ATE322895T1 - Coenzym q10 zur behandlung von erkrankungen der augen - Google Patents
Coenzym q10 zur behandlung von erkrankungen der augenInfo
- Publication number
- ATE322895T1 ATE322895T1 AT02425777T AT02425777T ATE322895T1 AT E322895 T1 ATE322895 T1 AT E322895T1 AT 02425777 T AT02425777 T AT 02425777T AT 02425777 T AT02425777 T AT 02425777T AT E322895 T1 ATE322895 T1 AT E322895T1
- Authority
- AT
- Austria
- Prior art keywords
- coenzyme
- treatment
- eye diseases
- pathologies
- degenerative
- Prior art date
Links
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 2
- 208000030533 eye disease Diseases 0.000 title 1
- 230000003412 degenerative effect Effects 0.000 abstract 2
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 230000001640 apoptogenic effect Effects 0.000 abstract 1
- 235000017471 coenzyme Q10 Nutrition 0.000 abstract 1
- 229940110767 coenzyme Q10 Drugs 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 230000007954 hypoxia Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000008397 ocular pathology Effects 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000007910 systemic administration Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001RM000755A ITRM20010755A1 (it) | 2001-12-20 | 2001-12-20 | Uso del chinone q10 per il trattamento delle malattie oculari. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322895T1 true ATE322895T1 (de) | 2006-04-15 |
Family
ID=11455922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02425777T ATE322895T1 (de) | 2001-12-20 | 2002-12-17 | Coenzym q10 zur behandlung von erkrankungen der augen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7029672B2 (de) |
| EP (1) | EP1321138B1 (de) |
| AT (1) | ATE322895T1 (de) |
| DE (1) | DE60210568T2 (de) |
| ES (1) | ES2262777T3 (de) |
| IT (1) | ITRM20010755A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20030153A1 (it) * | 2003-04-03 | 2004-10-04 | Exall S R L | Formulazione idrosolubile contenente ubichinone per uso oftalmico. |
| KR101395370B1 (ko) | 2004-01-22 | 2014-05-14 | 유니버시티 오브 마이애미 | 국소용 코-엔자임 큐10 제형 및 그의 사용 방법 |
| US20060127384A1 (en) * | 2004-12-09 | 2006-06-15 | Sergio Capaccioli | Coenzyme Q10 as antiapoptotic agent |
| EA200900583A1 (ru) | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Композиция для регенерации, стимуляции роста и адаптации растений к различным стрессовым факторам |
| EA200900582A1 (ru) * | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Фармацевтические композиции для профилактики и лечения глазных патологий |
| EP2145623A4 (de) | 2007-01-29 | 2010-10-27 | Ltd Liability Company Mitotech | Pharmazeutische und kosmetische zusammensetzungen zur beschleunigten heilung von wunden und anderen oberflächenschäden |
| WO2008094062A1 (en) | 2007-01-29 | 2008-08-07 | Limited Liability Company 'mitotechnology' | Pharmaceutical compositions useful for preventing and treating oncological diseases |
| MX337408B (es) | 2007-03-22 | 2016-03-03 | Berg Llc | Formulaciones topicas que tienen biodisponibilidad aumentada. |
| WO2008127138A1 (fr) | 2007-04-11 | 2008-10-23 | Limited Liability Company 'mitotechnology' | Composition visant à ralentir le vieillissement et à allonger la durée de vie de l'organisme et utilisation de cette composition |
| KR101486605B1 (ko) * | 2007-04-20 | 2015-01-26 | 센주 세이야꾸 가부시키가이샤 | 신경돌기 형성 촉진제 |
| WO2009005386A1 (en) | 2007-06-29 | 2009-01-08 | Limited Liability Company 'mitotechnology' | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases |
| MX2010011032A (es) | 2008-04-11 | 2011-03-01 | Cytotech Labs Llc Star | Metodos y uso de induccion de apoptosis en celulas cancerigenas. |
| WO2010056145A1 (ru) | 2008-11-12 | 2010-05-20 | Общество С Ограниченной Ответственностью "Митотехнология" | Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов |
| CN102481271A (zh) | 2009-05-11 | 2012-05-30 | 博格生物系统有限责任公司 | 利用表观代谢转变剂、多维细胞内分子或环境影响剂治疗代谢障碍的方法 |
| AU2009347921B8 (en) | 2009-06-10 | 2014-07-24 | Mitotech Sa | Pharmaceutical composition for use in medical and veterinary ophthalmology |
| BR112012011197A2 (pt) | 2009-11-13 | 2020-10-20 | Obschestvo S Ogranichennoi Otvetsvennostyu "Mitotekh" | subtâncias farmacêuticas com base em antioxidantes direcionados à mitocôndria |
| SG10202010355PA (en) * | 2010-03-12 | 2020-11-27 | Berg Llc | Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof |
| CA2832324C (en) | 2011-04-04 | 2022-03-15 | Berg Llc | Methods of treating central nervous system tumors |
| EP2714024B1 (de) | 2011-06-03 | 2018-10-03 | Mitotech SA | Orale formulierungen aus auf mitochondrien gerichteten antioxidantien sowie herstellung und verwendung davon |
| EP2720680B1 (de) | 2011-06-17 | 2020-02-12 | Berg LLC | Inhalbierbare pharmazeutische zusammensetzungen |
| NZ713868A (en) | 2013-04-08 | 2021-12-24 | Berg Llc | Treatment of cancer using coenzyme q10 combination therapies |
| KR102370843B1 (ko) | 2013-09-04 | 2022-03-04 | 버그 엘엘씨 | 코엔자임 q10의 연속주입에 의한 암치료 방법 |
| WO2017087576A1 (en) | 2015-11-16 | 2017-05-26 | Berg Llc | Methods of treatment of temozolomide-resistant glioma using coenzyme q10 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US119936A (en) * | 1871-10-17 | Improvement in fire-extinguishers | ||
| FR2608045B1 (fr) * | 1986-12-12 | 1990-03-02 | Chauvin Laboratoires | Utilisation d'inhibiteurs de xanthine- oxydase, de piegeurs de radicaux libres oxygenes et de chelateurs du fer pour la fabrication d'une composition pharmaceutique destinee au traitement du glaucome et compositions pharmaceutiques destinees au traitement du glaucome |
| CA2207093A1 (en) * | 1994-12-06 | 1996-06-13 | National Research Council Of Canada | Water soluble ubiquinone compositions, prodrugs, and methods relating thereto |
| US20020032160A1 (en) | 1995-02-24 | 2002-03-14 | Nyce Jonathan W. | Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels |
| IT1299578B1 (it) * | 1998-07-24 | 2000-03-16 | Rosario Brancato | Uso dell'ubichinone per la produzione di un farmaco efficace nella prevenzione e nel trattamento della degenerazione maculare correlata |
| IT1304406B1 (it) * | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| WO2000057871A2 (en) * | 1999-03-30 | 2000-10-05 | Purdue Research Foundation | Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof |
| IT1307281B1 (it) * | 1999-11-25 | 2001-10-30 | Simonelli Giuseppe | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
| US6441050B1 (en) * | 2000-08-29 | 2002-08-27 | Raj K. Chopra | Palatable oral coenzyme Q liquid |
| US6403116B1 (en) * | 2000-11-03 | 2002-06-11 | Triarco Inductries, Inc. | Coenzyme Q10 formulation |
-
2001
- 2001-12-20 IT IT2001RM000755A patent/ITRM20010755A1/it unknown
-
2002
- 2002-12-17 DE DE60210568T patent/DE60210568T2/de not_active Expired - Fee Related
- 2002-12-17 AT AT02425777T patent/ATE322895T1/de not_active IP Right Cessation
- 2002-12-17 EP EP02425777A patent/EP1321138B1/de not_active Expired - Lifetime
- 2002-12-17 ES ES02425777T patent/ES2262777T3/es not_active Expired - Lifetime
- 2002-12-20 US US10/323,820 patent/US7029672B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1321138A1 (de) | 2003-06-25 |
| ITRM20010755A1 (it) | 2003-06-20 |
| EP1321138B1 (de) | 2006-04-12 |
| US20030118576A1 (en) | 2003-06-26 |
| ES2262777T3 (es) | 2006-12-01 |
| US7029672B2 (en) | 2006-04-18 |
| DE60210568T2 (de) | 2007-05-24 |
| DE60210568D1 (de) | 2006-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE322895T1 (de) | Coenzym q10 zur behandlung von erkrankungen der augen | |
| IS7215A (is) | Aðferðir til að meðhöndla nýæðarsjúkdóma í augum | |
| MXPA04006184A (es) | Compuestos derivados de 1h-pirazolilo, para el uso en enfermedades asociadas con el receptor 5-ht2c. | |
| CY1108514T1 (el) | Παραγωγα 1-φαινυλαλκανεκαρβοξυλικου οξεος για τη θεραπεια νευρογενων ασθενειων | |
| MY135841A (en) | Novel benzodioxoles | |
| CY1107956T1 (el) | Χρηση υποκατεστημενων 2-αμινοτετραλινιων για την προληπτικη αντιμετωπιση της νοσου του παρκινσον | |
| ATE361288T1 (de) | N-(3,-dimethylindolin-6-yl)ä2-ä(4- | |
| EA200601223A1 (ru) | Производные сульфонамида для лечения заболеваний | |
| EA200601141A1 (ru) | Сульфонамидные производные для лечения заболеваний | |
| MY144483A (en) | 1,2,3,4-tetrasubstituted indole for the treatment of respiratory diseases | |
| JO2282B1 (en) | Oxazole derivatives | |
| BR0211972A (pt) | Composição oftálmica | |
| MXPA05009535A (es) | Compuestos de acido n - alquil - hidroxamico - isoindolilo y sus usos farmaceuticos. | |
| EA200801711A1 (ru) | Пролекарства возбуждающих аминокислот | |
| TW200502221A (en) | Novel lactams and uses thereof | |
| EA200600071A1 (ru) | Производные n-фенилпиперазина и способы профилактики или лечения заболеваний, связанных с 5ht-рецептором | |
| TW200505865A (en) | Compounds useful for the treatment of diseases | |
| ATE491453T1 (de) | Verwendung von 4-aminochinolin-verbindungen zur behandlung entzündlicher erkrankungen des auges | |
| WO2005075450A3 (en) | Spiro-benzodioxoles and their use as cb1 antagonists | |
| WO2020165838A9 (en) | Methods for treating ocular surface pain | |
| CA2534634A1 (en) | Azolidinecarbonitriles and their use as dpp-iv inhibitors | |
| ATE464048T1 (de) | Behandlung von alzheimer-krankheit und verwandten zuständen | |
| EA200201232A1 (ru) | Производные сульфонамида | |
| ATE437855T1 (de) | (4,5,6,7-tetrahydro-1h-indol-7- yl)essigsäurederivate zur behandlung von alzheimer-krankheit | |
| MY129575A (en) | Methods, kits and compositions for using pyrrole derivatives againts anxiety |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |