IL126416A - Cultured inner cell mass cell lines derived from ungulate embryos - Google Patents

Cultured inner cell mass cell lines derived from ungulate embryos

Info

Publication number
IL126416A
IL126416A IL12641697A IL12641697A IL126416A IL 126416 A IL126416 A IL 126416A IL 12641697 A IL12641697 A IL 12641697A IL 12641697 A IL12641697 A IL 12641697A IL 126416 A IL126416 A IL 126416A
Authority
IL
Israel
Prior art keywords
cells
cell
cicm
icm
cultured
Prior art date
Application number
IL12641697A
Other languages
English (en)
Other versions
IL126416A0 (en
Original Assignee
Univ Massachusetts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24508762&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL126416(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Massachusetts filed Critical Univ Massachusetts
Publication of IL126416A0 publication Critical patent/IL126416A0/xx
Publication of IL126416A publication Critical patent/IL126416A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877Techniques for producing new mammalian cloned embryos
    • C12N15/8771Bovine embryos
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/235Leukemia inhibitory factor [LIF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Environmental Sciences (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IL12641697A 1996-04-01 1997-03-24 Cultured inner cell mass cell lines derived from ungulate embryos IL126416A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/626,054 US5905042A (en) 1996-04-01 1996-04-01 Cultured inner cell mass cell lines derived from bovine or porcine embryos
PCT/US1997/004736 WO1997037009A1 (en) 1996-04-01 1997-03-24 Cultured inner cell mass cell lines derived from ungulate embryos

Publications (2)

Publication Number Publication Date
IL126416A0 IL126416A0 (en) 1999-05-09
IL126416A true IL126416A (en) 2004-06-20

Family

ID=24508762

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12641697A IL126416A (en) 1996-04-01 1997-03-24 Cultured inner cell mass cell lines derived from ungulate embryos

Country Status (13)

Country Link
US (1) US5905042A (de)
EP (1) EP0938550B1 (de)
JP (1) JP2000507827A (de)
CN (1) CN100335625C (de)
AT (1) ATE318307T1 (de)
AU (1) AU717529B2 (de)
BR (1) BR9710652A (de)
CA (1) CA2250834A1 (de)
DE (1) DE69735293T2 (de)
ES (1) ES2259189T3 (de)
IL (1) IL126416A (de)
NZ (1) NZ332159A (de)
WO (1) WO1997037009A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480772A (en) 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
US5905042A (en) * 1996-04-01 1999-05-18 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from bovine or porcine embryos
US5994619A (en) * 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
US20060021070A1 (en) * 1996-04-01 2006-01-26 University of Massachusetts, a Public Institution of Higher Education of the Commonwealth of MA Production of chimeric bovine or porcine animals using cultured inner cell mass
US7696404B2 (en) * 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6215041B1 (en) 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
GB9703550D0 (en) * 1997-02-20 1997-04-09 Ppl Therapeutics Scotland Ltd Cell mediated transgenesis
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
US6331659B1 (en) 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
BR9908499A (pt) * 1998-03-02 2001-12-26 Univ Massachusetts Public Inst Linhagens celulares embrionárias ousemelhantes a tronco produzidas portransplante nuclear de espécies cruzado
GB9811859D0 (en) * 1998-06-02 1998-07-29 Biotech & Biolog Scien Res Biological manipulation
CA2340242A1 (en) * 1998-08-11 2000-02-24 Teruhiko Wakayama Method of performing transgenesis
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
US6700037B2 (en) 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
NZ514620A (en) 1999-03-04 2004-04-30 Ppl Therapeutics Scotland Ltd Genetic modification of somatic cells and uses thereof
EP1206525B1 (de) 1999-08-24 2008-11-12 Una Chen-Bettecken Verfahren zur vermehrung von stammzellen
CN1377225A (zh) * 1999-09-13 2002-10-30 马萨诸塞大学 使用来自分化细胞的供体细胞或细胞核克隆猪以及多能猪的生成
MXPA02004233A (es) 1999-10-28 2004-02-17 Univ Massachusetts Produccion ginogenetica o androgenetica de celulas pluripotentes y lineas celulares, y uso de las mismas para producir celulas diferenciadas y tejidos.
GB2360522A (en) 2000-03-24 2001-09-26 Geron Corp A strategy for maintaining pregnancy
EA013564B1 (ru) 2000-08-03 2010-06-30 Терапеутик Хьюман Поликлоналз Инк. Гуманизированный иммуноглобулин и содержащая его фармацевтическая композиция
US20030027331A1 (en) * 2000-11-30 2003-02-06 Yan Wen Liang Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
AU2001297880B2 (en) * 2000-11-30 2007-05-31 Stemron Inc. Isolated homozygous stem cells differentiated cells derived therefrom and materials and methods for making and using same
US7491534B2 (en) * 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
MXPA03005624A (es) * 2000-12-22 2004-12-03 Vaurox Llc Metodos para clonar mamiferos usando cromatina reprogramada del donador o celulas donadoras.
KR20030088023A (ko) 2001-01-02 2003-11-15 스템론 인크. 미리 선별된 면역형 및(또는) 유전자형을 갖는 동형접합성간세포 군집의 제조 방법, 그로부터 유래된 이식에 적합한세포, 및 이들을 사용하는 재료 및 방법
WO2002073188A1 (en) * 2001-03-13 2002-09-19 Advanced Cell Technology, Inc. Method for generating replacement cells and/or tissues
WO2002078449A2 (en) * 2001-04-02 2002-10-10 Advanced Cell Technology, Inc. Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells
US6830917B2 (en) 2001-12-10 2004-12-14 Baxter Healthcare S.A. Method of isolation and purification of trypsin from pronase protease and use thereof
JP2005512593A (ja) * 2001-12-28 2005-05-12 セルアーティス アーベー 多能性のヒト胚盤胞由来幹細胞株の樹立方法
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
US7612250B2 (en) 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
EP1615492A4 (de) 2003-04-09 2010-07-14 Magee Womens Health Corp Verfahren zur korrektur von mitose-spindeldefekten beim somatischen zellkerntransfer bei tieren
US8552254B2 (en) 2003-08-22 2013-10-08 The Jackson Laboratory Methods for maintaining genetic stability of inbred animal strains
JP5072359B2 (ja) 2003-08-22 2012-11-14 ザ ジャクソン ラボラトリー 近交系動物の遺伝的安定性を維持するための方法
US20050272149A1 (en) 2004-06-02 2005-12-08 Life & Brain Gmbh Therapeutic delivery of adenosine into a tissue
US20060188491A1 (en) * 2004-07-15 2006-08-24 Primegen Biotech, Llc Use of nuclear material to therapeutically reprogram differentiated cells
WO2006041910A2 (en) * 2004-10-05 2006-04-20 Trustees Of The University Of Pennsylvania Stem cells derived from uniparental embryos and methods of use thereof
KR20080025366A (ko) 2005-04-29 2008-03-20 텐딕스 디벨롭먼트, 엘엘씨 래디얼 임펄스 엔진, 펌프 및 압축기 시스템과 관련 동작방법
NZ563603A (en) * 2005-04-29 2010-10-29 Innovative Dairy Products Pty A method for producing stem cells or stem cell-like cells from mammalian embryos
JP2010507373A (ja) * 2006-10-24 2010-03-11 アデレード リサーチ アンド イノベイション ピーティーワイ エルティーディー 動物血清を含まない培地中で着床前胚から多能性細胞を単離するための方法
WO2008085891A1 (en) * 2007-01-05 2008-07-17 Worcester Polytechnic Institute Oocyte spindle-associated factors improve somatic cell cloning
WO2010108503A1 (en) 2009-03-24 2010-09-30 Life & Brain Gmbh Promotion of neuronal integration in neural stem cell grafts
CA2895204C (en) * 2012-10-19 2022-06-28 Trans Ova Genetics, L.C. Methods for generating genetically superior animals
AU2014248167B2 (en) 2013-04-03 2019-10-10 FUJIFILM Cellular Dynamics, Inc. Methods and compositions for culturing endoderm progenitor cells in suspension
EP3207122B1 (de) 2014-10-14 2019-05-08 FUJIFILM Cellular Dynamics, Inc. Erzeugung von keratinozyten aus pluripotenten stammzellen und erhaltung von keratinozytenkulturen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04500909A (ja) * 1988-09-21 1992-02-20 アニマル バイオテクノロジー ケンブリッジ リミティド 家畜からの多能性胚細胞系の誘導
GB9003791D0 (en) * 1990-02-20 1990-04-18 Ludwig Inst Cancer Res Transgenic animals,cell lines therefrom,and their use
US5523226A (en) * 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
JPH09500526A (ja) * 1993-06-14 1997-01-21 ベーアーエスエフ アクツィエンゲゼルシャフト テトラサイクリン反応性プロモーターによる真核細胞の遺伝子発現の厳密な制御
US5905042A (en) * 1996-04-01 1999-05-18 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Cultured inner cell mass cell lines derived from bovine or porcine embryos

Also Published As

Publication number Publication date
IL126416A0 (en) 1999-05-09
DE69735293T2 (de) 2006-11-02
EP0938550A4 (de) 2001-08-08
DE69735293D1 (de) 2006-04-27
CA2250834A1 (en) 1997-10-09
AU2219497A (en) 1997-10-22
ATE318307T1 (de) 2006-03-15
BR9710652A (pt) 2000-01-11
ES2259189T3 (es) 2006-09-16
CN1219198A (zh) 1999-06-09
EP0938550B1 (de) 2006-02-22
CN100335625C (zh) 2007-09-05
AU717529B2 (en) 2000-03-30
US5905042A (en) 1999-05-18
JP2000507827A (ja) 2000-06-27
WO1997037009A1 (en) 1997-10-09
NZ332159A (en) 2000-02-28
EP0938550A1 (de) 1999-09-01

Similar Documents

Publication Publication Date Title
EP0938550B1 (de) Kultur einer zelllinieaus der inneren zellmasse von huftierembryonen.
US5994619A (en) Production of chimeric bovine or porcine animals using cultured inner cell mass cells
US6395958B1 (en) Method of producing a polypeptide in an ungulate
AU745334B2 (en) Method of cloning animals
US20050210537A1 (en) Pluripotent mammalian cells
US6194635B1 (en) Embryonic germ cells, method for making same, and using the cells to produce a chimeric porcine
US6545199B1 (en) Embryonic germ cells, method for making same, and using the cells to produce a chimeric porcine
US7652192B2 (en) Cloning of transgenic unglulates comprising artificial chromosomes
AU2002252076A1 (en) Cloning of transgenic animals comprising artificial chromosomes
US20060021070A1 (en) Production of chimeric bovine or porcine animals using cultured inner cell mass
JP2005523685A (ja) 体細胞由来胚幹細胞及びそれらの分化子孫
EP0855441A2 (de) Isolierung und Reinigung von Stammzellen mit magnetischen Kugeln, die wie Antikörper funktionieren, und Verfahren zur Preparation einer Stammzellinie
MXPA98008103A (en) Cellular lines of internal cellular mass cultivated derivatives of embryos ungula
WO2005040361A1 (ja) 幹細胞の簡易調製法およびそれに使用するフィーダー細胞
AU782358B2 (en) Method of cloning animals
HK1019769A (en) Cultured inner cell mass cell lines derived from ungulate embryos
EP1611785A1 (de) Klonieren von transgenen Huftieren mit künstlichen Chromosomen

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees