ATE319685T1 - Exzitatorisch wirkende aminosäurederivate - Google Patents

Exzitatorisch wirkende aminosäurederivate

Info

Publication number
ATE319685T1
ATE319685T1 AT96308216T AT96308216T ATE319685T1 AT E319685 T1 ATE319685 T1 AT E319685T1 AT 96308216 T AT96308216 T AT 96308216T AT 96308216 T AT96308216 T AT 96308216T AT E319685 T1 ATE319685 T1 AT E319685T1
Authority
AT
Austria
Prior art keywords
amino acid
acid derivatives
excitatory amino
excitatory
derivatives
Prior art date
Application number
AT96308216T
Other languages
English (en)
Inventor
James Allen Monn
Matthew John Valli
Steven Marc Massey
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605434.1A external-priority patent/GB9605434D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE319685T1 publication Critical patent/ATE319685T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96308216T 1995-11-16 1996-11-14 Exzitatorisch wirkende aminosäurederivate ATE319685T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US686495P 1995-11-16 1995-11-16
GBGB9605434.1A GB9605434D0 (en) 1996-03-15 1996-03-15 Excitatory amino acid derivatives

Publications (1)

Publication Number Publication Date
ATE319685T1 true ATE319685T1 (de) 2006-03-15

Family

ID=26308935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96308216T ATE319685T1 (de) 1995-11-16 1996-11-14 Exzitatorisch wirkende aminosäurederivate

Country Status (22)

Country Link
EP (1) EP0774461B1 (de)
KR (1) KR19990067598A (de)
CN (1) CN1202167A (de)
AR (2) AR006748A1 (de)
AT (1) ATE319685T1 (de)
AU (1) AU703409B2 (de)
BR (1) BR9611511A (de)
CA (1) CA2237910C (de)
CO (1) CO4770955A1 (de)
CZ (1) CZ150198A3 (de)
DE (1) DE69635886T2 (de)
EA (1) EA001617B1 (de)
ES (1) ES2258771T3 (de)
HU (1) HUP9903459A3 (de)
IL (1) IL124487A (de)
NO (1) NO982202L (de)
NZ (1) NZ323205A (de)
PE (1) PE17798A1 (de)
PL (1) PL326695A1 (de)
TR (1) TR199800877T2 (de)
WO (1) WO1997018199A1 (de)
YU (1) YU60796A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1014971A1 (de) * 1997-01-29 2000-07-05 Eli Lilly And Company Behandlung von prämenstruelle dysphorische störung
JP2001515839A (ja) 1997-07-18 2001-09-25 ジョージタウン・ユニバーシティ 二環式向代謝性グルタミン酸受容体リガンド
US6825211B1 (en) 1997-07-18 2004-11-30 Georgetown University Bicyclic metabotropic glutamate receptor ligands
DE19801648A1 (de) * 1998-01-17 1999-07-22 Bayer Ag alpha-Substituierte Lactone
DE19801636A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte bicyclische Lactone
DE19801647A1 (de) * 1998-01-17 1999-07-22 Bayer Ag Substituierte beta,gamma-annellierte Lactone
DE19801646A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte alpha,beta-annellierte Butyrolactone
GB2355982A (en) * 1999-11-03 2001-05-09 Lilly Co Eli Heterocyclic amino acids
TWI315666B (en) * 2002-06-11 2009-10-11 Lilly Co Eli Prodrugs of excitatory amino acids
WO2010055106A1 (en) * 2008-11-14 2010-05-20 Dsm Fine Chemicals Austria Nfg. Gmbh & Co Kg Process for the production of cyclopropane derivatives
WO2010111080A2 (en) 2009-03-27 2010-09-30 Eli Lilly And Company Optimized treatment of schizophrenia
US8735397B2 (en) 2010-03-29 2014-05-27 Vanderbilt University Method for treating schizophrenia and related diseases
KR101598679B1 (ko) 2011-06-17 2016-02-29 일라이 릴리 앤드 캄파니 mGlu2 수용체 효능제로서의 비시클로(3.1.0)헥산-2,6-디카르복실산 유도체
AR089718A1 (es) 2012-02-01 2014-09-10 Lilly Co Eli AGONISTAS DE mGlu2/3
PL3096790T3 (pl) * 2014-01-21 2020-01-31 Janssen Pharmaceutica, N.V. Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
ME03518B (de) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinationen mit positiven allosterischen modulatoren von metabotropem glutamatergen rezeptor vom subtyp 2 und deren verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2572842A (en) * 1947-08-05 1951-10-30 Du Pont The n-carboanhydride of 2-amino-4, 6, 6-trimethylheptanoic acid and polymers therefrom
US4536330A (en) * 1982-09-23 1985-08-20 International Flavors & Fragrances Inc. 1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters and cyclic condensation products thereof, organoleptic uses of same and processes for preparing same
ATE206915T1 (de) * 1994-08-12 2001-11-15 Lilly Co Eli Behandlung von angstzuständen
AU3325095A (en) * 1994-08-12 1996-03-07 Eli Lilly And Company Composition and method for protection against drug dependency
PL182285B1 (pl) * 1994-08-12 2001-12-31 Lilly Co Eli Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL

Also Published As

Publication number Publication date
AU7727996A (en) 1997-06-05
YU60796A (sh) 1998-12-23
PL326695A1 (en) 1998-10-26
CA2237910A1 (en) 1997-05-22
NO982202D0 (no) 1998-05-14
CO4770955A1 (es) 1999-04-30
HUP9903459A2 (hu) 2001-04-28
TR199800877T2 (xx) 1998-09-21
NO982202L (no) 1998-05-14
CA2237910C (en) 2005-12-27
IL124487A0 (en) 1998-12-06
AU703409B2 (en) 1999-03-25
BR9611511A (pt) 1999-05-04
EA001617B1 (ru) 2001-06-25
EP0774461A1 (de) 1997-05-21
NZ323205A (en) 1999-06-29
HUP9903459A3 (en) 2001-08-28
CZ150198A3 (cs) 1998-10-14
AR004602A1 (es) 1998-12-16
ES2258771T3 (es) 2006-09-01
IL124487A (en) 2001-01-11
EP0774461B1 (de) 2006-03-08
KR19990067598A (ko) 1999-08-25
PE17798A1 (es) 1998-04-18
AR006748A1 (es) 1999-09-29
EA199800377A1 (ru) 1998-10-29
DE69635886D1 (de) 2006-05-04
DE69635886T2 (de) 2006-10-19
WO1997018199A1 (en) 1997-05-22
CN1202167A (zh) 1998-12-16

Similar Documents

Publication Publication Date Title
ATE211131T1 (de) Arylsulfonylaminohydroxamsäurederivate
DK0696577T3 (da) Syntetiske excitatoriske aminosyrer
DE69522717D1 (de) Chinazolinderivate
DE122009000076I1 (de) Chinazolin-derivate
DE69610698D1 (de) Chinazolin-derivate
ATE199150T1 (de) Diphenylmethylenpiperidin-derivate
DE69635886D1 (de) Exzitatorisch wirkende Aminosäurederivate
BR9611509A (pt) Antagonistas de receptores de aminoácidos excitativos
FI950586A0 (fi) Aminohappojohdos
DE69606053D1 (de) Modifizierte fluorsulfonsäure
FI945354A7 (fi) Sykliset aminohappojohdannaiset
DE69604999D1 (de) Brückenverbinder
DE69601527D1 (de) Pyrrolylbenzimidazol-Derivate
BR9610239A (pt) Proteínas de fusão-alérgeno-xcd32
ATA100695A (de) Prothrombin-derivate
BR9609671A (pt) Amino uracilas substituídas
ATE240307T1 (de) Diarylalkenylamin-derivate
ATE202093T1 (de) 4-amino-benzoylguanidin-derivate
DE59610106D1 (de) Fluorbenzylether-Derivate
ATE177102T1 (de) Chromanderivate
EP0850950A4 (de) Peptidderivate
ATE225347T1 (de) Aza-anthracyclinone-derivate
EP0861849A4 (de) Peptidderivate
DE59607055D1 (de) 4-Mercapto-benzoylguanidin-Derivate
SE9503923D0 (sv) New amino acid derivatives

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties