ATE323549T2 - Verfahren zur herstellung von nano- und mikro- teilchen - Google Patents

Verfahren zur herstellung von nano- und mikro- teilchen Download PDF

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Publication number
ATE323549T2
ATE323549T2 AT01970064T AT01970064T ATE323549T2 AT E323549 T2 ATE323549 T2 AT E323549T2 AT 01970064 T AT01970064 T AT 01970064T AT 01970064 T AT01970064 T AT 01970064T AT E323549 T2 ATE323549 T2 AT E323549T2
Authority
AT
Austria
Prior art keywords
carbon dioxide
solubilizing
supercritical
micronic
conditions
Prior art date
Application number
AT01970064T
Other languages
English (en)
Inventor
Ernesto Reverchon
Original Assignee
Micro & Nano Materials Sagl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4563123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE323549(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Micro & Nano Materials Sagl filed Critical Micro & Nano Materials Sagl
Application granted granted Critical
Publication of ATE323549T2 publication Critical patent/ATE323549T2/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01970064T 2001-07-02 2001-09-27 Verfahren zur herstellung von nano- und mikro- teilchen ATE323549T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH12092001 2001-07-02

Publications (1)

Publication Number Publication Date
ATE323549T2 true ATE323549T2 (de) 2006-05-15

Family

ID=4563123

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01970064T ATE323549T2 (de) 2001-07-02 2001-09-27 Verfahren zur herstellung von nano- und mikro- teilchen

Country Status (8)

Country Link
US (1) US7276190B2 (de)
EP (1) EP1401563B2 (de)
AT (1) ATE323549T2 (de)
DE (1) DE60118983T3 (de)
DK (1) DK1401563T4 (de)
ES (1) ES2261469T5 (de)
PT (1) PT1401563E (de)
WO (1) WO2003004142A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US8030194B2 (en) * 2004-09-27 2011-10-04 Technion Research And Development Foundation Ltd. Spray method for producing semiconductor nano-particles
WO2006062980A2 (en) * 2004-12-07 2006-06-15 Nektar Therapeutics Stable non-crystalline formulation comprising tiagabine
EP1904219A4 (de) 2005-07-15 2011-07-27 Map Pharmaceuticals Inc Teilchenbildungsverfahren
US20070023035A1 (en) * 2005-07-29 2007-02-01 Kane Kevin M Method for processing drugs
US20080223136A1 (en) * 2005-08-04 2008-09-18 Tokyo Electron Limited Minute structure inspection device, inspection method, and inspection program
WO2007028421A1 (en) * 2005-09-09 2007-03-15 Universita' Degli Studi Di Padova Process for the production of nano-particles
US20070128291A1 (en) * 2005-12-07 2007-06-07 Tokie Jeffrey H Method and Apparatus for Forming Chromonic Nanoparticles
WO2008058054A2 (en) * 2006-11-06 2008-05-15 Novartis Ag Method for making parenteral pharmaceutical compositions in a unit dose container
CN100444943C (zh) * 2007-02-14 2008-12-24 浙江大学 水力空化增强超临界辅助雾化制备微粒的系统及其方法
RU2356609C1 (ru) * 2008-02-07 2009-05-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт органической химии и технологии", ФГУП "ГосНИИОХТ" Способ получения нано- и микрочастиц водорастворимых веществ с использованием сверхкритического диоксида углерода
US9291139B2 (en) 2008-08-27 2016-03-22 Woodward, Inc. Dual action fuel injection nozzle
EP2181604A1 (de) 2008-11-04 2010-05-05 Feyecon Development & Implementation B.V. Dispersionsstrukturierungsmittel
ES2342140B1 (es) * 2008-12-30 2011-05-17 Consejo Superior Investigacion Procedimiento para la obtencion de micro- o nanoparticulas solidas
EP2579973A4 (de) * 2010-06-14 2017-01-18 Xspray Microparticles Ab Vorrichtung und verfahren zur herstellung von partikeln
JP6921759B2 (ja) 2015-06-04 2021-08-18 クリティテック・インコーポレイテッド 捕集装置および使用法
SG10201913409VA (en) 2016-04-04 2020-03-30 Crititech Inc Methods for solid tumor treatment
SG11201909840TA (en) 2017-06-09 2019-11-28 Crititech Inc Treatment of epithelial cysts by intracystic injection of antineoplastic particles
CN115919815A (zh) 2017-06-14 2023-04-07 克里蒂泰克公司 治疗肺部疾病的方法
KR20200064112A (ko) 2017-10-03 2020-06-05 크리티테크, 인크. 암의 치료를 위한 면역치료제의 전신 전달과 조합된 항신생물성 입자의 국소 전달
EP4190437A1 (de) * 2021-12-03 2023-06-07 SiTec PharmaBio SL Verfahren und vorrichtung zur herstellung von festen mikropartikeln

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348422A (en) * 1978-02-13 1982-09-07 Studiengesellschaft Kohle M.B.H. Process for the direct decaffeination of aqueous coffee extract solutions
DE3937287A1 (de) * 1989-11-09 1991-05-16 Henkel Kgaa Verfahren und anlage zum abtrennen von fettsaeuremonoglycerid
US20020018815A1 (en) * 1992-03-06 2002-02-14 Sievers Robert E. Methods and apparatus for fine particle formation
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
AU709384B2 (en) 1996-03-01 1999-08-26 University Of Kansas, The Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
US6221153B1 (en) * 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
SE9804000D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New composition of matter
GB9828204D0 (en) 1998-12-21 1999-02-17 Smithkline Beecham Plc Process
ES2170008B1 (es) 2000-08-25 2003-05-01 Soc Es Carburos Metalicos Sa Procedimiento para la precipitacion de particulas solidas finamente divididas.

Also Published As

Publication number Publication date
DE60118983D1 (de) 2006-05-24
EP1401563B1 (de) 2006-04-19
DE60118983T2 (de) 2007-01-11
DE60118983T3 (de) 2016-07-07
DK1401563T3 (da) 2006-08-14
EP1401563A1 (de) 2004-03-31
DK1401563T4 (en) 2016-01-11
US20040178529A1 (en) 2004-09-16
ES2261469T5 (es) 2015-12-22
EP1401563B2 (de) 2015-09-16
ES2261469T3 (es) 2006-11-16
WO2003004142A1 (en) 2003-01-16
US7276190B2 (en) 2007-10-02
PT1401563E (pt) 2006-08-31

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