113215UA (en) 2019-05-31 2021-12-30 Viracta Subsidiary Inc Methods of treating virally associated cancers with histone deacetylase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them
FR2633929B2 (fr) * 1987-09-25 1995-05-24 Picardie Universite Derives non toxiques de l'acide n-butyrique, presentant des actions therapeutiques retardees
US5569675A (en) * 1994-03-07 1996-10-29 Bar Ilan University Methods of using carboxylic acid esters to increase fetal-hemoglobin levels
US5763488A (en) * 1995-10-30 1998-06-09 Vertex Pharmaceuticals Incorporated Methods and compositions using butyrate esters of threitol

Also Published As

Publication number Publication date
DE69635670T2 (de) 2006-09-07
US5945407A (en) 1999-08-31
WO1997016180A1 (en) 1997-05-09
AU718721B2 (en) 2000-04-20
AU7523896A (en) 1997-05-22
EP0862426B1 (de) 2005-12-28
DE69635670D1 (de) 2006-02-02
US5763488A (en) 1998-06-09
EP0862426A1 (de) 1998-09-09

Similar Documents

Publication Publication Date Title
ATE314065T1 (de) Threitol-buttersäureester-enthaltende zusammensetzungen und ihre verwendung
TR200000481T2 (tr) N-Alkonoilfenilalenin türevleri.
IT1203515B (it) Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono
PL338857A1 (en) Derivatives of n-arylphenylalanine
FR2710527B1 (fr) Nouvelles compositions cosmétiques et dermatologiques associant céramides et acide linoléique, leur préparation.
AU2118488A (en) Improvements in or relating to methods of treating damaged skin
TW289020B (de)
NO954440D0 (no) 2 pyridylmetylenpolyazamakrocyklo-fosfonsyrer, komplekser og derivater derav, for anvendelse som kontrastmidler
DE68923819D1 (de) Verwendung von gamma-Hydroxy-Buttersäuresalzen zur Herstellung von pharmazeutischen Zusammensetzungen zur Verwendung bei der Behandlung von Alkoholismus und die hergestellten Zusammensetzungen.
DE3875425D1 (de) Vasokinetisch wirkende polyungesaettigte saeuren und sie enthaltende pharmazeutische oder kosmetische zubereitungen.
ATE333275T1 (de) Indole-3-propionsäure, ihre salze und ester als arzneimittel
MY131595A (en) Heterocyclically substituted phenyl-cyclohexane- carboxylic acid derivatives
EP0352581A3 (de) Aethylendiaminmonoamid-Derivate
EP0839529A3 (de) Zubereitungen enthaltend Ester oder Amide von alipatischen Monocarbonsäuren zur Behandlung von Hautkrankheiten
IL105646A0 (en) Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing them
BR9408392A (pt) Derivados de ácidos arilacéticos e sua utilização como fungicidas
ATE172108T1 (de) Verwendung von diglycerinestern gegen unreine haut
ATE223214T1 (de) Von milchsäure abgeleitete butyrat-prodrugs
DE69612671D1 (de) Butyrat-medikamentvorstufen der milchsäure
DE59401990D1 (de) Imidazolyl-substituierte Phenylessigsäureprolinamide
DE59404784D1 (de) Neue carbonsäureester von 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren herstellung sowie deren verwendung
EP0644768A4 (de) Verfahren und zusammensetzungen zur verhinderung von entzündungen, die durch endothelzellen und fibrinogen ausgelöst werden.
DE3670629D1 (de) Ester von cyclopropancarbonsaeure und 2,3-dihydro-4-phenyl-1h-inden-2-ol, ihre herstellung, ihre verwendung als parasitizide und sie enthaltende zusammensetzungen.
ATE175349T1 (de) Verwendung von etofibrat und pharmazeutische zusammensetzungen, enthaltend etofibrat, zur behandlung der diabetischen angio- und retinopathie
ATE96150T1 (de) Thioester und dessen verwendung zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von ischaemie und von reperfusionsyndromen.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties