ATE318903T1 - Modulatoren für die regenerierung von gewebe - Google Patents

Modulatoren für die regenerierung von gewebe

Info

Publication number
ATE318903T1
ATE318903T1 AT97932145T AT97932145T ATE318903T1 AT E318903 T1 ATE318903 T1 AT E318903T1 AT 97932145 T AT97932145 T AT 97932145T AT 97932145 T AT97932145 T AT 97932145T AT E318903 T1 ATE318903 T1 AT E318903T1
Authority
AT
Austria
Prior art keywords
modulators
tissue regeneration
purified
new
nucleic acid
Prior art date
Application number
AT97932145T
Other languages
English (en)
Inventor
Michele Sanicola-Nadel
Joseph V Bonventre
Catherine A Hession
Takaharu Ichimura
Henry Wei
Richard L Cate
Original Assignee
Biogen Idec Inc
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26690881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE318903(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Inc, Gen Hospital Corp filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of ATE318903T1 publication Critical patent/ATE318903T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Electrotherapy Devices (AREA)
AT97932145T 1996-05-24 1997-05-23 Modulatoren für die regenerierung von gewebe ATE318903T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1822896P 1996-05-24 1996-05-24
US2344296P 1996-08-23 1996-08-23

Publications (1)

Publication Number Publication Date
ATE318903T1 true ATE318903T1 (de) 2006-03-15

Family

ID=26690881

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97932145T ATE318903T1 (de) 1996-05-24 1997-05-23 Modulatoren für die regenerierung von gewebe

Country Status (26)

Country Link
US (4) US6664385B1 (de)
EP (2) EP0907735B9 (de)
JP (3) JP4602482B2 (de)
CN (1) CN1147584C (de)
AT (1) ATE318903T1 (de)
AU (1) AU712289B2 (de)
BG (1) BG64678B1 (de)
BR (1) BR9709115A (de)
CA (1) CA2257851C (de)
CZ (1) CZ295936B6 (de)
DE (1) DE69735364T3 (de)
DK (1) DK0907735T5 (de)
EA (1) EA004402B1 (de)
EE (1) EE04817B1 (de)
ES (1) ES2258793T5 (de)
HU (1) HU226205B1 (de)
IL (1) IL127162A (de)
IS (1) IS2636B (de)
NO (2) NO327597B1 (de)
NZ (1) NZ336467A (de)
PL (1) PL188826B1 (de)
PT (1) PT907735E (de)
SI (1) SI0907735T2 (de)
SK (1) SK285461B6 (de)
TR (1) TR199802421T2 (de)
WO (1) WO1997044460A1 (de)

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DK1401869T3 (da) * 2001-06-01 2008-04-28 Biogen Idec Inc Molekyler og fremgangsmåder til inhibering af udskillkelse af kim 1
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Also Published As

Publication number Publication date
NZ336467A (en) 2000-10-27
BG102967A (bg) 2000-05-31
PL188826B1 (pl) 2005-04-29
SK160998A3 (en) 1999-07-12
JP4316640B2 (ja) 2009-08-19
DE69735364D1 (de) 2006-04-27
AU712289B2 (en) 1999-11-04
EA004402B1 (ru) 2004-04-29
ES2258793T5 (es) 2010-01-25
SI0907735T2 (sl) 2010-01-29
CZ381398A3 (cs) 1999-05-12
US20070141590A1 (en) 2007-06-21
PL330313A1 (en) 1999-05-10
ES2258793T3 (es) 2006-09-01
EP0907735B1 (de) 2006-03-01
JP4602482B2 (ja) 2010-12-22
IL127162A (en) 2007-07-24
DK0907735T4 (da) 2009-12-21
BG64678B1 (bg) 2005-11-30
NO327597B1 (no) 2009-08-31
HUP9902770A3 (en) 2001-09-28
JP2001505761A (ja) 2001-05-08
JP2008067701A (ja) 2008-03-27
EE04817B1 (et) 2007-04-16
CZ295936B6 (cs) 2005-12-14
CN1147584C (zh) 2004-04-28
CN1223685A (zh) 1999-07-21
US20050089868A1 (en) 2005-04-28
DK0907735T3 (da) 2006-06-26
IL127162A0 (en) 1999-09-22
PT907735E (pt) 2006-06-30
DE69735364T3 (de) 2010-05-06
HU226205B1 (en) 2008-06-30
US6664385B1 (en) 2003-12-16
NO20090945L (no) 1999-01-25
EP0907735B2 (de) 2009-10-07
EA199801044A1 (ru) 1999-04-29
NO985427L (no) 1999-01-25
DE69735364T2 (de) 2006-11-30
EP0907735B9 (de) 2010-05-19
IS2636B (is) 2010-06-15
DK0907735T5 (da) 2010-06-14
SI0907735T1 (sl) 2006-08-31
CA2257851C (en) 2011-11-15
US20060286031A1 (en) 2006-12-21
AU3567697A (en) 1997-12-09
EP0907735A1 (de) 1999-04-14
IS4902A (is) 1998-11-20
HK1021746A1 (en) 2000-06-30
NO985427D0 (no) 1998-11-20
TR199802421T2 (xx) 1999-02-22
WO1997044460A1 (en) 1997-11-27
HUP9902770A2 (hu) 1999-12-28
SK285461B6 (sk) 2007-02-01
CA2257851A1 (en) 1997-11-27
BR9709115A (pt) 1999-08-03
EE9800409A (et) 1999-06-15
JP2009039111A (ja) 2009-02-26
EP1655367A1 (de) 2006-05-10

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