ATE318307T1 - Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen. - Google Patents

Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen.

Info

Publication number
ATE318307T1
ATE318307T1 AT97915189T AT97915189T ATE318307T1 AT E318307 T1 ATE318307 T1 AT E318307T1 AT 97915189 T AT97915189 T AT 97915189T AT 97915189 T AT97915189 T AT 97915189T AT E318307 T1 ATE318307 T1 AT E318307T1
Authority
AT
Austria
Prior art keywords
embryos
cells
ungarden
culture
cell
Prior art date
Application number
AT97915189T
Other languages
English (en)
Inventor
Steven L Stice
Paul J Golueke
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24508762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE318307(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Application granted granted Critical
Publication of ATE318307T1 publication Critical patent/ATE318307T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT97915189T 1996-04-01 1997-03-24 Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen. ATE318307T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/626,054 US5905042A (en) 1996-04-01 1996-04-01 Cultured inner cell mass cell lines derived from bovine or porcine embryos

Publications (1)

Publication Number Publication Date
ATE318307T1 true ATE318307T1 (de) 2006-03-15

Family

ID=24508762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97915189T ATE318307T1 (de) 1996-04-01 1997-03-24 Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen.

Country Status (13)

Country Link
US (1) US5905042A (de)
EP (1) EP0938550B1 (de)
JP (1) JP2000507827A (de)
CN (1) CN100335625C (de)
AT (1) ATE318307T1 (de)
AU (1) AU717529B2 (de)
BR (1) BR9710652A (de)
CA (1) CA2250834A1 (de)
DE (1) DE69735293T2 (de)
ES (1) ES2259189T3 (de)
IL (1) IL126416A (de)
NZ (1) NZ332159A (de)
WO (1) WO1997037009A1 (de)

Families Citing this family (52)

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US5480772A (en) 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5994619A (en) * 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
US5905042A (en) * 1996-04-01 1999-05-18 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from bovine or porcine embryos
US20060021070A1 (en) * 1996-04-01 2006-01-26 University of Massachusetts, a Public Institution of Higher Education of the Commonwealth of MA Production of chimeric bovine or porcine animals using cultured inner cell mass
US7696404B2 (en) * 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
US6215041B1 (en) * 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
GB9703550D0 (en) * 1997-02-20 1997-04-09 Ppl Therapeutics Scotland Ltd Cell mediated transgenesis
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
JP2002505100A (ja) * 1998-03-02 2002-02-19 ユニヴァーシティー オヴ マサチューセッツ アパブリック インスティテューション オヴ ハイアー エデュケイション オヴ ザ コモンウェルス オヴ マサチューセッツ リプレゼンティド バイイッツ アム 種間核移植によって作製された胚性または幹細胞様細胞株
GB9811859D0 (en) * 1998-06-02 1998-07-29 Biotech & Biolog Scien Res Biological manipulation
WO2000008924A1 (en) * 1998-08-11 2000-02-24 Perry Anthony C F Method of performing transgenesis
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
US6700037B2 (en) 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
DK1159415T3 (da) 1999-03-04 2010-05-03 Revivicor Inc Genetisk modifikation af somatiske celler og anvendelse deraf
EP1206525B1 (de) 1999-08-24 2008-11-12 Una Chen-Bettecken Verfahren zur vermehrung von stammzellen
MXPA02002653A (es) * 1999-09-13 2003-10-14 Univ Massachusetts Clonacion de cerdos usando celulas donadoras o nucleos a partir de celulas diferenciadas y produccion de porcinos pluripotentes.
EP2336297A3 (de) 1999-10-28 2011-11-16 University of Massachusetts Gynogenetische oder androgenetische Herstellung pluripotenter Zellen und Zelllinien sowie ihre Verwendung zur Herstellung differenzierter Zellen und Gewebe
GB2360522A (en) 2000-03-24 2001-09-26 Geron Corp A strategy for maintaining pregnancy
CN1468250A (zh) 2000-08-03 2004-01-14 ��ķһ����˹��̹ 在转基因动物中产生人源化抗体
IL156234A0 (en) * 2000-11-30 2004-01-04 Stemron Inc Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
US20030027331A1 (en) * 2000-11-30 2003-02-06 Yan Wen Liang Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
MXPA03005624A (es) 2000-12-22 2004-12-03 Vaurox Llc Metodos para clonar mamiferos usando cromatina reprogramada del donador o celulas donadoras.
US7491534B2 (en) * 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
NZ568250A (en) 2001-01-02 2009-07-31 Stemron Inc A method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same
WO2002073188A1 (en) * 2001-03-13 2002-09-19 Advanced Cell Technology, Inc. Method for generating replacement cells and/or tissues
US20030027330A1 (en) * 2001-04-02 2003-02-06 Robert Lanza Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells
US6830917B2 (en) 2001-12-10 2004-12-14 Baxter Healthcare S.A. Method of isolation and purification of trypsin from pronase protease and use thereof
CA2471540A1 (en) * 2001-12-28 2003-07-10 Cellartis Ab A method for the establishment of a pluripotent human blastocyst-derived stem cell line
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US7612250B2 (en) * 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
KR20060057528A (ko) 2003-04-09 2006-05-26 마제-위민스 헬스 코퍼레이션 동물에서 체세포 핵 전이와 연관된 유사분열 방추 결함을교정하는 방법
US8552254B2 (en) 2003-08-22 2013-10-08 The Jackson Laboratory Methods for maintaining genetic stability of inbred animal strains
WO2005020678A1 (en) 2003-08-22 2005-03-10 The Jackson Laboratory Methods for maintaining genetic stability of inbred animal strains
US20050272149A1 (en) 2004-06-02 2005-12-08 Life & Brain Gmbh Therapeutic delivery of adenosine into a tissue
US20060188491A1 (en) * 2004-07-15 2006-08-24 Primegen Biotech, Llc Use of nuclear material to therapeutically reprogram differentiated cells
WO2006041910A2 (en) * 2004-10-05 2006-04-20 Trustees Of The University Of Pennsylvania Stem cells derived from uniparental embryos and methods of use thereof
EP1877542A4 (de) * 2005-04-29 2008-12-31 Innovative Dairy Products Pty Verfahren zur herstellung von stammzellen oder stammzellenähnlichen zellen aus säugerembryos
CA2606979A1 (en) 2005-04-29 2006-11-09 Timber Dick Radial impulse engine, pump, and compressor systems, and associated methods of operation
CA2667073C (en) * 2006-10-24 2019-06-25 Adelaide Research And Innovation Pty Ltd Method for the isolation of pluripotent cells from a pre-implantation embryo in a culture medium free from animal serum.
US20100205678A1 (en) * 2007-01-05 2010-08-12 Overstrom Eric W Oocyte spindle-associated factors improve somatic cell cloning
WO2010108503A1 (en) 2009-03-24 2010-09-30 Life & Brain Gmbh Promotion of neuronal integration in neural stem cell grafts
CN104994728B (zh) * 2012-10-19 2019-02-15 移卵基因有限公司 用于产生遗传上优质的动物的方法
EP2981605B1 (de) 2013-04-03 2019-06-19 FUJIFILM Cellular Dynamics, Inc. Verfahren und zusammensetzungen zur kultivierung von endoderm-vorläuferzellen in einer suspension
JP6581655B2 (ja) 2014-10-14 2019-09-25 フジフィルム セルラー ダイナミクス，インコーポレイテッド 多能性幹細胞由来ケラチノサイトの生成およびケラチノサイト培養の維持

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EP0435928A1 (de) * 1988-09-21 1991-07-10 Animal Biotechnology Cambridge Limited Herleitung pluripotenter embryonaler zellinien von nutztieren
GB9003791D0 (en) * 1990-02-20 1990-04-18 Ludwig Inst Cancer Res Transgenic animals,cell lines therefrom,and their use
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
JPH09500526A (ja) * 1993-06-14 1997-01-21 ベーアーエスエフ アクツィエンゲゼルシャフト テトラサイクリン反応性プロモーターによる真核細胞の遺伝子発現の厳密な制御
US5905042A (en) * 1996-04-01 1999-05-18 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from bovine or porcine embryos

Also Published As

Publication number Publication date
EP0938550B1 (de) 2006-02-22
JP2000507827A (ja) 2000-06-27
NZ332159A (en) 2000-02-28
WO1997037009A1 (en) 1997-10-09
AU717529B2 (en) 2000-03-30
IL126416A0 (en) 1999-05-09
ES2259189T3 (es) 2006-09-16
CN1219198A (zh) 1999-06-09
CA2250834A1 (en) 1997-10-09
BR9710652A (pt) 2000-01-11
US5905042A (en) 1999-05-18
DE69735293T2 (de) 2006-11-02
EP0938550A4 (de) 2001-08-08
DE69735293D1 (de) 2006-04-27
EP0938550A1 (de) 1999-09-01
IL126416A (en) 2004-06-20
CN100335625C (zh) 2007-09-05
AU2219497A (en) 1997-10-22

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