ATE320417T1 - Naphthimidobenzamid-derivate - Google Patents
Naphthimidobenzamid-derivateInfo
- Publication number
- ATE320417T1 ATE320417T1 AT99926895T AT99926895T ATE320417T1 AT E320417 T1 ATE320417 T1 AT E320417T1 AT 99926895 T AT99926895 T AT 99926895T AT 99926895 T AT99926895 T AT 99926895T AT E320417 T1 ATE320417 T1 AT E320417T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen atom
- different
- same
- independently represents
- naphthimidobenzamide
- Prior art date
Links
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18907898 | 1998-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE320417T1 true ATE320417T1 (de) | 2006-04-15 |
Family
ID=16234950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926895T ATE320417T1 (de) | 1998-07-03 | 1999-07-02 | Naphthimidobenzamid-derivate |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6300331B1 (de) |
| EP (1) | EP1020446B1 (de) |
| JP (1) | JP3357662B2 (de) |
| KR (1) | KR100364205B1 (de) |
| AT (1) | ATE320417T1 (de) |
| AU (1) | AU727591B2 (de) |
| CA (1) | CA2300069C (de) |
| DE (1) | DE69930383T2 (de) |
| WO (1) | WO2000001672A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU728523C (en) * | 1996-10-21 | 2001-08-09 | Nps Pharmaceuticals, Inc. | Neurotrophin antagonist compositions |
| AU2005201951C1 (en) * | 1999-05-17 | 2009-07-16 | Queen's University | Method of inhibiting neurotrophin-receptor binding |
| US6492380B1 (en) * | 1999-05-17 | 2002-12-10 | Queen's University At Kingston | Method of inhibiting neurotrophin-receptor binding |
| US6468990B1 (en) * | 1999-05-17 | 2002-10-22 | Queen's University At Kingston | Method of inhibiting binding of nerve growth factor to p75 NTR receptor |
| WO2007030939A2 (en) | 2005-09-15 | 2007-03-22 | Painceptor Pharma Corporation | Methods of modulating neurotrophin-mediated activity |
| EP2050747A1 (de) * | 2007-10-12 | 2009-04-22 | BioAlliance Pharma | Harmol- bzw. Harmolderivat-Dimere und deren Verwendung |
| WO2009089537A2 (en) * | 2008-01-11 | 2009-07-16 | Northwestern University | Anti-cancer compounds |
| US8288387B2 (en) * | 2008-03-05 | 2012-10-16 | Council Of Scientific & Industrial Research | Napthalimide-benzimidazole hybrids as potential antitumor agents and process for the preparation thereof |
| JP5834390B2 (ja) * | 2010-10-05 | 2015-12-24 | 東レ・ファインケミカル株式会社 | ジアシル誘導体の製造方法 |
| JP2012077045A (ja) * | 2010-10-05 | 2012-04-19 | Toray Fine Chemicals Co Ltd | 高純度ジアシル誘導体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3481120D1 (de) | 1983-04-01 | 1990-03-01 | Warner Lambert Co | 3,6-disubstituierte-1,8-naphthalimide, verfahren zu ihrer herstellung und ihre verwendung. |
| DE3942280A1 (de) * | 1989-12-21 | 1991-06-27 | Knoll Ag | N-substituierte naphthalimide, ihre herstellung und verwendung |
| US5086059A (en) * | 1990-06-07 | 1992-02-04 | Du Pont Merck Pharmaceutical Company | Bis-naphthalimides as anticancer agents |
| US5206249A (en) * | 1991-03-27 | 1993-04-27 | Du Pont Merck Pharmaceutical Company | Bis-naphthalimides containing amino-acid derived linkers as anticancer agents |
| JPH07501822A (ja) | 1991-12-11 | 1995-02-23 | デュポン・ファーマシュウティカルズ・カンパニー | 抗癌剤として有用な高度に水溶性のビス−ナフタルイミド |
-
1999
- 1999-07-02 EP EP99926895A patent/EP1020446B1/de not_active Expired - Lifetime
- 1999-07-02 KR KR20007002109A patent/KR100364205B1/ko not_active Expired - Fee Related
- 1999-07-02 CA CA002300069A patent/CA2300069C/en not_active Expired - Fee Related
- 1999-07-02 US US09/508,044 patent/US6300331B1/en not_active Expired - Fee Related
- 1999-07-02 AT AT99926895T patent/ATE320417T1/de not_active IP Right Cessation
- 1999-07-02 DE DE69930383T patent/DE69930383T2/de not_active Expired - Fee Related
- 1999-07-02 JP JP2000558077A patent/JP3357662B2/ja not_active Expired - Fee Related
- 1999-07-02 AU AU43963/99A patent/AU727591B2/en not_active Ceased
- 1999-07-02 WO PCT/JP1999/003574 patent/WO2000001672A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1020446B1 (de) | 2006-03-15 |
| CA2300069C (en) | 2006-01-17 |
| EP1020446A1 (de) | 2000-07-19 |
| KR100364205B1 (ko) | 2002-12-11 |
| CA2300069A1 (en) | 2000-01-13 |
| DE69930383D1 (de) | 2006-05-11 |
| DE69930383T2 (de) | 2006-10-05 |
| AU727591B2 (en) | 2000-12-14 |
| WO2000001672A1 (en) | 2000-01-13 |
| JP3357662B2 (ja) | 2002-12-16 |
| KR20010023464A (ko) | 2001-03-26 |
| EP1020446A4 (de) | 2001-11-07 |
| AU4396399A (en) | 2000-01-24 |
| US6300331B1 (en) | 2001-10-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |