ATE316137T1 - Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor - Google Patents

Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor

Info

Publication number
ATE316137T1
ATE316137T1 AT01931876T AT01931876T ATE316137T1 AT E316137 T1 ATE316137 T1 AT E316137T1 AT 01931876 T AT01931876 T AT 01931876T AT 01931876 T AT01931876 T AT 01931876T AT E316137 T1 ATE316137 T1 AT E316137T1
Authority
AT
Austria
Prior art keywords
growth factor
antibodies against
factor receptor
epidermal growth
humanized antibodies
Prior art date
Application number
AT01931876T
Other languages
English (en)
Inventor
John Robert Maxwell Ellis
Linda Gillian Durrant
Original Assignee
Scancell Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0011981A external-priority patent/GB0011981D0/en
Priority claimed from GB0020794A external-priority patent/GB0020794D0/en
Application filed by Scancell Ltd filed Critical Scancell Ltd
Application granted granted Critical
Publication of ATE316137T1 publication Critical patent/ATE316137T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/467—Igs with modifications in the FR-residues only
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01931876T 2000-05-19 2001-05-21 Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor ATE316137T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0011981A GB0011981D0 (en) 2000-05-19 2000-05-19 Complementary determining regions of antibodies that show amino acid homology with peptide ligand
GB0020794A GB0020794D0 (en) 2000-08-24 2000-08-24 Humanised antibodies

Publications (1)

Publication Number Publication Date
ATE316137T1 true ATE316137T1 (de) 2006-02-15

Family

ID=26244299

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01931876T ATE316137T1 (de) 2000-05-19 2001-05-21 Humanisierte antikörper gegen den epidermalen wachstumsfaktorrezeptor

Country Status (12)

Country Link
US (3) US20040091485A1 (de)
EP (1) EP1278851B1 (de)
JP (1) JP2003533987A (de)
KR (1) KR100480985B1 (de)
CN (1) CN1239701C (de)
AT (1) ATE316137T1 (de)
AU (1) AU2001258567A1 (de)
BR (1) BR0110927A (de)
CA (1) CA2409361A1 (de)
DE (1) DE60116753T2 (de)
ES (1) ES2259030T3 (de)
WO (1) WO2001088138A1 (de)

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CN1239701C (zh) 2006-02-01
KR100480985B1 (ko) 2005-04-07
KR20030021161A (ko) 2003-03-12
JP2003533987A (ja) 2003-11-18
ES2259030T3 (es) 2006-09-16
US20080260735A1 (en) 2008-10-23
CA2409361A1 (en) 2001-11-22
WO2001088138A1 (en) 2001-11-22
CN1432063A (zh) 2003-07-23
AU2001258567A1 (en) 2001-11-26
DE60116753D1 (de) 2006-04-06
US20040091485A1 (en) 2004-05-13
EP1278851A1 (de) 2003-01-29
DE60116753T2 (de) 2006-09-14
BR0110927A (pt) 2003-03-11
US20060240003A1 (en) 2006-10-26

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