ATE315575T1 - Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung - Google Patents

Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung

Info

Publication number: ATE315575T1
Authority: AT; Austria
Prior art keywords: immunopotentizing; inosine monophosphate; monophosphate derivatives; nucleotidase; monophosphate
Prior art date: 1995-04-21

Application number

AT95918836T

Other languages

English (en)

Inventor

John W Hadden

Alfredo Giner-Sorolla

K Noel Masihi

Original Assignee

Univ South Florida

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-21

Filing date

1995-04-21

Publication date

2006-02-15

1995-04-21 Application filed by Univ South Florida filed Critical Univ South Florida

1995-04-21 Priority claimed from EP95918836A external-priority patent/EP0821692B1/de

2006-02-15 Application granted granted Critical

2006-02-15 Publication of ATE315575T1 publication Critical patent/ATE315575T1/de

Links

GRSZFWQUAKGDAV-KQYNXXCUSA-N IMP Chemical class O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-KQYNXXCUSA-N 0.000 title abstract 4
102000004008 5'-Nucleotidase Human genes 0.000 title abstract 2
108010043671 prostatic acid phosphatase Proteins 0.000 title abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000717 retained effect Effects 0.000 abstract 1
125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Mycology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT95918836T 1995-04-21 1995-04-21 Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung ATE315575T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP95918836A EP0821692B1 (de)	1995-04-21	1995-04-21	Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung

Publications (1)

Publication Number	Publication Date
ATE315575T1 true ATE315575T1 (de)	2006-02-15

Family

ID=32799251

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95918836T ATE315575T1 (de)	1995-04-21	1995-04-21	Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung

Country Status (2)

Country	Link
EP (1)	EP1459760A1 (de)
AT (1)	ATE315575T1 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1206513B (it) *	1983-08-04	1989-04-27	Btb Ind Chimica	Composizioni farmaceutiche adattivita'antibiotica-immunostimolante.
EP0821692B1 (de)	1995-04-21	2006-01-11	University Of South Florida	Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung

1995
- 1995-04-21 EP EP20040002425 patent/EP1459760A1/de not_active Withdrawn
- 1995-04-21 AT AT95918836T patent/ATE315575T1/de active

Also Published As

Publication number	Publication date
EP1459760A1 (de)	2004-09-22
EP1459760A9 (de)	2005-01-12

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2006-11-15

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