ATE31931T1 - Peptide und ihre verwendung in der therapie. - Google Patents

Peptide und ihre verwendung in der therapie.

Info

Publication number
ATE31931T1
ATE31931T1 AT84306950T AT84306950T ATE31931T1 AT E31931 T1 ATE31931 T1 AT E31931T1 AT 84306950 T AT84306950 T AT 84306950T AT 84306950 T AT84306950 T AT 84306950T AT E31931 T1 ATE31931 T1 AT E31931T1
Authority
AT
Austria
Prior art keywords
phe
cys
peptides
therapy
thr
Prior art date
Application number
AT84306950T
Other languages
English (en)
Inventor
David H Coy
William A Murphy
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Application granted granted Critical
Publication of ATE31931T1 publication Critical patent/ATE31931T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT84306950T 1983-10-11 1984-10-11 Peptide und ihre verwendung in der therapie. ATE31931T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/540,380 US4485101A (en) 1983-10-11 1983-10-11 Peptides
EP84306950A EP0142272B1 (de) 1983-10-11 1984-10-11 Peptide und ihre Verwendung in der Therapie

Publications (1)

Publication Number Publication Date
ATE31931T1 true ATE31931T1 (de) 1988-01-15

Family

ID=24155205

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84306950T ATE31931T1 (de) 1983-10-11 1984-10-11 Peptide und ihre verwendung in der therapie.

Country Status (7)

Country Link
US (1) US4485101A (de)
EP (1) EP0142272B1 (de)
JP (1) JPH0635479B2 (de)
AT (1) ATE31931T1 (de)
CA (1) CA1265899A (de)
DE (1) DE3468688D1 (de)
ZA (1) ZA847960B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240912A (en) * 1983-05-09 1993-08-31 Todaro George J Transforming growth factor (TGF) peptides
US4863899A (en) * 1983-05-09 1989-09-05 Todaro George J Biologically active polypeptides
JPS6034997A (ja) * 1983-05-09 1985-02-22 ジヨージ、ジヨセフ、トダロ 生物学的活性ポリペプチド類
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4853371A (en) * 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
GB8620035D0 (en) * 1986-08-18 1986-10-01 Sandoz Ltd Organic compounds
US4871717A (en) * 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
GB2239178B (en) * 1987-07-10 1991-11-27 Sandoz Ltd Somatostatin analogues for the treatment of breast cancer
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
GB8813160D0 (en) * 1988-06-03 1988-07-06 Soc D Etudes Prod Chimique Therapeutic methods
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
ES2091907T3 (es) * 1989-12-08 1996-11-16 Univ Tulane Analogos octapeptidos de somatostina con una threonina en la sexta posicion.
ATE181240T1 (de) * 1991-02-08 1999-07-15 Biomeasure Inc Verwendung von somatostatinanalogen zur behandlung von melanomen
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
EP0981364B1 (de) * 1997-05-13 2006-03-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Methoden und zusammensetzungen zur behandlung der hyperlipidämie
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
CA2290592A1 (en) * 1997-05-13 1998-11-19 Michael Anthony Cawthorne Somatostatin and somatostatin agonists for decreasing body weight
CA2289499C (en) * 1997-05-13 2010-02-23 Michael Anthony Cawthorne Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
CA2246791A1 (en) * 1998-09-01 2000-03-01 Alison Buchan Treatment of endothelium with somatostatin analogues
JP2002089791A (ja) * 2000-09-14 2002-03-27 Sumitomo Precision Prod Co Ltd 液化ガス気化装置
JP2002340296A (ja) * 2001-05-16 2002-11-27 Sumitomo Precision Prod Co Ltd 液化ガス気化・加熱装置
NZ530007A (en) 2001-06-08 2006-02-24 Sod Conseils Rech Applic Somatostatin-dopamine chimeric analogues that retain both somatostatin and dopamine activity in vivo and display enhanced biological activity
ES2372685T3 (es) * 2002-03-29 2012-01-25 Excelerate Energy Limited Partnership Procedimiento y equipo para la regasificación de gnl a bordo de un carguero.
JP2006522100A (ja) * 2003-03-10 2006-09-28 バイオジェン アイデック インク 標的化ペプチドに対するチオール媒介性薬物結合
CA2523197C (en) 2003-04-22 2016-05-24 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Peptide vectors
FI20031454A0 (fi) 2003-10-06 2003-10-06 Juvantia Pharma Ltd Oy Selektiivisiä somatostatiinireseptori 1 ja/tai 4 -agonisteja ja -antagonisteja
WO2006123020A1 (en) * 2005-05-18 2006-11-23 Juvantia Pharma Ltd Oy Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4
SG185008A1 (en) 2010-05-20 2012-11-29 Excelerate Energy Ltd Partnership Systems and methods for treatment of lng cargo tanks
EP3007704B1 (de) 2013-06-13 2021-01-06 Antisense Therapeutics Ltd Kombinationstherapie der akromegalie
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions
JP7099717B2 (ja) 2019-09-30 2022-07-12 株式会社理研バイオ ソマトスタチン受容体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2416048A1 (de) * 1974-04-03 1975-10-30 Hoechst Ag Neue peptide mit biologischer wirkung
DE2519656A1 (de) * 1974-05-13 1975-11-27 Sandoz Ag Neue peptide und verfahren zu ihrer herstellung
DE2608336A1 (de) * 1975-03-11 1976-09-30 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
US4372884A (en) * 1975-08-06 1983-02-08 The Salk Institute For Biological Studies Pharmaceutically active peptides
US4133782A (en) * 1976-06-07 1979-01-09 The Salk Institute For Biological Studies Somatostatin analogs with dissociated biological activities
US4190575A (en) * 1977-12-27 1980-02-26 American Home Products Corporation Polypeptides related to somatostatin
GB1578402A (en) * 1977-02-22 1980-11-05 American Home Prod Somatostatin peptide analogues
US4211693A (en) * 1977-09-20 1980-07-08 The Salk Institute For Biological Studies Peptides with para-substituted phenylalanine
CA1107273A (en) * 1978-05-19 1981-08-18 Chester A. Meyers Somatostatin analogs having a substituted tryptophyl residue in position eight
US4215039A (en) * 1979-02-15 1980-07-29 American Home Products Corporation Somatostatin analogues
US4209426A (en) * 1979-05-29 1980-06-24 American Home Products Corporation Polypeptides related to somatostatin
US4369179A (en) * 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides

Also Published As

Publication number Publication date
ZA847960B (en) 1985-06-26
DE3468688D1 (en) 1988-02-18
US4485101A (en) 1984-11-27
EP0142272B1 (de) 1988-01-13
JPS60149599A (ja) 1985-08-07
CA1265899A (en) 1990-02-13
JPH0635479B2 (ja) 1994-05-11
EP0142272A1 (de) 1985-05-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee