ATE322895T1 - Coenzym q10 zur behandlung von erkrankungen der augen - Google Patents

Coenzym q10 zur behandlung von erkrankungen der augen

Info

Publication number: ATE322895T1
Authority: AT; Austria
Prior art keywords: coenzyme; treatment; eye diseases; pathologies; degenerative
Prior art date: 2001-12-20

Application number

AT02425777T

Other languages

English (en)

Inventor

Rosario Brancato

Giorgio Lenaz

Sergio Capaccioli

Nicola Schiavone

Original Assignee

Simonelli Giuseppe

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-20

Filing date

2002-12-17

Publication date

2006-04-15

2002-12-17 Application filed by Simonelli Giuseppe filed Critical Simonelli Giuseppe

2006-04-15 Application granted granted Critical

2006-04-15 Publication of ATE322895T1 publication Critical patent/ATE322895T1/de

Links

ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 2
208000030533 eye disease Diseases 0.000 title 1
230000003412 degenerative effect Effects 0.000 abstract 2
ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 abstract 1
206010021143 Hypoxia Diseases 0.000 abstract 1
230000001640 apoptogenic effect Effects 0.000 abstract 1
235000017471 coenzyme Q10 Nutrition 0.000 abstract 1
229940110767 coenzyme Q10 Drugs 0.000 abstract 1
230000001627 detrimental effect Effects 0.000 abstract 1
230000007954 hypoxia Effects 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
208000028867 ischemia Diseases 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000008397 ocular pathology Effects 0.000 abstract 1
230000007170 pathology Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
238000007910 systemic administration Methods 0.000 abstract 1
238000011200 topical administration Methods 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1
230000001228 trophic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT02425777T 2001-12-20 2002-12-17 Coenzym q10 zur behandlung von erkrankungen der augen ATE322895T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2001RM000755A ITRM20010755A1 (it)	2001-12-20	2001-12-20	Uso del chinone q10 per il trattamento delle malattie oculari.

Publications (1)

Publication Number	Publication Date
ATE322895T1 true ATE322895T1 (de)	2006-04-15

Family

ID=11455922

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02425777T ATE322895T1 (de)	2001-12-20	2002-12-17	Coenzym q10 zur behandlung von erkrankungen der augen

Country Status (6)

Country	Link
US (1)	US7029672B2 (de)
EP (1)	EP1321138B1 (de)
AT (1)	ATE322895T1 (de)
DE (1)	DE60210568T2 (de)
ES (1)	ES2262777T3 (de)
IT (1)	ITRM20010755A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITRM20030153A1 (it) *	2003-04-03	2004-10-04	Exall S R L	Formulazione idrosolubile contenente ubichinone per uso oftalmico.
ES2410587T3 (es)	2004-01-22	2013-07-02	University Of Miami	Formulaciones tópicas de coenzima Q10 y métodos de uso
US20060127384A1 (en) *	2004-12-09	2006-06-15	Sergio Capaccioli	Coenzyme Q10 as antiapoptotic agent
EP2095713A1 (de)	2006-10-20	2009-09-02	Limited Liability Company "Mitotechnology"	Zusammensetzung für die regeneration und stimulation des wachstums von pflanzen und für die anpassung von pflanzen an unterschiedliche stressfaktoren
EP2119436A4 (de) *	2006-10-20	2010-03-03	Ltd Liability Company Mitotech	Pharmazeutische zusammensetzungen zur verhinderung und behandlung von augenkrankheiten
EA200901061A1 (ru)	2007-01-29	2009-12-30	Общество С Ограниченной Ответственностью "Митотехнология"	Фармацевтические и косметические композиции для ускорения процесса заживления ран и других поверхностных повреждений
US8349902B2 (en)	2007-01-29	2013-01-08	Mitotech Sa	Pharmaceutical compositions useful for preventing and treating oncological diseases
MX337408B (es)	2007-03-22	2016-03-03	Berg Llc	Formulaciones topicas que tienen biodisponibilidad aumentada.
WO2008127138A1 (fr)	2007-04-11	2008-10-23	Limited Liability Company 'mitotechnology'	Composition visant à ralentir le vieillissement et à allonger la durée de vie de l'organisme et utilisation de cette composition
WO2008133198A1 (ja) *	2007-04-20	2008-11-06	Senju Pharmaceutical Co., Ltd.	神経突起形成促進剤
US8518915B2 (en)	2007-06-29	2013-08-27	Mitotech Sa	Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases
WO2009126764A1 (en)	2008-04-11	2009-10-15	Cytotech Labs, Llc	Methods and use of inducing apoptosis in cancer cells
WO2010056145A1 (ru)	2008-11-12	2010-05-20	Общество С Ограниченной Ответственностью "Митотехнология"	Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов
EA023913B1 (ru)	2009-05-11	2016-07-29	БЕРГ ФАРМА ЭлЭлСи	Способы лечения метаболических нарушений, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния
CN102548548B (zh)	2009-06-10	2017-09-01	米拓科技有限公司（卢森堡）	用于医学和兽医学的眼科药物组合物
CN102791670A (zh)	2009-11-13	2012-11-21	米拓科技有限责任公司	基于定向于线粒体的抗氧化剂的药物物质
KR101907411B1 (ko) *	2010-03-12	2018-10-12	베르그 엘엘씨	코엔자임 Ｑ10(ＣｏＱ10)의 정맥내 제형 및 이의 사용 방법
CN103608323B (zh)	2011-04-04	2016-08-17	博格有限责任公司	治疗中枢神经系统肿瘤的方法
WO2012167236A1 (en)	2011-06-03	2012-12-06	Mitotech Sa	Oral formulations of mitochondrially-targeted antioxidants and their preparation and use
CN107095863A (zh)	2011-06-17	2017-08-29	博格有限责任公司	可吸入药物组合物
EP2983654B1 (de)	2013-04-08	2025-11-12	BPGbio, Inc.	Behandlung von krebs mit coenzym-q10-kombinationstherapien
WO2015035094A1 (en)	2013-09-04	2015-03-12	Berg Llc	Methods of treatment of cancer by continuous infusion of coenzyme q10
US20170189350A1 (en)	2015-11-16	2017-07-06	Berg Llc	Methods of treatment of temozolomide-resistant glioma using coenzyme q10

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US119936A (en) *		1871-10-17		Improvement in fire-extinguishers
FR2608045B1 (fr) *	1986-12-12	1990-03-02	Chauvin Laboratoires	Utilisation d'inhibiteurs de xanthine- oxydase, de piegeurs de radicaux libres oxygenes et de chelateurs du fer pour la fabrication d'une composition pharmaceutique destinee au traitement du glaucome et compositions pharmaceutiques destinees au traitement du glaucome
AU4510596A (en) *	1994-12-06	1996-06-26	National Research Council Of Canada	Water soluble ubiquinone compositions, prodrugs, and methods relating thereto
US20020032160A1 (en)	1995-02-24	2002-03-14	Nyce Jonathan W.	Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels
IT1299578B1 (it) *	1998-07-24	2000-03-16	Rosario Brancato	Uso dell'ubichinone per la produzione di un farmaco efficace nella prevenzione e nel trattamento della degenerazione maculare correlata
IT1304406B1 (it)	1998-10-21	2001-03-19	Danital Italia S R L	Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3.
WO2000057871A2 (en) *	1999-03-30	2000-10-05	Purdue Research Foundation	Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof
IT1307281B1 (it) *	1999-11-25	2001-10-30	Simonelli Giuseppe	Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,
US6441050B1 (en)	2000-08-29	2002-08-27	Raj K. Chopra	Palatable oral coenzyme Q liquid
US6403116B1 (en)	2000-11-03	2002-06-11	Triarco Inductries, Inc.	Coenzyme Q10 formulation

2001
- 2001-12-20 IT IT2001RM000755A patent/ITRM20010755A1/it unknown
2002
- 2002-12-17 DE DE60210568T patent/DE60210568T2/de not_active Expired - Fee Related
- 2002-12-17 ES ES02425777T patent/ES2262777T3/es not_active Expired - Lifetime
- 2002-12-17 EP EP02425777A patent/EP1321138B1/de not_active Expired - Lifetime
- 2002-12-17 AT AT02425777T patent/ATE322895T1/de not_active IP Right Cessation
- 2002-12-20 US US10/323,820 patent/US7029672B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7029672B2 (en)	2006-04-18
ES2262777T3 (es)	2006-12-01
EP1321138A1 (de)	2003-06-25
US20030118576A1 (en)	2003-06-26
EP1321138B1 (de)	2006-04-12
DE60210568T2 (de)	2007-05-24
DE60210568D1 (de)	2006-05-24
ITRM20010755A1 (it)	2003-06-20

Legal Events

Date	Code	Title	Description
2006-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60210568D1 (de)	2006-05-24	Coenzym Q10 zur Behandlung von Erkrankungen der Augen
IS7215A (is)	2004-04-07	Aðferðir til að meðhöndla nýæðarsjúkdóma í augum
MXPA04006184A (es)	2004-12-06	Compuestos derivados de 1h-pirazolilo, para el uso en enfermedades asociadas con el receptor 5-ht2c.
CY1108514T1 (el)	2014-04-09	Παραγωγα 1-φαινυλαλκανεκαρβοξυλικου οξεος για τη θεραπεια νευρογενων ασθενειων
MY135841A (en)	2008-07-31	Novel benzodioxoles
CY1107956T1 (el)	2013-03-13	Χρηση υποκατεστημενων 2-αμινοτετραλινιων για την προληπτικη αντιμετωπιση της νοσου του παρκινσον
ATE361288T1 (de)	2007-05-15	N-(3,-dimethylindolin-6-yl)ä2-ä(4-
EA200601223A1 (ru)	2006-12-29	Производные сульфонамида для лечения заболеваний
EA200601141A1 (ru)	2007-02-27	Сульфонамидные производные для лечения заболеваний
MY144483A (en)	2011-09-30	1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases
BR0211972A (pt)	2004-09-21	Composição oftálmica
MXPA05009535A (es)	2005-11-16	Compuestos de acido n - alquil - hidroxamico - isoindolilo y sus usos farmaceuticos.
EA200801711A1 (ru)	2008-12-30	Пролекарства возбуждающих аминокислот
TW200502221A (en)	2005-01-16	Novel lactams and uses thereof
EA200600071A1 (ru)	2006-08-25	Производные n-фенилпиперазина и способы профилактики или лечения заболеваний, связанных с 5ht-рецептором
MXPA05007115A (es)	2005-11-16	Nuevos agonistas inversos del receptor cb 1.
TW200505865A (en)	2005-02-16	Compounds useful for the treatment of diseases
WO2023246870A9 (zh)	2024-02-29	吲哚化合物的制备、应用及用途
ATE491453T1 (de)	2011-01-15	Verwendung von 4-aminochinolin-verbindungen zur behandlung entzündlicher erkrankungen des auges
WO2005075450A3 (en)	2006-03-30	Spiro-benzodioxoles and their use as cb1 antagonists
ECSP055844A (es)	2005-09-20	Nuevos compuestos triciclicos
WO2020165838A9 (en)	2021-03-18	Methods for treating ocular surface pain
CA2534634A1 (en)	2005-04-14	Azolidinecarbonitriles and their use as dpp-iv inhibitors
ATE464048T1 (de)	2010-04-15	Behandlung von alzheimer-krankheit und verwandten zuständen
EA200201232A1 (ru)	2003-04-24	Производные сульфонамида