ATE314844T1 - Verfahren und zusammensetzungen zur verabreichung von taxanen - Google Patents
Verfahren und zusammensetzungen zur verabreichung von taxanenInfo
- Publication number
- ATE314844T1 ATE314844T1 AT99909941T AT99909941T ATE314844T1 AT E314844 T1 ATE314844 T1 AT E314844T1 AT 99909941 T AT99909941 T AT 99909941T AT 99909941 T AT99909941 T AT 99909941T AT E314844 T1 ATE314844 T1 AT E314844T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- methods
- taxans
- administration
- taxol
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 2
- 229960001592 paclitaxel Drugs 0.000 abstract 2
- 229940123237 Taxane Drugs 0.000 abstract 1
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
- 125000002456 taxol group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7745998P | 1998-03-10 | 1998-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE314844T1 true ATE314844T1 (de) | 2006-02-15 |
Family
ID=22138176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99909941T ATE314844T1 (de) | 1998-03-10 | 1999-03-10 | Verfahren und zusammensetzungen zur verabreichung von taxanen |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20010029264A1 (de) |
| EP (1) | EP0977562B8 (de) |
| JP (1) | JP2001524988A (de) |
| KR (1) | KR20010012363A (de) |
| CN (1) | CN1255852A (de) |
| AT (1) | ATE314844T1 (de) |
| AU (1) | AU762926B2 (de) |
| BR (1) | BR9904856A (de) |
| CA (1) | CA2288240A1 (de) |
| CY (1) | CY1105690T1 (de) |
| DE (1) | DE69929313T2 (de) |
| DK (1) | DK0977562T3 (de) |
| ES (1) | ES2257038T3 (de) |
| IL (1) | IL131217A0 (de) |
| PT (1) | PT977562E (de) |
| WO (1) | WO1999045918A1 (de) |
| ZA (1) | ZA991885B (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| US6964946B1 (en) | 1995-10-26 | 2005-11-15 | Baker Norton Pharmaceuticals, Inc. | Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same |
| US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
| EP1479382A1 (de) * | 1999-06-18 | 2004-11-24 | IVAX Research, Inc. | Taxane enthaltende orale Pharmazeutische Zusammensetzungen sowie Behandlungsverfahren unter deren Verwendung |
| US6828346B2 (en) * | 1999-10-25 | 2004-12-07 | Supergen, Inc. | Methods for administration of paclitaxel |
| US6136846A (en) | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
| DE60111352T2 (de) * | 2000-01-20 | 2006-05-04 | Supratek Pharma, Inc., Montreal | Podophyllotoxin-zusammensetzungen |
| JP2003521545A (ja) * | 2000-02-02 | 2003-07-15 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | 改良された溶解性を有するタキサン製剤 |
| US6919370B2 (en) | 2000-11-28 | 2005-07-19 | Transform Pharmaceuticals, Inc. | Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof |
| CA2434641A1 (en) * | 2001-01-18 | 2002-08-22 | Pharmacia And Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| US7115565B2 (en) | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| AU2002351169B2 (en) * | 2001-11-26 | 2007-09-20 | Intas Pharmaceuticals Limited | Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions |
| AU2002357012A1 (en) * | 2001-11-27 | 2003-06-10 | Transform Pharmaceuticals, Inc. | Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof |
| CA2470826A1 (en) * | 2001-12-20 | 2003-07-03 | Bristol-Myers Squibb Company | Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability |
| EP1340497A1 (de) * | 2002-03-01 | 2003-09-03 | Novagali Sas | Selbstemulgierende Systeme zur Abgabe von schwerlöslichen Arzneimitteln |
| ES2283756T3 (es) * | 2002-03-01 | 2007-11-01 | Novagali Pharma Sa | Sistemas autoemulsionantes de administracion de farmaco para taxoides. |
| PT1553940E (pt) * | 2002-07-30 | 2008-05-09 | Wyeth Corp | Formulações parentéricas contendo um hidroxi-éster de rapamicina |
| DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
| WO2004050068A1 (en) | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
| US20040127551A1 (en) * | 2002-12-27 | 2004-07-01 | Kai Zhang | Taxane-based compositions and methods of use |
| ATE457716T1 (de) * | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| WO2004091506A2 (en) * | 2003-04-10 | 2004-10-28 | Ivax Research, Inc. | Taxane-based compositions and methods of use |
| EP1498120A1 (de) * | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Halbfeste Formulierung für die orale Verabreichung des Taxols |
| EP1510206A1 (de) * | 2003-08-29 | 2005-03-02 | Novagali Pharma SA | Selbstnanoemulgierende ölige Formulierung zur Verabreichung wasserschwerlöslicher Wirkstoffe |
| BRPI0418427A (pt) * | 2004-01-30 | 2007-06-12 | Pfizer Italia Srl | formulações farmacêuticas de matriz semi-sólida |
| WO2005074889A1 (en) * | 2004-02-03 | 2005-08-18 | Dinesh Shantilal Patel | Novel compositions of taxol derivatives and the process for the manufacture thereof |
| US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
| US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
| US7345093B2 (en) | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| US7659310B2 (en) | 2004-04-27 | 2010-02-09 | Formatech, Inc. | Methods of enhancing solubility of agents |
| WO2006039268A2 (en) * | 2004-09-30 | 2006-04-13 | Eastman Chemical Company | Pharmaceutical formulations containing vitamin e tpgs molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations |
| US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
| US20110038899A1 (en) * | 2008-03-28 | 2011-02-17 | Garry Thomas Gwozdz | Pharmaceutical Solutions and Method for Solublilizing Therapeutic Agents |
| US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
| CN102000052B (zh) * | 2008-06-25 | 2012-12-12 | 重庆市中药研究院 | 紫杉醇及其衍生物在制药中的应用 |
| US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
| CA2781529C (en) | 2009-09-23 | 2017-10-24 | Indu Javeri | Methods for the preparation of liposomes comprising docetaxel |
| US20120065255A1 (en) * | 2009-10-19 | 2012-03-15 | Nagesh Palepu | Cabazitaxel formulations and methods of preparing thereof |
| SG185389A1 (en) | 2010-05-03 | 2012-12-28 | Teikoku Pharma Usa Inc | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| MX2013007959A (es) * | 2011-01-10 | 2013-12-06 | Celgene Corp | Formas farmaceuticas orales de amida {2-[(1s)-1-(3-etoxi-4-metoxi- fenil]-2-metansulfonil-etil]-3-oxo-2,,3-dihidro-1h-isoindol -4-il}-del acido ciclopropancarboxilico. |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| EP3302423B1 (de) | 2015-06-04 | 2022-05-25 | Crititech, Inc. | Partikelproduktionssystem und partikelsammelvorrichtung |
| KR102742522B1 (ko) | 2015-09-16 | 2024-12-12 | 디에프비 소리아, 엘엘씨 | 약물 나노입자 전달체 및 이의 제조방법 |
| WO2017176628A1 (en) | 2016-04-04 | 2017-10-12 | Crititech, Inc. | Methods for solid tumor treatment |
| JP2020514359A (ja) | 2017-03-15 | 2020-05-21 | ディーエフビー ソリア リミテッド ライアビリティ カンパニー | タキサンのナノ粒子を用いる皮膚悪性腫瘍処置のための局所療法 |
| BR112019023948A2 (pt) | 2017-06-09 | 2020-06-09 | Crititech Inc | tratamento de cistos epiteliais por injeção intracística de partículas antineoplásicas |
| EP3615004B1 (de) | 2017-06-14 | 2025-02-19 | Crititech, Inc. | Verfahren zur behandlung von lungenerkrankungen |
| JP7792750B2 (ja) | 2017-10-03 | 2025-12-26 | クリティテック・インコーポレイテッド | 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達 |
| EP3765035A4 (de) | 2018-03-16 | 2021-10-27 | DFB Soria, LLC | Topische therapie zur behandlung von zervikalen intraepithelialen neoplasien (cin) und gebärmutterhalskrebs unter verwendung von taxannanopartikeln |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228162A (en) * | 1979-07-09 | 1980-10-14 | Research Corporation | Dimethyl isosorbide in liquid formulation of aspirin |
| US4578391A (en) * | 1982-01-20 | 1986-03-25 | Yamanouchi Pharmaceutical Co., Ltd. | Oily compositions of antitumor drugs |
| US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
| US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| CA2149150C (en) * | 1992-11-27 | 2000-08-01 | David R. Carver | Injectable taxol composition with improved stability |
| WO1995011039A1 (de) * | 1993-10-22 | 1995-04-27 | Hexal Pharma Gmbh | Pharmazeutische zusammensetzung mit cyclosporin a und alpha-tocopherol |
| US5877205A (en) * | 1996-06-28 | 1999-03-02 | Board Of Regents, The University Of Texas System | Parenteral paclitaxel in a stable non-toxic formulation |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
-
1998
- 1998-03-10 IL IL13121798A patent/IL131217A0/xx unknown
-
1999
- 1999-03-09 ZA ZA9901885A patent/ZA991885B/xx unknown
- 1999-03-10 EP EP99909941A patent/EP0977562B8/de not_active Expired - Lifetime
- 1999-03-10 DK DK99909941T patent/DK0977562T3/da active
- 1999-03-10 KR KR19997010315A patent/KR20010012363A/ko not_active Withdrawn
- 1999-03-10 BR BR9904856-6A patent/BR9904856A/pt not_active Application Discontinuation
- 1999-03-10 DE DE69929313T patent/DE69929313T2/de not_active Expired - Fee Related
- 1999-03-10 CN CN99800022A patent/CN1255852A/zh active Pending
- 1999-03-10 ES ES99909941T patent/ES2257038T3/es not_active Expired - Lifetime
- 1999-03-10 AU AU29022/99A patent/AU762926B2/en not_active Ceased
- 1999-03-10 AT AT99909941T patent/ATE314844T1/de not_active IP Right Cessation
- 1999-03-10 JP JP54602599A patent/JP2001524988A/ja not_active Ceased
- 1999-03-10 CA CA002288240A patent/CA2288240A1/en not_active Abandoned
- 1999-03-10 PT PT99909941T patent/PT977562E/pt unknown
- 1999-03-10 WO PCT/US1999/005151 patent/WO1999045918A1/en not_active Ceased
-
2001
- 2001-02-28 US US09/795,626 patent/US20010029264A1/en not_active Abandoned
-
2006
- 2006-03-29 CY CY20061100438T patent/CY1105690T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL131217A0 (en) | 2001-01-28 |
| ZA991885B (en) | 1999-09-10 |
| CY1105690T1 (el) | 2010-12-22 |
| KR20010012363A (ko) | 2001-02-15 |
| AU762926B2 (en) | 2003-07-10 |
| MX9910340A (en) | 2000-04-01 |
| EP0977562B1 (de) | 2006-01-04 |
| AU2902299A (en) | 1999-09-27 |
| CA2288240A1 (en) | 1999-09-16 |
| DE69929313D1 (de) | 2006-03-30 |
| BR9904856A (pt) | 2000-07-18 |
| PT977562E (pt) | 2006-05-31 |
| CN1255852A (zh) | 2000-06-07 |
| EP0977562A1 (de) | 2000-02-09 |
| ES2257038T3 (es) | 2006-07-16 |
| EP0977562B8 (de) | 2006-04-26 |
| WO1999045918A1 (en) | 1999-09-16 |
| DE69929313T2 (de) | 2006-08-17 |
| JP2001524988A (ja) | 2001-12-04 |
| US20010029264A1 (en) | 2001-10-11 |
| DK0977562T3 (da) | 2006-05-01 |
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