ATE319709T1 - Indolderivate zur behandlung von depression und angstzuständen - Google Patents

Indolderivate zur behandlung von depression und angstzuständen

Info

Publication number
ATE319709T1
ATE319709T1 AT00982252T AT00982252T ATE319709T1 AT E319709 T1 ATE319709 T1 AT E319709T1 AT 00982252 T AT00982252 T AT 00982252T AT 00982252 T AT00982252 T AT 00982252T AT E319709 T1 ATE319709 T1 AT E319709T1
Authority
AT
Austria
Prior art keywords
anxiety
depression
treatment
indole derivatives
withdrawal
Prior art date
Application number
AT00982252T
Other languages
English (en)
Inventor
Marvin Martin Hansen
John Xiaoqiang He
Nicholas Allan Honigschmidt
Daniel James Koch
Todd Jonathan Kohn
Vincent Patrick Rocco
Patrick Gianpietro Spinazze
Kumiko Takeuchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE319709T1 publication Critical patent/ATE319709T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
AT00982252T 1999-12-20 2000-12-06 Indolderivate zur behandlung von depression und angstzuständen ATE319709T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17274899P 1999-12-20 1999-12-20

Publications (1)

Publication Number Publication Date
ATE319709T1 true ATE319709T1 (de) 2006-03-15

Family

ID=22629052

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00982252T ATE319709T1 (de) 1999-12-20 2000-12-06 Indolderivate zur behandlung von depression und angstzuständen

Country Status (7)

Country Link
US (1) US7144898B2 (de)
EP (1) EP1242411B1 (de)
AT (1) ATE319709T1 (de)
AU (1) AU1930801A (de)
DE (1) DE60026581T2 (de)
ES (1) ES2259619T3 (de)
WO (1) WO2001046181A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY135686A (en) 2002-06-24 2008-06-30 Schering Corp Indole derivatives useful as histamine h3 antagonists
AR070398A1 (es) * 2008-02-22 2010-03-31 Gruenenthal Chemie Derivados sustituidos de indol
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
US11116357B2 (en) 2013-03-15 2021-09-14 Taylor Commercial Foodservice, Llc Cooking gap control of a cooking apparatus
CN108129251A (zh) * 2017-12-22 2018-06-08 上海应用技术大学 一种2-乙基苯乙烯的合成工艺
CN108314630B (zh) * 2018-02-08 2020-11-06 广西民族大学 一种肟醚类衍生物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2337461A1 (de) 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
WO1980000152A1 (fr) * 1978-07-03 1980-02-07 Sandoz Ag Derives d'un 3-aminopropoxy-aryle, leur preparation et utilisation
EP0025111B1 (de) 1979-08-10 1984-07-25 Sandoz Ag 3-Aminopropoxyaryl-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US5300498A (en) * 1993-06-04 1994-04-05 Hoechst-Roussel Pharmaceuticals Incorporated 6-piperazinyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acids, esters, amides and related compounds
US5627196A (en) * 1995-01-17 1997-05-06 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5789402A (en) * 1995-01-17 1998-08-04 Eli Lilly Company Compounds having effects on serotonin-related systems
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5912256A (en) * 1996-06-20 1999-06-15 Eli Lilly And Company Compounds having effects on serotonin-related systems
TR200100240T2 (tr) * 1998-07-27 2002-01-21 Eli Lilly And Company Anksiyete bozukluklarının tedavisi
US6242450B1 (en) * 1998-07-27 2001-06-05 Eli Lilly And Company 5-HT1F antagonists
JP3893878B2 (ja) 1999-05-24 2007-03-14 三菱ウェルファーマ株式会社 フェノキシプロピルアミン化合物

Also Published As

Publication number Publication date
DE60026581T2 (de) 2006-12-28
US20040006229A1 (en) 2004-01-08
EP1242411A1 (de) 2002-09-25
WO2001046181A1 (en) 2001-06-28
ES2259619T3 (es) 2006-10-16
US7144898B2 (en) 2006-12-05
AU1930801A (en) 2001-07-03
DE60026581D1 (de) 2006-05-04
EP1242411B1 (de) 2006-03-08

Similar Documents

Publication Publication Date Title
DE60122767D1 (de) Indoly-lsulphonyl-verbindungen zur behandlung von störungen des zns
MX9702865A (es) Agentes estrogenicos.
DE60208221D1 (de) Heterozyklische verbindungen zur behandlung von harnwegserkrankungen
CY1107747T1 (el) Υποκατεστημενα τετρακυκλικα παραγωγα πυρρολοκινολονης χρησιμα ως αναστολεις της φωσφοδιεστερασης
ATE452884T1 (de) Arylmethylamin-derivate zur verwendung als inhibitoren von tryptase
ATE260653T1 (de) Verwendung von naaladase inhibitoren zur behandlung von angstzuständen und gedächtnisstörungen
MY141528A (en) Anilinopyrazole derivatives useful for the treatment of diabetes
DE60014136D1 (de) Sapogenin derivate zur behandlung von kognitiven störungen
NO20064325L (no) Heteroarylaminopyrazolderivativer nyttige for behandling av diabetes
ATE367380T1 (de) Zur behandlung von zns-erkrankungen geeignete piperazinylchinolinderivate
DE60220385D1 (de) Benzimidazole zur behandlung sexueller fehlfunktionen
ATE302002T1 (de) Verwendung von pyrazolderivaten zur behandlung von unfruchtbarkeit
ATE290857T1 (de) Bretyliumhaltige zusammensetzungen und kits und deren verwendung zur vorbeugung und behandlung cardiovaskulärer erkrankungen
ATE255094T1 (de) Piperazinderivate zur behandlung der niedrigen harnwege
DE60026581D1 (de) Indolderivate zur behandlung von depression und angstzuständen
AU2251801A (en) Piperidine derivatives and their use as serotonin receptor antagonists
DE60131968D1 (de) PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN
ATE346040T1 (de) Aryl-sulfonamide als serotonin-antagonisten für de behandlung von fettleibigkeit
DE60213365D1 (de) Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen
DE60010934D1 (de) Medikamente geeignet zur Behandlung von proliferativen Erkrankungen
ATE374197T1 (de) Indolderivate zur behandlung von erkrankungen des zentralnervensystems
YU22802A (sh) Izonipekotamidi za lečenje poremećaja nastalih posredstvom integrina
DE60009315D1 (de) Verwendung von cyamemazin zur behandlung von entwöhnungserscheinungen der benzodiazepinbehandlung
JO2724B1 (en) 3-Alternative-5 -6-Amino Alkyl Indole-2-Carboxyl Acid Amide and Related Isotopes as Casein Kinase Inhibitors
DE60326348D1 (de) Makrozyclen zur behandlung von krebserkrankungen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties