ATE315405T1 - Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung - Google Patents
Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendungInfo
- Publication number
- ATE315405T1 ATE315405T1 AT99939711T AT99939711T ATE315405T1 AT E315405 T1 ATE315405 T1 AT E315405T1 AT 99939711 T AT99939711 T AT 99939711T AT 99939711 T AT99939711 T AT 99939711T AT E315405 T1 ATE315405 T1 AT E315405T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- methods
- saponin adjuvants
- cpg
- immunostimulatory oligonucleotides
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9591398P | 1998-08-10 | 1998-08-10 | |
| US12860899P | 1999-04-08 | 1999-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE315405T1 true ATE315405T1 (de) | 2006-02-15 |
Family
ID=26790746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99939711T ATE315405T1 (de) | 1998-08-10 | 1999-08-06 | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7049302B1 (de) |
| EP (1) | EP1104306B1 (de) |
| JP (1) | JP4620251B2 (de) |
| AT (1) | ATE315405T1 (de) |
| AU (1) | AU773204C (de) |
| CA (1) | CA2340174C (de) |
| DE (1) | DE69929444T2 (de) |
| DK (1) | DK1104306T3 (de) |
| ES (1) | ES2257068T3 (de) |
| PT (1) | PT1104306E (de) |
| WO (1) | WO2000009159A1 (de) |
Families Citing this family (95)
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|---|---|---|---|---|
| US20030026782A1 (en) | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| US6589940B1 (en) | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| US20020147143A1 (en) | 1998-03-18 | 2002-10-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| DK1077722T3 (da) | 1998-05-22 | 2006-11-27 | Ottawa Health Research Inst | Fremgangsmåder og produkter til induktion af mukosaimmunitet |
| ATE315405T1 (de) * | 1998-08-10 | 2006-02-15 | Antigenics Inc | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| DE60044236D1 (de) * | 1999-02-17 | 2010-06-02 | Csl Ltd | Immunogene komplexe und methoden in bezug auf diese |
| US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| GB9908885D0 (en) * | 1999-04-19 | 1999-06-16 | Smithkline Beecham Biolog | Vccine |
| DK1187629T3 (da) * | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| DE60039715D1 (de) * | 1999-11-19 | 2008-09-11 | Csl Ltd | Hcv-impfstoff zusammensetzungen |
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| SI1650221T1 (sl) | 2000-02-23 | 2012-09-28 | Glaxosmithkline Biolog Sa | Nove spojine |
| PT2133100E (pt) | 2000-06-20 | 2012-01-11 | Corixa Corp | Antigénio mtb32a de mycobacterium tuberculosis com um local activo inactivado e suas proteínas de fusão |
| EP1319069B1 (de) | 2000-06-28 | 2008-05-21 | Corixa Corporation | Zusammensetzungen und verfahren für therapie und diagnose von lungenkrebs |
| UA79735C2 (uk) | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
| ATE534401T1 (de) * | 2000-10-18 | 2011-12-15 | Glaxosmithkline Biolog Sa | Mage antigen gekoppelt an einem protein d fragment enthaltende impfstoffe |
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| CA2446788A1 (en) | 2001-05-09 | 2002-11-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
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| EP1581119B1 (de) | 2001-12-17 | 2013-01-30 | Corixa Corporation | Zusammensetzungen und verfahren zur behandlung und diagnose von entzündlicher darmerkrankung |
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| ATE489969T1 (de) * | 2002-06-20 | 2010-12-15 | Cytos Biotechnology Ag | Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung |
| CN100421730C (zh) * | 2002-07-10 | 2008-10-01 | 英特威国际有限公司 | 免疫原性组合物 |
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| US6013258A (en) * | 1997-10-09 | 2000-01-11 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
| US6218371B1 (en) * | 1998-04-03 | 2001-04-17 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| AU760795B2 (en) | 1998-05-14 | 2003-05-22 | Coley Pharmaceutical Gmbh | Methods for regulating hematopoiesis using CpG-oligonucleotides |
| DK1077722T3 (da) * | 1998-05-22 | 2006-11-27 | Ottawa Health Research Inst | Fremgangsmåder og produkter til induktion af mukosaimmunitet |
| US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| ATE315405T1 (de) * | 1998-08-10 | 2006-02-15 | Antigenics Inc | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| US20010034330A1 (en) | 1998-08-10 | 2001-10-25 | Charlotte Kensil | Innate immunity-stimulating compositions of CpG and saponin and methods thereof |
| CA2344558A1 (en) | 1998-10-09 | 2000-04-20 | Dynavax Technologies Corporation | Anti hiv compositions comprising immunostimulatory polynucleotides and hiv antigens |
| DK1187629T3 (da) | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| US6558670B1 (en) | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
| IL155282A0 (en) | 2000-10-18 | 2003-11-23 | Glaxosmithkline Biolog Sa | Vaccines |
| US20030119774A1 (en) * | 2001-09-25 | 2003-06-26 | Marianna Foldvari | Compositions and methods for stimulating an immune response |
| AR045702A1 (es) * | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| KR20050048539A (ko) * | 2001-10-06 | 2005-05-24 | 메리얼엘엘씨 | CpG 제제 및 관련된 방법 |
| SE0301998D0 (sv) * | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| GB0401239D0 (en) * | 2004-01-21 | 2004-02-25 | Molecularnature Ltd | Adjuvant compositions |
-
1999
- 1999-08-06 AT AT99939711T patent/ATE315405T1/de active
- 1999-08-06 DK DK99939711T patent/DK1104306T3/da active
- 1999-08-06 JP JP2000564661A patent/JP4620251B2/ja not_active Expired - Lifetime
- 1999-08-06 AU AU53953/99A patent/AU773204C/en not_active Expired
- 1999-08-06 PT PT99939711T patent/PT1104306E/pt unknown
- 1999-08-06 EP EP99939711A patent/EP1104306B1/de not_active Expired - Lifetime
- 1999-08-06 ES ES99939711T patent/ES2257068T3/es not_active Expired - Lifetime
- 1999-08-06 CA CA2340174A patent/CA2340174C/en not_active Expired - Lifetime
- 1999-08-06 US US09/369,941 patent/US7049302B1/en not_active Expired - Lifetime
- 1999-08-06 DE DE69929444T patent/DE69929444T2/de not_active Expired - Lifetime
- 1999-08-06 WO PCT/US1999/017956 patent/WO2000009159A1/en not_active Ceased
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2006
- 2006-03-10 US US11/373,806 patent/US7858589B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU773204B2 (en) | 2004-05-20 |
| JP2002522510A (ja) | 2002-07-23 |
| WO2000009159A9 (en) | 2000-07-27 |
| DE69929444D1 (de) | 2006-04-06 |
| EP1104306A1 (de) | 2001-06-06 |
| AU5395399A (en) | 2000-03-06 |
| US20060177458A1 (en) | 2006-08-10 |
| CA2340174A1 (en) | 2000-02-24 |
| DE69929444T2 (de) | 2006-09-28 |
| US7858589B2 (en) | 2010-12-28 |
| US7049302B1 (en) | 2006-05-23 |
| WO2000009159A1 (en) | 2000-02-24 |
| EP1104306B1 (de) | 2006-01-11 |
| CA2340174C (en) | 2011-01-04 |
| ES2257068T3 (es) | 2006-07-16 |
| DK1104306T3 (da) | 2006-05-22 |
| AU773204C (en) | 2005-05-19 |
| JP4620251B2 (ja) | 2011-01-26 |
| PT1104306E (pt) | 2006-05-31 |
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