ATE319457T1 - Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu - Google Patents
Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazuInfo
- Publication number
- ATE319457T1 ATE319457T1 AT99915411T AT99915411T ATE319457T1 AT E319457 T1 ATE319457 T1 AT E319457T1 AT 99915411 T AT99915411 T AT 99915411T AT 99915411 T AT99915411 T AT 99915411T AT E319457 T1 ATE319457 T1 AT E319457T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- iatrogenic
- age
- derivatives
- treatment
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 2
- 230000000642 iatrogenic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003697 vitamin B6 derivatives Chemical class 0.000 title 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 6
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 4
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 4
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 3
- 239000013589 supplement Substances 0.000 abstract 3
- 239000011726 vitamin B6 Substances 0.000 abstract 3
- 235000019158 vitamin B6 Nutrition 0.000 abstract 3
- 229940011671 vitamin b6 Drugs 0.000 abstract 3
- 230000032683 aging Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/061,173 US6051587A (en) | 1998-04-16 | 1998-04-16 | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319457T1 true ATE319457T1 (de) | 2006-03-15 |
Family
ID=22034118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99915411T ATE319457T1 (de) | 1998-04-16 | 1999-04-16 | Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6051587A (de) |
| EP (1) | EP1071430B1 (de) |
| JP (1) | JP2002512194A (de) |
| AT (1) | ATE319457T1 (de) |
| AU (1) | AU765749B2 (de) |
| BR (1) | BR9909672A (de) |
| CA (1) | CA2328730C (de) |
| DE (1) | DE69930243T2 (de) |
| ES (1) | ES2260906T3 (de) |
| IL (1) | IL139681A0 (de) |
| NZ (1) | NZ508142A (de) |
| WO (1) | WO1999053928A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716858B1 (en) | 1995-08-28 | 2004-04-06 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| ES2250112T3 (es) | 1999-03-08 | 2006-04-16 | Medicure Inc. | Analogos de piridoxal para el tratamiento de trastornos causados por carencia de vitamina b6. |
| US6489345B1 (en) * | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
| WO2001013900A2 (en) | 1999-08-24 | 2001-03-01 | Medicure International Inc. | Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
| US7442689B2 (en) | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| AU2001237185B2 (en) | 2000-02-29 | 2006-02-02 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| EP1531157B1 (de) * | 2000-02-29 | 2008-03-19 | Medicure International Inc. | Cardioprotektive Phosphonate |
| WO2001072309A2 (en) | 2000-03-28 | 2001-10-04 | Medicure International Inc. | Treatment of cerebrovascular disease |
| WO2001078721A1 (en) * | 2000-04-13 | 2001-10-25 | Mayo Foundation For Medical Education And Research | Aβ42 LOWERING AGENTS |
| US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| US6521645B2 (en) | 2000-11-20 | 2003-02-18 | The University Of Kansas Medical Center | Methods for the treatment and prevention of urinary stone disease |
| US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
| US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
| US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
| EP2392562B1 (de) * | 2002-07-29 | 2018-03-07 | Cardax Pharma, Inc. | Strukturelle Carotenoidanaloge zur Hemmung und Abschwächung einer Erkrankung |
| US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
| US7723327B2 (en) | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
| US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
| US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
| US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
| US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
| US7763649B2 (en) | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
| US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
| US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| WO2004071431A2 (en) * | 2003-02-05 | 2004-08-26 | Myriad Genetics, Inc. | Method and composition for treating neurodegenerative disorders |
| AU2004224566A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Compositions for treating angina |
| CA2520403A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Modulation of cell death |
| EP1651195A4 (de) * | 2003-07-11 | 2007-10-03 | Myriad Genetics Inc | Pharmazeutische verfahren, dosierschemata und dosierformen zur behandlung von alzheimerkrankheit |
| WO2006001877A2 (en) * | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| EP1750723A1 (de) * | 2004-04-14 | 2007-02-14 | Hawaii Biotech, Inc. | Carotenoid-analoga oder derivate zur hemmung und linderung von entzündungen |
| US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| EP1745180A1 (de) * | 2004-04-29 | 2007-01-24 | Keystone Retaining Wall Systems, Inc. | Frontverkleidung für stützwände |
| US20060019929A1 (en) * | 2004-07-07 | 2006-01-26 | Albert Friesen | Combination therapies employing platelet aggregation drugs |
| AU2005270701A1 (en) * | 2004-08-10 | 2006-02-16 | Medicure International Inc. | Combination therapies employing vitamin B6 related compounds and ACE inhibitors and uses thereof for the treatment of diabetic disorders |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| WO2006020853A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
| CA2585165A1 (en) * | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
| JP2008521756A (ja) * | 2004-11-26 | 2008-06-26 | メディキュア インターナショナル インコーポレイテッド | ピリドキサール−5’−ホスフェートの新規配合物及び調製方法 |
| AU2006204563A1 (en) * | 2005-01-05 | 2006-07-13 | Medicure International Inc. | Compounds and methods for regulating triglyceride levels |
| US20060270590A1 (en) | 2005-03-29 | 2006-11-30 | Lockwood Samuel F | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof |
| CA2503087A1 (en) * | 2005-03-30 | 2006-09-30 | Medicure International Inc. | Intravenous formulations of pyridoxal 5'-phosphate and method of preparation |
| JP2009502807A (ja) * | 2005-07-22 | 2009-01-29 | ミリアド ジェネティクス, インコーポレイテッド | 薬剤含有率の高い製剤および投与量形態 |
| JP2009517411A (ja) * | 2005-11-28 | 2009-04-30 | メディキュア インターナショナル インコーポレーテッド | 心血管及び関連病状の処置のための調剤 |
| DOP2007000055A (es) | 2006-04-10 | 2007-10-31 | Senosiain S A De C V Lab | Composición farmaceutica que comprende un analgésico y vitaminas |
| US20080033045A1 (en) * | 2006-07-07 | 2008-02-07 | Myriad Genetics, Incorporated | Treatment of psychiatric disorders |
| MX2008003230A (es) * | 2008-03-07 | 2009-09-07 | Senosiain S A De C V Lab | Composicion famaceutica oral que comprende la combinacion de una sal de ketorolaco y vitaminas del complejo b. |
| ITMI20121316A1 (it) | 2012-07-27 | 2014-01-28 | Altergon Sa | Complessi di condroitina ad assorbimento transcutaneo |
| WO2014063134A1 (en) * | 2012-10-19 | 2014-04-24 | New York University | Methods for inhibiting osteolysis |
| RU2629367C1 (ru) * | 2016-11-02 | 2017-08-29 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Нестероидное противовоспалительное средство на основе напроксена, обладающее низкой гастротоксичностью |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR4492M (de) * | 1965-07-07 | 1966-10-10 | ||
| FR6707M (de) * | 1966-04-29 | 1969-02-17 | ||
| FR6723M (de) * | 1966-12-30 | 1969-02-17 | ||
| FR7503M (de) * | 1967-05-30 | 1969-12-08 | ||
| GB1236531A (en) * | 1969-02-12 | 1971-06-23 | Soc D Etudes Prod Chimique | Adenin derivative |
| JPS53121765A (en) * | 1977-04-01 | 1978-10-24 | Chugai Pharmaceut Co Ltd | Pyridoxal derivatives |
| IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
| US4542026A (en) * | 1983-04-29 | 1985-09-17 | Jose Rios | Method of treating vasomotor disorders |
| US4579846A (en) * | 1984-10-11 | 1986-04-01 | Pfizer Inc. | Antiinflammatory compositions and methods |
| FR2641189B1 (fr) * | 1988-06-20 | 1991-05-10 | Timol Mamoojee | Compositions pharmaceutiques contenant de l'acide acetyl salicylique et de la vitamine b6 |
| US20040180865A1 (en) * | 1993-06-04 | 2004-09-16 | Jeffry W. Kreamer | Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease |
-
1998
- 1998-04-16 US US09/061,173 patent/US6051587A/en not_active Expired - Fee Related
-
1999
- 1999-04-16 NZ NZ508142A patent/NZ508142A/xx unknown
- 1999-04-16 AT AT99915411T patent/ATE319457T1/de not_active IP Right Cessation
- 1999-04-16 ES ES99915411T patent/ES2260906T3/es not_active Expired - Lifetime
- 1999-04-16 JP JP2000544332A patent/JP2002512194A/ja not_active Withdrawn
- 1999-04-16 IL IL13968199A patent/IL139681A0/xx unknown
- 1999-04-16 WO PCT/CA1999/000331 patent/WO1999053928A1/en not_active Ceased
- 1999-04-16 BR BRPI9909672-2A patent/BR9909672A/pt not_active Application Discontinuation
- 1999-04-16 EP EP99915411A patent/EP1071430B1/de not_active Expired - Lifetime
- 1999-04-16 DE DE69930243T patent/DE69930243T2/de not_active Expired - Fee Related
- 1999-04-16 CA CA002328730A patent/CA2328730C/en not_active Expired - Fee Related
- 1999-04-16 AU AU34029/99A patent/AU765749B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2260906T3 (es) | 2006-11-01 |
| DE69930243D1 (de) | 2006-05-04 |
| AU765749B2 (en) | 2003-09-25 |
| CA2328730C (en) | 2007-08-21 |
| WO1999053928A1 (en) | 1999-10-28 |
| CA2328730A1 (en) | 1999-10-28 |
| AU3402999A (en) | 1999-11-08 |
| BR9909672A (pt) | 2007-07-31 |
| EP1071430B1 (de) | 2006-03-08 |
| NZ508142A (en) | 2002-11-26 |
| JP2002512194A (ja) | 2002-04-23 |
| DE69930243T2 (de) | 2006-12-07 |
| IL139681A0 (en) | 2002-02-10 |
| US6051587A (en) | 2000-04-18 |
| EP1071430A1 (de) | 2001-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE319457T1 (de) | Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu | |
| TR200002207T1 (tr) | Slekoksib bileşikleri. | |
| US6629835B2 (en) | Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2 | |
| US20020077350A1 (en) | Compositions exhibiting synergistic inhibition of the expression and/or activity of clyclooxygenase-2 | |
| BR9607066A (pt) | Método, composições e conjuntos para aumentar a biodisponibilidade oral de agentes farmacêuticos | |
| BR9709838A (pt) | Regime de administração que fornece um perfil de plasma no sangue de um inibidor de h+,k+-atpase composição farmacêutica oral uso da mesma e de inibidor h+,k+-atpase e processos para melhorar a inibição de secreção de ácido gástrico e o efeito terapêutico no tratamento de perturbações gastrintestinais e para receber um perfil estendido de plasma de um inibidor de h+,k+-atpase | |
| NO964864L (no) | Orale, flytende alendronatpreparater | |
| WO2009051628A2 (en) | Transdermal treatment device and method | |
| KR970061244A (ko) | 치매 치료용 약학 조성물 | |
| BRPI0014874B1 (pt) | Composição compreendendo extrato de folhas de vinha vermelha | |
| RU2701720C1 (ru) | Комбинации пальмитоилэтаноламида для лечения хронической боли | |
| AR030039A1 (es) | Composicion farmaceutica que comprende una droga inhibidora selectiva de la ciclooxigenasa-2, su uso en la fabricacion de un medicamento para tratar o prevenir afecciones mediadas por la ciclooxigenasa-2 y metodo para hacer dicho medicamento | |
| ATE305469T1 (de) | Sulfonsäure- oder sulfonylamino-n-(heteroaralkyl)-azaheterozyklyl midverbindungen | |
| AR035946A1 (es) | Composiciones farmaceuticas estrogenicas para usar en el tratamiento de desordenes en mujeres perimenopausicas, menopausicas o posmenopausicas, y usos de dichas composiciones para la preparacion de medicamentos | |
| TR200101163T2 (tr) | Safra suyu ikameli fenil-alkenoilguanidinler, üretim yöntemleri, kullanımları | |
| RU2000114174A (ru) | Применение фосфолипидных комплексов экстрактов из vitis vinifera в качестве противоатеросклеротических агентов | |
| BRPI0415322A (pt) | composição farmacêutica antiretroviral, processo para a preparação de uma composição farmacêutica antiretroviral, método para reduzir a carga de consumo de pìlulas para um paciente, método para aumentar a meia-vida in vivo de lamivudina e de zidovudina enquanto não afetando a meia-vida de nevirapina | |
| RU2008122964A (ru) | Азитромицин для лечения гранулематозных розовых (красных) угрей | |
| RU2180591C2 (ru) | Средство для лечения сексуальных дисфункций у мужчин | |
| EA003792B1 (ru) | Применение комбинации витаминов для лечения зуда и неинфекционных заболеваний, приводящих к зуду и/или воспалению | |
| JP4706174B2 (ja) | α−グルコシダーゼ阻害剤 | |
| RU2182823C1 (ru) | Способ лечения больных псориазом в сочетании с хроническим описторхозом | |
| DE50202865D1 (de) | Herstellung reiner stereoisomere von tricyclo-[5.2.1.0(2.6) ]-dec-9-yl-xanthogenat sowie deren verwendung als arzneimittel | |
| Fitzpatrick | Melatonin in health and disease | |
| Petry et al. | Medicinal herbs: answers and advice, part 2 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |