ATE317703T1 - Polymer-wirkstoff-konjugate zur behandlung von krebs - Google Patents
Polymer-wirkstoff-konjugate zur behandlung von krebsInfo
- Publication number
- ATE317703T1 ATE317703T1 AT98928427T AT98928427T ATE317703T1 AT E317703 T1 ATE317703 T1 AT E317703T1 AT 98928427 T AT98928427 T AT 98928427T AT 98928427 T AT98928427 T AT 98928427T AT E317703 T1 ATE317703 T1 AT E317703T1
- Authority
- AT
- Austria
- Prior art keywords
- polymer
- cancer
- treatment
- drug
- active conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9712100.8A GB9712100D0 (en) | 1997-06-12 | 1997-06-12 | Biologically active materials |
| US5427797P | 1997-07-30 | 1997-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE317703T1 true ATE317703T1 (de) | 2006-03-15 |
Family
ID=26311695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98928427T ATE317703T1 (de) | 1997-06-12 | 1998-06-12 | Polymer-wirkstoff-konjugate zur behandlung von krebs |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6338843B1 (de) |
| EP (1) | EP0998303B1 (de) |
| JP (1) | JP2002508758A (de) |
| AT (1) | ATE317703T1 (de) |
| AU (1) | AU8025998A (de) |
| DE (1) | DE69833487T9 (de) |
| WO (1) | WO1998056424A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1619210A1 (de) * | 1998-10-30 | 2006-01-25 | Daiichi Pharmaceutical Co., Ltd. | DDS-Verbindungen und Methoden ihrer Prüfung |
| US6818630B1 (en) | 1999-06-18 | 2004-11-16 | Ml Laboratories Plc | Biologically active materials |
| WO2002002146A2 (en) * | 2000-07-01 | 2002-01-10 | Ml Laboratories Plc | Dextrin-amphotericin conjugates and their methods of preparation |
| DE60131177T2 (de) * | 2000-09-06 | 2008-08-07 | AP Pharma, Inc., Redwood | Abbaubare polyacetal-polymere |
| DE10112825A1 (de) | 2001-03-16 | 2002-10-02 | Fresenius Kabi De Gmbh | HESylierung von Wirkstoffen in wässriger Lösung |
| DE10129369C1 (de) * | 2001-06-21 | 2003-03-06 | Fresenius Kabi De Gmbh | Wasserlösliches, einen Aminozucker aufweisendes Antibiotikum in Form eines Pol ysaccharid-Konjugats |
| DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| ITMI20020681A1 (it) * | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Procedimento per la produzione di nanoparticelle di paclitaxel ed albumina |
| ATE409048T1 (de) * | 2002-10-08 | 2008-10-15 | Fresenius Kabi De Gmbh | Pharmazeutisch aktive oligosaccharid-conjugate |
| US6906158B2 (en) | 2003-03-13 | 2005-06-14 | Irm, Llc | Compositions and methods of vinyl oxazolone polymerization |
| WO2005014655A2 (en) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
| JP2007529554A (ja) * | 2004-03-19 | 2007-10-25 | プロ−ファーマシューティカルズ，インク． | 多価リガンド結合糖質ポリマーを用いた組成物、および該組成物による転移腫瘍の標的療法 |
| US11331392B2 (en) | 2014-12-04 | 2022-05-17 | The Trustees Of Columbia University In The City Of New York | Biodegradable thermo-responsive polymers and uses thereof |
| GB2551979A (en) | 2016-06-30 | 2018-01-10 | Rs Arastirma Egitim Danismanlik Llac Sanayi Ticaret Ltd | Cleavable polymer drug conjugates |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1044798B (it) * | 1974-10-15 | 1980-04-21 | Ferruti Paolo | Alti polimeri contenenti acido nicotinico processo per la loro preparazione e loro impiego |
| JPS5756500A (en) * | 1980-09-22 | 1982-04-05 | Otsuka Pharmaceut Co Ltd | Novel bufadienolide-type steroid |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US5554386A (en) * | 1986-07-03 | 1996-09-10 | Advanced Magnetics, Inc. | Delivery of therapeutic agents to receptors using polysaccharides |
| US4793986A (en) * | 1987-02-25 | 1988-12-27 | Johnson Matthey, Inc. | Macromolecular platinum antitumor compounds |
| GB9020861D0 (en) * | 1990-09-25 | 1990-11-07 | Ml Lab Plc | Pharmaceutical compositions |
| EP0540751A4 (en) * | 1991-05-20 | 1994-10-26 | Eisai Co Ltd | Steroid compound combined with polysaccharide |
| GB9217998D0 (en) * | 1992-08-24 | 1992-10-07 | Wellcome Found | Methods of treating cancer |
| WO1995005199A1 (en) * | 1993-08-19 | 1995-02-23 | Dextran Products Limited | Pharmaceutical preparation and a process for making same |
-
1998
- 1998-06-12 DE DE69833487T patent/DE69833487T9/de not_active Expired - Fee Related
- 1998-06-12 AT AT98928427T patent/ATE317703T1/de not_active IP Right Cessation
- 1998-06-12 US US09/445,793 patent/US6338843B1/en not_active Expired - Fee Related
- 1998-06-12 AU AU80259/98A patent/AU8025998A/en not_active Abandoned
- 1998-06-12 JP JP50182699A patent/JP2002508758A/ja not_active Ceased
- 1998-06-12 EP EP98928427A patent/EP0998303B1/de not_active Expired - Lifetime
- 1998-06-12 WO PCT/GB1998/001567 patent/WO1998056424A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998056424A1 (en) | 1998-12-17 |
| EP0998303B1 (de) | 2006-02-15 |
| US6338843B1 (en) | 2002-01-15 |
| DE69833487T2 (de) | 2006-10-12 |
| JP2002508758A (ja) | 2002-03-19 |
| DE69833487T9 (de) | 2007-03-01 |
| EP0998303A1 (de) | 2000-05-10 |
| AU8025998A (en) | 1998-12-30 |
| DE69833487D1 (de) | 2006-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |