ATE319500T1 - Kombinierte elektroporation- und iontophoresevorrichtung zur medikament- und genverabreichung - Google Patents

Kombinierte elektroporation- und iontophoresevorrichtung zur medikament- und genverabreichung

Info

Publication number
ATE319500T1
ATE319500T1 AT99966432T AT99966432T ATE319500T1 AT E319500 T1 ATE319500 T1 AT E319500T1 AT 99966432 T AT99966432 T AT 99966432T AT 99966432 T AT99966432 T AT 99966432T AT E319500 T1 ATE319500 T1 AT E319500T1
Authority
AT
Austria
Prior art keywords
electrode assembly
electric field
stratum corneum
drug
anode
Prior art date
Application number
AT99966432T
Other languages
English (en)
Inventor
Gunter A Hofmann
Original Assignee
Genetronics Inc
Gunter A Hofmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetronics Inc, Gunter A Hofmann filed Critical Genetronics Inc
Application granted granted Critical
Publication of ATE319500T1 publication Critical patent/ATE319500T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
AT99966432T 1998-12-17 1999-12-17 Kombinierte elektroporation- und iontophoresevorrichtung zur medikament- und genverabreichung ATE319500T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/213,782 US5968006A (en) 1997-11-04 1998-12-17 Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes

Publications (1)

Publication Number Publication Date
ATE319500T1 true ATE319500T1 (de) 2006-03-15

Family

ID=22796491

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99966432T ATE319500T1 (de) 1998-12-17 1999-12-17 Kombinierte elektroporation- und iontophoresevorrichtung zur medikament- und genverabreichung

Country Status (9)

Country Link
US (1) US5968006A (de)
EP (1) EP1140283B1 (de)
AT (1) ATE319500T1 (de)
AU (1) AU763535B2 (de)
CA (1) CA2342336A1 (de)
DE (1) DE69930306T2 (de)
ES (1) ES2260957T3 (de)
TW (1) TW368420B (de)
WO (1) WO2000035533A1 (de)

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Also Published As

Publication number Publication date
AU2196900A (en) 2000-07-03
DE69930306D1 (de) 2006-05-04
EP1140283B1 (de) 2006-03-08
EP1140283A1 (de) 2001-10-10
DE69930306T2 (de) 2006-12-07
AU763535B2 (en) 2003-07-24
WO2000035533A1 (en) 2000-06-22
TW368420B (en) 1999-09-01
ES2260957T3 (es) 2006-11-01
US5968006A (en) 1999-10-19
CA2342336A1 (en) 2000-06-22

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