NO982202L - Eksitatoriske aminosyrederivater - Google Patents

Eksitatoriske aminosyrederivater

Info

Publication number
NO982202L
NO982202L NO982202A NO982202A NO982202L NO 982202 L NO982202 L NO 982202L NO 982202 A NO982202 A NO 982202A NO 982202 A NO982202 A NO 982202A NO 982202 L NO982202 L NO 982202L
Authority
NO
Norway
Prior art keywords
amino acid
acid derivatives
excitatory amino
modulators
amides
Prior art date
Application number
NO982202A
Other languages
English (en)
Other versions
NO982202D0 (no
Inventor
Steven Marc Massey
James Allen Monn
Matthew John Valli
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605434.1A external-priority patent/GB9605434D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO982202D0 publication Critical patent/NO982202D0/no
Publication of NO982202L publication Critical patent/NO982202L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Forbindelser med formel (I) hvor X står for O, NR", S, SO eller SO2 og R er som definert i beskrivelsen; og ikke-toksiske metabolisk labile estere eller amider derav; og farmasøytisk akseptable salter derav, er nyttige som modulatorer for metabotrop glutamat reseptorfunksjon.
NO982202A 1995-11-16 1998-05-14 Eksitatoriske aminosyrederivater NO982202L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US686495P 1995-11-16 1995-11-16
GBGB9605434.1A GB9605434D0 (en) 1996-03-15 1996-03-15 Excitatory amino acid derivatives
PCT/US1996/018112 WO1997018199A1 (en) 1995-11-16 1996-11-12 Excitatory amino acid derivatives

Publications (2)

Publication Number Publication Date
NO982202D0 NO982202D0 (no) 1998-05-14
NO982202L true NO982202L (no) 1998-05-14

Family

ID=26308935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982202A NO982202L (no) 1995-11-16 1998-05-14 Eksitatoriske aminosyrederivater

Country Status (22)

Country Link
EP (1) EP0774461B1 (no)
KR (1) KR19990067598A (no)
CN (1) CN1202167A (no)
AR (2) AR006748A1 (no)
AT (1) ATE319685T1 (no)
AU (1) AU703409B2 (no)
BR (1) BR9611511A (no)
CA (1) CA2237910C (no)
CO (1) CO4770955A1 (no)
CZ (1) CZ150198A3 (no)
DE (1) DE69635886T2 (no)
EA (1) EA001617B1 (no)
ES (1) ES2258771T3 (no)
HU (1) HUP9903459A3 (no)
IL (1) IL124487A (no)
NO (1) NO982202L (no)
NZ (1) NZ323205A (no)
PE (1) PE17798A1 (no)
PL (1) PL326695A1 (no)
TR (1) TR199800877T2 (no)
WO (1) WO1997018199A1 (no)
YU (1) YU60796A (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998032436A1 (en) * 1997-01-29 1998-07-30 Eli Lilly And Company Treatment for premenstrual dysphoric disorder
US6825211B1 (en) 1997-07-18 2004-11-30 Georgetown University Bicyclic metabotropic glutamate receptor ligands
JP2001515839A (ja) * 1997-07-18 2001-09-25 ジョージタウン・ユニバーシティ 二環式向代謝性グルタミン酸受容体リガンド
DE19801636A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte bicyclische Lactone
DE19801647A1 (de) * 1998-01-17 1999-07-22 Bayer Ag Substituierte beta,gamma-annellierte Lactone
DE19801648A1 (de) * 1998-01-17 1999-07-22 Bayer Ag alpha-Substituierte Lactone
DE19801646A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte alpha,beta-annellierte Butyrolactone
GB2355982A (en) * 1999-11-03 2001-05-09 Lilly Co Eli Heterocyclic amino acids
TWI315666B (en) * 2002-06-11 2009-10-11 Lilly Co Eli Prodrugs of excitatory amino acids
CN102216243B (zh) * 2008-11-14 2014-09-03 Dsm精细化学奥地利Nfg两合公司 制备环丙烷衍生物的方法
WO2010111080A2 (en) 2009-03-27 2010-09-30 Eli Lilly And Company Optimized treatment of schizophrenia
US8735397B2 (en) * 2010-03-29 2014-05-27 Vanderbilt University Method for treating schizophrenia and related diseases
DK2721012T3 (en) 2011-06-17 2016-08-15 Lilly Co Eli Biclo (3.1.0) hexane-2,6-dicarboxylic acid derivatives as MGLU2 receptor agonist
AR089718A1 (es) 2012-02-01 2014-09-10 Lilly Co Eli AGONISTAS DE mGlu2/3
MX386697B (es) * 2014-01-21 2025-03-19 Janssen Pharmaceutica Nv Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2572842A (en) * 1947-08-05 1951-10-30 Du Pont The n-carboanhydride of 2-amino-4, 6, 6-trimethylheptanoic acid and polymers therefrom
US4536330A (en) * 1982-09-23 1985-08-20 International Flavors & Fragrances Inc. 1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters and cyclic condensation products thereof, organoleptic uses of same and processes for preparing same
PL182285B1 (pl) * 1994-08-12 2001-12-31 Lilly Co Eli Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL
ATE206915T1 (de) * 1994-08-12 2001-11-15 Lilly Co Eli Behandlung von angstzuständen
WO1996004900A1 (en) * 1994-08-12 1996-02-22 Eli Lilly And Company Composition and method for protection against drug dependency

Also Published As

Publication number Publication date
IL124487A0 (en) 1998-12-06
AU7727996A (en) 1997-06-05
HUP9903459A3 (en) 2001-08-28
EP0774461B1 (en) 2006-03-08
EP0774461A1 (en) 1997-05-21
NZ323205A (en) 1999-06-29
NO982202D0 (no) 1998-05-14
AR006748A1 (es) 1999-09-29
WO1997018199A1 (en) 1997-05-22
CN1202167A (zh) 1998-12-16
DE69635886T2 (de) 2006-10-19
TR199800877T2 (xx) 1998-09-21
AR004602A1 (es) 1998-12-16
PE17798A1 (es) 1998-04-18
CA2237910C (en) 2005-12-27
EA199800377A1 (ru) 1998-10-29
IL124487A (en) 2001-01-11
BR9611511A (pt) 1999-05-04
AU703409B2 (en) 1999-03-25
YU60796A (sh) 1998-12-23
PL326695A1 (en) 1998-10-26
CO4770955A1 (es) 1999-04-30
EA001617B1 (ru) 2001-06-25
HUP9903459A2 (hu) 2001-04-28
CA2237910A1 (en) 1997-05-22
KR19990067598A (ko) 1999-08-25
DE69635886D1 (de) 2006-05-04
ES2258771T3 (es) 2006-09-01
CZ150198A3 (cs) 1998-10-14
ATE319685T1 (de) 2006-03-15

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application