ATE315230T1 - Verfahren zum identifizieren von prostaglandin d2 rezeptor modulatoren - Google Patents

Verfahren zum identifizieren von prostaglandin d2 rezeptor modulatoren

Info

Publication number
ATE315230T1
ATE315230T1 AT00953560T AT00953560T ATE315230T1 AT E315230 T1 ATE315230 T1 AT E315230T1 AT 00953560 T AT00953560 T AT 00953560T AT 00953560 T AT00953560 T AT 00953560T AT E315230 T1 ATE315230 T1 AT E315230T1
Authority
AT
Austria
Prior art keywords
identifying
prostaglandin
receptor
receptor modulators
test substance
Prior art date
Application number
AT00953560T
Other languages
English (en)
Inventor
Hiroyuki Hirai
Kazuyuki Ogawa
Kinya Nagata
Syoichi Takano
Original Assignee
Bml Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bml Inc filed Critical Bml Inc
Application granted granted Critical
Publication of ATE315230T1 publication Critical patent/ATE315230T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT00953560T 1999-08-23 2000-08-22 Verfahren zum identifizieren von prostaglandin d2 rezeptor modulatoren ATE315230T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23620799 1999-08-23
JP2000153172 2000-05-24

Publications (1)

Publication Number Publication Date
ATE315230T1 true ATE315230T1 (de) 2006-02-15

Family

ID=26532542

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00953560T ATE315230T1 (de) 1999-08-23 2000-08-22 Verfahren zum identifizieren von prostaglandin d2 rezeptor modulatoren

Country Status (9)

Country Link
US (1) US6884593B1 (de)
EP (1) EP1211513B1 (de)
JP (1) JP3486408B2 (de)
AT (1) ATE315230T1 (de)
AU (1) AU772121B2 (de)
CA (1) CA2383135C (de)
DE (2) DE1211513T1 (de)
NO (1) NO20020837L (de)
WO (1) WO2001014882A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878522B2 (en) * 2000-07-07 2005-04-12 Baiyong Li Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2
JP2005508164A (ja) * 2001-10-10 2005-03-31 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ２１１３２、ヒトｇタンパク質共役レセプターファミリーメンバーおよびそれらの使用
EP2423190A1 (de) * 2002-05-16 2012-02-29 Shionogi&Co., Ltd. PGD-2-Rezetorantagonismus aufweisende Verbindungen
WO2003097042A1 (en) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Pgd2 receptor antagonist
ES2401079T3 (es) 2002-12-20 2013-04-16 Amgen Inc. Moduladores del asma y de la inflamación alérgica
SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
JP4051398B2 (ja) 2004-03-11 2008-02-20 アクテリオン ファマシューティカルズ リミテッド テトラヒドロピリドインドール誘導体
WO2005102338A1 (en) * 2004-04-20 2005-11-03 Pfizer Limited Method of treating neuropathic pain using a crth2 receptor antagonist
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
EP1817282B1 (de) 2004-11-23 2011-07-20 AstraZeneca AB Zur behandlung von atemwegserkrankungen geeignete phenoxyessigsäurederivate
EP1937632A1 (de) * 2005-10-06 2008-07-02 Astra Zeneca AB Neue verbindungen
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
ES2391671T3 (es) 2006-07-22 2012-11-28 Oxagen Limited Compuestos con actividad antagonista de CRTH2
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
US20100280049A1 (en) * 2007-11-06 2010-11-04 Amira Pharmaceuticals, Inc. Antagonists of pgd2 receptors
WO2009061681A2 (en) * 2007-11-06 2009-05-14 Amira Pharmaceuticals, Inc Antagonists of pgd2 receptors
ES2471919T3 (es) 2007-12-19 2014-06-27 Amgen, Inc Derivados de ácido fenilac�tico como moduladores de inflamación
DK2250161T3 (da) 2008-01-18 2014-01-27 Atopix Therapeutics Ltd Forbindelser med CRTH2-antagonistaktivitet
EP2240444A1 (de) 2008-01-22 2010-10-20 Oxagen Limited Verbindungen mit crth2-antagonistischer wirkung
EP2245002A4 (de) * 2008-02-01 2011-08-17 Amira Pharmaceuticals Inc N,n-disubstituierte aminoalkylbiphenyl-antagonisten von prostaglandin d2-rezeptoren
US8067445B2 (en) * 2008-02-01 2011-11-29 Panmira Pharmaceuticals, Llc N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors
EP2257536A4 (de) * 2008-02-14 2011-03-23 Amira Pharmaceuticals Inc Cyclische diarylether als antagonisten von prostaglandin-d2-rezeptoren
US8497381B2 (en) * 2008-02-25 2013-07-30 Panmira Pharmaceuticals, Llc Antagonists of prostaglandin D2 receptors
US8426449B2 (en) * 2008-04-02 2013-04-23 Panmira Pharmaceuticals, Llc Aminoalkylphenyl antagonists of prostaglandin D2 receptors
MX2010014172A (es) 2008-07-03 2011-02-22 Amira Pharmaceuticals Inc Antagonistas de receptores de prostaglandina d2.
GB2463788B (en) * 2008-09-29 2010-12-15 Amira Pharmaceuticals Inc Heteroaryl antagonists of prostaglandin D2 receptors
WO2010039977A2 (en) 2008-10-01 2010-04-08 Amira Pharmaceuticals, Inc. Heteroaryl antagonists of prostaglandin d2 receptors
US8524748B2 (en) 2008-10-08 2013-09-03 Panmira Pharmaceuticals, Llc Heteroalkyl biphenyl antagonists of prostaglandin D2 receptors
US8383654B2 (en) 2008-11-17 2013-02-26 Panmira Pharmaceuticals, Llc Heterocyclic antagonists of prostaglandin D2 receptors
US20100173313A1 (en) * 2009-01-08 2010-07-08 Amira Pharmaceuticals, Inc. Biomarkers of inflammation
WO2011014587A2 (en) 2009-07-31 2011-02-03 Amira Pharmaceuticals, Inc. Ophthalmic pharmaceutical compositions of dp2 receptor antagonists
KR20120047273A (ko) * 2009-08-05 2012-05-11 판미라 파마슈티칼스, 엘엘씨 Ｄｐ2 길항제 및 이의 용도
MX2012007927A (es) 2010-01-06 2012-08-15 Panmira Pharmaceuticals Llc Antagonistas de dp2 y usos del mismo.
GB201103837D0 (en) 2011-03-07 2011-04-20 Oxagen Ltd Amorphous (5-Fluoro-2-Methyl-3-Quinolin-2-Ylmethyl-Indol-1-Yl)-acetic acid
EP2912458B1 (de) 2012-10-24 2018-07-18 NYU Winthrop Hospital Nichtinvasiver biomarker zur identifizierung von patientinnen mit erhöhtem risiko für eine frühgeburt
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
KR20200109293A (ko) 2017-09-13 2020-09-22 프로제너티, 인크. 자간전증 바이오마커 및 관련된 시스템 및 방법
WO2021113710A1 (en) 2019-12-04 2021-06-10 Progenity, Inc. Assessment of preeclampsia using assays for free and dissociated placental growth factor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69734141T2 (de) * 1996-06-05 2006-07-13 Bml Inc. PROTEIN, DAS FÜR MENSCHLICHE Th2-ZELLEN SPEZIFISCH IST, DAFÜR KODIERENDES GEN UND KORRESPONDIERENDE TRANSFORMANTE, REKOMBINANTER VEKTOR UND MONOKLONALER ANTKÖRPER
US6878522B2 (en) 2000-07-07 2005-04-12 Baiyong Li Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2

Also Published As

Publication number Publication date
EP1211513A4 (de) 2003-04-16
NO20020837L (no) 2002-04-22
DE60025368T2 (de) 2006-09-14
CA2383135A1 (en) 2001-03-01
US6884593B1 (en) 2005-04-26
NO20020837D0 (no) 2002-02-20
AU772121B2 (en) 2004-04-08
DE1211513T1 (de) 2002-11-14
DE60025368D1 (de) 2006-03-30
CA2383135C (en) 2010-11-30
WO2001014882A1 (fr) 2001-03-01
JP3486408B2 (ja) 2004-01-13
EP1211513A1 (de) 2002-06-05
AU6598800A (en) 2001-03-19
EP1211513B1 (de) 2006-01-04

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