ATE316972T1 - Trizyklische crf rezeptor antagonisten - Google Patents
Trizyklische crf rezeptor antagonistenInfo
- Publication number
- ATE316972T1 ATE316972T1 AT02752340T AT02752340T ATE316972T1 AT E316972 T1 ATE316972 T1 AT E316972T1 AT 02752340 T AT02752340 T AT 02752340T AT 02752340 T AT02752340 T AT 02752340T AT E316972 T1 ATE316972 T1 AT E316972T1
- Authority
- AT
- Austria
- Prior art keywords
- tricyclic
- receptor antagonists
- crf receptor
- formula
- crf
- Prior art date
Links
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 102000012289 Corticotropin-Releasing Hormone Human genes 0.000 abstract 2
- 108010022152 Corticotropin-Releasing Hormone Proteins 0.000 abstract 2
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- External Artificial Organs (AREA)
- Mechanical Coupling Of Light Guides (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0117395.4A GB0117395D0 (en) | 2001-07-17 | 2001-07-17 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE316972T1 true ATE316972T1 (de) | 2006-02-15 |
Family
ID=9918654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02752340T ATE316972T1 (de) | 2001-07-17 | 2002-07-15 | Trizyklische crf rezeptor antagonisten |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1425281B1 (de) |
| JP (1) | JP2004537555A (de) |
| KR (1) | KR20040027880A (de) |
| CN (1) | CN1541217A (de) |
| AT (1) | ATE316972T1 (de) |
| AU (1) | AU2002354916B2 (de) |
| BR (1) | BR0211220A (de) |
| CA (1) | CA2452009A1 (de) |
| DE (1) | DE60209014T2 (de) |
| ES (1) | ES2256506T3 (de) |
| GB (1) | GB0117395D0 (de) |
| HU (1) | HUP0400460A2 (de) |
| IL (1) | IL159521A0 (de) |
| MX (1) | MXPA04000492A (de) |
| NO (1) | NO20040203L (de) |
| NZ (1) | NZ530508A (de) |
| PL (1) | PL367965A1 (de) |
| RU (1) | RU2004104464A (de) |
| WO (1) | WO2003008414A1 (de) |
| ZA (1) | ZA200309942B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0209035A (pt) | 2001-04-30 | 2004-08-10 | Glaxo Group Ltd | Antagonistas de receptor crf |
| CZ20033165A3 (cs) | 2001-05-21 | 2004-10-13 | Neurocrineáinc | Tri@ a tetraazaacenaftylenové deriváty jako antagonisté receptoru CRF |
| EP2002836B1 (de) * | 2007-05-31 | 2010-10-20 | Nerviano Medical Sciences S.r.l. | Zyklokondensierte Azaindole, die als Kinase-Hemmer wirken |
| JP5719840B2 (ja) | 2009-06-08 | 2015-05-20 | 武田薬品工業株式会社 | Ｊａｋの阻害剤としてのジヒドロピロロナフチリジノン化合物 |
| RU2498986C2 (ru) * | 2011-07-20 | 2013-11-20 | Учреждение Российской Академии Наук Институт Проблем Химической Физики Ран (Ипхф Ран) | ТЕТРАЦИАНОЗАМЕЩЕННЫЕ 1,4,9b-ТРИАЗАФЕНАЛЕНЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ |
| CN106279011A (zh) * | 2016-08-16 | 2017-01-04 | 成都百事兴科技实业有限公司 | 一种2,4‑二羟基‑6‑甲基烟酸乙酯的制备方法 |
| KR102462991B1 (ko) * | 2020-11-02 | 2022-11-04 | 한국해양과학기술원 | 남극-유래 진균 균주 아크레모늄(Acremonium sp.) SF-7394에서 분리한 화합물 및 이를 포함하는 항염증, 항암 또는 항당뇨용 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4605642A (en) * | 1984-02-23 | 1986-08-12 | The Salk Institute For Biological Studies | CRF antagonists |
| WO2000027850A2 (en) * | 1998-11-12 | 2000-05-18 | Neurocrine Biosciences, Inc. | Crf receptor antagonists and methods relating thereto |
| US6514982B1 (en) * | 1998-11-12 | 2003-02-04 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
-
2001
- 2001-07-17 GB GBGB0117395.4A patent/GB0117395D0/en not_active Ceased
-
2002
- 2002-07-15 PL PL02367965A patent/PL367965A1/xx not_active Application Discontinuation
- 2002-07-15 HU HU0400460A patent/HUP0400460A2/hu unknown
- 2002-07-15 CA CA002452009A patent/CA2452009A1/en not_active Abandoned
- 2002-07-15 EP EP02752340A patent/EP1425281B1/de not_active Expired - Lifetime
- 2002-07-15 RU RU2004104464/04A patent/RU2004104464A/ru not_active Application Discontinuation
- 2002-07-15 IL IL15952102A patent/IL159521A0/xx unknown
- 2002-07-15 DE DE60209014T patent/DE60209014T2/de not_active Expired - Fee Related
- 2002-07-15 MX MXPA04000492A patent/MXPA04000492A/es active IP Right Grant
- 2002-07-15 KR KR10-2004-7000714A patent/KR20040027880A/ko not_active Withdrawn
- 2002-07-15 AU AU2002354916A patent/AU2002354916B2/en not_active Ceased
- 2002-07-15 JP JP2003513973A patent/JP2004537555A/ja active Pending
- 2002-07-15 NZ NZ530508A patent/NZ530508A/en unknown
- 2002-07-15 BR BR0211220-5A patent/BR0211220A/pt not_active IP Right Cessation
- 2002-07-15 WO PCT/US2002/022394 patent/WO2003008414A1/en not_active Ceased
- 2002-07-15 ES ES02752340T patent/ES2256506T3/es not_active Expired - Lifetime
- 2002-07-15 CN CNA02815746XA patent/CN1541217A/zh active Pending
- 2002-07-15 AT AT02752340T patent/ATE316972T1/de not_active IP Right Cessation
-
2003
- 2003-12-23 ZA ZA200309942A patent/ZA200309942B/xx unknown
-
2004
- 2004-01-16 NO NO20040203A patent/NO20040203L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60209014D1 (de) | 2006-04-13 |
| ES2256506T3 (es) | 2006-07-16 |
| MXPA04000492A (es) | 2005-03-07 |
| EP1425281B1 (de) | 2006-02-01 |
| WO2003008414A1 (en) | 2003-01-30 |
| DE60209014T2 (de) | 2006-07-13 |
| KR20040027880A (ko) | 2004-04-01 |
| BR0211220A (pt) | 2004-07-13 |
| NO20040203L (no) | 2004-03-16 |
| CA2452009A1 (en) | 2003-01-30 |
| ZA200309942B (en) | 2004-05-25 |
| PL367965A1 (en) | 2005-03-07 |
| EP1425281A1 (de) | 2004-06-09 |
| IL159521A0 (en) | 2004-06-01 |
| GB0117395D0 (en) | 2001-09-05 |
| CN1541217A (zh) | 2004-10-27 |
| HUP0400460A2 (hu) | 2005-01-28 |
| AU2002354916B2 (en) | 2006-10-19 |
| JP2004537555A (ja) | 2004-12-16 |
| NZ530508A (en) | 2005-11-25 |
| RU2004104464A (ru) | 2005-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |