ATE319998T1 - Zusammensetzungen und verfahren zur generierung roter chemilumineszenz - Google Patents
Zusammensetzungen und verfahren zur generierung roter chemilumineszenzInfo
- Publication number
- ATE319998T1 ATE319998T1 AT99309865T AT99309865T ATE319998T1 AT E319998 T1 ATE319998 T1 AT E319998T1 AT 99309865 T AT99309865 T AT 99309865T AT 99309865 T AT99309865 T AT 99309865T AT E319998 T1 ATE319998 T1 AT E319998T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- chemiluminescence
- luciferin
- compositions
- chemiluminescent
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical group OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 abstract 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 abstract 2
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- -1 cationic aromatic compound Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C07F9/6541—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1003—Carbocyclic compounds
- C09K2211/1007—Non-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/208,065 US5965736A (en) | 1996-01-16 | 1998-12-09 | Compositions and methods for generating red chemiluminescence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319998T1 true ATE319998T1 (de) | 2006-03-15 |
Family
ID=22773034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99309865T ATE319998T1 (de) | 1998-12-09 | 1999-12-08 | Zusammensetzungen und verfahren zur generierung roter chemilumineszenz |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5965736A (de) |
| EP (1) | EP1008600B1 (de) |
| JP (1) | JP4658281B2 (de) |
| AT (1) | ATE319998T1 (de) |
| AU (1) | AU767757C (de) |
| CA (1) | CA2292124A1 (de) |
| DE (1) | DE69930223T2 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965736A (en) * | 1996-01-16 | 1999-10-12 | Lumigen, Inc. | Compositions and methods for generating red chemiluminescence |
| AU716233B2 (en) * | 1996-01-16 | 2000-02-24 | Lumigen, Inc. | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes |
| US6783948B1 (en) * | 1999-07-30 | 2004-08-31 | Bayer Corporation | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes |
| US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| US8557868B2 (en) * | 2000-11-04 | 2013-10-15 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions using low molecular weight amines |
| US20060148665A1 (en) * | 2000-11-08 | 2006-07-06 | Bioconcept Laboratories | Ophthalmic and contact lens solutions containing forms of vitamin b |
| US20060127496A1 (en) * | 2000-11-08 | 2006-06-15 | Bioconcept Laboratories | L-histidine in ophthalmic solutions |
| US9308264B2 (en) | 2000-11-08 | 2016-04-12 | Fxs Ventures, Llc | Ophthalmic contact lens solutions containing forms of vitamin B |
| US20070104744A1 (en) * | 2000-11-08 | 2007-05-10 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions containing forms of vitamin b |
| JP4084997B2 (ja) * | 2000-11-08 | 2008-04-30 | エフエックスエス・ベンチャーズ・エルエルシー | 防腐剤増強剤として単純糖類を含有する改良眼科用およびコンタクトレンズ用溶液 |
| US9492582B2 (en) * | 2000-11-08 | 2016-11-15 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers |
| US20070110782A1 (en) * | 2000-11-08 | 2007-05-17 | Fxs Ventures, Llc | L-histidine in ophthalmic solutions |
| US20070098813A1 (en) * | 2000-11-08 | 2007-05-03 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions with a peroxide source and a preservative |
| DE60135572D1 (de) * | 2000-11-08 | 2008-10-09 | Fxs Ventures Llc | Verbesserte ophthalmologische und kontaktlinsenlösungen mit einer peroxidquelle und einem kationischen polymeren konservierungsmittel |
| US6867005B2 (en) | 2001-10-24 | 2005-03-15 | Beckman Coulter, Inc. | Method and apparatus for increasing the dynamic range and accuracy of binding assays |
| WO2004091438A2 (en) * | 2003-04-15 | 2004-10-28 | Fxs Ventures, Llc | Improved ophthalmic and contact lens solutions containing peptides as representative enhancers |
| WO2006116686A2 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanostructure enhanced luminescent devices |
| WO2006116687A2 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanoassays |
| WO2006116683A1 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanostructure enhanced luminescence |
| CN101154447B (zh) * | 2006-09-28 | 2010-08-18 | 北京握奇数据系统有限公司 | 一种闪存控制方法及闪存 |
| WO2009142678A1 (en) * | 2008-03-27 | 2009-11-26 | Promega Corporatin | Protein labeling with cyanobenzothiazole conjugates |
| SG11201811579VA (en) | 2016-06-30 | 2019-01-30 | Beckman Coulter Inc | Chemiluminescent substrates |
| JP7104702B2 (ja) | 2016-12-01 | 2022-07-21 | プロメガ コーポレイション | ５，５－二置換ルシフェリン及びルシフェラーゼ系アッセイにおけるそれらの使用 |
| CN109490281A (zh) * | 2018-10-18 | 2019-03-19 | 深圳天深医疗器械有限公司 | 化学发光底物液及其应用 |
| US12625077B2 (en) | 2020-08-14 | 2026-05-12 | Ohio Northern University | Fluorosurfactant detection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629168A (en) * | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
| US5965736A (en) * | 1996-01-16 | 1999-10-12 | Lumigen, Inc. | Compositions and methods for generating red chemiluminescence |
| AU716233B2 (en) * | 1996-01-16 | 2000-02-24 | Lumigen, Inc. | Compounds, compositions and methods for generating chemiluminescence with phosphatase enzymes |
-
1998
- 1998-12-09 US US09/208,065 patent/US5965736A/en not_active Expired - Lifetime
-
1999
- 1999-11-30 AU AU61779/99A patent/AU767757C/en not_active Expired
- 1999-12-08 DE DE69930223T patent/DE69930223T2/de not_active Expired - Lifetime
- 1999-12-08 CA CA002292124A patent/CA2292124A1/en not_active Abandoned
- 1999-12-08 JP JP34939699A patent/JP4658281B2/ja not_active Expired - Lifetime
- 1999-12-08 EP EP99309865A patent/EP1008600B1/de not_active Expired - Lifetime
- 1999-12-08 AT AT99309865T patent/ATE319998T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000169459A (ja) | 2000-06-20 |
| JP4658281B2 (ja) | 2011-03-23 |
| CA2292124A1 (en) | 2000-06-09 |
| AU767757C (en) | 2004-06-17 |
| AU6177999A (en) | 2000-06-15 |
| US5965736A (en) | 1999-10-12 |
| EP1008600A3 (de) | 2002-02-27 |
| DE69930223T2 (de) | 2006-12-07 |
| EP1008600A2 (de) | 2000-06-14 |
| AU767757B2 (en) | 2003-11-20 |
| EP1008600B1 (de) | 2006-03-08 |
| DE69930223D1 (de) | 2006-05-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69930223D1 (de) | Zusammensetzungen und Verfahren zur Generierung roter Chemilumineszenz | |
| ATE236177T1 (de) | Verbindungen, zusammensetzungen und methoden zur erzeugung von chemilumineszenz mit phosphatase- enzymen | |
| DE69823845D1 (de) | Neue verbindungen zur erzeugung von chemilumineszenz mit hilfe einer peroxidase | |
| GR3036391T3 (en) | Use of exonuclease and/or glycosylase as supplements to anti-polymerase antibody to increase specificity in polymerase chain reaction | |
| ATE443136T1 (de) | Methode für dna synthese | |
| ATE537264T1 (de) | Verfahren und zusammensetzungen für die gerichtete mikrowellenchemiie | |
| AU2002359522A1 (en) | Compositions and methods of selective nucleic acid isolation | |
| EP1019525A4 (de) | Chemilumineszierende zusammensetzungen und entsprechende verfahren | |
| DE69732098D1 (de) | Verbindungen mit sulfonsäure-amidgruppe | |
| DE69829722D1 (de) | Verfahren zur Herstellung von Katalysatoren zur Verwendung in Umwandlungsreaktionen von organischen Verbindungen | |
| ES2185218T3 (es) | Un plasma sanguineo aplicable universalmente. | |
| DE69823662D1 (de) | 1,4,7,10-tetraazabicyclo(8.2.2)tetradecan-2-on, verfahren zu ihrer herstellung und ihrer verwendung für die herstellung von tetraazamacrocyclen | |
| ATE199709T1 (de) | Verfahren zur herstellung von (+)compactin und (+)mevinolin derivaten mit beta-hydroxy-delta- lactonresten | |
| EP1156122A3 (de) | Ein Fluoreszenzpolarisierung-Testverfahren | |
| ATE319690T1 (de) | Verfahren und synthesezwischenprodukte zur herstellung von n-arylacridancarbonsäurederivaten | |
| DK150549C (da) | Katalysator til biokemiske omdannelsesreaktioner med samtidigt immobiliserede enzymer og mikroorganismer samt fremgangsmaade til fremstilling heraf | |
| AU4707793A (en) | Ptp-d subfamily of protein tyrosine phosphatases | |
| ATE77380T1 (de) | Zwischenprodukte fuer die produktion von podophyllotoxin und verwandte verbindungen und verfahren zu deren herstellung und deren verwendung. | |
| DE69817282D1 (de) | Neue Katalysatoren für die Umwandlungsreaktionen von organischen Verbindungen | |
| DE69835834D1 (de) | Chemielumineszierende reaktionen unter verwendung von dihydroxylierten aromaten und heterocyclischen enolphosphaten | |
| EP0219352A3 (de) | Chemilumineszenzverfahren und -besteck | |
| ATE199559T1 (de) | N- und o-substituierte aminophenolderivate, zwischenprodukte zu deren herstellung, deren verwendung als hydrolasesubstrate, ein entsprechendes bestimmungsverfahren und hierfür geeignetes diagnostisches mittel | |
| DE60231645D1 (de) | Verbesserte verbindungen für die erzeugung von chemilumineszenz mit einer peroxidase | |
| BR0108273A (pt) | Preparação de flavonóides monoglicosidados | |
| WO2001025246A3 (en) | Chromogenic substrates of sialidase of bacterial, viral, protozoa, and vertebrate origin and methods of making and using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |