ATE321886T1 - Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe - Google Patents
Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probeInfo
- Publication number
- ATE321886T1 ATE321886T1 AT00979904T AT00979904T ATE321886T1 AT E321886 T1 ATE321886 T1 AT E321886T1 AT 00979904 T AT00979904 T AT 00979904T AT 00979904 T AT00979904 T AT 00979904T AT E321886 T1 ATE321886 T1 AT E321886T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- nucleic acid
- oligonucleotides
- absence
- detecting
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44954599A | 1999-11-29 | 1999-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321886T1 true ATE321886T1 (de) | 2006-04-15 |
Family
ID=23784560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00979904T ATE321886T1 (de) | 1999-11-29 | 2000-11-29 | Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6887662B1 (de) |
| EP (1) | EP1250451B1 (de) |
| JP (1) | JP2004512813A (de) |
| AT (1) | ATE321886T1 (de) |
| AU (1) | AU1728001A (de) |
| BR (1) | BR0016105A (de) |
| CA (1) | CA2392469A1 (de) |
| DE (1) | DE60027045T2 (de) |
| ES (1) | ES2256067T3 (de) |
| IL (1) | IL149791A0 (de) |
| WO (1) | WO2001038570A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833779B2 (en) * | 2001-07-25 | 2010-11-16 | Jivan Biologies Inc. | Methods and systems for polynucleotide detection |
| US7340349B2 (en) * | 2001-07-25 | 2008-03-04 | Jonathan Bingham | Method and system for identifying splice variants of a gene |
| US20050017981A1 (en) * | 2003-03-17 | 2005-01-27 | Jonathan Bingham | Methods of representing gene product sequences and expression |
| US9012142B2 (en) * | 2005-02-15 | 2015-04-21 | Georgetown University | Sequence-specific detection of nucleotide sequences |
| WO2010096202A2 (en) | 2009-02-23 | 2010-08-26 | Georgetown University | Sequence-specific detection of nucleotide sequences |
| US20070026423A1 (en) * | 2005-03-16 | 2007-02-01 | Thomas Koehler | Method and test kit for the detection of target nucleic acids |
| EP1910397A4 (de) | 2005-07-15 | 2009-07-01 | Applera Corp | Entwurf einer heissstart-rückübertragung durch primer |
| US20070048764A1 (en) * | 2005-08-23 | 2007-03-01 | Jonathan Bingham | Indicator polynucleotide controls |
| NZ548731A (en) * | 2006-07-24 | 2008-12-24 | Zygem Corp Ltd | Isothermal detection methods and uses thereof |
| US8017104B2 (en) * | 2007-02-28 | 2011-09-13 | Carestream Health, Inc. | Large stoke shift dye used for optical imaging |
| US8906354B2 (en) | 2007-02-28 | 2014-12-09 | Bruker Biospin Corporation | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes |
| US20110207132A1 (en) * | 2008-08-04 | 2011-08-25 | University Of Maryland | Probes and methods for detecting analytes |
| JP6147502B2 (ja) * | 2009-10-27 | 2017-06-14 | スウィフト バイオサイエンシーズ, インコーポレイテッド | ポリヌクレオチドプライマー及びプローブ |
| EP2504453A4 (de) * | 2009-11-23 | 2013-07-17 | Becton Dickinson Co | Assayverfahren für zielnukleinsäuren durch signalverstärkung mit sondenhybridisierung und -beschränkung |
| US10947588B2 (en) | 2014-06-19 | 2021-03-16 | Multiplicom N.V. | Restriction mediated quantitative polymerase chain reactions |
| EP3307911B1 (de) * | 2015-06-11 | 2020-12-09 | Bio-Rad Laboratories, Inc. | Amplifikationsverfahren mit einem sondenkonkurrent |
| WO2018237088A1 (en) | 2017-06-20 | 2018-12-27 | Bio-Rad Laboratories, Inc. | DIGITAL AMPLIFICATION ASSAYS FOR GENETIC INSTABILITY |
| CN110951919B (zh) * | 2019-12-24 | 2023-09-26 | 圣湘生物科技股份有限公司 | 一种用于检测的寡核苷酸、试剂盒以及使用其的检测方法 |
| WO2024102958A1 (en) * | 2022-11-11 | 2024-05-16 | Biomeme, Inc. | Methods and compositions for processing and amplification of nucleic acids |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5118801A (en) * | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| US5849481A (en) * | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
| US6197556B1 (en) * | 1991-12-20 | 2001-03-06 | The University Of Chicago | Nucleic acid amplification using modular branched primers |
| US5424413A (en) * | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5830658A (en) * | 1995-05-31 | 1998-11-03 | Lynx Therapeutics, Inc. | Convergent synthesis of branched and multiply connected macromolecular structures |
| US6136533A (en) * | 1997-07-03 | 2000-10-24 | Id Biomedical | Additives for use in cycling probe reactions |
| WO1999042616A1 (en) * | 1998-02-20 | 1999-08-26 | Dade Behring Inc. | Methods for determining concentrations of nucleic acids |
| US6203989B1 (en) * | 1998-09-30 | 2001-03-20 | Affymetrix, Inc. | Methods and compositions for amplifying detectable signals in specific binding assays |
-
2000
- 2000-11-29 CA CA002392469A patent/CA2392469A1/en not_active Abandoned
- 2000-11-29 BR BR0016105-5A patent/BR0016105A/pt not_active Application Discontinuation
- 2000-11-29 EP EP00979904A patent/EP1250451B1/de not_active Expired - Lifetime
- 2000-11-29 JP JP2001539912A patent/JP2004512813A/ja active Pending
- 2000-11-29 WO PCT/IL2000/000798 patent/WO2001038570A1/en not_active Ceased
- 2000-11-29 AU AU17280/01A patent/AU1728001A/en not_active Abandoned
- 2000-11-29 ES ES00979904T patent/ES2256067T3/es not_active Expired - Lifetime
- 2000-11-29 DE DE60027045T patent/DE60027045T2/de not_active Expired - Fee Related
- 2000-11-29 IL IL14979100A patent/IL149791A0/xx unknown
- 2000-11-29 AT AT00979904T patent/ATE321886T1/de not_active IP Right Cessation
- 2000-12-04 US US09/727,480 patent/US6887662B1/en not_active Expired - Lifetime
-
2003
- 2003-12-29 US US10/745,509 patent/US20040142369A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60027045T2 (de) | 2006-10-19 |
| CA2392469A1 (en) | 2001-05-31 |
| JP2004512813A (ja) | 2004-04-30 |
| ES2256067T3 (es) | 2006-07-16 |
| EP1250451A4 (de) | 2004-07-14 |
| IL149791A0 (en) | 2002-11-10 |
| AU1728001A (en) | 2001-06-04 |
| BR0016105A (pt) | 2002-08-20 |
| EP1250451B1 (de) | 2006-03-29 |
| EP1250451A1 (de) | 2002-10-23 |
| DE60027045D1 (de) | 2006-05-18 |
| US20040142369A1 (en) | 2004-07-22 |
| US6887662B1 (en) | 2005-05-03 |
| WO2001038570A1 (en) | 2001-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |